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The map label for this gene is qseB [H]

Identifier: 120612775

GI number: 120612775

Start: 4588371

End: 4589090

Strand: Reverse

Name: qseB [H]

Synonym: Aave_4138

Alternate gene names: 120612775

Gene position: 4589090-4588371 (Counterclockwise)

Preceding gene: 120612776

Following gene: 120612774

Centisome position: 85.73

GC content: 69.72

Gene sequence:

>720_bases
ATGCGCCTGCTGCTCGTCGAAGACGACGTGATGCTGGCCAGCGGCATCAAGCTGGGCCTCACCGACGCGGGCTACGCGGT
GGACTGGGTCGGCAGTGGGGAGCGGGCGGAAGAGGTGCTGCGCGGCGAGACGTTCGATGCCGCCATCATCGATATCGGAC
TGCCGGGCATGGACGGCCTGGAGCTGACGCGCCGCCTGCGCGAGCCGGAGATGGCCAGCCCATCCATGCCGGTGCTCATC
CTCACGGCGCGCGATGCCCTGCACGATCGGGTCCAGGGGCTGGACCTCGGGGCGGACGATTACATGGTCAAGCCCTATGA
GCTGCCCGAACTGCTCGCACGCCTTCGCGCGTTGCTGCGCCGCTCGCATGCCGCGACCACCGCGGTGCTGAGCTTCGGGC
CGCTGGAACTGGATACGGCAGGGCGGCACGCGACCCTGCGTGTCCCGGCCACCGGCGATGCGCCGGCGCTGCGCCAGCCC
ATCGAACTCGGCCCGAGGGAGTGGACGGTGCTGGAGTACCTGCTGATCCACGCACCCAAGCCGGCCAGCAAGGAAAAGCT
GGTCCAGGCGCTGACCGGCTGGGACAAGGAGATCACGCCCAATGCCGTGGAGGTGTATGTGTCCCGCCTGCGTGGCAAGC
TGGAGCCCGGTGGCGTGGCCCTGCGCTCCATCCGCGGCTTCGGCTACCGGCTGGAGTTGCTGGCGCCTGCGCAGGGCTGA

Upstream 100 bases:

>100_bases
CGCGTGCCCCACGCGATGCTGCTGGAGATCCTGACCGAGCAGGCCTACGGCACGATGATCCGCAGCCATTGAGCGCGGCG
GCGGGCCTGCTGTTCCTTCC

Downstream 100 bases:

>100_bases
CGACCACGGCTGGCGCGGCCCCGCCCCCACGGAGGAGGTCTGGTGCGATGACATCGGTGCTGCGCAACCGTCTGCTGTTC
TTTCTCGTGCTGCCGCTGTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MRLLLVEDDVMLASGIKLGLTDAGYAVDWVGSGERAEEVLRGETFDAAIIDIGLPGMDGLELTRRLREPEMASPSMPVLI
LTARDALHDRVQGLDLGADDYMVKPYELPELLARLRALLRRSHAATTAVLSFGPLELDTAGRHATLRVPATGDAPALRQP
IELGPREWTVLEYLLIHAPKPASKEKLVQALTGWDKEITPNAVEVYVSRLRGKLEPGGVALRSIRGFGYRLELLAPAQG

Sequences:

>Translated_239_residues
MRLLLVEDDVMLASGIKLGLTDAGYAVDWVGSGERAEEVLRGETFDAAIIDIGLPGMDGLELTRRLREPEMASPSMPVLI
LTARDALHDRVQGLDLGADDYMVKPYELPELLARLRALLRRSHAATTAVLSFGPLELDTAGRHATLRVPATGDAPALRQP
IELGPREWTVLEYLLIHAPKPASKEKLVQALTGWDKEITPNAVEVYVSRLRGKLEPGGVALRSIRGFGYRLELLAPAQG
>Mature_239_residues
MRLLLVEDDVMLASGIKLGLTDAGYAVDWVGSGERAEEVLRGETFDAAIIDIGLPGMDGLELTRRLREPEMASPSMPVLI
LTARDALHDRVQGLDLGADDYMVKPYELPELLARLRALLRRSHAATTAVLSFGPLELDTAGRHATLRVPATGDAPALRQP
IELGPREWTVLEYLLIHAPKPASKEKLVQALTGWDKEITPNAVEVYVSRLRGKLEPGGVALRSIRGFGYRLELLAPAQG

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=44.1558441558442, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=39.8268398268398, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1787375, Length=237, Percent_Identity=35.4430379746835, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786784, Length=238, Percent_Identity=35.7142857142857, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789809, Length=238, Percent_Identity=33.6134453781513, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=34.1880341880342, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=32.618025751073, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=31.4655172413793, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=34.7457627118644, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786911, Length=243, Percent_Identity=33.7448559670782, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=30.0847457627119, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787229, Length=215, Percent_Identity=31.6279069767442, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790863, Length=245, Percent_Identity=30.2040816326531, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790437, Length=196, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI145693140, Length=249, Percent_Identity=28.1124497991968, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788713, Length=102, Percent_Identity=36.2745098039216, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26060; Mature: 26060

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLVEDDVMLASGIKLGLTDAGYAVDWVGSGERAEEVLRGETFDAAIIDIGLPGMDGL
CEEEEEECCEEEECCCEEEECCCCCEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCHH
ELTRRLREPEMASPSMPVLILTARDALHDRVQGLDLGADDYMVKPYELPELLARLRALLR
HHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHH
RSHAATTAVLSFGPLELDTAGRHATLRVPATGDAPALRQPIELGPREWTVLEYLLIHAPK
HHHHHHHHEEECCCEEECCCCCEEEEEECCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCC
PASKEKLVQALTGWDKEITPNAVEVYVSRLRGKLEPGGVALRSIRGFGYRLELLAPAQG
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEECCCC
>Mature Secondary Structure
MRLLLVEDDVMLASGIKLGLTDAGYAVDWVGSGERAEEVLRGETFDAAIIDIGLPGMDGL
CEEEEEECCEEEECCCEEEECCCCCEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCHH
ELTRRLREPEMASPSMPVLILTARDALHDRVQGLDLGADDYMVKPYELPELLARLRALLR
HHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHH
RSHAATTAVLSFGPLELDTAGRHATLRVPATGDAPALRQPIELGPREWTVLEYLLIHAPK
HHHHHHHHEEECCCEEECCCCCEEEEEECCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCC
PASKEKLVQALTGWDKEITPNAVEVYVSRLRGKLEPGGVALRSIRGFGYRLELLAPAQG
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]