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The map label for this gene is serC [H]

Identifier: 121610062

GI number: 121610062

Start: 3467159

End: 3468304

Strand: Direct

Name: serC [H]

Synonym: Veis_3120

Alternate gene names: 121610062

Gene position: 3467159-3468304 (Clockwise)

Preceding gene: 121610061

Following gene: 121610063

Centisome position: 62.28

GC content: 64.31

Gene sequence:

>1146_bases
ATGAAACAAGCGCCCGCCGCCTTTTATGCACCATCCATGAAACGCCCTTACAACTTTTCTGCCGGCCCGGCTGCGATTCC
CGCCGAAGTTCTGGAGCAAGCTGCTGCCGAGATGCTCGACTGGCATGGCTGTGGCATGGGCGTGATGGAGATGAGCCACC
GCGGCAAGGAGTTCCGCTCGATCTGCGAGCAGGCGCAGGCCAAGCTGCGCGAGTTGCTGGCGGTGCCGGCGCAGTTCAAG
ATCTTGTTCATGCAGGGCGGTGGTCTGGCGGAAAACGCCATCGTGCCGCTGAACCTGTCGCGTGCCGGGACGGTCGATTT
CGTGGTCACGGGCAGTTGGAGCCAGAAGTCGCAGCAAGAGGCGCGCAAATACGCAGCGCAAGTCAACGTCGTGGCCTCCA
GTGAAGACACCGGCTTTACCAGCCTGCCCGACCCCGCGACCTGGACCCTGAGCCGGGGGGCGAGCTACCTGCATCTTTGC
AGCAACGAGACCATCAACGGCGTCGAGTTCCAGCAATTGCCGGATCTGCAGGCGCTGGGCAGCGATGCCCCGTTGGTGAT
CGACTTCTCCTCGCATGTCGCCTCGCGCCCTGTCGACTGGTCGCGCGTTGGCCTGGCCTTTGGCGGCGCGCAAAAGAACC
TGGGCCCTGCGGGCCTGACGCTGGTGGTCGTGCGCGAAGACCTGCTCGGCCACGCCCTGCCGGCCTGTCCCAGCGCCTTC
GACTACCGGACGGTGGCCGAGCATCAGTCGATGTACAACACCCCCCCGACCTGGGGGATCTACATCGCGGGTCTGACCTT
CGAGTGGCTGGGGCGCCAGCGGGAAGGGCCGTTCAGCGGCATCGCCGCGATGGAGCAACGCCATATCGCCAAAGCCCAAC
TGCTCTACGACGCGATCGACAACTCCGGGCTGTACCTGAACAAAGTGGTGCCCCACTGCCGCTCGCGGATGAATGTGCCG
TTCTTCCTGCGCGACGAGAGTCGCAACGACGATTTTCTGGCCGGGGCCCGCGAACGGGGTCTGTTGCAGCTCAAGGGCCA
CAAGTCGGTGGGAGGCATGCGCGCGAGCATCTACAACGCCATGCCGCTGGCTGGCGTGCAGGCGCTGGTGGACTACATGC
GAGAATTTGAGCAAAAGCGGGCCTGA

Upstream 100 bases:

>100_bases
GCAGCGCGGACGACGGCGCGCCCGATGCCTGACCCTCCGGGATGCCATCGATGCCATCTTCGCGCCGTATACGCTATCAA
ATGTGAAGCGCAACGAGCTC

Downstream 100 bases:

>100_bases
GAGCTCGTTGCCAGTGGTTGCAAGCGCCCGCGCAGCCTCCCTTGCCACGCACAGCCTCCATTGCCGCCACCATCCATGAA
CCATCCGCAAGCCTCACCCG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKQAPAAFYAPSMKRPYNFSAGPAAIPAEVLEQAAAEMLDWHGCGMGVMEMSHRGKEFRSICEQAQAKLRELLAVPAQFK
ILFMQGGGLAENAIVPLNLSRAGTVDFVVTGSWSQKSQQEARKYAAQVNVVASSEDTGFTSLPDPATWTLSRGASYLHLC
SNETINGVEFQQLPDLQALGSDAPLVIDFSSHVASRPVDWSRVGLAFGGAQKNLGPAGLTLVVVREDLLGHALPACPSAF
DYRTVAEHQSMYNTPPTWGIYIAGLTFEWLGRQREGPFSGIAAMEQRHIAKAQLLYDAIDNSGLYLNKVVPHCRSRMNVP
FFLRDESRNDDFLAGARERGLLQLKGHKSVGGMRASIYNAMPLAGVQALVDYMREFEQKRA

Sequences:

>Translated_381_residues
MKQAPAAFYAPSMKRPYNFSAGPAAIPAEVLEQAAAEMLDWHGCGMGVMEMSHRGKEFRSICEQAQAKLRELLAVPAQFK
ILFMQGGGLAENAIVPLNLSRAGTVDFVVTGSWSQKSQQEARKYAAQVNVVASSEDTGFTSLPDPATWTLSRGASYLHLC
SNETINGVEFQQLPDLQALGSDAPLVIDFSSHVASRPVDWSRVGLAFGGAQKNLGPAGLTLVVVREDLLGHALPACPSAF
DYRTVAEHQSMYNTPPTWGIYIAGLTFEWLGRQREGPFSGIAAMEQRHIAKAQLLYDAIDNSGLYLNKVVPHCRSRMNVP
FFLRDESRNDDFLAGARERGLLQLKGHKSVGGMRASIYNAMPLAGVQALVDYMREFEQKRA
>Mature_381_residues
MKQAPAAFYAPSMKRPYNFSAGPAAIPAEVLEQAAAEMLDWHGCGMGVMEMSHRGKEFRSICEQAQAKLRELLAVPAQFK
ILFMQGGGLAENAIVPLNLSRAGTVDFVVTGSWSQKSQQEARKYAAQVNVVASSEDTGFTSLPDPATWTLSRGASYLHLC
SNETINGVEFQQLPDLQALGSDAPLVIDFSSHVASRPVDWSRVGLAFGGAQKNLGPAGLTLVVVREDLLGHALPACPSAF
DYRTVAEHQSMYNTPPTWGIYIAGLTFEWLGRQREGPFSGIAAMEQRHIAKAQLLYDAIDNSGLYLNKVVPHCRSRMNVP
FFLRDESRNDDFLAGARERGLLQLKGHKSVGGMRASIYNAMPLAGVQALVDYMREFEQKRA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=367, Percent_Identity=46.0490463215259, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI10863955, Length=363, Percent_Identity=41.5977961432507, Blast_Score=283, Evalue=2e-76,
Organism=Escherichia coli, GI1787136, Length=368, Percent_Identity=49.1847826086957, Blast_Score=357, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17506897, Length=371, Percent_Identity=42.8571428571429, Blast_Score=300, Evalue=6e-82,
Organism=Saccharomyces cerevisiae, GI6324758, Length=395, Percent_Identity=37.9746835443038, Blast_Score=278, Evalue=8e-76,
Organism=Drosophila melanogaster, GI21356589, Length=365, Percent_Identity=45.4794520547945, Blast_Score=322, Evalue=4e-88,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 41667; Mature: 41667

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQAPAAFYAPSMKRPYNFSAGPAAIPAEVLEQAAAEMLDWHGCGMGVMEMSHRGKEFRS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHH
ICEQAQAKLRELLAVPAQFKILFMQGGGLAENAIVPLNLSRAGTVDFVVTGSWSQKSQQE
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHH
ARKYAAQVNVVASSEDTGFTSLPDPATWTLSRGASYLHLCSNETINGVEFQQLPDLQALG
HHHHHHHEEEEECCCCCCCCCCCCCCEEEHHCCCCEEEECCCCCCCCEEHHHCCCHHHCC
SDAPLVIDFSSHVASRPVDWSRVGLAFGGAQKNLGPAGLTLVVVREDLLGHALPACPSAF
CCCCEEEEECHHHHCCCCCHHHHHEEECCCCCCCCCCCEEEEEEEHHHHHHHCCCCCCCC
DYRTVAEHQSMYNTPPTWGIYIAGLTFEWLGRQREGPFSGIAAMEQRHIAKAQLLYDAID
CHHHHHHHHHHCCCCCCCEEEEECEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
NSGLYLNKVVPHCRSRMNVPFFLRDESRNDDFLAGARERGLLQLKGHKSVGGMRASIYNA
CCCEEHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCCCCEEEEECCCCCCCHHHHHHHC
MPLAGVQALVDYMREFEQKRA
CCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQAPAAFYAPSMKRPYNFSAGPAAIPAEVLEQAAAEMLDWHGCGMGVMEMSHRGKEFRS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHH
ICEQAQAKLRELLAVPAQFKILFMQGGGLAENAIVPLNLSRAGTVDFVVTGSWSQKSQQE
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHH
ARKYAAQVNVVASSEDTGFTSLPDPATWTLSRGASYLHLCSNETINGVEFQQLPDLQALG
HHHHHHHEEEEECCCCCCCCCCCCCCEEEHHCCCCEEEECCCCCCCCEEHHHCCCHHHCC
SDAPLVIDFSSHVASRPVDWSRVGLAFGGAQKNLGPAGLTLVVVREDLLGHALPACPSAF
CCCCEEEEECHHHHCCCCCHHHHHEEECCCCCCCCCCCEEEEEEEHHHHHHHCCCCCCCC
DYRTVAEHQSMYNTPPTWGIYIAGLTFEWLGRQREGPFSGIAAMEQRHIAKAQLLYDAID
CHHHHHHHHHHCCCCCCCEEEEECEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
NSGLYLNKVVPHCRSRMNVPFFLRDESRNDDFLAGARERGLLQLKGHKSVGGMRASIYNA
CCCEEHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCCCCEEEEECCCCCCCHHHHHHHC
MPLAGVQALVDYMREFEQKRA
CCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA