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The map label for this gene is bcd [H]

Identifier: 121610260

GI number: 121610260

Start: 3703640

End: 3704818

Strand: Direct

Name: bcd [H]

Synonym: Veis_3319

Alternate gene names: 121610260

Gene position: 3703640-3704818 (Clockwise)

Preceding gene: 121610258

Following gene: 121610261

Centisome position: 66.53

GC content: 68.79

Gene sequence:

>1179_bases
ATGCCCGTGGCCAGCCCCAGCACCATGAACTTCGATCTCAGTGCAGAGCACCAGGCTTTTGCCGAGTCCGTGTCCCGGTT
CGCCAAAGACCATCTCGCCCCCGCAGCCCTGGCGCGCGCGCACGCCGCGACCTACCCGTGGGAGACCGCCGCCTTGCTCG
CCCGGCAGGGCTTGCTCGGCATCACCTTGCCCGAGGCCGACGGCGGCCAGGGCGGCAGCTTGATGCACGCCGTGCTGGCC
ATCGAACAGGTGGCGCTGGTCTGCCCCAGGAGCGCCGACATCGTGCAGGCCGGCAATTTTGGAGCGCTGCGGACTTTCGC
CGAATACGCCAGCGCCGAGCAAAAGGCGCGCTTCCTGCCCGATCTGCTGGCCGGGCGCACGCTGATGGCGTTGGCCATGA
CCGAGCCGGACGCCGGCTCGGCCGCGACCGATCTCAAGACCAGTGCCCGCCCCGACGGTGGGCATTACGTGATCAACGGC
GCCAAGCTGTTTTCCACCCACAGCCCGGAGGCCGCGCTGTTTCTGGTCTATCTGCGCTTCGGCCCGGGCGTCGCCGGCAT
CGGCTCGATCCTCGTCGAACGCGGGGCGCCGGGGTTCGGGATCGGACCGCCCTCGGGCTTCATGAACGGCGAGCAGTGGT
CGCCGCTGTACTTTGACAACTGCCGGGTGCCCCGGGCCAACCTGCTGCTGGGCGCAGGCGGCTTCAAGCGCCAGATTGCC
GGCTTCAACATCGAGCGGCTGGGCAATGCCGCGCGGGCGCTGGCGCTGGGGCGCCACGCATTCAACCTGGCGCGCGAGCA
TGCGCTGACCCGGCAGCAGTTCGGCCGCGAACTGTGCCAATTCCAGGGGCTGCAATGGAAGTTTGTCGACATGGCGATGA
AGCTCGCGCAGGCCCAGTTGCTGCTCTACCGCGCAGCGCTGGAGGGCGAGCATGGCCTGCCCTCGGCACAGGGCAGCGCG
ATGGCCAAGCTCGCCTGCAACCTGGCGGGCTGGGAGGTGGCCAACGAGGCGATGCAGGTCATGGGCGGCACGGGCTTTTG
CCAGGCGTCGCTGGTCGAGTACTGCGTGCGCCGCACGCGCGGCTGGATGATCGCCGGCGGCTCGATCGAGATGCTCAAGA
ACCGCATCGCCGAAGGGATTTTTGCCAGGGCTTTTCCGCAGCGCGCGGCCAGGCCATGA

Upstream 100 bases:

>100_bases
TGGTTTCAGGCATCACTTTTTCTCATGCCTTGCGGCCAAATCGGAACTGCTGGCCGGCCCATCCGGCAAGCACATTCATG
TCCTTCATGTCCTTTGCTCC

Downstream 100 bases:

>100_bases
GGCCCCCTTTCGTGTGTTCGACCTTCCCAACGGAGACCCCACCATGCAGCGTCGTCATTTTTTGCTGGCTGCCATGGCGC
CGCTGGCGTTCGGCAGCGCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MPVASPSTMNFDLSAEHQAFAESVSRFAKDHLAPAALARAHAATYPWETAALLARQGLLGITLPEADGGQGGSLMHAVLA
IEQVALVCPRSADIVQAGNFGALRTFAEYASAEQKARFLPDLLAGRTLMALAMTEPDAGSAATDLKTSARPDGGHYVING
AKLFSTHSPEAALFLVYLRFGPGVAGIGSILVERGAPGFGIGPPSGFMNGEQWSPLYFDNCRVPRANLLLGAGGFKRQIA
GFNIERLGNAARALALGRHAFNLAREHALTRQQFGRELCQFQGLQWKFVDMAMKLAQAQLLLYRAALEGEHGLPSAQGSA
MAKLACNLAGWEVANEAMQVMGGTGFCQASLVEYCVRRTRGWMIAGGSIEMLKNRIAEGIFARAFPQRAARP

Sequences:

>Translated_392_residues
MPVASPSTMNFDLSAEHQAFAESVSRFAKDHLAPAALARAHAATYPWETAALLARQGLLGITLPEADGGQGGSLMHAVLA
IEQVALVCPRSADIVQAGNFGALRTFAEYASAEQKARFLPDLLAGRTLMALAMTEPDAGSAATDLKTSARPDGGHYVING
AKLFSTHSPEAALFLVYLRFGPGVAGIGSILVERGAPGFGIGPPSGFMNGEQWSPLYFDNCRVPRANLLLGAGGFKRQIA
GFNIERLGNAARALALGRHAFNLAREHALTRQQFGRELCQFQGLQWKFVDMAMKLAQAQLLLYRAALEGEHGLPSAQGSA
MAKLACNLAGWEVANEAMQVMGGTGFCQASLVEYCVRRTRGWMIAGGSIEMLKNRIAEGIFARAFPQRAARP
>Mature_391_residues
PVASPSTMNFDLSAEHQAFAESVSRFAKDHLAPAALARAHAATYPWETAALLARQGLLGITLPEADGGQGGSLMHAVLAI
EQVALVCPRSADIVQAGNFGALRTFAEYASAEQKARFLPDLLAGRTLMALAMTEPDAGSAATDLKTSARPDGGHYVINGA
KLFSTHSPEAALFLVYLRFGPGVAGIGSILVERGAPGFGIGPPSGFMNGEQWSPLYFDNCRVPRANLLLGAGGFKRQIAG
FNIERLGNAARALALGRHAFNLAREHALTRQQFGRELCQFQGLQWKFVDMAMKLAQAQLLLYRAALEGEHGLPSAQGSAM
AKLACNLAGWEVANEAMQVMGGTGFCQASLVEYCVRRTRGWMIAGGSIEMLKNRIAEGIFARAFPQRAARP

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=32.7127659574468, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI4557233, Length=373, Percent_Identity=29.4906166219839, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=29.6791443850267, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI226958412, Length=368, Percent_Identity=28.5326086956522, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI187960098, Length=371, Percent_Identity=27.4932614555256, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI4557231, Length=371, Percent_Identity=27.4932614555256, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI226958414, Length=326, Percent_Identity=28.8343558282209, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI76496475, Length=388, Percent_Identity=29.3814432989691, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4557235, Length=388, Percent_Identity=29.3814432989691, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI21361497, Length=346, Percent_Identity=30.0578034682081, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=28.1167108753316, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4503943, Length=362, Percent_Identity=26.7955801104972, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7669494, Length=362, Percent_Identity=26.7955801104972, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI38505218, Length=390, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI211971008, Length=266, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI48976061, Length=266, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786223, Length=369, Percent_Identity=28.4552845528455, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI87081958, Length=376, Percent_Identity=28.9893617021277, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=30.7277628032345, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17506239, Length=384, Percent_Identity=30.7291666666667, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17533517, Length=378, Percent_Identity=29.6296296296296, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71990804, Length=275, Percent_Identity=34.9090909090909, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=29.4270833333333, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17538396, Length=371, Percent_Identity=30.7277628032345, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17569725, Length=390, Percent_Identity=29.2307692307692, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17534899, Length=386, Percent_Identity=29.2746113989637, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71985184, Length=276, Percent_Identity=32.6086956521739, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=31.8777292576419, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17551932, Length=386, Percent_Identity=26.1658031088083, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=255, Percent_Identity=32.156862745098, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985192, Length=215, Percent_Identity=33.0232558139535, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17505929, Length=369, Percent_Identity=26.8292682926829, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=25.9124087591241, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=271, Percent_Identity=30.6273062730627, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=31.0526315789474, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356377, Length=374, Percent_Identity=28.8770053475936, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=30.2139037433155, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24660351, Length=390, Percent_Identity=27.6923076923077, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21355753, Length=373, Percent_Identity=28.4182305630027, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281363737, Length=282, Percent_Identity=28.0141843971631, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19920834, Length=300, Percent_Identity=27.3333333333333, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41787; Mature: 41655

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVASPSTMNFDLSAEHQAFAESVSRFAKDHLAPAALARAHAATYPWETAALLARQGLLG
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCE
ITLPEADGGQGGSLMHAVLAIEQVALVCPRSADIVQAGNFGALRTFAEYASAEQKARFLP
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
DLLAGRTLMALAMTEPDAGSAATDLKTSARPDGGHYVINGAKLFSTHSPEAALFLVYLRF
HHHHCCCEEEEEECCCCCCCCHHCCCCCCCCCCCEEEEECEEEECCCCCCCEEEEEEEEC
GPGVAGIGSILVERGAPGFGIGPPSGFMNGEQWSPLYFDNCRVPRANLLLGAGGFKRQIA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCHHHHHC
GFNIERLGNAARALALGRHAFNLAREHALTRQQFGRELCQFQGLQWKFVDMAMKLAQAQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LLYRAALEGEHGLPSAQGSAMAKLACNLAGWEVANEAMQVMGGTGFCQASLVEYCVRRTR
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
GWMIAGGSIEMLKNRIAEGIFARAFPQRAARP
CEEEECCCHHHHHHHHHHHHHHHHCHHHCCCC
>Mature Secondary Structure 
PVASPSTMNFDLSAEHQAFAESVSRFAKDHLAPAALARAHAATYPWETAALLARQGLLG
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCE
ITLPEADGGQGGSLMHAVLAIEQVALVCPRSADIVQAGNFGALRTFAEYASAEQKARFLP
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
DLLAGRTLMALAMTEPDAGSAATDLKTSARPDGGHYVINGAKLFSTHSPEAALFLVYLRF
HHHHCCCEEEEEECCCCCCCCHHCCCCCCCCCCCEEEEECEEEECCCCCCCEEEEEEEEC
GPGVAGIGSILVERGAPGFGIGPPSGFMNGEQWSPLYFDNCRVPRANLLLGAGGFKRQIA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCHHHHHC
GFNIERLGNAARALALGRHAFNLAREHALTRQQFGRELCQFQGLQWKFVDMAMKLAQAQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LLYRAALEGEHGLPSAQGSAMAKLACNLAGWEVANEAMQVMGGTGFCQASLVEYCVRRTR
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
GWMIAGGSIEMLKNRIAEGIFARAFPQRAARP
CEEEECCCHHHHHHHHHHHHHHHHCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]