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The map label for this gene is nhaR [H]

Identifier: 120612672

GI number: 120612672

Start: 4486099

End: 4486998

Strand: Direct

Name: nhaR [H]

Synonym: Aave_4035

Alternate gene names: 120612672

Gene position: 4486099-4486998 (Clockwise)

Preceding gene: 120612669

Following gene: 120612674

Centisome position: 83.81

GC content: 70.89

Gene sequence:

>900_bases
ATGCGCCTCGAGCAGCTCAACTTTCATCACCTCTTCTACTTCTGGCGGGTGGCCAAGCTGGGCCACCTGACGCGGGCGGC
CGAGGAGGTGCATGCCTCGCAGTCGGCGCTCTCCGCGCAGATCCGCCAGCTGGAGGAGCGGCTCGGCGAGCCGCTGTTCA
CGCGCGAAAACCGGCGGATGGTGCTGACCGAGGCAGGACAGGTGGTGCTGTCGTATGCCGAAGACATCTTCGGCCTGGGC
CAGGAGCTGCTGGGGCGGCTGCAGGGCCGCAGCCAGGGGATGACACGGCTGCGCGTGGGCGCGGTCGCCACCATGTCGCG
CAACTACCAGGAGAACCTGCTGCGCCCGCTGCTGGCCGACCCCGACGTGGTGCTGACCCTCGAATCGGGCCTGCTGGACG
ACCTGCTGCAGCGGCTGCTCGAGCACCAGCTGGACGTGGTGCTGGCCAACCAGAGCGTGCCCGCCGACCCGGGCCGGCCG
CTGCACTGCCGCTTCCTGGCCAGCCAGGCCATCTCCATCGTGGGCCCGGCCCACCGCTGGCCGGCCGGCGGCCTGCGCGT
GCCGCAGGACCTGCACGGCATGGACATCGCCCTGCCCGGCCCCCGCCATGCCGTGCGCGGGCCCTTCGATGCTCTGTGCG
CTTCGGCCGGCGTGGCACCGCGCCTGCGCGCCGAAGTGGACGACATGGCCCTGCTGCGCCTCATCGCCCGCGACAGCGGC
TGGCTGTCGCTGCTGTCCGAGGTGGTGGTGCAGGACGAGCTGAAAAGCGGGCTGCTGGTGATCGCGGGCCAGTCGAGCGA
ACTGACCGAGAGCTTCTACGCCATCACGGTGCCGCGGCGGCACCGGGTGGAGGCGCTGGAGAAGTTGCTGGGTGTGCAAG
CCGCCCAAGAAGCGGCGTAA

Upstream 100 bases:

>100_bases
GAGAAGAAAGTCGAGGTCTTGCATGGGTCGCCATGGTGGCGAGCCGCACATGTTCTGTAAAATTCATTAAAGGAAACAGA
TTGATCTTTTAAACAGAACA

Downstream 100 bases:

>100_bases
GCCCCCTCACTCCACCGTCACGCTCTTCGCCAGATTCCGCGGCTTGTCCACGTCCGTCCCGCGCGCGCACGCCGTGTGGT
ACGCCAGCAGCTGCAGCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MRLEQLNFHHLFYFWRVAKLGHLTRAAEEVHASQSALSAQIRQLEERLGEPLFTRENRRMVLTEAGQVVLSYAEDIFGLG
QELLGRLQGRSQGMTRLRVGAVATMSRNYQENLLRPLLADPDVVLTLESGLLDDLLQRLLEHQLDVVLANQSVPADPGRP
LHCRFLASQAISIVGPAHRWPAGGLRVPQDLHGMDIALPGPRHAVRGPFDALCASAGVAPRLRAEVDDMALLRLIARDSG
WLSLLSEVVVQDELKSGLLVIAGQSSELTESFYAITVPRRHRVEALEKLLGVQAAQEAA

Sequences:

>Translated_299_residues
MRLEQLNFHHLFYFWRVAKLGHLTRAAEEVHASQSALSAQIRQLEERLGEPLFTRENRRMVLTEAGQVVLSYAEDIFGLG
QELLGRLQGRSQGMTRLRVGAVATMSRNYQENLLRPLLADPDVVLTLESGLLDDLLQRLLEHQLDVVLANQSVPADPGRP
LHCRFLASQAISIVGPAHRWPAGGLRVPQDLHGMDIALPGPRHAVRGPFDALCASAGVAPRLRAEVDDMALLRLIARDSG
WLSLLSEVVVQDELKSGLLVIAGQSSELTESFYAITVPRRHRVEALEKLLGVQAAQEAA
>Mature_299_residues
MRLEQLNFHHLFYFWRVAKLGHLTRAAEEVHASQSALSAQIRQLEERLGEPLFTRENRRMVLTEAGQVVLSYAEDIFGLG
QELLGRLQGRSQGMTRLRVGAVATMSRNYQENLLRPLLADPDVVLTLESGLLDDLLQRLLEHQLDVVLANQSVPADPGRP
LHCRFLASQAISIVGPAHRWPAGGLRVPQDLHGMDIALPGPRHAVRGPFDALCASAGVAPRLRAEVDDMALLRLIARDSG
WLSLLSEVVVQDELKSGLLVIAGQSSELTESFYAITVPRRHRVEALEKLLGVQAAQEAA

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=295, Percent_Identity=24.0677966101695, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI157672245, Length=240, Percent_Identity=32.5, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788887, Length=150, Percent_Identity=34, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788297, Length=230, Percent_Identity=25.6521739130435, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=279, Percent_Identity=25.4480286738351, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=307, Percent_Identity=26.0586319218241, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790208, Length=148, Percent_Identity=29.0540540540541, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33009; Mature: 33009

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLEQLNFHHLFYFWRVAKLGHLTRAAEEVHASQSALSAQIRQLEERLGEPLFTRENRRM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEE
VLTEAGQVVLSYAEDIFGLGQELLGRLQGRSQGMTRLRVGAVATMSRNYQENLLRPLLAD
EEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCC
PDVVLTLESGLLDDLLQRLLEHQLDVVLANQSVPADPGRPLHCRFLASQAISIVGPAHRW
CCEEEEECHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEHHHHHHHHHHHCCCCCCC
PAGGLRVPQDLHGMDIALPGPRHAVRGPFDALCASAGVAPRLRAEVDDMALLRLIARDSG
CCCCCCCCCCCCCCEEECCCCCHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCH
WLSLLSEVVVQDELKSGLLVIAGQSSELTESFYAITVPRRHRVEALEKLLGVQAAQEAA
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLEQLNFHHLFYFWRVAKLGHLTRAAEEVHASQSALSAQIRQLEERLGEPLFTRENRRM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEE
VLTEAGQVVLSYAEDIFGLGQELLGRLQGRSQGMTRLRVGAVATMSRNYQENLLRPLLAD
EEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCC
PDVVLTLESGLLDDLLQRLLEHQLDVVLANQSVPADPGRPLHCRFLASQAISIVGPAHRW
CCEEEEECHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEHHHHHHHHHHHCCCCCCC
PAGGLRVPQDLHGMDIALPGPRHAVRGPFDALCASAGVAPRLRAEVDDMALLRLIARDSG
CCCCCCCCCCCCCCEEECCCCCHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCH
WLSLLSEVVVQDELKSGLLVIAGQSSELTESFYAITVPRRHRVEALEKLLGVQAAQEAA
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]