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The map label for this gene is rsmB [H]

Identifier: 120612086

GI number: 120612086

Start: 3791646

End: 3792920

Strand: Reverse

Name: rsmB [H]

Synonym: Aave_3433

Alternate gene names: 120612086

Gene position: 3792920-3791646 (Counterclockwise)

Preceding gene: 120612090

Following gene: 120612085

Centisome position: 70.86

GC content: 70.75

Gene sequence:

>1275_bases
ATGCACCCGAAAGCCCTTCTGGATGCCTGCGCGGAACTCGTCAGGCTCACCCTCCAATTCGAACACCCCGCCGATGCCGT
CGTGTCCCGCTATTTCCGGGACCACCGCTCCCTCGGTCCGCGCGAACGCGCCACCCTCGCCGAAACCGCCTATACCGTGC
TGCGCAAGAAGCTGCTGTTCGAGCAACTGGCGCGCTCCGGCTCCGGGCCGCGCGAGCGGCGCCTCGCCATCCTGGGCTTC
CACGGCCCGCGCGACTTCCTCAAGAGTGCGCTCTCCGATGCCGAGAAGAGCTGGCTCGACCAGTGCGACGCCGTGCCGCC
GTCCGACCTGCTGGAGCCGCACCGCCACAACCTGCCCGACTGGCTCGTGCAGCCGCTCCGGCGCCAAGTGGGCGAGGGCT
TCTGGGCCCTGGCGGACAGCCTGGCCCAGCCGGCGCCGCTCGACCTGCGCGTCAACGACCTGAACGCCAGGCGCGCCGAC
GTGCAGAAGGAACTGGCCAAGGCCGGCATTCCCGCAGTGCCCACGCCGTACTCCCCCTGGGGCCTGCGCGTGGAAGGCAA
ACCGGCGCTCACCAAGGTCGATGCGTTCGCGCGCGGCGCCGTCGAGGTGCAGGACGAGGGCTCGCAACTCCTCGCCCTGC
TGCTGCAGCCCCGCCGCGGCGAAATGGTGGTGGACTTCTGCGCCGGCGCGGGCGGCAAGACGCTCGCCATCGGCGCGGCC
ATGCGCAGCACCGGGCGGCTCTACGCGTTCGACGTCTCCGCCCACCGGCTCGACGCGCTCAAGCCGCGGCTGGCCCGCAG
CGGCCTCTCCAACGTGCACCCCGCCGCGATCGCGCACGAGCGCGACGAGCGCATCAAGCGCCTGGCCGGCAAGATCGACC
GCGTGCTGGTGGATGCACCATGCTCCGGCCTGGGCACCCTGCGCCGCAACCCGGACCTGAAATGGCGGCAGTCCCCCCAG
GCCGTCCAGGAACTGGTGGCCAAGCAGACCGCCATCCTGCAGAGCGCCGCGCGCCTGCTCAAGCCGGGCGGACGCCTGGT
GTACGCCACCTGCAGCATCCTGCCCGAGGAAAACGAGGGTATCGCGGAAGCCTTCAGTGCGGCACATTCCGACTTCGTGG
CGGAAGACGTGGGCACGCTGCTGGAGCAGCTCAAGGTCGAGGGCGCGGCCGGACTGTGCAGCGGGGGCGCCAGCGGCACT
GGTTATCTGCGCCTGTGGCCCCATCTGCACCAGACCGATGGCTTCTTCGCCGCGGTATGGACCCGGAAAGGCTGA

Upstream 100 bases:

>100_bases
GTGCCTGGCGCGCCGGAAAAATGCATACTGTTTTCTTTTGCAGCGCATTGCATTCCATAACAGTGACGCGCCCGGCACGC
ATGGATGGGACAATCCTCCC

Downstream 100 bases:

>100_bases
TTTCCCCCGGCTGATCCGCCGATGAAACACCGCGCATCGCGCGGTCTTGTGCAACTTCCCGGCCGCATCGGCTTCTAAAA
TCACTGAAGTGCCCTTCATC

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MHPKALLDACAELVRLTLQFEHPADAVVSRYFRDHRSLGPRERATLAETAYTVLRKKLLFEQLARSGSGPRERRLAILGF
HGPRDFLKSALSDAEKSWLDQCDAVPPSDLLEPHRHNLPDWLVQPLRRQVGEGFWALADSLAQPAPLDLRVNDLNARRAD
VQKELAKAGIPAVPTPYSPWGLRVEGKPALTKVDAFARGAVEVQDEGSQLLALLLQPRRGEMVVDFCAGAGGKTLAIGAA
MRSTGRLYAFDVSAHRLDALKPRLARSGLSNVHPAAIAHERDERIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWRQSPQ
AVQELVAKQTAILQSAARLLKPGGRLVYATCSILPEENEGIAEAFSAAHSDFVAEDVGTLLEQLKVEGAAGLCSGGASGT
GYLRLWPHLHQTDGFFAAVWTRKG

Sequences:

>Translated_424_residues
MHPKALLDACAELVRLTLQFEHPADAVVSRYFRDHRSLGPRERATLAETAYTVLRKKLLFEQLARSGSGPRERRLAILGF
HGPRDFLKSALSDAEKSWLDQCDAVPPSDLLEPHRHNLPDWLVQPLRRQVGEGFWALADSLAQPAPLDLRVNDLNARRAD
VQKELAKAGIPAVPTPYSPWGLRVEGKPALTKVDAFARGAVEVQDEGSQLLALLLQPRRGEMVVDFCAGAGGKTLAIGAA
MRSTGRLYAFDVSAHRLDALKPRLARSGLSNVHPAAIAHERDERIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWRQSPQ
AVQELVAKQTAILQSAARLLKPGGRLVYATCSILPEENEGIAEAFSAAHSDFVAEDVGTLLEQLKVEGAAGLCSGGASGT
GYLRLWPHLHQTDGFFAAVWTRKG
>Mature_424_residues
MHPKALLDACAELVRLTLQFEHPADAVVSRYFRDHRSLGPRERATLAETAYTVLRKKLLFEQLARSGSGPRERRLAILGF
HGPRDFLKSALSDAEKSWLDQCDAVPPSDLLEPHRHNLPDWLVQPLRRQVGEGFWALADSLAQPAPLDLRVNDLNARRAD
VQKELAKAGIPAVPTPYSPWGLRVEGKPALTKVDAFARGAVEVQDEGSQLLALLLQPRRGEMVVDFCAGAGGKTLAIGAA
MRSTGRLYAFDVSAHRLDALKPRLARSGLSNVHPAAIAHERDERIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWRQSPQ
AVQELVAKQTAILQSAARLLKPGGRLVYATCSILPEENEGIAEAFSAAHSDFVAEDVGTLLEQLKVEGAAGLCSGGASGT
GYLRLWPHLHQTDGFFAAVWTRKG

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=293, Percent_Identity=30.3754266211604, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI76150623, Length=293, Percent_Identity=30.3754266211604, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI32698918, Length=167, Percent_Identity=31.7365269461078, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI23199998, Length=256, Percent_Identity=30.859375, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI270288818, Length=256, Percent_Identity=30.859375, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI8922322, Length=256, Percent_Identity=30.859375, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI270288816, Length=256, Percent_Identity=30.859375, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI39995082, Length=376, Percent_Identity=26.063829787234, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI301336155, Length=358, Percent_Identity=26.2569832402235, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI11545785, Length=224, Percent_Identity=26.7857142857143, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI2367212, Length=312, Percent_Identity=31.7307692307692, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081985, Length=316, Percent_Identity=30.0632911392405, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17536757, Length=295, Percent_Identity=30.5084745762712, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115534021, Length=225, Percent_Identity=30.2222222222222, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71998419, Length=225, Percent_Identity=30.2222222222222, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25143471, Length=252, Percent_Identity=30.952380952381, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=298, Percent_Identity=27.5167785234899, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6319447, Length=322, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI22024126, Length=286, Percent_Identity=30.4195804195804, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355201, Length=281, Percent_Identity=29.1814946619217, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24668781, Length=172, Percent_Identity=30.2325581395349, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356513, Length=169, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920494, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46247; Mature: 46247

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPKALLDACAELVRLTLQFEHPADAVVSRYFRDHRSLGPRERATLAETAYTVLRKKLLF
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EQLARSGSGPRERRLAILGFHGPRDFLKSALSDAEKSWLDQCDAVPPSDLLEPHRHNLPD
HHHHHCCCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHCCCHH
WLVQPLRRQVGEGFWALADSLAQPAPLDLRVNDLNARRADVQKELAKAGIPAVPTPYSPW
HHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GLRVEGKPALTKVDAFARGAVEVQDEGSQLLALLLQPRRGEMVVDFCAGAGGKTLAIGAA
CEEECCCCCHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHH
MRSTGRLYAFDVSAHRLDALKPRLARSGLSNVHPAAIAHERDERIKRLAGKIDRVLVDAP
HHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCC
CSGLGTLRRNPDLKWRQSPQAVQELVAKQTAILQSAARLLKPGGRLVYATCSILPEENEG
CCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
IAEAFSAAHSDFVAEDVGTLLEQLKVEGAAGLCSGGASGTGYLRLWPHLHQTDGFFAAVW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEE
TRKG
ECCC
>Mature Secondary Structure
MHPKALLDACAELVRLTLQFEHPADAVVSRYFRDHRSLGPRERATLAETAYTVLRKKLLF
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EQLARSGSGPRERRLAILGFHGPRDFLKSALSDAEKSWLDQCDAVPPSDLLEPHRHNLPD
HHHHHCCCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHCCCHH
WLVQPLRRQVGEGFWALADSLAQPAPLDLRVNDLNARRADVQKELAKAGIPAVPTPYSPW
HHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GLRVEGKPALTKVDAFARGAVEVQDEGSQLLALLLQPRRGEMVVDFCAGAGGKTLAIGAA
CEEECCCCCHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHH
MRSTGRLYAFDVSAHRLDALKPRLARSGLSNVHPAAIAHERDERIKRLAGKIDRVLVDAP
HHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCC
CSGLGTLRRNPDLKWRQSPQAVQELVAKQTAILQSAARLLKPGGRLVYATCSILPEENEG
CCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
IAEAFSAAHSDFVAEDVGTLLEQLKVEGAAGLCSGGASGTGYLRLWPHLHQTDGFFAAVW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEE
TRKG
ECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]