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The map label for this gene is qseC [H]

Identifier: 120612774

GI number: 120612774

Start: 4586908

End: 4588323

Strand: Reverse

Name: qseC [H]

Synonym: Aave_4137

Alternate gene names: 120612774

Gene position: 4588323-4586908 (Counterclockwise)

Preceding gene: 120612775

Following gene: 120612773

Centisome position: 85.72

GC content: 70.62

Gene sequence:

>1416_bases
ATGACATCGGTGCTGCGCAACCGTCTGCTGTTCTTTCTCGTGCTGCCGCTGTGCGTTCTCGCATTGGCAGGGGCCTGGCT
GGACTACCGCTCCGCGGACGAGGCCGCCAGCCGGCACGACCAGCGCCTCGTGCGGCTGCTGCCGGCGCTCGCCGATTCGG
TGGCCGCACCGTCCCGGCGCGAGGGGGAACCCCCCGTACTCCTGCTGGCGCCACCCGTCGAGGAGTTCCTGCGGCAGAAC
GCCGGCTATGCGGGCTACAGCGTGCAGGATCTTTCGGGCCGCATCCTGCTCGGCGACCACTGGGTGTACAGCGCGGTGCC
GCTCACGCATGAGCCGGAGCTCCACAGCGTGGAGCATGACAGTGTCATCTATCGCGTCGCCGTGCAGCGCACCCGTACCG
GGGCGGGTGAACTGGTGGTCGCGCTGGCCGACGGGTCGGATCGCCGCCAGCAGTGGGGACAGCAGATGCTGCTGCGGGTG
TTGCTGCCCAACCTCGTGCTGGTCGCGGCGGCAGGGTTGGCGATCCATTGGGCGGTGCGCCAGGCTTTCAAGCCTCTGGT
GGATCTGGCCGAGGCCGTCGAGCACCGTTCGCCGCGCGACCTGAGCCCCATACCGGAAGAGGCTTCGCCCGCCGAAGTGC
GCCCGCTGGTGCGCTCGCTCAACCGGCTCTTCGTTCTGGTCAATGCGCAGACCGAGGGGCAGCGCCGTTTCGTCGCGGAT
GCGGCCCACCAGCTGCGAACGCCGCTGGCGGGCCTGCAGGCCCAGGTGGAGGCGTGGGCGCTGGCCGCCCGGGCCGCGGA
CCATGGCCGGGCCGGGGATGGACTGGTGCAGGGAGGCATTGTCCTGGGCGTGCAGGACATCGAGGCGCTACGCAAAGCGG
CGCGCCGCACCTCCAAGCTCGCGCACCAGTTGCTGGCCCTGTCCCGTGCCGATGCGGGCAGCGTGGATGCCCAGCCCAAG
CACCGCGTGGATCTCAAGGCGCTTTGCGAGAGCCTGCTGGAGGATTTCCTGGACGCAGCCACCGCCCGCGGGCTGGATCT
GGGGCTGGAGGTGGAGCCGGCCGGAGTGCCCGGCCACGGATGGCTGTTGCGAGAGCTGCTTTCCAACCTCGTGGACAACG
CCATCCGGTACACGGCGGAGGGAGGCAGTGTCACCTTGCGATGCGGGATGCGGTCCGGTGGCAGCGAAGCGTGCTGCGCG
ATCCTGGAAGTGGAGGACGACGGCCCCGGCATCGCCGAATCGGAGCGCAACAAGGTGCTGCAGCGGTTCTACCGGGTTCC
GGGCGCTGCGGGGGAGGGGACCGGCCTGGGGCTGGCGATCGCCGACGAGATCGCGCGCGGGCACGGCGGGACGCTGCAGT
TGCGCCCGGGACGCCTGGGCCGGGGGCTGCGTGCCAGCGTTTCCCTTCCGGCATAG

Upstream 100 bases:

>100_bases
CCATCCGCGGCTTCGGCTACCGGCTGGAGTTGCTGGCGCCTGCGCAGGGCTGACGACCACGGCTGGCGCGGCCCCGCCCC
CACGGAGGAGGTCTGGTGCG

Downstream 100 bases:

>100_bases
GTGCGTGGAGCGCGAGCCGGCGGTCATCGTGCGGCAGAGGCGGTATGCGAGAATCAATTGCATACATTTGCGGCCATGGC
TGAATCCTTTTCCCATCCCA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTSVLRNRLLFFLVLPLCVLALAGAWLDYRSADEAASRHDQRLVRLLPALADSVAAPSRREGEPPVLLLAPPVEEFLRQN
AGYAGYSVQDLSGRILLGDHWVYSAVPLTHEPELHSVEHDSVIYRVAVQRTRTGAGELVVALADGSDRRQQWGQQMLLRV
LLPNLVLVAAAGLAIHWAVRQAFKPLVDLAEAVEHRSPRDLSPIPEEASPAEVRPLVRSLNRLFVLVNAQTEGQRRFVAD
AAHQLRTPLAGLQAQVEAWALAARAADHGRAGDGLVQGGIVLGVQDIEALRKAARRTSKLAHQLLALSRADAGSVDAQPK
HRVDLKALCESLLEDFLDAATARGLDLGLEVEPAGVPGHGWLLRELLSNLVDNAIRYTAEGGSVTLRCGMRSGGSEACCA
ILEVEDDGPGIAESERNKVLQRFYRVPGAAGEGTGLGLAIADEIARGHGGTLQLRPGRLGRGLRASVSLPA

Sequences:

>Translated_471_residues
MTSVLRNRLLFFLVLPLCVLALAGAWLDYRSADEAASRHDQRLVRLLPALADSVAAPSRREGEPPVLLLAPPVEEFLRQN
AGYAGYSVQDLSGRILLGDHWVYSAVPLTHEPELHSVEHDSVIYRVAVQRTRTGAGELVVALADGSDRRQQWGQQMLLRV
LLPNLVLVAAAGLAIHWAVRQAFKPLVDLAEAVEHRSPRDLSPIPEEASPAEVRPLVRSLNRLFVLVNAQTEGQRRFVAD
AAHQLRTPLAGLQAQVEAWALAARAADHGRAGDGLVQGGIVLGVQDIEALRKAARRTSKLAHQLLALSRADAGSVDAQPK
HRVDLKALCESLLEDFLDAATARGLDLGLEVEPAGVPGHGWLLRELLSNLVDNAIRYTAEGGSVTLRCGMRSGGSEACCA
ILEVEDDGPGIAESERNKVLQRFYRVPGAAGEGTGLGLAIADEIARGHGGTLQLRPGRLGRGLRASVSLPA
>Mature_470_residues
TSVLRNRLLFFLVLPLCVLALAGAWLDYRSADEAASRHDQRLVRLLPALADSVAAPSRREGEPPVLLLAPPVEEFLRQNA
GYAGYSVQDLSGRILLGDHWVYSAVPLTHEPELHSVEHDSVIYRVAVQRTRTGAGELVVALADGSDRRQQWGQQMLLRVL
LPNLVLVAAAGLAIHWAVRQAFKPLVDLAEAVEHRSPRDLSPIPEEASPAEVRPLVRSLNRLFVLVNAQTEGQRRFVADA
AHQLRTPLAGLQAQVEAWALAARAADHGRAGDGLVQGGIVLGVQDIEALRKAARRTSKLAHQLLALSRADAGSVDAQPKH
RVDLKALCESLLEDFLDAATARGLDLGLEVEPAGVPGHGWLLRELLSNLVDNAIRYTAEGGSVTLRCGMRSGGSEACCAI
LEVEDDGPGIAESERNKVLQRFYRVPGAAGEGTGLGLAIADEIARGHGGTLQLRPGRLGRGLRASVSLPA

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=311, Percent_Identity=32.475884244373, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790551, Length=315, Percent_Identity=29.2063492063492, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1786783, Length=329, Percent_Identity=26.4437689969605, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788393, Length=291, Percent_Identity=29.2096219931272, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=249, Percent_Identity=30.9236947791165, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788279, Length=344, Percent_Identity=25.5813953488372, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790346, Length=293, Percent_Identity=27.9863481228669, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=331, Percent_Identity=27.190332326284, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789808, Length=294, Percent_Identity=27.2108843537415, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=304, Percent_Identity=27.6315789473684, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=260, Percent_Identity=27.3076923076923, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=22.8, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081816, Length=325, Percent_Identity=26.7692307692308, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=23.109243697479, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=27.3127753303965, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=26.027397260274, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50581; Mature: 50449

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVLRNRLLFFLVLPLCVLALAGAWLDYRSADEAASRHDQRLVRLLPALADSVAAPSRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGEPPVLLLAPPVEEFLRQNAGYAGYSVQDLSGRILLGDHWVYSAVPLTHEPELHSVEHD
CCCCCEEEECCCHHHHHHCCCCCCCCEEECCCCEEEEECCEEEEECCCCCCCCCCCCCCC
SVIYRVAVQRTRTGAGELVVALADGSDRRQQWGQQMLLRVLLPNLVLVAAAGLAIHWAVR
HHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAFKPLVDLAEAVEHRSPRDLSPIPEEASPAEVRPLVRSLNRLFVLVNAQTEGQRRFVAD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHHH
AAHQLRTPLAGLQAQVEAWALAARAADHGRAGDGLVQGGIVLGVQDIEALRKAARRTSKL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEHHHHHHHHHHHHHHHHH
AHQLLALSRADAGSVDAQPKHRVDLKALCESLLEDFLDAATARGLDLGLEVEPAGVPGHG
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHH
WLLRELLSNLVDNAIRYTAEGGSVTLRCGMRSGGSEACCAILEVEDDGPGIAESERNKVL
HHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHHH
QRFYRVPGAAGEGTGLGLAIADEIARGHGGTLQLRPGRLGRGLRASVSLPA
HHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSVLRNRLLFFLVLPLCVLALAGAWLDYRSADEAASRHDQRLVRLLPALADSVAAPSRR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGEPPVLLLAPPVEEFLRQNAGYAGYSVQDLSGRILLGDHWVYSAVPLTHEPELHSVEHD
CCCCCEEEECCCHHHHHHCCCCCCCCEEECCCCEEEEECCEEEEECCCCCCCCCCCCCCC
SVIYRVAVQRTRTGAGELVVALADGSDRRQQWGQQMLLRVLLPNLVLVAAAGLAIHWAVR
HHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAFKPLVDLAEAVEHRSPRDLSPIPEEASPAEVRPLVRSLNRLFVLVNAQTEGQRRFVAD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHHH
AAHQLRTPLAGLQAQVEAWALAARAADHGRAGDGLVQGGIVLGVQDIEALRKAARRTSKL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEHHHHHHHHHHHHHHHHH
AHQLLALSRADAGSVDAQPKHRVDLKALCESLLEDFLDAATARGLDLGLEVEPAGVPGHG
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHH
WLLRELLSNLVDNAIRYTAEGGSVTLRCGMRSGGSEACCAILEVEDDGPGIAESERNKVL
HHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHHH
QRFYRVPGAAGEGTGLGLAIADEIARGHGGTLQLRPGRLGRGLRASVSLPA
HHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]