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The map label for this gene is abcA [H]

Identifier: 120612782

GI number: 120612782

Start: 4597855

End: 4599144

Strand: Reverse

Name: abcA [H]

Synonym: Aave_4145

Alternate gene names: 120612782

Gene position: 4599144-4597855 (Counterclockwise)

Preceding gene: 120612783

Following gene: 120612781

Centisome position: 85.92

GC content: 64.11

Gene sequence:

>1290_bases
ATGAGCCCGCTGCAGACATCGTCCGAGACAGTGCTGCAGGTGAAGAATCTGGGCAAGGAGTACCGCATCTATGCGTCTCC
CCGCCAGCGCCTCAAGTCGCTCATCACCGGCCGTTCCCACCACCGCAGCCACTGGGCGCTGAAGGATGTGTCCTTCGAAT
TGCGGCGTGGCCAGTGTATCGGCGTGATTGGTGACAATGGTGCCGGCAAGAGTTCGCTGCTGAAACTGCTGGCCGGAACG
CTTCAGCCATCGACCGGTTCGATCGAGCGCGTAGGGCGGGTGACGGCCATTCTGGAGCTCGGTGCCGGCTTCCATCCGGA
CTTCAGCGGACGGGACAATCTGTACTTCGGCGGCAGCCTGATAGGCATCGACCGGGAGACGATGCAGCGGCTGGAGCCCG
AAATCATCGAGTTCAGTGAGCTTGGCCATGCGCTGGACCGGCCCGTGAAGACCTACTCCTCGGGCATGGCAGTGCGCCTC
GCGTTTGCGCTGGTCACGGCAGTGCAGCCTGACGTGCTCATCATCGACGAGGCGCTGGCGGTGGGAGACCAGCATTTCCA
GAAGAAATGCGTGGATCGCATCATGGCCTTCCGCGATGCAGGCTGCACCATCCTGTTCTGCTCCCACAGTCCCTATCACA
TACGGCATCTGTGCGACGTGGCCTTGTGGCTGAAGGATGGCTGCGTGGAGCAGTTCGGGCCGACGGAGCCCGTGCTGGCC
GCCTACGATCTGCACACCCGGCTGCGTGACGGCCAGCCCCAGGAGATGCTCCCACAGGGGGCGGAGCCTGCCCCGTCTCT
GGCGCCGCCCGGCGAATCAATGCCCTCCGTTGCCGGAGAGGGCCATGCGCGGCGGGAACGCGCCGCTGGCGGAGACTCCG
GCAGTGCCTGTATCGTTTCCGTGGATGTCAAGGATCTCGCCGAGCCGCAGGGCGAGCGGCCCGGTACGTTGCGGAGCAGC
GACCTGGTGGTGTCCATTGTGGTGCGTGGGCGCGGGGACGAGCGTCCGAACATCGGCTTCATGATCGAGCAGTCCCGAGG
CGTGGGCATCACCTCGCTGGGCACCCATGAAGAGGGCGCGGAGCCGGTCCGGCTGGAGGACGGCTCCTGGCGGTCGGTCC
TGACCTTCCCCGAGTTGCCGCTCCATACGGGCGACTACGTCATCAGTGTCTATCTCTTCGACGAGACGGGACTGGTGGTG
TATGACGAATGGTTCCAGTTCCTGCATTTCCATTTTTCTTTTCCAAAGCCCATGCCGGGCCTTGTCCGTCTGCCGCACCG
CTGGGAATGA

Upstream 100 bases:

>100_bases
CGGCGGGTGTCTGGCTGGCGGGCGCTGCATGGCTCGTGGTGGTGGCCATGGCTTTGAATGTGGTTGTCCGGCGCAGCCGC
GACCAACTGGTGGATTGGCT

Downstream 100 bases:

>100_bases
GTTGGTGACTACACGTTGGGCCCGCGCCTGGTCGCGGTGGAAAAGGGAAAGCCGGGATGTGCTGGAGGTGGTGCTGCTGC
CGGGGCTCGCGGCCGTGCTG

Product: ABC transporter-like protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSPLQTSSETVLQVKNLGKEYRIYASPRQRLKSLITGRSHHRSHWALKDVSFELRRGQCIGVIGDNGAGKSSLLKLLAGT
LQPSTGSIERVGRVTAILELGAGFHPDFSGRDNLYFGGSLIGIDRETMQRLEPEIIEFSELGHALDRPVKTYSSGMAVRL
AFALVTAVQPDVLIIDEALAVGDQHFQKKCVDRIMAFRDAGCTILFCSHSPYHIRHLCDVALWLKDGCVEQFGPTEPVLA
AYDLHTRLRDGQPQEMLPQGAEPAPSLAPPGESMPSVAGEGHARRERAAGGDSGSACIVSVDVKDLAEPQGERPGTLRSS
DLVVSIVVRGRGDERPNIGFMIEQSRGVGITSLGTHEEGAEPVRLEDGSWRSVLTFPELPLHTGDYVISVYLFDETGLVV
YDEWFQFLHFHFSFPKPMPGLVRLPHRWE

Sequences:

>Translated_429_residues
MSPLQTSSETVLQVKNLGKEYRIYASPRQRLKSLITGRSHHRSHWALKDVSFELRRGQCIGVIGDNGAGKSSLLKLLAGT
LQPSTGSIERVGRVTAILELGAGFHPDFSGRDNLYFGGSLIGIDRETMQRLEPEIIEFSELGHALDRPVKTYSSGMAVRL
AFALVTAVQPDVLIIDEALAVGDQHFQKKCVDRIMAFRDAGCTILFCSHSPYHIRHLCDVALWLKDGCVEQFGPTEPVLA
AYDLHTRLRDGQPQEMLPQGAEPAPSLAPPGESMPSVAGEGHARRERAAGGDSGSACIVSVDVKDLAEPQGERPGTLRSS
DLVVSIVVRGRGDERPNIGFMIEQSRGVGITSLGTHEEGAEPVRLEDGSWRSVLTFPELPLHTGDYVISVYLFDETGLVV
YDEWFQFLHFHFSFPKPMPGLVRLPHRWE
>Mature_428_residues
SPLQTSSETVLQVKNLGKEYRIYASPRQRLKSLITGRSHHRSHWALKDVSFELRRGQCIGVIGDNGAGKSSLLKLLAGTL
QPSTGSIERVGRVTAILELGAGFHPDFSGRDNLYFGGSLIGIDRETMQRLEPEIIEFSELGHALDRPVKTYSSGMAVRLA
FALVTAVQPDVLIIDEALAVGDQHFQKKCVDRIMAFRDAGCTILFCSHSPYHIRHLCDVALWLKDGCVEQFGPTEPVLAA
YDLHTRLRDGQPQEMLPQGAEPAPSLAPPGESMPSVAGEGHARRERAAGGDSGSACIVSVDVKDLAEPQGERPGTLRSSD
LVVSIVVRGRGDERPNIGFMIEQSRGVGITSLGTHEEGAEPVRLEDGSWRSVLTFPELPLHTGDYVISVYLFDETGLVVY
DEWFQFLHFHFSFPKPMPGLVRLPHRWE

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI31657092, Length=223, Percent_Identity=29.1479820627803, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI6005701, Length=189, Percent_Identity=27.5132275132275, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI27477115, Length=245, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI153792144, Length=242, Percent_Identity=23.9669421487603, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI27436953, Length=187, Percent_Identity=24.5989304812834, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI27881501, Length=191, Percent_Identity=26.1780104712042, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI30795238, Length=191, Percent_Identity=26.1780104712042, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787547, Length=274, Percent_Identity=29.1970802919708, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790467, Length=197, Percent_Identity=27.4111675126904, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI48995001, Length=200, Percent_Identity=28.5, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081709, Length=202, Percent_Identity=24.7524752475248, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789032, Length=256, Percent_Identity=25, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787712, Length=232, Percent_Identity=25, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788210, Length=199, Percent_Identity=29.6482412060301, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788165, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788761, Length=201, Percent_Identity=23.8805970149254, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787792, Length=303, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786563, Length=174, Percent_Identity=28.735632183908, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789751, Length=253, Percent_Identity=27.6679841897233, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081782, Length=132, Percent_Identity=30.3030303030303, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=189, Percent_Identity=29.1005291005291, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17569081, Length=205, Percent_Identity=24.8780487804878, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146765, Length=208, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71992066, Length=208, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71992070, Length=208, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86564969, Length=208, Percent_Identity=25, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=257, Percent_Identity=23.7354085603113, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007184, Length=191, Percent_Identity=29.8429319371728, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221500365, Length=191, Percent_Identity=29.8429319371728, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573571, Length=262, Percent_Identity=25.5725190839695, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28573573, Length=262, Percent_Identity=25.5725190839695, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221512771, Length=208, Percent_Identity=28.3653846153846, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24643674, Length=219, Percent_Identity=23.7442922374429, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 47198; Mature: 47067

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLQTSSETVLQVKNLGKEYRIYASPRQRLKSLITGRSHHRSHWALKDVSFELRRGQCI
CCCCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCCCCEEEHHCCCEECCCCEE
GVIGDNGAGKSSLLKLLAGTLQPSTGSIERVGRVTAILELGAGFHPDFSGRDNLYFGGSL
EEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCEE
IGIDRETMQRLEPEIIEFSELGHALDRPVKTYSSGMAVRLAFALVTAVQPDVLIIDEALA
EECCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCCEEEEEHHHH
VGDQHFQKKCVDRIMAFRDAGCTILFCSHSPYHIRHLCDVALWLKDGCVEQFGPTEPVLA
HCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEE
AYDLHTRLRDGQPQEMLPQGAEPAPSLAPPGESMPSVAGEGHARRERAAGGDSGSACIVS
HHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEE
VDVKDLAEPQGERPGTLRSSDLVVSIVVRGRGDERPNIGFMIEQSRGVGITSLGTHEEGA
ECHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEECCCCCCEEECCCCCCCC
EPVRLEDGSWRSVLTFPELPLHTGDYVISVYLFDETGLVVYDEWFQFLHFHFSFPKPMPG
CCEEECCCCCCEEEECCCCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCH
LVRLPHRWE
HHCCCCCCC
>Mature Secondary Structure 
SPLQTSSETVLQVKNLGKEYRIYASPRQRLKSLITGRSHHRSHWALKDVSFELRRGQCI
CCCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCCCCEEEHHCCCEECCCCEE
GVIGDNGAGKSSLLKLLAGTLQPSTGSIERVGRVTAILELGAGFHPDFSGRDNLYFGGSL
EEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCEE
IGIDRETMQRLEPEIIEFSELGHALDRPVKTYSSGMAVRLAFALVTAVQPDVLIIDEALA
EECCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCCEEEEEHHHH
VGDQHFQKKCVDRIMAFRDAGCTILFCSHSPYHIRHLCDVALWLKDGCVEQFGPTEPVLA
HCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEE
AYDLHTRLRDGQPQEMLPQGAEPAPSLAPPGESMPSVAGEGHARRERAAGGDSGSACIVS
HHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEE
VDVKDLAEPQGERPGTLRSSDLVVSIVVRGRGDERPNIGFMIEQSRGVGITSLGTHEEGA
ECHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEECCCCCCEEECCCCCCCC
EPVRLEDGSWRSVLTFPELPLHTGDYVISVYLFDETGLVVYDEWFQFLHFHFSFPKPMPG
CCEEECCCCCCEEEECCCCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCH
LVRLPHRWE
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]