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The map label for this gene is tlyA [H]

Identifier: 120612696

GI number: 120612696

Start: 4509070

End: 4510071

Strand: Reverse

Name: tlyA [H]

Synonym: Aave_4059

Alternate gene names: 120612696

Gene position: 4510071-4509070 (Counterclockwise)

Preceding gene: 120612697

Following gene: 120612695

Centisome position: 84.26

GC content: 70.36

Gene sequence:

>1002_bases
ATGCGCGCGGATGTGTTTTTGGTGGAGCGCGGCCATGCCGCCACACGGTCGCAGGCGCAGCGCCTGATCGCGGCCGGTGT
GCAGTGGCGCCTGGCGGCCGGCATGGCGTGGACGAAGGTGGCGAAGAACGGCGACGACATCCCGGCGATCGCCGAGGTCG
AGTTGCTGGACGGGGCCGAGGCCCGGTATCTGTCGCGCGGCGGGCTCAAGCTGGAAGGGGCGCTGCAGGCCACCGGGTTG
TCGGTGGCCGGGCGGCGCTGCCTGGACGTGGGGCAGAGCACGGGCGGTTTCACCGATTGCCTGCTGCAGCACGGCGCGGC
GCAGGTGATCGGCGTGGACGTGGGCCATGGACAACTGCACGAGCGGCTGCGCGATGATCCGCGCGTGGTGGGCGTGGAAG
GGCTGAACGCCCGCTCCATGACCGCCGAGTCGCTGCAGGAGGCCTGCGAAGAGGCATTGTCCGAACGCGTCGAACGCGAC
GTGGAGGACAACGAGACCCAGCCCGTGGCGCCCTATGCGTGGATGCGAAACGGCGGCCAGGTGGACGACGAGTACGACGA
CAGCGACGATGCCAAGGAGCACGAGGTGGAGGCCTTCAAGGCCGAGCGCGAGGCCAGGGCGCGCGCGCGTGCCGAGGGTG
CGCTGCCCACCGAGCTGCGCCGCCGTGCGGGACGCGAGGACGTGGACATCACGCCCGAATTCGATCTCGTCACCGGCGAT
GTGTCCTTCATCTCGCTCACGCTGATCCTGCCGGCCGTGGTGCCGCTGCTCAAGGCGGACGGCGAGCTGCTGATGCTGGT
CAAGCCGCAGTTCGAGCTGCAGCCGGGGCAGGTGGGCAAGGGCGGCATCGTGCGCGACCCGGCCCTGTATGCCCAGGTGG
AGCAGCGCCTGCGCGAATGCTGCGCCGCGGCGGGCCTGGACGTGGCCGGGTGGCACGACAGCCCGATCGACGGCGGCGAC
GGCAACCGCGAATTCTTCATCCACGCAAGGAGGAAGGCATGA

Upstream 100 bases:

>100_bases
GTGCGGCAACGTCGCCGGCACAATTCTCTCAGCCGCGCTGCAATGGATTGAAATGTGGCGGGCCGCGTGTGCGGCCGGCC
CTGTTGGAGAGGAAGGCGCC

Downstream 100 bases:

>100_bases
GCCTTTCCACGCACGAGGCGGCCCTTCCGGTCAGCTTCGAATTCTTCCCTCCCAAGACGCCCGAGGGCGCGGACAAGCTG
CGCACCGTGCGCCAGCAGCT

Product: ribosomal RNA methyltransferase RrmJ/FtsJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRADVFLVERGHAATRSQAQRLIAAGVQWRLAAGMAWTKVAKNGDDIPAIAEVELLDGAEARYLSRGGLKLEGALQATGL
SVAGRRCLDVGQSTGGFTDCLLQHGAAQVIGVDVGHGQLHERLRDDPRVVGVEGLNARSMTAESLQEACEEALSERVERD
VEDNETQPVAPYAWMRNGGQVDDEYDDSDDAKEHEVEAFKAEREARARARAEGALPTELRRRAGREDVDITPEFDLVTGD
VSFISLTLILPAVVPLLKADGELLMLVKPQFELQPGQVGKGGIVRDPALYAQVEQRLRECCAAAGLDVAGWHDSPIDGGD
GNREFFIHARRKA

Sequences:

>Translated_333_residues
MRADVFLVERGHAATRSQAQRLIAAGVQWRLAAGMAWTKVAKNGDDIPAIAEVELLDGAEARYLSRGGLKLEGALQATGL
SVAGRRCLDVGQSTGGFTDCLLQHGAAQVIGVDVGHGQLHERLRDDPRVVGVEGLNARSMTAESLQEACEEALSERVERD
VEDNETQPVAPYAWMRNGGQVDDEYDDSDDAKEHEVEAFKAEREARARARAEGALPTELRRRAGREDVDITPEFDLVTGD
VSFISLTLILPAVVPLLKADGELLMLVKPQFELQPGQVGKGGIVRDPALYAQVEQRLRECCAAAGLDVAGWHDSPIDGGD
GNREFFIHARRKA
>Mature_333_residues
MRADVFLVERGHAATRSQAQRLIAAGVQWRLAAGMAWTKVAKNGDDIPAIAEVELLDGAEARYLSRGGLKLEGALQATGL
SVAGRRCLDVGQSTGGFTDCLLQHGAAQVIGVDVGHGQLHERLRDDPRVVGVEGLNARSMTAESLQEACEEALSERVERD
VEDNETQPVAPYAWMRNGGQVDDEYDDSDDAKEHEVEAFKAEREARARARAEGALPTELRRRAGREDVDITPEFDLVTGD
VSFISLTLILPAVVPLLKADGELLMLVKPQFELQPGQVGKGGIVRDPALYAQVEQRLRECCAAAGLDVAGWHDSPIDGGD
GNREFFIHARRKA

Specific function: Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined [H]

COG id: COG1189

COG function: function code J; Predicted rRNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004538
- InterPro:   IPR002877
- InterPro:   IPR002942 [H]

Pfam domain/function: PF01728 FtsJ; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 36110; Mature: 36110

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRADVFLVERGHAATRSQAQRLIAAGVQWRLAAGMAWTKVAKNGDDIPAIAEVELLDGAE
CCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCCH
ARYLSRGGLKLEGALQATGLSVAGRRCLDVGQSTGGFTDCLLQHGAAQVIGVDVGHGQLH
HHHHHCCCEEEECCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCCHHHH
ERLRDDPRVVGVEGLNARSMTAESLQEACEEALSERVERDVEDNETQPVAPYAWMRNGGQ
HHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCC
VDDEYDDSDDAKEHEVEAFKAEREARARARAEGALPTELRRRAGREDVDITPEFDLVTGD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEECC
VSFISLTLILPAVVPLLKADGELLMLVKPQFELQPGQVGKGGIVRDPALYAQVEQRLREC
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
CAAAGLDVAGWHDSPIDGGDGNREFFIHARRKA
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MRADVFLVERGHAATRSQAQRLIAAGVQWRLAAGMAWTKVAKNGDDIPAIAEVELLDGAE
CCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCCH
ARYLSRGGLKLEGALQATGLSVAGRRCLDVGQSTGGFTDCLLQHGAAQVIGVDVGHGQLH
HHHHHCCCEEEECCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCCHHHH
ERLRDDPRVVGVEGLNARSMTAESLQEACEEALSERVERDVEDNETQPVAPYAWMRNGGQ
HHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCC
VDDEYDDSDDAKEHEVEAFKAEREARARARAEGALPTELRRRAGREDVDITPEFDLVTGD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEECC
VSFISLTLILPAVVPLLKADGELLMLVKPQFELQPGQVGKGGIVRDPALYAQVEQRLREC
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
CAAAGLDVAGWHDSPIDGGDGNREFFIHARRKA
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730486 [H]