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The map label for this gene is yecS [H]

Identifier: 120612398

GI number: 120612398

Start: 4172188

End: 4172850

Strand: Reverse

Name: yecS [H]

Synonym: Aave_3755

Alternate gene names: 120612398

Gene position: 4172850-4172188 (Counterclockwise)

Preceding gene: 120612399

Following gene: 120612397

Centisome position: 77.96

GC content: 69.08

Gene sequence:

>663_bases
ATGGGCGAGGTTGCCAGGCTCCTGGCCGACCACGGGCCTGCCTTCGGGCAGGCCCTTTTGCTGACCTGGAAGCTCACCGC
GCTGTCGTTCGTGCCGGGCGTCCTGCTGGGCATGGCGGTGGCGATGCTGCGGCTCTTTCCGCTGCCGCCGCTGCGCTGGG
TGCTCACCCTCTACGTCGAGACCTTCCGCAACATCCCCAGCGTGGCGCTGCTGATCTTCATCGTGTTCGCGCTGCCCGAT
CTCGAGTTCGTGATCGACTACGAGCCCAGCGTGGTGCTGACCCTGGTGCTGGTCTGCTCCGCGTTCACGGCGGACTATGT
CCGCTCGGGCATCAACACCATCCCCGGCGGACAGATCGAGGCCGCGCTCAGCCTGGGGATGCGGCCCGCGCGCATCATCT
GGTCGGTGGTGCTGCCGCAGGCGCTGCGCTCGGTGGTGCAGCCGATGACGTCGCTGCTCATCGCGCTGATGCTGTCCACC
TCGCTCGCGTCGCAGGTGCCGTTCCCGGGCCGGGAGCTCACCACGCTCGTCTCCAAGATCGCCACCGACTCCGCCGCCGG
CATGGCCGCCTTCGCCATCGCGGCCGCGATGTACGTGGCCAGCGGCCTGTTGATCGCCTGGGCCGGCGCCGCCCTGGACA
GGAAGCTGCGGATCCTGCGATGA

Upstream 100 bases:

>100_bases
ATCGAAGCCGACGGCACCTGGGCCAAGCTGTGGACGATCGCCATCGGCCAGCGCACCGGCAGCACGGCCGTCCCCACGCC
GCCCGCGCTGCCCTGACCCG

Downstream 100 bases:

>100_bases
ACCGCTCCCTCGAAGACATCCTGTTCGGCGCGCCGAACCCCCGCGCCCGCACGCTCACCCGCGGGATGAGCGTGGTCGCG
GCGGGCGTGCTGCTCCTGCT

Product: polar amino acid ABC transporter inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MGEVARLLADHGPAFGQALLLTWKLTALSFVPGVLLGMAVAMLRLFPLPPLRWVLTLYVETFRNIPSVALLIFIVFALPD
LEFVIDYEPSVVLTLVLVCSAFTADYVRSGINTIPGGQIEAALSLGMRPARIIWSVVLPQALRSVVQPMTSLLIALMLST
SLASQVPFPGRELTTLVSKIATDSAAGMAAFAIAAAMYVASGLLIAWAGAALDRKLRILR

Sequences:

>Translated_220_residues
MGEVARLLADHGPAFGQALLLTWKLTALSFVPGVLLGMAVAMLRLFPLPPLRWVLTLYVETFRNIPSVALLIFIVFALPD
LEFVIDYEPSVVLTLVLVCSAFTADYVRSGINTIPGGQIEAALSLGMRPARIIWSVVLPQALRSVVQPMTSLLIALMLST
SLASQVPFPGRELTTLVSKIATDSAAGMAAFAIAAAMYVASGLLIAWAGAALDRKLRILR
>Mature_219_residues
GEVARLLADHGPAFGQALLLTWKLTALSFVPGVLLGMAVAMLRLFPLPPLRWVLTLYVETFRNIPSVALLIFIVFALPDL
EFVIDYEPSVVLTLVLVCSAFTADYVRSGINTIPGGQIEAALSLGMRPARIIWSVVLPQALRSVVQPMTSLLIALMLSTS
LASQVPFPGRELTTLVSKIATDSAAGMAAFAIAAAMYVASGLLIAWAGAALDRKLRILR

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=181, Percent_Identity=34.8066298342541, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786873, Length=158, Percent_Identity=32.2784810126582, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786874, Length=226, Percent_Identity=26.9911504424779, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI48994930, Length=131, Percent_Identity=28.2442748091603, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1787030, Length=199, Percent_Identity=27.6381909547739, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23561; Mature: 23429

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEVARLLADHGPAFGQALLLTWKLTALSFVPGVLLGMAVAMLRLFPLPPLRWVLTLYVE
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TFRNIPSVALLIFIVFALPDLEFVIDYEPSVVLTLVLVCSAFTADYVRSGINTIPGGQIE
HHHCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
AALSLGMRPARIIWSVVLPQALRSVVQPMTSLLIALMLSTSLASQVPFPGRELTTLVSKI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ATDSAAGMAAFAIAAAMYVASGLLIAWAGAALDRKLRILR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GEVARLLADHGPAFGQALLLTWKLTALSFVPGVLLGMAVAMLRLFPLPPLRWVLTLYVE
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TFRNIPSVALLIFIVFALPDLEFVIDYEPSVVLTLVLVCSAFTADYVRSGINTIPGGQIE
HHHCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
AALSLGMRPARIIWSVVLPQALRSVVQPMTSLLIALMLSTSLASQVPFPGRELTTLVSKI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ATDSAAGMAAFAIAAAMYVASGLLIAWAGAALDRKLRILR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]