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The map label for this gene is moxY [H]

Identifier: 121610243

GI number: 121610243

Start: 3684611

End: 3685978

Strand: Direct

Name: moxY [H]

Synonym: Veis_3302

Alternate gene names: 121610243

Gene position: 3684611-3685978 (Clockwise)

Preceding gene: 121610242

Following gene: 121610244

Centisome position: 66.19

GC content: 65.79

Gene sequence:

>1368_bases
ATGAGGCTGAAGAATCGCCTGGCGTTGGTCATAGTGCTGTTCCTGTCAACCTTTGTCGGCTGCTATAGCCTGTTGCTGTT
ACTGGAAGTCCCCGAGCGTGCCAATGTCGAGACAGACGGTGCCTTGCCGTGGGTGATCAGCCTGTTGCCAGGCCATGTGG
ACACCAGTCTCCGTGGCGCAGCCGCGCAGCGCCAGGCGCTGGCGACACTGGTGCATGGGTTCGACGGGATCCGCCATGTC
CGGGTCGTGCTGCGCGCACCCGACGGTGCTTTGCTCGCGCGCGCATCCTCGCCTGCCAAGCCGGCGCCGTCCTGGCTGGT
CGCGAGGCTGGCGGGGCCGAAAGCTGCGACACGCAAGAACGTCATGGACGGCAAGCATGTGTTCGCCTACTTCGAGGTGA
CGCCGGCCGCCAGCGACGAACTCACTGAGCTGTGGGCAGACTTCGTGCGCGGCGCGACGCTGGTGGCGGGCCTGTCGCTG
GCCACGATGCTGCTGATCCTGTGGTTCACGTTCCATGCGTTGAAGCCGCTGGACCGGATATGCGCTGCGCTGCGCGCACT
GGCCAAGGGCCGGCAAGACGCCCGCCTGCCGGTCTTTGCCAGCCCGGAGATGCAGGAGATCGCCATGTCGTTCAACCACA
TGGCCGAGCGCCAAGCGGCCTCGAACGCCGAGCGCCAAGCGCTTTTGCGCAAGCTCATCGACAGTGAGGAAAACACGCGG
CGCTCGGTGGCACACGACCTGCACGACGAACTCAGCCCTTATCTGGTCGCTCTCCAGCCACTGGTGCGCACGATGCAGTT
GAAGTGCGCACAGCGCCCCGAGTTGAGCGACTTCGCCGCCACGGTCGACACCTTGATCAGCCACCAGTCACATATCCTGG
CCAAGCTGCGTGCAATCTTGATGGGCTTGCACCCCCCGGAGCTCGAAACGCTGGGGTTGCGTGGCGCCATCGAACGTCTG
GCTGCCCAGCCCCTGCGCAGCGATGACGGGCGGGAGATCGACGTGGTGCTCGATGCGGGCGGTGACTGGCTCGCGTTTGG
TCCGACGCTGGACGTGAGCGTCTATCGCCTGATCCTGGAATGTCTGAACAACGCCCGCCGGCACGCGACGGGCACGCGGG
TCGACATCCGCTTCGACACCGAAGCCAAAGTGCAGGGGCGGGCCATGCTCGCCATCGAGGTCGTCAACGACTTCTCTCCG
GGGCACTCAGGCAGCGGCGGTGGCGGTCTGGGGGTGCCGGGCATGCGCGACCGCTGCGTGGCGCTGGGCGGCAGCTTTGC
CGCAGGAGCGCTGCACGACGATAAGGTGTGGTGCGTGCGCATGCACCTGCCGCTGGATGCGGCTGCGCGAAACGATAGCC
ATGTATGA

Upstream 100 bases:

>100_bases
CGGGGGTTTGCAATGCCGCAAACGCCCCCGGGACGGGACGCGCGGTGCGTGGGGAACCTGGTTCACGCAGCCATGACGGC
CCGATTCGGTTGGCCTGCGC

Downstream 100 bases:

>100_bases
ACACTGAAACCATCCGCACCTTGATCGTTGACGACCATGCCGTGGTGCGTTCGGGCTACCGCAGCTATCTGGAGCAGGTG
CCCGGTTTCCAGGTGGTGGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MRLKNRLALVIVLFLSTFVGCYSLLLLLEVPERANVETDGALPWVISLLPGHVDTSLRGAAAQRQALATLVHGFDGIRHV
RVVLRAPDGALLARASSPAKPAPSWLVARLAGPKAATRKNVMDGKHVFAYFEVTPAASDELTELWADFVRGATLVAGLSL
ATMLLILWFTFHALKPLDRICAALRALAKGRQDARLPVFASPEMQEIAMSFNHMAERQAASNAERQALLRKLIDSEENTR
RSVAHDLHDELSPYLVALQPLVRTMQLKCAQRPELSDFAATVDTLISHQSHILAKLRAILMGLHPPELETLGLRGAIERL
AAQPLRSDDGREIDVVLDAGGDWLAFGPTLDVSVYRLILECLNNARRHATGTRVDIRFDTEAKVQGRAMLAIEVVNDFSP
GHSGSGGGGLGVPGMRDRCVALGGSFAAGALHDDKVWCVRMHLPLDAAARNDSHV

Sequences:

>Translated_455_residues
MRLKNRLALVIVLFLSTFVGCYSLLLLLEVPERANVETDGALPWVISLLPGHVDTSLRGAAAQRQALATLVHGFDGIRHV
RVVLRAPDGALLARASSPAKPAPSWLVARLAGPKAATRKNVMDGKHVFAYFEVTPAASDELTELWADFVRGATLVAGLSL
ATMLLILWFTFHALKPLDRICAALRALAKGRQDARLPVFASPEMQEIAMSFNHMAERQAASNAERQALLRKLIDSEENTR
RSVAHDLHDELSPYLVALQPLVRTMQLKCAQRPELSDFAATVDTLISHQSHILAKLRAILMGLHPPELETLGLRGAIERL
AAQPLRSDDGREIDVVLDAGGDWLAFGPTLDVSVYRLILECLNNARRHATGTRVDIRFDTEAKVQGRAMLAIEVVNDFSP
GHSGSGGGGLGVPGMRDRCVALGGSFAAGALHDDKVWCVRMHLPLDAAARNDSHV
>Mature_455_residues
MRLKNRLALVIVLFLSTFVGCYSLLLLLEVPERANVETDGALPWVISLLPGHVDTSLRGAAAQRQALATLVHGFDGIRHV
RVVLRAPDGALLARASSPAKPAPSWLVARLAGPKAATRKNVMDGKHVFAYFEVTPAASDELTELWADFVRGATLVAGLSL
ATMLLILWFTFHALKPLDRICAALRALAKGRQDARLPVFASPEMQEIAMSFNHMAERQAASNAERQALLRKLIDSEENTR
RSVAHDLHDELSPYLVALQPLVRTMQLKCAQRPELSDFAATVDTLISHQSHILAKLRAILMGLHPPELETLGLRGAIERL
AAQPLRSDDGREIDVVLDAGGDWLAFGPTLDVSVYRLILECLNNARRHATGTRVDIRFDTEAKVQGRAMLAIEVVNDFSP
GHSGSGGGGLGVPGMRDRCVALGGSFAAGALHDDKVWCVRMHLPLDAAARNDSHV

Specific function: Member of the two-component regulatory system moxY/moxX probably involved in the regulation of the methanol dehydrogenase expression. May function as a membrane-associated protein kinase that phosphorylates moxX in response to environmental signals [H]

COG id: COG3851

COG function: function code T; Signal transduction histidine kinase, glucose-6-phosphate specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=226, Percent_Identity=29.646017699115, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR011712 [H]

Pfam domain/function: PF00672 HAMP; PF07730 HisKA_3 [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 49441; Mature: 49441

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKNRLALVIVLFLSTFVGCYSLLLLLEVPERANVETDGALPWVISLLPGHVDTSLRGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHH
AAQRQALATLVHGFDGIRHVRVVLRAPDGALLARASSPAKPAPSWLVARLAGPKAATRKN
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHCCCCHHHHHH
VMDGKHVFAYFEVTPAASDELTELWADFVRGATLVAGLSLATMLLILWFTFHALKPLDRI
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
CAALRALAKGRQDARLPVFASPEMQEIAMSFNHMAERQAASNAERQALLRKLIDSEENTR
HHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHH
RSVAHDLHDELSPYLVALQPLVRTMQLKCAQRPELSDFAATVDTLISHQSHILAKLRAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLHPPELETLGLRGAIERLAAQPLRSDDGREIDVVLDAGGDWLAFGPTLDVSVYRLILE
HCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHH
CLNNARRHATGTRVDIRFDTEAKVQGRAMLAIEVVNDFSPGHSGSGGGGLGVPGMRDRCV
HHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
ALGGSFAAGALHDDKVWCVRMHLPLDAAARNDSHV
HCCCCCCCCCCCCCCEEEEEEECCCCHHCCCCCCC
>Mature Secondary Structure
MRLKNRLALVIVLFLSTFVGCYSLLLLLEVPERANVETDGALPWVISLLPGHVDTSLRGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHH
AAQRQALATLVHGFDGIRHVRVVLRAPDGALLARASSPAKPAPSWLVARLAGPKAATRKN
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHCCCCHHHHHH
VMDGKHVFAYFEVTPAASDELTELWADFVRGATLVAGLSLATMLLILWFTFHALKPLDRI
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
CAALRALAKGRQDARLPVFASPEMQEIAMSFNHMAERQAASNAERQALLRKLIDSEENTR
HHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHH
RSVAHDLHDELSPYLVALQPLVRTMQLKCAQRPELSDFAATVDTLISHQSHILAKLRAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLHPPELETLGLRGAIERLAAQPLRSDDGREIDVVLDAGGDWLAFGPTLDVSVYRLILE
HCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHH
CLNNARRHATGTRVDIRFDTEAKVQGRAMLAIEVVNDFSPGHSGSGGGGLGVPGMRDRCV
HHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
ALGGSFAAGALHDDKVWCVRMHLPLDAAARNDSHV
HCCCCCCCCCCCCCCEEEEEEECCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8392137 [H]