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The map label for this gene is pheA [H]

Identifier: 121610063

GI number: 121610063

Start: 3468380

End: 3469477

Strand: Direct

Name: pheA [H]

Synonym: Veis_3121

Alternate gene names: 121610063

Gene position: 3468380-3469477 (Clockwise)

Preceding gene: 121610062

Following gene: 121610064

Centisome position: 62.31

GC content: 66.58

Gene sequence:

>1098_bases
ATGAACCATCCGCAAGCCTCACCCGACCTGTCCAGCCTGCGCGTGCAGATCGACCATATCGACCAGCAACTGCTCGCGCT
GCTGAACCAAAGGGCCTTGGTGGCCGAGCGGGTGGGCGAGGTCAAAAAGCGCGAAGGCACGCCCTTTTTTCGCCCCGACC
GTGTGGCGCAGGTGATAGAAAAAATACAGACCACCAACCCCGGTCCGCTCAAAAGCCCGCATGTGGCCGCCATCTGGCGC
GAAATCATGTCGGCCTGCCTGGCGCTGGAATCGCCGCAGCGCGTGGCCGTGCTGGGGCCGCAAGGCACCTTCTGCGAGCA
GGCGGCGATCGGTTTTTTTGGCGGCGCCGCCGACCTGATGTACTGCGCCAACTTCGATGAAGTCTTCCACGCCACGGCCG
CCGGCAGCGCCCAATACGGCGTGGTGGGGGTGGAGAACTCCACCGAAGGCGTGGTCACACGCTCGCTCGATCTGTTCCTG
CACACCCCCACGCATGTGGTGGGCGAAGTCAGCCTGCTGGTGCGCCACAACCTGCTGCGCACCAGCCATTCGCTCGATGG
CATCCATGCCGTGCTGGCCCACCCGCAGGCGCTGGCGCAATGCCAGGCCTGGCTGTCCAGGCACCTGCCGCATGCCGAGC
GCCGCCCGGTATCGAGCAATGCCGAAGGTGCCCGCCTGGCCACCACCGACCCGGCCTGGGCCGCCTTGTCGAGCGAGCGG
GCGGCGACGCAATTTGGCCTGCACATCGTGGCCCACGCGATTCAGGACGATGCCTACAACCGCACGCGCTTTGCCATCAT
CTGCCTGCCGCACACGCTGCCGACGCCGCCGCCCTCGGGCAAGGATTGCACCAGCCTGGTGGTGTCGGTGCCGAACCGGC
CCGGCGCGGTGCATGATCTGCTGGTGCCGCTCAAGACCCATGGCGTGTCGATGACGCGCTTCGAATCCCGCCCGGCCCGC
ACCGGCCAGTGGGAGTATTACTTCTACATCGACCTCGACGGCCATCCCGCACAGCCCCCTGTGGCGCGGGCGCTGGAAGA
ACTGCGCAGCCTGTGCGCGTTCTACAAGGTTCTGGGTGCCTACCCGGTGTCCACCTGA

Upstream 100 bases:

>100_bases
AGAATTTGAGCAAAAGCGGGCCTGAGAGCTCGTTGCCAGTGGTTGCAAGCGCCCGCGCAGCCTCCCTTGCCACGCACAGC
CTCCATTGCCGCCACCATCC

Downstream 100 bases:

>100_bases
GGAGCCGTCGCCATGTTCGAACAATTGGGACTGATAGGCTGCGGGCTCATGGGCGGCTCGTTCGCGCTGGCCATGAAAAA
GACCGGCCTGGTCAAGCGCG

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNHPQASPDLSSLRVQIDHIDQQLLALLNQRALVAERVGEVKKREGTPFFRPDRVAQVIEKIQTTNPGPLKSPHVAAIWR
EIMSACLALESPQRVAVLGPQGTFCEQAAIGFFGGAADLMYCANFDEVFHATAAGSAQYGVVGVENSTEGVVTRSLDLFL
HTPTHVVGEVSLLVRHNLLRTSHSLDGIHAVLAHPQALAQCQAWLSRHLPHAERRPVSSNAEGARLATTDPAWAALSSER
AATQFGLHIVAHAIQDDAYNRTRFAIICLPHTLPTPPPSGKDCTSLVVSVPNRPGAVHDLLVPLKTHGVSMTRFESRPAR
TGQWEYYFYIDLDGHPAQPPVARALEELRSLCAFYKVLGAYPVST

Sequences:

>Translated_365_residues
MNHPQASPDLSSLRVQIDHIDQQLLALLNQRALVAERVGEVKKREGTPFFRPDRVAQVIEKIQTTNPGPLKSPHVAAIWR
EIMSACLALESPQRVAVLGPQGTFCEQAAIGFFGGAADLMYCANFDEVFHATAAGSAQYGVVGVENSTEGVVTRSLDLFL
HTPTHVVGEVSLLVRHNLLRTSHSLDGIHAVLAHPQALAQCQAWLSRHLPHAERRPVSSNAEGARLATTDPAWAALSSER
AATQFGLHIVAHAIQDDAYNRTRFAIICLPHTLPTPPPSGKDCTSLVVSVPNRPGAVHDLLVPLKTHGVSMTRFESRPAR
TGQWEYYFYIDLDGHPAQPPVARALEELRSLCAFYKVLGAYPVST
>Mature_365_residues
MNHPQASPDLSSLRVQIDHIDQQLLALLNQRALVAERVGEVKKREGTPFFRPDRVAQVIEKIQTTNPGPLKSPHVAAIWR
EIMSACLALESPQRVAVLGPQGTFCEQAAIGFFGGAADLMYCANFDEVFHATAAGSAQYGVVGVENSTEGVVTRSLDLFL
HTPTHVVGEVSLLVRHNLLRTSHSLDGIHAVLAHPQALAQCQAWLSRHLPHAERRPVSSNAEGARLATTDPAWAALSSER
AATQFGLHIVAHAIQDDAYNRTRFAIICLPHTLPTPPPSGKDCTSLVVSVPNRPGAVHDLLVPLKTHGVSMTRFESRPAR
TGQWEYYFYIDLDGHPAQPPVARALEELRSLCAFYKVLGAYPVST

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=373, Percent_Identity=29.7587131367292, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 39789; Mature: 39789

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPQASPDLSSLRVQIDHIDQQLLALLNQRALVAERVGEVKKREGTPFFRPDRVAQVIE
CCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
KIQTTNPGPLKSPHVAAIWREIMSACLALESPQRVAVLGPQGTFCEQAAIGFFGGAADLM
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHH
YCANFDEVFHATAAGSAQYGVVGVENSTEGVVTRSLDLFLHTPTHVVGEVSLLVRHNLLR
HHCCHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHH
TSHSLDGIHAVLAHPQALAQCQAWLSRHLPHAERRPVSSNAEGARLATTDPAWAALSSER
HHCCCCHHHHHHHCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEECCCCHHHHHHHHH
AATQFGLHIVAHAIQDDAYNRTRFAIICLPHTLPTPPPSGKDCTSLVVSVPNRPGAVHDL
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHEEECCCCCCCHHHH
LVPLKTHGVSMTRFESRPARTGQWEYYFYIDLDGHPAQPPVARALEELRSLCAFYKVLGA
HHHHHHCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHC
YPVST
CCCCC
>Mature Secondary Structure
MNHPQASPDLSSLRVQIDHIDQQLLALLNQRALVAERVGEVKKREGTPFFRPDRVAQVIE
CCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
KIQTTNPGPLKSPHVAAIWREIMSACLALESPQRVAVLGPQGTFCEQAAIGFFGGAADLM
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHH
YCANFDEVFHATAAGSAQYGVVGVENSTEGVVTRSLDLFLHTPTHVVGEVSLLVRHNLLR
HHCCHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHH
TSHSLDGIHAVLAHPQALAQCQAWLSRHLPHAERRPVSSNAEGARLATTDPAWAALSSER
HHCCCCHHHHHHHCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEECCCCHHHHHHHHH
AATQFGLHIVAHAIQDDAYNRTRFAIICLPHTLPTPPPSGKDCTSLVVSVPNRPGAVHDL
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHEEECCCCCCCHHHH
LVPLKTHGVSMTRFESRPARTGQWEYYFYIDLDGHPAQPPVARALEELRSLCAFYKVLGA
HHHHHHCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHC
YPVST
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]