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The map label for this gene is exbB [H]

Identifier: 120611968

GI number: 120611968

Start: 3663846

End: 3664562

Strand: Direct

Name: exbB [H]

Synonym: Aave_3312

Alternate gene names: 120611968

Gene position: 3663846-3664562 (Clockwise)

Preceding gene: 120611967

Following gene: 120611969

Centisome position: 68.45

GC content: 65.69

Gene sequence:

>717_bases
ATGGAATCGCATTTCGGCATTGCCAACGTATGGATCCAGGGTGATTTCGTCACCCGGGCCGTCGCCGTGCTGCTGCTCGG
CATGTCGCTCGCCTCGTGGATCGTCATCCTCATCAAGGCGCTGGACATCATCAAGTTCAAGAAACATGCCCGCGGGGCGC
GCGACTTCTGGCACAGCGAAGACTTCGCCGCCGGCATGGAAAAGCTGGGCAACGATCCGTCGAATCCGTTCCGGCATCTC
GCGCTCGAAGGTCGCGAAGCCACCGCGCACCACCGCAACACCAAGGCGCACCTGCACGACAGCCTCGACGTGAGCGACTG
GATCACGCGCAGCCTGCGCAACTGCATCGACGAATTCACCGCCCGCCTGCAGTCGGGCCTGGCGGTCCTGGCTTCGGTCG
GATCCACCGCGCCGTTCATCGGCCTCTTCGGCACCGTCTGGGGCATCTACCACGCCCTCGTGGCGATCGGCGCATCCGGC
CAGTCCACCATCGACAAGGTGGCCGGCCCCATCGGCGAGGCGCTCATCATGACCGCGCTGGGCCTGGCGGTGGCCATCCC
CGCGGTGCTGGGCTACAACGCGCTGGTGCGGGGCAACAAGTCCATCCTGAACGGCCTCAACAGCTTCGCGCATGACCTGC
ACGCCTACTTCGTGACCGGCGCCCGCGTCAGCGCCCCTGCCGACCAGGGCAAGGTCCTGCCCATCAAGAAAGGCTGA

Upstream 100 bases:

>100_bases
GCAAGCGCAACGGCGTGCCGGAAGCCATGTGGAACCTCGTTCCGGTCAATTTCGTCCTCGATTAAACGTCTCGCAACCTT
TTTCAGCTTCAGGAGTTCTC

Downstream 100 bases:

>100_bases
CGCGCCATGGCATTCGGAACCCAGGACGACGCCGACGAGGTGATGAACGAGATCAACATGACGCCCCTGGTGGACGTCAT
GCTGGTGCTGCTCATCATCT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MESHFGIANVWIQGDFVTRAVAVLLLGMSLASWIVILIKALDIIKFKKHARGARDFWHSEDFAAGMEKLGNDPSNPFRHL
ALEGREATAHHRNTKAHLHDSLDVSDWITRSLRNCIDEFTARLQSGLAVLASVGSTAPFIGLFGTVWGIYHALVAIGASG
QSTIDKVAGPIGEALIMTALGLAVAIPAVLGYNALVRGNKSILNGLNSFAHDLHAYFVTGARVSAPADQGKVLPIKKG

Sequences:

>Translated_238_residues
MESHFGIANVWIQGDFVTRAVAVLLLGMSLASWIVILIKALDIIKFKKHARGARDFWHSEDFAAGMEKLGNDPSNPFRHL
ALEGREATAHHRNTKAHLHDSLDVSDWITRSLRNCIDEFTARLQSGLAVLASVGSTAPFIGLFGTVWGIYHALVAIGASG
QSTIDKVAGPIGEALIMTALGLAVAIPAVLGYNALVRGNKSILNGLNSFAHDLHAYFVTGARVSAPADQGKVLPIKKG
>Mature_238_residues
MESHFGIANVWIQGDFVTRAVAVLLLGMSLASWIVILIKALDIIKFKKHARGARDFWHSEDFAAGMEKLGNDPSNPFRHL
ALEGREATAHHRNTKAHLHDSLDVSDWITRSLRNCIDEFTARLQSGLAVLASVGSTAPFIGLFGTVWGIYHALVAIGASG
QSTIDKVAGPIGEALIMTALGLAVAIPAVLGYNALVRGNKSILNGLNSFAHDLHAYFVTGARVSAPADQGKVLPIKKG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=236, Percent_Identity=30.9322033898305, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789381, Length=201, Percent_Identity=25.8706467661692, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25482; Mature: 25482

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESHFGIANVWIQGDFVTRAVAVLLLGMSLASWIVILIKALDIIKFKKHARGARDFWHSE
CCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCH
DFAAGMEKLGNDPSNPFRHLALEGREATAHHRNTKAHLHDSLDVSDWITRSLRNCIDEFT
HHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
ARLQSGLAVLASVGSTAPFIGLFGTVWGIYHALVAIGASGQSTIDKVAGPIGEALIMTAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GLAVAIPAVLGYNALVRGNKSILNGLNSFAHDLHAYFVTGARVSAPADQGKVLPIKKG
HHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEECCCCC
>Mature Secondary Structure
MESHFGIANVWIQGDFVTRAVAVLLLGMSLASWIVILIKALDIIKFKKHARGARDFWHSE
CCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCH
DFAAGMEKLGNDPSNPFRHLALEGREATAHHRNTKAHLHDSLDVSDWITRSLRNCIDEFT
HHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
ARLQSGLAVLASVGSTAPFIGLFGTVWGIYHALVAIGASGQSTIDKVAGPIGEALIMTAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GLAVAIPAVLGYNALVRGNKSILNGLNSFAHDLHAYFVTGARVSAPADQGKVLPIKKG
HHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]