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The map label for this gene is 120612400

Identifier: 120612400

GI number: 120612400

Start: 4173891

End: 4174562

Strand: Reverse

Name: 120612400

Synonym: Aave_3757

Alternate gene names: NA

Gene position: 4174562-4173891 (Counterclockwise)

Preceding gene: 120612401

Following gene: 120612399

Centisome position: 77.99

GC content: 59.38

Gene sequence:

>672_bases
ATGACCGCCGTTTTCAAACCCAAGTACATCAGCTTCGACTGCTACGGAACCCTGACCAATTTCCAGATGGCTCCGAGCGC
TCGCCGCCTGTTCGCCGATCGCATCCGTCCCGAGCAGATGGACGGGTTCTGCAAGGATTTCGCCGCCTACCGGCTCGACG
AGGTATTGGGCGACTGGAAACCATACTACGACGTGGTTTTCAACGCGGTGATGCGGACCGCCAACAAATGGAAGGTCCCG
TTCCGTGAAGCCGACGTGGCGGAAATCTACGCGTCGGTGCCGACCTGGGGCCCCCATCCGGACGTCACCGCGGGCCTCGC
GAAAATCGCCGGAAAGATTCCGCTGGTGATTATCTCGAATGCCATGGACAACCAGCTGGTGCACAACGTCGAGAAACTCG
GCGTCCCGTTCCATCGCGTATATACCGCACAGCAAGCCAAGGCCTACAAACCCCGCCTGCGCGCTTTCGAATACATGATC
GACCAGCTCAACGCGAAGCCCGAGGATTTTCTCCACGTATCGTCGAGCATGCGTTACGACCATATGTCGGCCTCGGACAT
CGGAATCCGGGACAAGGCTTTCGTCAACCGCGGGCACGAACCTGGAGTCCCCGCTTACAACTACGCTGAAATCGCCGATA
TCGGCGGTCTGCCGGGCTTGGTCGGGCTCTGA

Upstream 100 bases:

>100_bases
GCCATGGCAGGGGGCAGCCACTGCCCGATCTGATCGATCGCCGCGCCGGCTACTGACCCTTTCCCTTCCGCGTTCCTGTC
ACTCCACCACAAAGGCTCCA

Downstream 100 bases:

>100_bases
CCCCGCGCGCCCCGGACCGGTCGCTGTCCGGGGCGCCTCAGCCATCCAGCGCCACCGGCGGGCAGGGCGAGGGCACGTCC
CGCGTGCTGTACATTGACCG

Product: haloacid dehalogenase

Products: (R)-2-hydroxyacid; halide

Alternate protein names: HAD Family Hydrolase; Hydrolase; Haloalkanoic Acid Dehalogenase; Dehalogenase; 2-Haloacid Dehalogenase; Haloacid Dehalogenase-Like Hydrolase; Haloacid Dehalogenase; Haloacid Dehalogenase I; 2-Haloalkanoic Acid Dehalogenase; Haloacid Dehydrogenase; 2-Haloacid Halidohydrolase Type II; Haloacid Dehalogenase Type II Truncated; 2-Haloacid Halidohydrolase IVa; 2-Haloacid Halidohydrolase IVA; Dehalogenase Protein; HAD Superfamily Haloalkanoic Acid Dehalogenase

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTAVFKPKYISFDCYGTLTNFQMAPSARRLFADRIRPEQMDGFCKDFAAYRLDEVLGDWKPYYDVVFNAVMRTANKWKVP
FREADVAEIYASVPTWGPHPDVTAGLAKIAGKIPLVIISNAMDNQLVHNVEKLGVPFHRVYTAQQAKAYKPRLRAFEYMI
DQLNAKPEDFLHVSSSMRYDHMSASDIGIRDKAFVNRGHEPGVPAYNYAEIADIGGLPGLVGL

Sequences:

>Translated_223_residues
MTAVFKPKYISFDCYGTLTNFQMAPSARRLFADRIRPEQMDGFCKDFAAYRLDEVLGDWKPYYDVVFNAVMRTANKWKVP
FREADVAEIYASVPTWGPHPDVTAGLAKIAGKIPLVIISNAMDNQLVHNVEKLGVPFHRVYTAQQAKAYKPRLRAFEYMI
DQLNAKPEDFLHVSSSMRYDHMSASDIGIRDKAFVNRGHEPGVPAYNYAEIADIGGLPGLVGL
>Mature_222_residues
TAVFKPKYISFDCYGTLTNFQMAPSARRLFADRIRPEQMDGFCKDFAAYRLDEVLGDWKPYYDVVFNAVMRTANKWKVPF
READVAEIYASVPTWGPHPDVTAGLAKIAGKIPLVIISNAMDNQLVHNVEKLGVPFHRVYTAQQAKAYKPRLRAFEYMID
QLNAKPEDFLHVSSSMRYDHMSASDIGIRDKAFVNRGHEPGVPAYNYAEIADIGGLPGLVGL

Specific function: Unknown

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.8.1.2

Molecular weight: Translated: 25126; Mature: 24995

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVFKPKYISFDCYGTLTNFQMAPSARRLFADRIRPEQMDGFCKDFAAYRLDEVLGDWK
CCCCCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
PYYDVVFNAVMRTANKWKVPFREADVAEIYASVPTWGPHPDVTAGLAKIAGKIPLVIISN
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECC
AMDNQLVHNVEKLGVPFHRVYTAQQAKAYKPRLRAFEYMIDQLNAKPEDFLHVSSSMRYD
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
HMSASDIGIRDKAFVNRGHEPGVPAYNYAEIADIGGLPGLVGL
CCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TAVFKPKYISFDCYGTLTNFQMAPSARRLFADRIRPEQMDGFCKDFAAYRLDEVLGDWK
CCCCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
PYYDVVFNAVMRTANKWKVPFREADVAEIYASVPTWGPHPDVTAGLAKIAGKIPLVIISN
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECC
AMDNQLVHNVEKLGVPFHRVYTAQQAKAYKPRLRAFEYMIDQLNAKPEDFLHVSSSMRYD
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
HMSASDIGIRDKAFVNRGHEPGVPAYNYAEIADIGGLPGLVGL
CCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-haloacid; H2O

Specific reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA