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The map label for this gene is tyrA [H]

Identifier: 121610064

GI number: 121610064

Start: 3469490

End: 3470392

Strand: Direct

Name: tyrA [H]

Synonym: Veis_3122

Alternate gene names: 121610064

Gene position: 3469490-3470392 (Clockwise)

Preceding gene: 121610063

Following gene: 121610065

Centisome position: 62.33

GC content: 65.45

Gene sequence:

>903_bases
ATGTTCGAACAATTGGGACTGATAGGCTGCGGGCTCATGGGCGGCTCGTTCGCGCTGGCCATGAAAAAGACCGGCCTGGT
CAAGCGCGTGGTGGGCTACAGCAAGTCGCCCTCGACCACCGACCGCGCCCGCCGGCTGGGGGTCATCGATGTCGAGGCGC
CGTCGGCCTTGATGGCGGTCTCGGGCGCCGACATCGTGCTGGTGGCCGTGCCGGTGGCCGCTACCGAGGCCACGCTCAAA
GCCATCAAGCATCTGGTCACGCCGCAGATGCTGATCATGGATGTCGGCTCGACCAAGGCCGACGTGGTGCAGTCTGCGCA
ACGCGCGCTGCGCGACCAGGTCGGCTCGTTCGTGCCGGCGCATCCGATCGCGGGCAGCGAGGTCTCGGGCGTCGAGCATG
CCGATGCCGATCTCTACAACGGACGCCAGATCATATTGACCCCGACCGAACTCACCCACACTGACCAAGTGGAACGCGCC
ACCCACCTCTGGCAGGCGCTCGGCTGCCGTGTGACCCGACTGTCGCCGCAGGCGCATGATGGCGCCTTCGCCGCTGTCAG
CCACCTGCCCCATGTGCTGGCTTTTGCCATGATGAACAGCATCATCGGGCAAGACCATGGCGACGATTTCCTGTCGCTCG
CCGGCCCCGGCTTTCGCGACTTCACCCGCATCGCGGCCAGCGACCCCAAGATGTGGCGCGACATATTGCTGTCCAACCGG
CATGAACTGATCGTCCAGTCGAGACGGTTCCGGCAGGCGCTGCACGATATCGAGCAGGCCATGGAAAAAGGCCATGCCCA
GTCTCTGGAAGACCTGCTGACCCTGGCCAGCGAAGCCCGCGCCCACTGGCGCATGGGCGCACAGAAAACGGCCAAGCTGC
GCTCCTCCCCCGTAGACCCGTAG

Upstream 100 bases:

>100_bases
ACAGCCCCCTGTGGCGCGGGCGCTGGAAGAACTGCGCAGCCTGTGCGCGTTCTACAAGGTTCTGGGTGCCTACCCGGTGT
CCACCTGAGGAGCCGTCGCC

Downstream 100 bases:

>100_bases
CCCCCCGTAGCCCGCAGACCACCGCGCCATGTACAGCACCGCCTTCATTGACCTTCCCGCATTGGATGCGGCAGCCGGCG
AGGTCCGGTTGCCCGGCTCC

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MFEQLGLIGCGLMGGSFALAMKKTGLVKRVVGYSKSPSTTDRARRLGVIDVEAPSALMAVSGADIVLVAVPVAATEATLK
AIKHLVTPQMLIMDVGSTKADVVQSAQRALRDQVGSFVPAHPIAGSEVSGVEHADADLYNGRQIILTPTELTHTDQVERA
THLWQALGCRVTRLSPQAHDGAFAAVSHLPHVLAFAMMNSIIGQDHGDDFLSLAGPGFRDFTRIAASDPKMWRDILLSNR
HELIVQSRRFRQALHDIEQAMEKGHAQSLEDLLTLASEARAHWRMGAQKTAKLRSSPVDP

Sequences:

>Translated_300_residues
MFEQLGLIGCGLMGGSFALAMKKTGLVKRVVGYSKSPSTTDRARRLGVIDVEAPSALMAVSGADIVLVAVPVAATEATLK
AIKHLVTPQMLIMDVGSTKADVVQSAQRALRDQVGSFVPAHPIAGSEVSGVEHADADLYNGRQIILTPTELTHTDQVERA
THLWQALGCRVTRLSPQAHDGAFAAVSHLPHVLAFAMMNSIIGQDHGDDFLSLAGPGFRDFTRIAASDPKMWRDILLSNR
HELIVQSRRFRQALHDIEQAMEKGHAQSLEDLLTLASEARAHWRMGAQKTAKLRSSPVDP
>Mature_300_residues
MFEQLGLIGCGLMGGSFALAMKKTGLVKRVVGYSKSPSTTDRARRLGVIDVEAPSALMAVSGADIVLVAVPVAATEATLK
AIKHLVTPQMLIMDVGSTKADVVQSAQRALRDQVGSFVPAHPIAGSEVSGVEHADADLYNGRQIILTPTELTHTDQVERA
THLWQALGCRVTRLSPQAHDGAFAAVSHLPHVLAFAMMNSIIGQDHGDDFLSLAGPGFRDFTRIAASDPKMWRDILLSNR
HELIVQSRRFRQALHDIEQAMEKGHAQSLEDLLTLASEARAHWRMGAQKTAKLRSSPVDP

Specific function: Tyrosine biosynthesis [C]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: 500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR002912
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF01842 ACT; PF02153 PDH [H]

EC number: =1.3.1.12 [H]

Molecular weight: Translated: 32418; Mature: 32418

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEQLGLIGCGLMGGSFALAMKKTGLVKRVVGYSKSPSTTDRARRLGVIDVEAPSALMAV
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCEEEECCCCHHEEE
SGADIVLVAVPVAATEATLKAIKHLVTPQMLIMDVGSTKADVVQSAQRALRDQVGSFVPA
CCCCEEEEEECHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHHHHHCCCCCC
HPIAGSEVSGVEHADADLYNGRQIILTPTELTHTDQVERATHLWQALGCRVTRLSPQAHD
CCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCC
GAFAAVSHLPHVLAFAMMNSIIGQDHGDDFLSLAGPGFRDFTRIAASDPKMWRDILLSNR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCH
HELIVQSRRFRQALHDIEQAMEKGHAQSLEDLLTLASEARAHWRMGAQKTAKLRSSPVDP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MFEQLGLIGCGLMGGSFALAMKKTGLVKRVVGYSKSPSTTDRARRLGVIDVEAPSALMAV
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCEEEECCCCHHEEE
SGADIVLVAVPVAATEATLKAIKHLVTPQMLIMDVGSTKADVVQSAQRALRDQVGSFVPA
CCCCEEEEEECHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHHHHHCCCCCC
HPIAGSEVSGVEHADADLYNGRQIILTPTELTHTDQVERATHLWQALGCRVTRLSPQAHD
CCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCC
GAFAAVSHLPHVLAFAMMNSIIGQDHGDDFLSLAGPGFRDFTRIAASDPKMWRDILLSNR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCH
HELIVQSRRFRQALHDIEQAMEKGHAQSLEDLLTLASEARAHWRMGAQKTAKLRSSPVDP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3106153; 9384377 [H]