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The map label for this gene is amn [H]

Identifier: 120612882

GI number: 120612882

Start: 4703747

End: 4705228

Strand: Direct

Name: amn [H]

Synonym: Aave_4246

Alternate gene names: 120612882

Gene position: 4703747-4705228 (Clockwise)

Preceding gene: 120612878

Following gene: 120612883

Centisome position: 87.87

GC content: 69.23

Gene sequence:

>1482_bases
ATGGCCCAGATCCCAGAATTCACAGAGCCCACCTTCCACTCCGATCCCGCAGAAGCGCTCGCCCAGGTCCAGCGCATCTA
CCAGGAACAGATCGGCCACCTGCGCAACGCCATGCAGCGCTTCGTGGCCGGCGAGACGCCGAACGGCCACGTGCGGGCCT
TCTACCCTTTCGTGCGGGTGCAGACCACCACGGTGGCGCGCGCGGCCACGCAACTGGCCTACGGCTTCGTGGAAGGGCCG
GGCCGCTACGAGACCACCCTCACCCGCCCCGACCTGTTCGCGCGCTACTACGCCGAGCAGTTCCGGCTGCTGCGCGCCAG
CCACAACGTCGAGCTGGAGGTGGGCATCAGCAGCCAGCCCATCCCCATCCACTTCTCCTTCGCCGAGCATGACCACATCG
AGGGCACGCTCACGGCCGAGCGCCGCATGCTGATGCGCGACGTGTTCGACCTGCCCGACCTCGCCGCCATGGACGACGGC
ATCGCCAACGGCACCTGGGAGCCGCGCACGGGCGAGGCGCATCCGCTGTCGCTGTTCACCGCGCCGCGCGTGGACTACTC
GCTGCACCGCCTGCGCCACTACACGGGCACTGCGCCCGAGTGGTTCCAGAACTTCGTGCTGTTCACCAATTACCAGTTCT
ACATCGACGAATTCGTGCGCCTGGGCCACGCCGAGATGGCGAACCCCGACAGCGAATACGTGGCCTTCATCGAGCCCGGC
AACGTGGTCACGCGCCGTACCGGCCTGCCCGCCGAGGCCGGCGACGAGCTCGGCGTGCCGCCGCCGCGCCTGCCGCAGAT
GCCCGCCTACCACCTCGTGCGCGCCGACCGCAGCGGCACCAGCATGGTCAACATCGGCGTGGGCCCGTCGAACGCCAAGA
CCATCACCGACCACATCGCCGTGCTGCGCCCGCACGCCTGGATGATGCTGGGCCACTGCGCGGGCCTGCGCAACAGCCAG
CAGCTGGGCGACTACGTGCTGGCCCATGCCTACGTGCGCGAGGACCACGTGCTCGACGAAGAGCTGCCCCTGTGGGTGCC
GATCCCGGCGCTGGCCGAGATCCAGCTCGCGCTGCAGCAGGCGGTGGCGGACGTGACCCGCGTGCCCGAGGACCAGCTCA
AGCGCATCATGCGCACCGGCACCGTGGCCAGCACCGACAACCGCAACTGGGAACTGCTGCCCGACAACATGCCCCAGCGG
CGCTTCAGCCAGAGCCGCGCCGTGGCGCTGGACATGGAAAGCGCGACGATCGCCGCCAACGGCTTCCGCTTCCGCGTGCC
CTACGGCACGCTGCTGTGCGTGTCCGACAAGCCGCTGCACGGCGAGATCAAGCTGCCGGGCATGGCCAACCACTTCTACC
GCGAGCGCGTGGACCAGCACCTGCGCATCGGCATGCGCGCCATCGATATCCTGCGCGCCGGCGGCGTGAGCCGCCTGCAC
AGCCGCAAGCTGCGCAGCTTCGCGGAAGTCGCCTTCCAGTAG

Upstream 100 bases:

>100_bases
GCCCGGGGAGCCGGGGAAGGGGGGGAGGGTTGCATCGCCCGATTATCCCGGCCCGGCCCTTTCCCGGACGCGCCATGCGG
CGGGCGTGGACAATACGCCC

Downstream 100 bases:

>100_bases
GCGGGACGCCGCGGCGGCCACGCCACCACGCCGATGCCGCCGATGGCACTGGATTTCGTCACGCTGCTGGCCGTCACGGC
CACCAACCTGTTCATGCTCT

Product: AMP nucleosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MAQIPEFTEPTFHSDPAEALAQVQRIYQEQIGHLRNAMQRFVAGETPNGHVRAFYPFVRVQTTTVARAATQLAYGFVEGP
GRYETTLTRPDLFARYYAEQFRLLRASHNVELEVGISSQPIPIHFSFAEHDHIEGTLTAERRMLMRDVFDLPDLAAMDDG
IANGTWEPRTGEAHPLSLFTAPRVDYSLHRLRHYTGTAPEWFQNFVLFTNYQFYIDEFVRLGHAEMANPDSEYVAFIEPG
NVVTRRTGLPAEAGDELGVPPPRLPQMPAYHLVRADRSGTSMVNIGVGPSNAKTITDHIAVLRPHAWMMLGHCAGLRNSQ
QLGDYVLAHAYVREDHVLDEELPLWVPIPALAEIQLALQQAVADVTRVPEDQLKRIMRTGTVASTDNRNWELLPDNMPQR
RFSQSRAVALDMESATIAANGFRFRVPYGTLLCVSDKPLHGEIKLPGMANHFYRERVDQHLRIGMRAIDILRAGGVSRLH
SRKLRSFAEVAFQ

Sequences:

>Translated_493_residues
MAQIPEFTEPTFHSDPAEALAQVQRIYQEQIGHLRNAMQRFVAGETPNGHVRAFYPFVRVQTTTVARAATQLAYGFVEGP
GRYETTLTRPDLFARYYAEQFRLLRASHNVELEVGISSQPIPIHFSFAEHDHIEGTLTAERRMLMRDVFDLPDLAAMDDG
IANGTWEPRTGEAHPLSLFTAPRVDYSLHRLRHYTGTAPEWFQNFVLFTNYQFYIDEFVRLGHAEMANPDSEYVAFIEPG
NVVTRRTGLPAEAGDELGVPPPRLPQMPAYHLVRADRSGTSMVNIGVGPSNAKTITDHIAVLRPHAWMMLGHCAGLRNSQ
QLGDYVLAHAYVREDHVLDEELPLWVPIPALAEIQLALQQAVADVTRVPEDQLKRIMRTGTVASTDNRNWELLPDNMPQR
RFSQSRAVALDMESATIAANGFRFRVPYGTLLCVSDKPLHGEIKLPGMANHFYRERVDQHLRIGMRAIDILRAGGVSRLH
SRKLRSFAEVAFQ
>Mature_492_residues
AQIPEFTEPTFHSDPAEALAQVQRIYQEQIGHLRNAMQRFVAGETPNGHVRAFYPFVRVQTTTVARAATQLAYGFVEGPG
RYETTLTRPDLFARYYAEQFRLLRASHNVELEVGISSQPIPIHFSFAEHDHIEGTLTAERRMLMRDVFDLPDLAAMDDGI
ANGTWEPRTGEAHPLSLFTAPRVDYSLHRLRHYTGTAPEWFQNFVLFTNYQFYIDEFVRLGHAEMANPDSEYVAFIEPGN
VVTRRTGLPAEAGDELGVPPPRLPQMPAYHLVRADRSGTSMVNIGVGPSNAKTITDHIAVLRPHAWMMLGHCAGLRNSQQ
LGDYVLAHAYVREDHVLDEELPLWVPIPALAEIQLALQQAVADVTRVPEDQLKRIMRTGTVASTDNRNWELLPDNMPQRR
FSQSRAVALDMESATIAANGFRFRVPYGTLLCVSDKPLHGEIKLPGMANHFYRERVDQHLRIGMRAIDILRAGGVSRLHS
RKLRSFAEVAFQ

Specific function: Involved in regulation of AMP concentrations [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788293, Length=488, Percent_Identity=50.8196721311475, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011271
- InterPro:   IPR018953
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF10423 AMNp_N; PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.4 [H]

Molecular weight: Translated: 55652; Mature: 55521

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQIPEFTEPTFHSDPAEALAQVQRIYQEQIGHLRNAMQRFVAGETPNGHVRAFYPFVRV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEE
QTTTVARAATQLAYGFVEGPGRYETTLTRPDLFARYYAEQFRLLRASHNVELEVGISSQP
EHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
IPIHFSFAEHDHIEGTLTAERRMLMRDVFDLPDLAAMDDGIANGTWEPRTGEAHPLSLFT
CEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEE
APRVDYSLHRLRHYTGTAPEWFQNFVLFTNYQFYIDEFVRLGHAEMANPDSEYVAFIEPG
CCCCCHHHHHHHHHCCCCHHHHHCEEEEECHHHHHHHHHHHCCHHCCCCCCCEEEEECCC
NVVTRRTGLPAEAGDELGVPPPRLPQMPAYHLVRADRSGTSMVNIGVGPSNAKTITDHIA
CEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCCEEEEECCCCCCCHHHHHHHH
VLRPHAWMMLGHCAGLRNSQQLGDYVLAHAYVREDHVLDEELPLWVPIPALAEIQLALQQ
HHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHH
AVADVTRVPEDQLKRIMRTGTVASTDNRNWELLPDNMPQRRFSQSRAVALDMESATIAAN
HHHHHHCCCHHHHHHHHHHCCEECCCCCCCEECCCCCCHHHHHCCCEEEEEECCCEEEEC
GFRFRVPYGTLLCVSDKPLHGEIKLPGMANHFYRERVDQHLRIGMRAIDILRAGGVSRLH
CEEEECCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SRKLRSFAEVAFQ
HHHHHHHHHHHCC
>Mature Secondary Structure 
AQIPEFTEPTFHSDPAEALAQVQRIYQEQIGHLRNAMQRFVAGETPNGHVRAFYPFVRV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEE
QTTTVARAATQLAYGFVEGPGRYETTLTRPDLFARYYAEQFRLLRASHNVELEVGISSQP
EHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
IPIHFSFAEHDHIEGTLTAERRMLMRDVFDLPDLAAMDDGIANGTWEPRTGEAHPLSLFT
CEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEE
APRVDYSLHRLRHYTGTAPEWFQNFVLFTNYQFYIDEFVRLGHAEMANPDSEYVAFIEPG
CCCCCHHHHHHHHHCCCCHHHHHCEEEEECHHHHHHHHHHHCCHHCCCCCCCEEEEECCC
NVVTRRTGLPAEAGDELGVPPPRLPQMPAYHLVRADRSGTSMVNIGVGPSNAKTITDHIA
CEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCCEEEEECCCCCCCHHHHHHHH
VLRPHAWMMLGHCAGLRNSQQLGDYVLAHAYVREDHVLDEELPLWVPIPALAEIQLALQQ
HHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHH
AVADVTRVPEDQLKRIMRTGTVASTDNRNWELLPDNMPQRRFSQSRAVALDMESATIAAN
HHHHHHCCCHHHHHHHHHHCCEECCCCCCCEECCCCCCHHHHHCCCEEEEEECCCEEEEC
GFRFRVPYGTLLCVSDKPLHGEIKLPGMANHFYRERVDQHLRIGMRAIDILRAGGVSRLH
CEEEECCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SRKLRSFAEVAFQ
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]