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The map label for this gene is lipA [H]

Identifier: 120612825

GI number: 120612825

Start: 4640666

End: 4641622

Strand: Direct

Name: lipA [H]

Synonym: Aave_4189

Alternate gene names: 120612825

Gene position: 4640666-4641622 (Clockwise)

Preceding gene: 120612820

Following gene: 120612826

Centisome position: 86.7

GC content: 71.47

Gene sequence:

>957_bases
ATGAACGGAACCCTTCGCGGCCTCGGCCGCTTCAGGGCGCTGGCGGCGCGCGCCGCCCTCGCCTTTTCCCTGGGCTGCGC
ATTCACCGTGCCGGCCGCCCATGCGCAGAGCGGCTACACCCAGACGCGCTATCCCATCGTGCTGGTGCACGGCCTGTTCG
GGTTCGACTCGGCCCTGGGCGTGGACTATTTCTACGGCATTCCCGATGCCTTGCGCAGGGACGGCGCGCAGGTGTTCGTG
GCCCAGGTGTCGGCCACCAACAGCACCGAGGTGCGCGGCGAGCAACTGCTCGCCCAGGTCAAGCAGGTGCTGGCGGTCAC
GGGCGCAGCCAAGGTGAACCTGGTCGGTCATTCCCACGGCGGCCCGACCATCCGCTACGTGGCGGGCGTGGCGCCGCAGC
TCGTGGCATCGGTCACGTCGATCGGCGGGGTGAACAAGGGCTCCCGCGTGGCGGACGTGGTGCGCGGCGTGGCGCCGCCG
GGCTCGGTGTCCGAATCGGTGGCGAGCGCCGCGGCCGGTGCGCTCGCGCAGGTGATCAGCGCGGCATCGGGCGGCTCCAG
CCTGCCGCAGAAGCCGACGGCGGCGCTCGATTCGCTCACCACGGCCGGCGCGGCGGACTTCAACCGGCGCTTTCCGCAGG
GGCTGGCCAGCGGTTGCGGCAACGGCGCCGACGTGGTGAACGGCGTGCGCTACTACTCCTGGACGGGCACGCAGCCGGTC
ACGAACGTGCTCGACCCGAGCGACGCGGGCCTGGCCCTGCTGGCGCCGGTGCATGGCGAGGCGAACGACGGGCTGGTGTC
CGCCTGCTCCTCGCGGCTGGGCCGGCACCTGGGGGACTACCGCCAGAACCACCTCGATGAAATCAACCAGATGGTGGGGC
TGCGGCACCTGTTCTCTCCCGACCCGGTGACGCTCTACCGCCAGCACGCCAACCGGCTGAAGCAGCAGGGGCTCTGA

Upstream 100 bases:

>100_bases
CCGGGTGGAACGCGGCCATGGGCGGCGAATAATGGAATTCACAAAAAAGAACGGTCGTTCTTTTTTGTGCGCATCACTAC
AACGACGGAGACAAGCAACC

Downstream 100 bases:

>100_bases
GCGATGGCGGCGGCACGCGGGCGCATGGCTGCTGCGCTGCTGGCGGCCGCGGCGCTGGGCCTGGCCGGCTGGTGGGCGCA
GCGCGCTACGGCGTACGGAG

Product: triacylglycerol lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNGTLRGLGRFRALAARAALAFSLGCAFTVPAAHAQSGYTQTRYPIVLVHGLFGFDSALGVDYFYGIPDALRRDGAQVFV
AQVSATNSTEVRGEQLLAQVKQVLAVTGAAKVNLVGHSHGGPTIRYVAGVAPQLVASVTSIGGVNKGSRVADVVRGVAPP
GSVSESVASAAAGALAQVISAASGGSSLPQKPTAALDSLTTAGAADFNRRFPQGLASGCGNGADVVNGVRYYSWTGTQPV
TNVLDPSDAGLALLAPVHGEANDGLVSACSSRLGRHLGDYRQNHLDEINQMVGLRHLFSPDPVTLYRQHANRLKQQGL

Sequences:

>Translated_318_residues
MNGTLRGLGRFRALAARAALAFSLGCAFTVPAAHAQSGYTQTRYPIVLVHGLFGFDSALGVDYFYGIPDALRRDGAQVFV
AQVSATNSTEVRGEQLLAQVKQVLAVTGAAKVNLVGHSHGGPTIRYVAGVAPQLVASVTSIGGVNKGSRVADVVRGVAPP
GSVSESVASAAAGALAQVISAASGGSSLPQKPTAALDSLTTAGAADFNRRFPQGLASGCGNGADVVNGVRYYSWTGTQPV
TNVLDPSDAGLALLAPVHGEANDGLVSACSSRLGRHLGDYRQNHLDEINQMVGLRHLFSPDPVTLYRQHANRLKQQGL
>Mature_318_residues
MNGTLRGLGRFRALAARAALAFSLGCAFTVPAAHAQSGYTQTRYPIVLVHGLFGFDSALGVDYFYGIPDALRRDGAQVFV
AQVSATNSTEVRGEQLLAQVKQVLAVTGAAKVNLVGHSHGGPTIRYVAGVAPQLVASVTSIGGVNKGSRVADVVRGVAPP
GSVSESVASAAAGALAQVISAASGGSSLPQKPTAALDSLTTAGAADFNRRFPQGLASGCGNGADVVNGVRYYSWTGTQPV
TNVLDPSDAGLALLAPVHGEANDGLVSACSSRLGRHLGDYRQNHLDEINQMVGLRHLFSPDPVTLYRQHANRLKQQGL

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Lipase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 32808; Mature: 32808

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTLRGLGRFRALAARAALAFSLGCAFTVPAAHAQSGYTQTRYPIVLVHGLFGFDSALG
CCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHCCCCCCCCCCEEEEECHHCCHHHHC
VDYFYGIPDALRRDGAQVFVAQVSATNSTEVRGEQLLAQVKQVLAVTGAAKVNLVGHSHG
CHHHHCCCHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GPTIRYVAGVAPQLVASVTSIGGVNKGSRVADVVRGVAPPGSVSESVASAAAGALAQVIS
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AASGGSSLPQKPTAALDSLTTAGAADFNRRFPQGLASGCGNGADVVNGVRYYSWTGTQPV
HCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCH
TNVLDPSDAGLALLAPVHGEANDGLVSACSSRLGRHLGDYRQNHLDEINQMVGLRHLFSP
HHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPVTLYRQHANRLKQQGL
CHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNGTLRGLGRFRALAARAALAFSLGCAFTVPAAHAQSGYTQTRYPIVLVHGLFGFDSALG
CCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHCCCCCCCCCCEEEEECHHCCHHHHC
VDYFYGIPDALRRDGAQVFVAQVSATNSTEVRGEQLLAQVKQVLAVTGAAKVNLVGHSHG
CHHHHCCCHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GPTIRYVAGVAPQLVASVTSIGGVNKGSRVADVVRGVAPPGSVSESVASAAAGALAQVIS
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AASGGSSLPQKPTAALDSLTTAGAADFNRRFPQGLASGCGNGADVVNGVRYYSWTGTQPV
HCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCH
TNVLDPSDAGLALLAPVHGEANDGLVSACSSRLGRHLGDYRQNHLDEINQMVGLRHLFSP
HHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPVTLYRQHANRLKQQGL
CHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]