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The map label for this gene is nadA [H]

Identifier: 120612491

GI number: 120612491

Start: 4277444

End: 4278571

Strand: Reverse

Name: nadA [H]

Synonym: Aave_3850

Alternate gene names: 120612491

Gene position: 4278571-4277444 (Counterclockwise)

Preceding gene: 120612492

Following gene: 120612490

Centisome position: 79.93

GC content: 70.12

Gene sequence:

>1128_bases
ATGACCACCGATACTCTCGCCCTCAAGCCCGTGGAATACGAACAGCCCGCCAGCGAGGGCGGGGGGGCATGTTCCACCCG
CCACGCCTGGGCTCGCGTGCCCGCGGAGCCCCTGCCGGCCGAACGCGCCGCGCTCAAGGAGCGCATCCGCGCGCTGCTGC
GCGAGAAGAACGCGGTGATGGTGTCGCATTACTACGTGCATCCCGACCTGCAGGACCTGGCGGAGGAAACCGGCGGCATC
GTCAGCGATTCGCTGGAGATGGCTCGCTTCGGGCGCGACCACGCCGCGCAGACGCTGGTCGTCTCGGGGGTGCGCTTCAT
GGGCGAGACGGCGAAGATACTGTCGCCCGAGAAGACGGTGCTCATGCCCGACCTGGACGCCACCTGCTCGCTGGACCTGG
GGTGCCCCGTGGACGCATTCAGCGCCTTCTGCGACGCGCATCCGGACCGCACCGTGGTCGTCTATGCCAACACCAGCGCC
GCGGTGAAGGCGCGGGCGGACTGGCTGGTCACTTCCAGCTGCGCGCTGGAGATCGTGGGCGCGCTGCATGCCGCCGGCCA
CAAGATCCTGTGGGCGCCCGACCGGCACCTGGGGGCCTATATCCAGCGGGAGACCGGGGCGGACATGCTGTTCTGGAACG
GCGCGTGCATCGTGCACGACGAGTTCAAGGCGGCGGAGCTGGAGGCGCTCAAGCGGGAGCATCCGCAGGCCCGGGTGCTG
GTGCATCCGGAGAGCCCGGCCGAGGTGGTGGCCCTGGCGGATGCGGTGGGCTCCACGAGCGCGATCCTCAAGGCGGCGCG
CGAGATGGACGCGCGCGAGTTCATCGTGGCGACGGACAACGGGATGATGCACAAGCTGCGTGCGCTCAATCCGGACAAGG
TGTTCCACGAGGCGCCCACGGCCGGCAACAGCGCCACCTGCAAGAGCTGCGCGCACTGCCCCTGGATGGCCATGAACGGC
CTGGCCGACGTGGCTCGCGTGCTGGAGACCGGCGCAAATGCCGCCCATGTCGATCCTGCCCTGATTCCGCGTGCGCGCCA
GCCCATCGACCGCATGCTCGCGTTCACCGCGGCGCTCAAGGGGGGGCAGCCCGCGGGCGCCCTGGTGCCGCGCATCGGCG
CGGCATGA

Upstream 100 bases:

>100_bases
ACCCGCTGGCCGCCGCGCCGCCCCGCTCGCCGCCTGTTCGCCGCGCGTTTTCCGAAACCCCAACGAGGCCCCGCAGAACC
GGCCCGATAGCCACCCCGCC

Downstream 100 bases:

>100_bases
CCTCTTCGGCCCGCATCGATTTCTCCACGCCGCTGGACCCGGCGGCACCGCGGCTGCGCCTGGCCTTCGCGGAGCCGCGC
GAGGTGCTGGTGGCCCGCTC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTTDTLALKPVEYEQPASEGGGACSTRHAWARVPAEPLPAERAALKERIRALLREKNAVMVSHYYVHPDLQDLAEETGGI
VSDSLEMARFGRDHAAQTLVVSGVRFMGETAKILSPEKTVLMPDLDATCSLDLGCPVDAFSAFCDAHPDRTVVVYANTSA
AVKARADWLVTSSCALEIVGALHAAGHKILWAPDRHLGAYIQRETGADMLFWNGACIVHDEFKAAELEALKREHPQARVL
VHPESPAEVVALADAVGSTSAILKAAREMDAREFIVATDNGMMHKLRALNPDKVFHEAPTAGNSATCKSCAHCPWMAMNG
LADVARVLETGANAAHVDPALIPRARQPIDRMLAFTAALKGGQPAGALVPRIGAA

Sequences:

>Translated_375_residues
MTTDTLALKPVEYEQPASEGGGACSTRHAWARVPAEPLPAERAALKERIRALLREKNAVMVSHYYVHPDLQDLAEETGGI
VSDSLEMARFGRDHAAQTLVVSGVRFMGETAKILSPEKTVLMPDLDATCSLDLGCPVDAFSAFCDAHPDRTVVVYANTSA
AVKARADWLVTSSCALEIVGALHAAGHKILWAPDRHLGAYIQRETGADMLFWNGACIVHDEFKAAELEALKREHPQARVL
VHPESPAEVVALADAVGSTSAILKAAREMDAREFIVATDNGMMHKLRALNPDKVFHEAPTAGNSATCKSCAHCPWMAMNG
LADVARVLETGANAAHVDPALIPRARQPIDRMLAFTAALKGGQPAGALVPRIGAA
>Mature_374_residues
TTDTLALKPVEYEQPASEGGGACSTRHAWARVPAEPLPAERAALKERIRALLREKNAVMVSHYYVHPDLQDLAEETGGIV
SDSLEMARFGRDHAAQTLVVSGVRFMGETAKILSPEKTVLMPDLDATCSLDLGCPVDAFSAFCDAHPDRTVVVYANTSAA
VKARADWLVTSSCALEIVGALHAAGHKILWAPDRHLGAYIQRETGADMLFWNGACIVHDEFKAAELEALKREHPQARVLV
HPESPAEVVALADAVGSTSAILKAAREMDAREFIVATDNGMMHKLRALNPDKVFHEAPTAGNSATCKSCAHCPWMAMNGL
ADVARVLETGANAAHVDPALIPRARQPIDRMLAFTAALKGGQPAGALVPRIGAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=333, Percent_Identity=62.7627627627628, Blast_Score=432, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40098; Mature: 39967

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDTLALKPVEYEQPASEGGGACSTRHAWARVPAEPLPAERAALKERIRALLREKNAVM
CCCCCEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEE
VSHYYVHPDLQDLAEETGGIVSDSLEMARFGRDHAAQTLVVSGVRFMGETAKILSPEKTV
EEEEEECCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCEE
LMPDLDATCSLDLGCPVDAFSAFCDAHPDRTVVVYANTSAAVKARADWLVTSSCALEIVG
EECCCCCCEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHH
ALHAAGHKILWAPDRHLGAYIQRETGADMLFWNGACIVHDEFKAAELEALKREHPQARVL
HHHHCCCEEEECCCHHHHHHEECCCCCCEEEECCEEEEECCCCHHHHHHHHHCCCCEEEE
VHPESPAEVVALADAVGSTSAILKAAREMDAREFIVATDNGMMHKLRALNPDKVFHEAPT
ECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCHHHHHHCCCC
AGNSATCKSCAHCPWMAMNGLADVARVLETGANAAHVDPALIPRARQPIDRMLAFTAALK
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHC
GGQPAGALVPRIGAA
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTDTLALKPVEYEQPASEGGGACSTRHAWARVPAEPLPAERAALKERIRALLREKNAVM
CCCCEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEE
VSHYYVHPDLQDLAEETGGIVSDSLEMARFGRDHAAQTLVVSGVRFMGETAKILSPEKTV
EEEEEECCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCEE
LMPDLDATCSLDLGCPVDAFSAFCDAHPDRTVVVYANTSAAVKARADWLVTSSCALEIVG
EECCCCCCEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHH
ALHAAGHKILWAPDRHLGAYIQRETGADMLFWNGACIVHDEFKAAELEALKREHPQARVL
HHHHCCCEEEECCCHHHHHHEECCCCCCEEEECCEEEEECCCCHHHHHHHHHCCCCEEEE
VHPESPAEVVALADAVGSTSAILKAAREMDAREFIVATDNGMMHKLRALNPDKVFHEAPT
ECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCHHHHHHCCCC
AGNSATCKSCAHCPWMAMNGLADVARVLETGANAAHVDPALIPRARQPIDRMLAFTAALK
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHC
GGQPAGALVPRIGAA
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA