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The map label for this gene is mmgC [H]

Identifier: 121609885

GI number: 121609885

Start: 3289354

End: 3290493

Strand: Direct

Name: mmgC [H]

Synonym: Veis_2938

Alternate gene names: 121609885

Gene position: 3289354-3290493 (Clockwise)

Preceding gene: 121609883

Following gene: 121609886

Centisome position: 59.09

GC content: 65.53

Gene sequence:

>1140_bases
GTGGATGTGAATCGCACGGTTTTTCGCGCAGACCACGAAATGCTGCGGCCCAGCGCGCGGCGCTTTTTTGAACGCGAGTG
CGTTCCACGCCAAGCCGAATGGGACCAGGCCGGCAGGATCGACCGCCAGACCTGGCTCAAGGCCGGCCGCGAGGGCCTGC
TTTGCGTGGCGGTGCCGGCCGAGTACGGCGGCGGCGGGGGCGACTTCGGCCATGCGGCGATCGTCCTCGAGGAGGCGCAC
CGCGCGGGGGTGTCGGGCGCGGGCTTTTCGCTGCACTCGGACATCATCGCGCCCTACATCGTGCGCCTGGGCACCGAGGC
ACAGAAACAAAAATGGCTGCCGGGCATTTGCCGTGGCGAGCAGATCCTGGCCGTGGCCATCACCGAGCCGGGGGGTGGCT
CGGATGTCAAGGCGATGCGCACCACCGCAGTGCGCGACGGCGATGAATACGTCATCGATGGCAGCAAGATTTTCATCAGC
AACGGCTTGAACTGCGACATGGTCTTGCTGGTGTGCAAGACCTCGCCGGCCGCCGGCGCCAAGGGGGTGAGTCTGATCAT
GGTCGAGGCCGACCGCGCGGGTTTTCGCCGTGGCCGCAAGCTCGATAAGGTGGGCCAGCCCGCAGCCGATACCGCCGAGC
TGTTCTTCGACAATCTGCGCGTCCCCGTTGCCAATCTCCTCGGCCAGGAGAACCAGGGCTTCGCCTACCTGATGCAGGAG
TTGGCCCAGGAGCGCTTGATCATCGCCCTGTACGCAGCCGTCGCGCTCGAGCGCCTGCTCGGCCTCACGCTGGAGTATGT
GAAGCAGCGCCGCGCGTTCGAGCAGACCGTGTGGGATTTCCAGAACACCAAGTTCAAGCTGGCCGATGTCAAGGCGCAGT
CGGTTGCCGTGCGCACGATGGTCGACTACTACCTCGGCGAACACCTGCGCCGCAAACTCAGCGTGCAGGAGGCCGCCATT
GCCAAGATGTACGCCACGGAGGCGCTGTGGAAATGCCTCGACGACATGGTGCAACTGCACGGCGGCTATGGCTACATGCT
GGAGTACCCGATCGCGCGCGCCTTCGCGGACTACCGCGTTTCGCGCGTGGTCGGCGGCGCCAACGAAGTCATGCGCGACC
TCATCGCGCGCAAGCTGTGA

Upstream 100 bases:

>100_bases
CTAGTGATCTCCGCCGGTCGATGGACGATCATGGGACGGGCGCGGCAGGGTTTGCCCCGAGGCCGCCGTTTGCCAGCAGA
TGCACCGACAGGAGCTTCCA

Downstream 100 bases:

>100_bases
GCCGGCCATGGGTGAAAAATAACGGACAAGCGCCATGCTCGATCGGAACCTGATTGGCCACAGCTTCGGCAAGCGCAGCC
TTGTCGTCGAGGAAGGCGCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MDVNRTVFRADHEMLRPSARRFFERECVPRQAEWDQAGRIDRQTWLKAGREGLLCVAVPAEYGGGGGDFGHAAIVLEEAH
RAGVSGAGFSLHSDIIAPYIVRLGTEAQKQKWLPGICRGEQILAVAITEPGGGSDVKAMRTTAVRDGDEYVIDGSKIFIS
NGLNCDMVLLVCKTSPAAGAKGVSLIMVEADRAGFRRGRKLDKVGQPAADTAELFFDNLRVPVANLLGQENQGFAYLMQE
LAQERLIIALYAAVALERLLGLTLEYVKQRRAFEQTVWDFQNTKFKLADVKAQSVAVRTMVDYYLGEHLRRKLSVQEAAI
AKMYATEALWKCLDDMVQLHGGYGYMLEYPIARAFADYRVSRVVGGANEVMRDLIARKL

Sequences:

>Translated_379_residues
MDVNRTVFRADHEMLRPSARRFFERECVPRQAEWDQAGRIDRQTWLKAGREGLLCVAVPAEYGGGGGDFGHAAIVLEEAH
RAGVSGAGFSLHSDIIAPYIVRLGTEAQKQKWLPGICRGEQILAVAITEPGGGSDVKAMRTTAVRDGDEYVIDGSKIFIS
NGLNCDMVLLVCKTSPAAGAKGVSLIMVEADRAGFRRGRKLDKVGQPAADTAELFFDNLRVPVANLLGQENQGFAYLMQE
LAQERLIIALYAAVALERLLGLTLEYVKQRRAFEQTVWDFQNTKFKLADVKAQSVAVRTMVDYYLGEHLRRKLSVQEAAI
AKMYATEALWKCLDDMVQLHGGYGYMLEYPIARAFADYRVSRVVGGANEVMRDLIARKL
>Mature_379_residues
MDVNRTVFRADHEMLRPSARRFFERECVPRQAEWDQAGRIDRQTWLKAGREGLLCVAVPAEYGGGGGDFGHAAIVLEEAH
RAGVSGAGFSLHSDIIAPYIVRLGTEAQKQKWLPGICRGEQILAVAITEPGGGSDVKAMRTTAVRDGDEYVIDGSKIFIS
NGLNCDMVLLVCKTSPAAGAKGVSLIMVEADRAGFRRGRKLDKVGQPAADTAELFFDNLRVPVANLLGQENQGFAYLMQE
LAQERLIIALYAAVALERLLGLTLEYVKQRRAFEQTVWDFQNTKFKLADVKAQSVAVRTMVDYYLGEHLRRKLSVQEAAI
AKMYATEALWKCLDDMVQLHGGYGYMLEYPIARAFADYRVSRVVGGANEVMRDLIARKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=46.1538461538462, Blast_Score=350, Evalue=1e-96,
Organism=Homo sapiens, GI226958412, Length=372, Percent_Identity=32.7956989247312, Blast_Score=218, Evalue=5e-57,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=33.9233038348083, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI7656849, Length=359, Percent_Identity=33.4261838440111, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=29.8666666666667, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI4557233, Length=369, Percent_Identity=33.0623306233062, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI21361497, Length=375, Percent_Identity=32.2666666666667, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI76496475, Length=375, Percent_Identity=32.5333333333333, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI4557235, Length=375, Percent_Identity=32.5333333333333, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=28.7234042553192, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=28.7234042553192, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI38505218, Length=356, Percent_Identity=26.685393258427, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI48976061, Length=349, Percent_Identity=27.7936962750716, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI211971008, Length=349, Percent_Identity=27.7936962750716, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4503943, Length=384, Percent_Identity=23.4375, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI7669494, Length=286, Percent_Identity=24.8251748251748, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87081958, Length=351, Percent_Identity=27.9202279202279, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786223, Length=330, Percent_Identity=26.3636363636364, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=33.42175066313, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI17533517, Length=372, Percent_Identity=32.5268817204301, Blast_Score=207, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=30.6068601583113, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17508101, Length=362, Percent_Identity=31.2154696132597, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=30.6666666666667, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=34.9295774647887, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=36.6906474820144, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17570075, Length=375, Percent_Identity=29.3333333333333, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=29.0322580645161, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17569725, Length=371, Percent_Identity=29.6495956873315, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17534899, Length=370, Percent_Identity=30.2702702702703, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI32563615, Length=227, Percent_Identity=33.920704845815, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=315, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=28.4132841328413, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17562446, Length=287, Percent_Identity=27.5261324041812, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=25, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=24.6031746031746, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21355753, Length=384, Percent_Identity=33.59375, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=30.7901907356948, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24666513, Length=378, Percent_Identity=28.5714285714286, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI281363737, Length=398, Percent_Identity=30.1507537688442, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24646207, Length=366, Percent_Identity=30.327868852459, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24660351, Length=373, Percent_Identity=30.2949061662198, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI19920834, Length=371, Percent_Identity=23.7196765498652, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41995; Mature: 41995

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVNRTVFRADHEMLRPSARRFFERECVPRQAEWDQAGRIDRQTWLKAGREGLLCVAVPA
CCCCCHHHHCCHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECC
EYGGGGGDFGHAAIVLEEAHRAGVSGAGFSLHSDIIAPYIVRLGTEAQKQKWLPGICRGE
CCCCCCCCCCHHEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCC
QILAVAITEPGGGSDVKAMRTTAVRDGDEYVIDGSKIFISNGLNCDMVLLVCKTSPAAGA
EEEEEEEECCCCCCCHHHHHHHHHCCCCCEEECCCEEEEECCCCCEEEEEEEECCCCCCC
KGVSLIMVEADRAGFRRGRKLDKVGQPAADTAELFFDNLRVPVANLLGQENQGFAYLMQE
CCEEEEEEECCHHHHHCCCCHHHCCCCCCHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHH
LAQERLIIALYAAVALERLLGLTLEYVKQRRAFEQTVWDFQNTKFKLADVKAQSVAVRTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHH
VDYYLGEHLRRKLSVQEAAIAKMYATEALWKCLDDMVQLHGGYGYMLEYPIARAFADYRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
SRVVGGANEVMRDLIARKL
HHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDVNRTVFRADHEMLRPSARRFFERECVPRQAEWDQAGRIDRQTWLKAGREGLLCVAVPA
CCCCCHHHHCCHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECC
EYGGGGGDFGHAAIVLEEAHRAGVSGAGFSLHSDIIAPYIVRLGTEAQKQKWLPGICRGE
CCCCCCCCCCHHEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCC
QILAVAITEPGGGSDVKAMRTTAVRDGDEYVIDGSKIFISNGLNCDMVLLVCKTSPAAGA
EEEEEEEECCCCCCCHHHHHHHHHCCCCCEEECCCEEEEECCCCCEEEEEEEECCCCCCC
KGVSLIMVEADRAGFRRGRKLDKVGQPAADTAELFFDNLRVPVANLLGQENQGFAYLMQE
CCEEEEEEECCHHHHHCCCCHHHCCCCCCHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHH
LAQERLIIALYAAVALERLLGLTLEYVKQRRAFEQTVWDFQNTKFKLADVKAQSVAVRTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHH
VDYYLGEHLRRKLSVQEAAIAKMYATEALWKCLDDMVQLHGGYGYMLEYPIARAFADYRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
SRVVGGANEVMRDLIARKL
HHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]