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The map label for this gene is nanK [H]

Identifier: 120612849

GI number: 120612849

Start: 4669385

End: 4670320

Strand: Reverse

Name: nanK [H]

Synonym: Aave_4213

Alternate gene names: 120612849

Gene position: 4670320-4669385 (Counterclockwise)

Preceding gene: 120612858

Following gene: 120612845

Centisome position: 87.25

GC content: 72.65

Gene sequence:

>936_bases
ATGAGAGCTTGTATCGACATAGGGGGAACGAAGGTCGCGGTGGCGCTGGCGCCCGCGGGAACGGACCGGGCCGCGCTCGT
GGCGCGGCGCAGCGAGCCGACCGTGAAGGAAGGGCCGCCCGACGCGCTGGCGCGCCAGTGCCTGCGCATGGTGGACGAGG
CCTGTGCCGAGGCCGGCATATCGCGCGCGCAATTGCAGTCCACCGGCGTGGCGAGTTGCGGGCCATTTATCCTGCAGGAC
GGCATGGTCGAGGTCTCCACGCCGAACATCTGCGGCGGCCTGCCCGGTGCCGACCGCAGCCTGCTGCCCAACGACTGGAC
GAGCATCCCGCTGCAGGCGCCGCTGGCCGAAGCCCTGGGCCGCGTGAACGTGCAGAACGACGCGGTGGCGGCCCTGGTGG
CCGAACGCCGCTGGGGGGCGCTGCAGGGGCAGGACCACTGTGCCTACGTCACCTGGAGCACCGGCGTCGGCGTGGGCCTG
TGCGTGGACGGCAGCGTGCTGCGCGGCAAGAACGGCAACGCGGGGCACGCGGGCCACAGCTTTTCCAGCGACGGCCCGCC
CGAGGCCGCCTGCGGCTGCGGCAACGTGGGTGACGTGGAATCGCTGGTGGCGGGCAACGCCATCCCGCGCCGCTGGGGCC
GCGATGCCGGCGGCCTGATCGGCGCCGCGCGCCAGGGGGATGCCGCCGCCGCCGAGGCCGTGGCACAGATGTGCCGCGTG
CTCGGCCGCATGCTCTACAACCTCGTCGCCATCCTGGACCTGCAGCGCATCAGCGTCGGCGGGAGCGTATTCCTGCATCA
CCAGGATTTCCTGCTGCCTCGCCTGCAGGCCGAAGTATCGGGCCGCCTGCCCGCGCTCACCGGCGGCGTGCTGGTGGTGC
CGGCCGGCCTGGGGCACCAGATAGGGGATTACGCGGCGCTTGCCATGGCCGGCTGA

Upstream 100 bases:

>100_bases
CTACACTGCAGCCACGCCGGTTGCATCCATACTGCCGGCTCGATGTTTCACGGCGCGCGCCGGCATGGCGCGGCGCCTTT
TCCGATCGACCGAGGTGGCG

Downstream 100 bases:

>100_bases
GCGCGGGCAGGCTCAGGGCCCGGCGGCCGGAGTGCTGGCGGTGACGGCGGCTCCGTAGAGCGCCAGCAGGCCCACGACGT
GCCCGATGGCGACGCCGGGC

Product: glucokinase

Products: NA

Alternate protein names: ManNAc kinase; N-acetyl-D-mannosamine kinase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRACIDIGGTKVAVALAPAGTDRAALVARRSEPTVKEGPPDALARQCLRMVDEACAEAGISRAQLQSTGVASCGPFILQD
GMVEVSTPNICGGLPGADRSLLPNDWTSIPLQAPLAEALGRVNVQNDAVAALVAERRWGALQGQDHCAYVTWSTGVGVGL
CVDGSVLRGKNGNAGHAGHSFSSDGPPEAACGCGNVGDVESLVAGNAIPRRWGRDAGGLIGAARQGDAAAAEAVAQMCRV
LGRMLYNLVAILDLQRISVGGSVFLHHQDFLLPRLQAEVSGRLPALTGGVLVVPAGLGHQIGDYAALAMAG

Sequences:

>Translated_311_residues
MRACIDIGGTKVAVALAPAGTDRAALVARRSEPTVKEGPPDALARQCLRMVDEACAEAGISRAQLQSTGVASCGPFILQD
GMVEVSTPNICGGLPGADRSLLPNDWTSIPLQAPLAEALGRVNVQNDAVAALVAERRWGALQGQDHCAYVTWSTGVGVGL
CVDGSVLRGKNGNAGHAGHSFSSDGPPEAACGCGNVGDVESLVAGNAIPRRWGRDAGGLIGAARQGDAAAAEAVAQMCRV
LGRMLYNLVAILDLQRISVGGSVFLHHQDFLLPRLQAEVSGRLPALTGGVLVVPAGLGHQIGDYAALAMAG
>Mature_311_residues
MRACIDIGGTKVAVALAPAGTDRAALVARRSEPTVKEGPPDALARQCLRMVDEACAEAGISRAQLQSTGVASCGPFILQD
GMVEVSTPNICGGLPGADRSLLPNDWTSIPLQAPLAEALGRVNVQNDAVAALVAERRWGALQGQDHCAYVTWSTGVGVGL
CVDGSVLRGKNGNAGHAGHSFSSDGPPEAACGCGNVGDVESLVAGNAIPRRWGRDAGGLIGAARQGDAAAAEAVAQMCRV
LGRMLYNLVAILDLQRISVGGSVFLHHQDFLLPRLQAEVSGRLPALTGGVLVVPAGLGHQIGDYAALAMAG

Specific function: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NanK subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082230, Length=272, Percent_Identity=33.8235294117647, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786891, Length=205, Percent_Identity=27.3170731707317, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.60 [H]

Molecular weight: Translated: 31751; Mature: 31751

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRACIDIGGTKVAVALAPAGTDRAALVARRSEPTVKEGPPDALARQCLRMVDEACAEAGI
CCCEEECCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
SRAQLQSTGVASCGPFILQDGMVEVSTPNICGGLPGADRSLLPNDWTSIPLQAPLAEALG
CHHHHHHCCCCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHC
RVNVQNDAVAALVAERRWGALQGQDHCAYVTWSTGVGVGLCVDGSVLRGKNGNAGHAGHS
CCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCEEECCCCCCCCCCCC
FSSDGPPEAACGCGNVGDVESLVAGNAIPRRWGRDAGGLIGAARQGDAAAAEAVAQMCRV
CCCCCCCHHHCCCCCCCCHHHHHHCCCCCHHHCCCCCCCEECCCCCCHHHHHHHHHHHHH
LGRMLYNLVAILDLQRISVGGSVFLHHQDFLLPRLQAEVSGRLPALTGGVLVVPAGLGHQ
HHHHHHHHHHHHHHHHEECCCEEEEECCHHHHHHHHHHHCCCCCEEECCEEEEECCCCCH
IGDYAALAMAG
HHHHHHHEECC
>Mature Secondary Structure
MRACIDIGGTKVAVALAPAGTDRAALVARRSEPTVKEGPPDALARQCLRMVDEACAEAGI
CCCEEECCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
SRAQLQSTGVASCGPFILQDGMVEVSTPNICGGLPGADRSLLPNDWTSIPLQAPLAEALG
CHHHHHHCCCCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHC
RVNVQNDAVAALVAERRWGALQGQDHCAYVTWSTGVGVGLCVDGSVLRGKNGNAGHAGHS
CCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCEEECCCCCCCCCCCC
FSSDGPPEAACGCGNVGDVESLVAGNAIPRRWGRDAGGLIGAARQGDAAAAEAVAQMCRV
CCCCCCCHHHCCCCCCCCHHHHHHCCCCCHHHCCCCCCCEECCCCCCHHHHHHHHHHHHH
LGRMLYNLVAILDLQRISVGGSVFLHHQDFLLPRLQAEVSGRLPALTGGVLVVPAGLGHQ
HHHHHHHHHHHHHHHHEECCCEEEEECCHHHHHHHHHHHCCCCCEEECCEEEEECCCCCH
IGDYAALAMAG
HHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA