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The map label for this gene is pabB [H]

Identifier: 120612490

GI number: 120612490

Start: 4275648

End: 4277447

Strand: Reverse

Name: pabB [H]

Synonym: Aave_3849

Alternate gene names: 120612490

Gene position: 4277447-4275648 (Counterclockwise)

Preceding gene: 120612491

Following gene: 120612489

Centisome position: 79.91

GC content: 74.22

Gene sequence:

>1800_bases
ATGACCTCTTCGGCCCGCATCGATTTCTCCACGCCGCTGGACCCGGCGGCACCGCGGCTGCGCCTGGCCTTCGCGGAGCC
GCGCGAGGTGCTGGTGGCCCGCTCGCTGCAGGAGGTTCGCCCCGTGCTCGATGCGGTGGACGCCGCAGCGCGGCGGGGGG
CATGGTGCGTGGGCTACCTGCGCTACGAGGCGGCGGGGGCGTTCGATGCGGCGCTCGCGACGCACCCGGCCGACGGGCCG
CTGGCGTGGTTCGCGGTGTATGGCGCCCCCTTGCCGGCAGGCCATGCGGCGGGCTGCGACGGCCTGCCCGGGGCCGGCGG
TGCGTCCGCGTCGGTGGAGGGCTGGAGCGGGCTGGACCGCCAGGACTTCGACAGGGCCTTCGGGCGCATCCAGCAGGCCA
TCCGTGACGGCGAGCTGTACCAGGTCAATTTCACCGCGCCGCTCAGGGGCCGGTTCGAGGGCAGCCCGGCGGCGTTGTTC
GGGGCCCTGCAGCGCGCGCAGCCGGACGGGTATGCCGCGCACATCGACACCGGAGACGAACAGGTGCTGTCGGTGTCTCC
CGAACTGTTCTTCGACTGGCGTTCGGGGCCGGCGGGCGGGTCGATCCTGGCCCGCCCGATGAAGGGCACGGCACCGCGGG
GCGCCACGCCCGAGGCGGACGAGGCCCGGGCGGAGCATCTGCGCACGGCGCCCAAGGAACGGGCCGAGAACGTGATGATC
GTGGACCTGCTGCGCAACGACCTCTCGCGCATCGCCGAGCCCCACAGCGTGCGCGTGCCGGCGCTTTTCCGCACCCAGGC
GCTGCCCACCGTGTGGCAGATGACGTCGGACGTGACGGCCCGCACACGGCCGGGCACCGGCCTCGCGGATGTGTTCGCCG
CGCTGTTTCCCTGTGGATCGGTCACGGGGGCGCCCAAGGTGCAGGCGATGCGGGCCATCCGTGCGCTGGAGGCCGCGCCG
CGCGGGGTGTACTGCGGGGCGCTGGGGGTGGTGCGCCCCGACGGCTCGCCCGGAGAGGGCGGTATCGCGGCCACCTTCAA
CGTGCCGATCCGCACCGTGGTGTTGCGTGGCGGCGCGGCGGAATGCGGCATCGGCAGCGGCATCACCTCCGATGCGCGGG
CGGGCGCCGAATGGGACGAGTGGCGCCACAAGCGGGCCTTCGTGGAGCGGGCCAGCCAGCCTTTCGAGGTGCTGGAGACG
CTGGCGCTGCAGGAGGGAGGTTTCCGCCACCGGGAAGAGCACCTGGCGCGCATGGCTGCTTCCGCCGCGCATTTCGGTTT
TCCGTGGGATGCCGGCCGCGTGCATGCCTGTCTGGACGCCCTGGCGGCGGGGCATCCGCGGGGCCGGTGGCGCGCGCGGC
TGCTGCTGGATGCCGCCGGCCGGCCGCGCGCCGAAGCCTTCGCGTGCCCGGAGGTGGCGACGCCGGTGCGGCTGGCGCTG
GCGGACCGGCCTTTCGGCGCTGCGCACAGCGAGTTCGTGCGCCACAAGACCACGCGGCGTACGCACTATGCGGCCTTCGC
GCCCGCCGCGCCAGGGGTGTTCGATACGGTGCTCTGGAACGAGGCGGCGGAGATCACCGAGGGAACCTTCGGCAACATCG
CGGCGCTGCTGGACGGACGCTGGGTCACGCCGCCGCTGGCCTGCGGGTTGCTGCCCGGGGTGGGGCGGGCGGTCGCGCTG
CGCGAGGGGCGGCTCGTGGAGGCCGTGGTCCGGCTGGAGGACGTGCCCCGTGTGCGCGGATGGGCCTTCCTGAACAGCCT
GCGGGGCTGGCTGCCCGCGGAACTGGCCTCCGGGTCCTGA

Upstream 100 bases:

>100_bases
TTCCGCGTGCGCGCCAGCCCATCGACCGCATGCTCGCGTTCACCGCGGCGCTCAAGGGGGGGCAGCCCGCGGGCGCCCTG
GTGCCGCGCATCGGCGCGGC

Downstream 100 bases:

>100_bases
GCGCTCGCCCGGCACCCGGCTTCGGATCCGCGGCCGGCCGCTTCGCATCGCCGTGCATGGTTTCGCGCCGCGCCGCCGGC
ATGGCTGCCGCATCGATACC

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MTSSARIDFSTPLDPAAPRLRLAFAEPREVLVARSLQEVRPVLDAVDAAARRGAWCVGYLRYEAAGAFDAALATHPADGP
LAWFAVYGAPLPAGHAAGCDGLPGAGGASASVEGWSGLDRQDFDRAFGRIQQAIRDGELYQVNFTAPLRGRFEGSPAALF
GALQRAQPDGYAAHIDTGDEQVLSVSPELFFDWRSGPAGGSILARPMKGTAPRGATPEADEARAEHLRTAPKERAENVMI
VDLLRNDLSRIAEPHSVRVPALFRTQALPTVWQMTSDVTARTRPGTGLADVFAALFPCGSVTGAPKVQAMRAIRALEAAP
RGVYCGALGVVRPDGSPGEGGIAATFNVPIRTVVLRGGAAECGIGSGITSDARAGAEWDEWRHKRAFVERASQPFEVLET
LALQEGGFRHREEHLARMAASAAHFGFPWDAGRVHACLDALAAGHPRGRWRARLLLDAAGRPRAEAFACPEVATPVRLAL
ADRPFGAAHSEFVRHKTTRRTHYAAFAPAAPGVFDTVLWNEAAEITEGTFGNIAALLDGRWVTPPLACGLLPGVGRAVAL
REGRLVEAVVRLEDVPRVRGWAFLNSLRGWLPAELASGS

Sequences:

>Translated_599_residues
MTSSARIDFSTPLDPAAPRLRLAFAEPREVLVARSLQEVRPVLDAVDAAARRGAWCVGYLRYEAAGAFDAALATHPADGP
LAWFAVYGAPLPAGHAAGCDGLPGAGGASASVEGWSGLDRQDFDRAFGRIQQAIRDGELYQVNFTAPLRGRFEGSPAALF
GALQRAQPDGYAAHIDTGDEQVLSVSPELFFDWRSGPAGGSILARPMKGTAPRGATPEADEARAEHLRTAPKERAENVMI
VDLLRNDLSRIAEPHSVRVPALFRTQALPTVWQMTSDVTARTRPGTGLADVFAALFPCGSVTGAPKVQAMRAIRALEAAP
RGVYCGALGVVRPDGSPGEGGIAATFNVPIRTVVLRGGAAECGIGSGITSDARAGAEWDEWRHKRAFVERASQPFEVLET
LALQEGGFRHREEHLARMAASAAHFGFPWDAGRVHACLDALAAGHPRGRWRARLLLDAAGRPRAEAFACPEVATPVRLAL
ADRPFGAAHSEFVRHKTTRRTHYAAFAPAAPGVFDTVLWNEAAEITEGTFGNIAALLDGRWVTPPLACGLLPGVGRAVAL
REGRLVEAVVRLEDVPRVRGWAFLNSLRGWLPAELASGS
>Mature_598_residues
TSSARIDFSTPLDPAAPRLRLAFAEPREVLVARSLQEVRPVLDAVDAAARRGAWCVGYLRYEAAGAFDAALATHPADGPL
AWFAVYGAPLPAGHAAGCDGLPGAGGASASVEGWSGLDRQDFDRAFGRIQQAIRDGELYQVNFTAPLRGRFEGSPAALFG
ALQRAQPDGYAAHIDTGDEQVLSVSPELFFDWRSGPAGGSILARPMKGTAPRGATPEADEARAEHLRTAPKERAENVMIV
DLLRNDLSRIAEPHSVRVPALFRTQALPTVWQMTSDVTARTRPGTGLADVFAALFPCGSVTGAPKVQAMRAIRALEAAPR
GVYCGALGVVRPDGSPGEGGIAATFNVPIRTVVLRGGAAECGIGSGITSDARAGAEWDEWRHKRAFVERASQPFEVLETL
ALQEGGFRHREEHLARMAASAAHFGFPWDAGRVHACLDALAAGHPRGRWRARLLLDAAGRPRAEAFACPEVATPVRLALA
DRPFGAAHSEFVRHKTTRRTHYAAFAPAAPGVFDTVLWNEAAEITEGTFGNIAALLDGRWVTPPLACGLLPGVGRAVALR
EGRLVEAVVRLEDVPRVRGWAFLNSLRGWLPAELASGS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=265, Percent_Identity=34.7169811320755, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1787518, Length=282, Percent_Identity=31.2056737588652, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6320935, Length=266, Percent_Identity=34.2105263157895, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324361, Length=300, Percent_Identity=28.6666666666667, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 63777; Mature: 63646

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSARIDFSTPLDPAAPRLRLAFAEPREVLVARSLQEVRPVLDAVDAAARRGAWCVGYL
CCCCCEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
RYEAAGAFDAALATHPADGPLAWFAVYGAPLPAGHAAGCDGLPGAGGASASVEGWSGLDR
HHHHCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
QDFDRAFGRIQQAIRDGELYQVNFTAPLRGRFEGSPAALFGALQRAQPDGYAAHIDTGDE
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCC
QVLSVSPELFFDWRSGPAGGSILARPMKGTAPRGATPEADEARAEHLRTAPKERAENVMI
CEEEECCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCEEE
VDLLRNDLSRIAEPHSVRVPALFRTQALPTVWQMTSDVTARTRPGTGLADVFAALFPCGS
HHHHHHHHHHHCCCCCEECCHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCC
VTGAPKVQAMRAIRALEAAPRGVYCGALGVVRPDGSPGEGGIAATFNVPIRTVVLRGGAA
CCCCHHHHHHHHHHHHHHCCCCEEECEEEEECCCCCCCCCCEEEEECCCEEEEEEECCCC
ECGIGSGITSDARAGAEWDEWRHKRAFVERASQPFEVLETLALQEGGFRHREEHLARMAA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
SAAHFGFPWDAGRVHACLDALAAGHPRGRWRARLLLDAAGRPRAEAFACPEVATPVRLAL
HHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHCCCCCCCCCCEEEE
ADRPFGAAHSEFVRHKTTRRTHYAAFAPAAPGVFDTVLWNEAAEITEGTFGNIAALLDGR
CCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCC
WVTPPLACGLLPGVGRAVALREGRLVEAVVRLEDVPRVRGWAFLNSLRGWLPAELASGS
CCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
TSSARIDFSTPLDPAAPRLRLAFAEPREVLVARSLQEVRPVLDAVDAAARRGAWCVGYL
CCCCEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
RYEAAGAFDAALATHPADGPLAWFAVYGAPLPAGHAAGCDGLPGAGGASASVEGWSGLDR
HHHHCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
QDFDRAFGRIQQAIRDGELYQVNFTAPLRGRFEGSPAALFGALQRAQPDGYAAHIDTGDE
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCC
QVLSVSPELFFDWRSGPAGGSILARPMKGTAPRGATPEADEARAEHLRTAPKERAENVMI
CEEEECCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCEEE
VDLLRNDLSRIAEPHSVRVPALFRTQALPTVWQMTSDVTARTRPGTGLADVFAALFPCGS
HHHHHHHHHHHCCCCCEECCHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCC
VTGAPKVQAMRAIRALEAAPRGVYCGALGVVRPDGSPGEGGIAATFNVPIRTVVLRGGAA
CCCCHHHHHHHHHHHHHHCCCCEEECEEEEECCCCCCCCCCEEEEECCCEEEEEEECCCC
ECGIGSGITSDARAGAEWDEWRHKRAFVERASQPFEVLETLALQEGGFRHREEHLARMAA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
SAAHFGFPWDAGRVHACLDALAAGHPRGRWRARLLLDAAGRPRAEAFACPEVATPVRLAL
HHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHCCCCCCCCCCEEEE
ADRPFGAAHSEFVRHKTTRRTHYAAFAPAAPGVFDTVLWNEAAEITEGTFGNIAALLDGR
CCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCC
WVTPPLACGLLPGVGRAVALREGRLVEAVVRLEDVPRVRGWAFLNSLRGWLPAELASGS
CCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]