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The map label for this gene is rbsK [H]

Identifier: 120612836

GI number: 120612836

Start: 4654517

End: 4655497

Strand: Direct

Name: rbsK [H]

Synonym: Aave_4200

Alternate gene names: 120612836

Gene position: 4654517-4655497 (Clockwise)

Preceding gene: 120612835

Following gene: 120612837

Centisome position: 86.96

GC content: 72.99

Gene sequence:

>981_bases
ATGACCGTCTCTTCCCGCTCCGCTCAGGAGAACCATTCCCGCTCCGCTATGCCGCGCATCGCCGTCGTGGGCAGTCTCAA
CATGGACATCGTCCTGCGCGTTCCCCGGGCCCCCGGCGCGGGCGAGACCGTGATGGCCGATTCACTGCACCATATTCCCG
GGGGCAAGGGCGGCAACCAGGCGGTGGCCTGCGCCCGCCAGGGCGCACGGGTGCATCTGCTGGGCCGCGTCGGGAACGAT
GCGCACGGCGCGGCGCTGCGCGCGGCACTGGAAGCGGACGCCATCGACCATGCCGGCGTTCAGACGGATCCCGAAGCCCC
CACCGGCATCGCCTGCATCACGGTGGAATCCACCGCGCAGAACCGGATCGTCGTCGTCGGCGGGGCGAACGCCCGCTTCG
AGGTCGATGCGCGGGCCCTGGACACGGCGCTGCAGGGCGCGAGCAACCTGCTGCTGCAGTTCGAGGTGCCCCTGCCCCAG
GTCATGGCCGCCGCCAGGCAGGCGCGGCAGCGTGCCTGTCCCGTGGTGCTCAATCCTTCGCCCATGCAGCCGATTCCCGA
CGTCCTCTGGCCGCTGGTGGACACCCTGGTGGCCAACGAGGTGGAAGCCGCGCTGTTCGCCGACTGCGACGTGCAGACGC
CCGAAGACGCGGCCCATGCGGCCCGCCTGCTGCGCGCCCGCGGTCCCCGGCAGGTGGTGGTGACGCTGGGCGCGGCGGGT
GCCGTGGCCTGCGACGGCAGCGGCTGCCGCCACCATCCGGGCCTGCGCGTGGACGCCGTGGACACCACGGCCGCGGGCGA
CACTTTCCTGGGCGCCCTGACCGTCGCCCTGGCGCGCGGCGAATCGCTCGACCTGGCGGTGCAGACCGGCGTCCGCGCCG
CGGCGCTGTGCGTGACCCGTCCGGGCGCGCAGCCATCGATCCCCACGCGCGCCGAAGTGGCCGCATCCCCCATGCCCCCT
GAATGGAGCCGCATCGCATGA

Upstream 100 bases:

>100_bases
TGCAACCGGAGCTGCGGCTGCGCGCCTCGACCGCGGCATTGCCCCAGGGCCCCGTTTCCACCGCCGCGCCGCACGGCCGT
TTTCCTTCCCGCCATCCCGA

Downstream 100 bases:

>100_bases
AACGCACCGCACTGCTGCACGCCGACCTGTCCCGCGCCATCGCCGCCCTGGGCCATGGCGACATGATCGTCATCGGCGAT
GCCGGCCTGCCGATTCCGCC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTVSSRSAQENHSRSAMPRIAVVGSLNMDIVLRVPRAPGAGETVMADSLHHIPGGKGGNQAVACARQGARVHLLGRVGND
AHGAALRAALEADAIDHAGVQTDPEAPTGIACITVESTAQNRIVVVGGANARFEVDARALDTALQGASNLLLQFEVPLPQ
VMAAARQARQRACPVVLNPSPMQPIPDVLWPLVDTLVANEVEAALFADCDVQTPEDAAHAARLLRARGPRQVVVTLGAAG
AVACDGSGCRHHPGLRVDAVDTTAAGDTFLGALTVALARGESLDLAVQTGVRAAALCVTRPGAQPSIPTRAEVAASPMPP
EWSRIA

Sequences:

>Translated_326_residues
MTVSSRSAQENHSRSAMPRIAVVGSLNMDIVLRVPRAPGAGETVMADSLHHIPGGKGGNQAVACARQGARVHLLGRVGND
AHGAALRAALEADAIDHAGVQTDPEAPTGIACITVESTAQNRIVVVGGANARFEVDARALDTALQGASNLLLQFEVPLPQ
VMAAARQARQRACPVVLNPSPMQPIPDVLWPLVDTLVANEVEAALFADCDVQTPEDAAHAARLLRARGPRQVVVTLGAAG
AVACDGSGCRHHPGLRVDAVDTTAAGDTFLGALTVALARGESLDLAVQTGVRAAALCVTRPGAQPSIPTRAEVAASPMPP
EWSRIA
>Mature_325_residues
TVSSRSAQENHSRSAMPRIAVVGSLNMDIVLRVPRAPGAGETVMADSLHHIPGGKGGNQAVACARQGARVHLLGRVGNDA
HGAALRAALEADAIDHAGVQTDPEAPTGIACITVESTAQNRIVVVGGANARFEVDARALDTALQGASNLLLQFEVPLPQV
MAAARQARQRACPVVLNPSPMQPIPDVLWPLVDTLVANEVEAALFADCDVQTPEDAAHAARLLRARGPRQVVVTLGAAGA
VACDGSGCRHHPGLRVDAVDTTAAGDTFLGALTVALARGESLDLAVQTGVRAAALCVTRPGAQPSIPTRAEVAASPMPPE
WSRIA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=298, Percent_Identity=33.8926174496644, Blast_Score=138, Evalue=6e-33,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=43.6666666666667, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI87082343, Length=301, Percent_Identity=30.5647840531561, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=34.3234323432343, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319884, Length=327, Percent_Identity=33.6391437308869, Blast_Score=156, Evalue=4e-39,
Organism=Drosophila melanogaster, GI20128807, Length=304, Percent_Identity=34.8684210526316, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24583886, Length=300, Percent_Identity=33, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33576; Mature: 33444

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSSRSAQENHSRSAMPRIAVVGSLNMDIVLRVPRAPGAGETVMADSLHHIPGGKGGNQ
CCCCCCCCHHHCCHHCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHCHHCCCCCCCCCH
AVACARQGARVHLLGRVGNDAHGAALRAALEADAIDHAGVQTDPEAPTGIACITVESTAQ
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCCCEEEEEEECCCC
NRIVVVGGANARFEVDARALDTALQGASNLLLQFEVPLPQVMAAARQARQRACPVVLNPS
CEEEEEECCCCEEEEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEECCC
PMQPIPDVLWPLVDTLVANEVEAALFADCDVQTPEDAAHAARLLRARGPRQVVVTLGAAG
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
AVACDGSGCRHHPGLRVDAVDTTAAGDTFLGALTVALARGESLDLAVQTGVRAAALCVTR
EEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEC
PGAQPSIPTRAEVAASPMPPEWSRIA
CCCCCCCCCCHHHCCCCCCCCHHCCC
>Mature Secondary Structure 
TVSSRSAQENHSRSAMPRIAVVGSLNMDIVLRVPRAPGAGETVMADSLHHIPGGKGGNQ
CCCCCCCHHHCCHHCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHCHHCCCCCCCCCH
AVACARQGARVHLLGRVGNDAHGAALRAALEADAIDHAGVQTDPEAPTGIACITVESTAQ
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCCCEEEEEEECCCC
NRIVVVGGANARFEVDARALDTALQGASNLLLQFEVPLPQVMAAARQARQRACPVVLNPS
CEEEEEECCCCEEEEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEECCC
PMQPIPDVLWPLVDTLVANEVEAALFADCDVQTPEDAAHAARLLRARGPRQVVVTLGAAG
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
AVACDGSGCRHHPGLRVDAVDTTAAGDTFLGALTVALARGESLDLAVQTGVRAAALCVTR
EEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEC
PGAQPSIPTRAEVAASPMPPEWSRIA
CCCCCCCCCCHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]