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The map label for this gene is plsC [H]

Identifier: 120612811

GI number: 120612811

Start: 4625485

End: 4626240

Strand: Reverse

Name: plsC [H]

Synonym: Aave_4174

Alternate gene names: 120612811

Gene position: 4626240-4625485 (Counterclockwise)

Preceding gene: 120612812

Following gene: 120612810

Centisome position: 86.43

GC content: 68.25

Gene sequence:

>756_bases
ATGGCCTTCATCCGCTCCGTTCTCCATCTGCTCTGGATGGCCCTCACCGTGGTGCCCTACACCCTCGCCATCCTCGTGGC
CCGGCTGTTCGGCGCGCCCACGCGCGTGCGCTACCGCATCGCGCGTGCCTGGCTCAAGCTCAGCACCGACGCGGCCCGGG
TGATCATGGGCATACGCACCCGCATCACCGGCATGGAACACCTGCCGCAGGACCCGGGGCAGGGCGTGGTGCTGCTGGTC
AAGCACCAGTCCACCTACGAAACCTTCCTGATGCCGGCGATCATGCCGCGCCCCCTGGCCTACGTGTTCAAGAAGGAACT
GCTGCAGATTCCCTTCTTCGGCTGGTCCATCGGCAGCCTGGACATGATCCACATCGACCGCGCCCAGCGGGCGCGCGCCT
TCGTCAAGGTGCTGCAGCAGGGCCGTGCGCTCCTGGCCCGCGGTACCTGGGTCATCATGTTTCCCGAGGGCACGCGCATC
GACCGCGGCCAGAAGGGCGACTACAAGAGCGGCGGCACACGCCTCGCCATCGAGGCCGGCGTGCCCGTGGTGCCGGTGGC
CGTGACTTCGGCCAAGGTCTGGCCACGCAAGGCCTTCGTCAAGCGCCCCGGCACCGTGGATGTCTCCATCGGCCGCCCCA
TTTCCCCCATCGGGCGCAAGCCCGACGAACTCATGGCCGAGGTCGAAGCCTGGATCGAAGGCGAGATGCGGCGCCTGGAT
CCGGACGCCTACGGAGCCTCCGGCACGGACCGGTGA

Upstream 100 bases:

>100_bases
CCGCCGGCCGGCGACTGACACGTACCTGCGGCGTTGCGCACCGAACCGTACCCTGCCGCCGCTCCCGCTGAATTTTCCTT
TCCTTCCTCCCGTCCATCGC

Downstream 100 bases:

>100_bases
TGCAGCGCCTGGTGCAGCTCGCACTGGATTTCTTCGGCGGGGACGGTGGTGCCGCTCCGCCGGTCCCGCCGCGCGGCATC
CTCCCCGACGCCGCGCCGCG

Product: phospholipid/glycerol acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAFIRSVLHLLWMALTVVPYTLAILVARLFGAPTRVRYRIARAWLKLSTDAARVIMGIRTRITGMEHLPQDPGQGVVLLV
KHQSTYETFLMPAIMPRPLAYVFKKELLQIPFFGWSIGSLDMIHIDRAQRARAFVKVLQQGRALLARGTWVIMFPEGTRI
DRGQKGDYKSGGTRLAIEAGVPVVPVAVTSAKVWPRKAFVKRPGTVDVSIGRPISPIGRKPDELMAEVEAWIEGEMRRLD
PDAYGASGTDR

Sequences:

>Translated_251_residues
MAFIRSVLHLLWMALTVVPYTLAILVARLFGAPTRVRYRIARAWLKLSTDAARVIMGIRTRITGMEHLPQDPGQGVVLLV
KHQSTYETFLMPAIMPRPLAYVFKKELLQIPFFGWSIGSLDMIHIDRAQRARAFVKVLQQGRALLARGTWVIMFPEGTRI
DRGQKGDYKSGGTRLAIEAGVPVVPVAVTSAKVWPRKAFVKRPGTVDVSIGRPISPIGRKPDELMAEVEAWIEGEMRRLD
PDAYGASGTDR
>Mature_250_residues
AFIRSVLHLLWMALTVVPYTLAILVARLFGAPTRVRYRIARAWLKLSTDAARVIMGIRTRITGMEHLPQDPGQGVVLLVK
HQSTYETFLMPAIMPRPLAYVFKKELLQIPFFGWSIGSLDMIHIDRAQRARAFVKVLQQGRALLARGTWVIMFPEGTRID
RGQKGDYKSGGTRLAIEAGVPVVPVAVTSAKVWPRKAFVKRPGTVDVSIGRPISPIGRKPDELMAEVEAWIEGEMRRLDP
DAYGASGTDR

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=183, Percent_Identity=29.5081967213115, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI15100175, Length=183, Percent_Identity=29.5081967213115, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789395, Length=177, Percent_Identity=33.8983050847458, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564032, Length=170, Percent_Identity=28.8235294117647, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320151, Length=231, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281364648, Length=205, Percent_Identity=25.8536585365854, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582856, Length=205, Percent_Identity=25.8536585365854, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582854, Length=205, Percent_Identity=25.8536585365854, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641614, Length=220, Percent_Identity=25, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641612, Length=220, Percent_Identity=25, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28029; Mature: 27897

Theoretical pI: Translated: 11.13; Mature: 11.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFIRSVLHLLWMALTVVPYTLAILVARLFGAPTRVRYRIARAWLKLSTDAARVIMGIRT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
RITGMEHLPQDPGQGVVLLVKHQSTYETFLMPAIMPRPLAYVFKKELLQIPFFGWSIGSL
HHCCHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCE
DMIHIDRAQRARAFVKVLQQGRALLARGTWVIMFPEGTRIDRGQKGDYKSGGTRLAIEAG
EEEEECHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECC
VPVVPVAVTSAKVWPRKAFVKRPGTVDVSIGRPISPIGRKPDELMAEVEAWIEGEMRRLD
CCEEEEEECCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHCC
PDAYGASGTDR
CCCCCCCCCCC
>Mature Secondary Structure 
AFIRSVLHLLWMALTVVPYTLAILVARLFGAPTRVRYRIARAWLKLSTDAARVIMGIRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
RITGMEHLPQDPGQGVVLLVKHQSTYETFLMPAIMPRPLAYVFKKELLQIPFFGWSIGSL
HHCCHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCE
DMIHIDRAQRARAFVKVLQQGRALLARGTWVIMFPEGTRIDRGQKGDYKSGGTRLAIEAG
EEEEECHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECC
VPVVPVAVTSAKVWPRKAFVKRPGTVDVSIGRPISPIGRKPDELMAEVEAWIEGEMRRLD
CCEEEEEECCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHCC
PDAYGASGTDR
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]