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The map label for this gene is gmhB [H]

Identifier: 120612812

GI number: 120612812

Start: 4626323

End: 4626874

Strand: Reverse

Name: gmhB [H]

Synonym: Aave_4175

Alternate gene names: 120612812

Gene position: 4626874-4626323 (Counterclockwise)

Preceding gene: 120612813

Following gene: 120612811

Centisome position: 86.44

GC content: 73.73

Gene sequence:

>552_bases
ATGAAACTCGCCATTCTCGACCGCGACGGCACGCTCAATGCGTCCGGCGAGGAATTCATCTCCATGCCAGAGGAATGGGT
GCCCATGCCGGGCGTGCCCGAGGCCGTGGCGCGCCTCACCCACGCGGGATGGCGCCTGGCCGTGGCCACCAACCAGCCCG
GCCTGGGCCGCGGCCTCTTCGACGTGCTGGCGCTCAATGCCATCCACGCGCGCATGCACCGGGTGCTGGCCGCCGCCGGC
GGCCGCATCGAGGCGGTGTTCTACTGCCCCCACGCGCCCGACGAGGGGTGTGCCTGCCGCAAGCCGGCGCCGGGGCTGAT
GGAGCAGATCCGCGAGCGGTACGGCGTGGAGGGCGGCGAGATCCTCGTGGTGGGCAACTGCCCGGAGCACCTGTGGGCCG
GGACCGCCATCGGCGCACGGCTCCATGCGGTGGGCGATCCGCCCGAGGGCAGCCGTCCCTGGCCGCCCGGCGTGCAACGC
CATGCCAGCCTCGCGGATTTCGCGGACCAGCTCCTGGCCGCGGGCGAGCGCCCTCCGCCGGCCGGCGACTGA

Upstream 100 bases:

>100_bases
GGGCACGAGGGCGGTTCGGCGGCCTCTACGTCACCGGCTGGGACGCGCCGCCGACCGGCGGCACAGCGCCCGGCGGGCCG
CATCTTCCATAATCGCGCGC

Downstream 100 bases:

>100_bases
CACGTACCTGCGGCGTTGCGCACCGAACCGTACCCTGCCGCCGCTCCCGCTGAATTTTCCTTTCCTTCCTCCCGTCCATC
GCATGGCCTTCATCCGCTCC

Product: D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKLAILDRDGTLNASGEEFISMPEEWVPMPGVPEAVARLTHAGWRLAVATNQPGLGRGLFDVLALNAIHARMHRVLAAAG
GRIEAVFYCPHAPDEGCACRKPAPGLMEQIRERYGVEGGEILVVGNCPEHLWAGTAIGARLHAVGDPPEGSRPWPPGVQR
HASLADFADQLLAAGERPPPAGD

Sequences:

>Translated_183_residues
MKLAILDRDGTLNASGEEFISMPEEWVPMPGVPEAVARLTHAGWRLAVATNQPGLGRGLFDVLALNAIHARMHRVLAAAG
GRIEAVFYCPHAPDEGCACRKPAPGLMEQIRERYGVEGGEILVVGNCPEHLWAGTAIGARLHAVGDPPEGSRPWPPGVQR
HASLADFADQLLAAGERPPPAGD
>Mature_183_residues
MKLAILDRDGTLNASGEEFISMPEEWVPMPGVPEAVARLTHAGWRLAVATNQPGLGRGLFDVLALNAIHARMHRVLAAAG
GRIEAVFYCPHAPDEGCACRKPAPGLMEQIRERYGVEGGEILVVGNCPEHLWAGTAIGARLHAVGDPPEGSRPWPPGVQR
HASLADFADQLLAAGERPPPAGD

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=139, Percent_Identity=30.2158273381295, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI87082027, Length=127, Percent_Identity=29.9212598425197, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 19427; Mature: 19427

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAILDRDGTLNASGEEFISMPEEWVPMPGVPEAVARLTHAGWRLAVATNQPGLGRGLF
CEEEEECCCCCCCCCCHHHHCCCHHHCCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHH
DVLALNAIHARMHRVLAAAGGRIEAVFYCPHAPDEGCACRKPAPGLMEQIRERYGVEGGE
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
ILVVGNCPEHLWAGTAIGARLHAVGDPPEGSRPWPPGVQRHASLADFADQLLAAGERPPP
EEEECCCHHHHHCCHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
AGD
CCC
>Mature Secondary Structure
MKLAILDRDGTLNASGEEFISMPEEWVPMPGVPEAVARLTHAGWRLAVATNQPGLGRGLF
CEEEEECCCCCCCCCCHHHHCCCHHHCCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHH
DVLALNAIHARMHRVLAAAGGRIEAVFYCPHAPDEGCACRKPAPGLMEQIRERYGVEGGE
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
ILVVGNCPEHLWAGTAIGARLHAVGDPPEGSRPWPPGVQRHASLADFADQLLAAGERPPP
EEEECCCHHHHHCCHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
AGD
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 12101286 [H]