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The map label for this gene is sbcB [H]

Identifier: 120611894

GI number: 120611894

Start: 3567144

End: 3568580

Strand: Reverse

Name: sbcB [H]

Synonym: Aave_3236

Alternate gene names: 120611894

Gene position: 3568580-3567144 (Counterclockwise)

Preceding gene: 120611896

Following gene: 120611893

Centisome position: 66.67

GC content: 71.26

Gene sequence:

>1437_bases
ATGCACACGTTTTTCTGGCACGACTACGAGACCTTCGGCGCGGACCCGCGGCGCGACCGCCCGGCGCAGTTCGCGGGCAT
CCGCACGGATGCGGACCTGAACGAGATCGGCGAGCCGGTGATGATCTACTGCCGCCCGGCGCCGGATTACCTGCCCGATC
CGGAGTCGTGCCTTCTCACCGGCATCACGCCGCAGCTGTGCCTGGAGCGCGGCCTGCCGGAGCACGAATTCGCCGCGCGC
ATCGAGGCGGAACTGGCCCGGCCCGGCACGATCGGCGTGGGCTACAACACGATCCGCTTCGACGACGAGATCACGCGCTT
CATGTTCTGGCGCAACCTGATCGACCCCTATGCACGGGAATGGCAGAACGAATGCGGCCGCTGGGACCTGCTGGACGTGG
TGCGCCTGACCTACGCGCTGCGCCCCGACGGCATCGAATGGCCGCGCAAGGAGGACGGATCGCCCAGCCTGAAGCTCGAA
CACCTGTCGCGCGCCAACGGCCTGGTGCACGAGGCCGCGCACGATGCGCTGTCGGACGTGCGCGCCACGATCGCGCTGGC
GCGGCTGATCCGCGAGCGCCAGCCGCGGCTGTTCGAGTTCGCGCTCGGCCTGCGCCGCAAGGACCGCGTGGCCGCGGAAC
TGCGCCTGCCCGCCACGGCCGATACCGCGCGCCCCTTCCTGCACGTGTCGGGCATGTTCCCGGCGGACCGCGGCTGCCTG
GGCATCCTGTGGCCCCTGGCCAGCCACCCGACCAACCGCAACGAGCTCATCGCGTGGGACCTTGCGCACGACCCGTCCGA
ACTGGCCGGCCTGGACGCCGCGCGCATCCGCGAGCGCCTCTTCACGCGCACCGCCGACCTGCCCGAGGGCGTGGCGCGGC
TGCCGGTCAAGAGCGTGCACCTGAACAAGTCCCCCATGGTGGTGGGCAACGTCAACACCCTCACGCCCGCGATGGCGCAG
CGCTGGGGCATCGACGTGGAGCGCGCCGCCGCCCATGCGGAACTCGCGCGGGCGCTGCCCGACATGAGCGCGATCTGGGC
CGAGGTGTTCGCGCGGCCCAGGGAGGCACCGGCCGACGTGGACCAGGACCTGTACGGCGGCTTCGTCGGCAACGAGGACC
GGCGCCGCCTGCAGCGGCTGCGCACGCTGCCGCCGCAGGAGCTGGCGCTGGCCCGGCCGGGTTTCGACGACGAGCGCCTG
GAAGAGCTGGCCTGGCGCTTCCGCGCACGCAATTTTCCCGAAACGCTGGACGAGGCGGACCGCGAGCGCTGGGAGGCGCT
GCGCGTGGCGCGCCTCATGGAAGGCGAGGGCGGCGGCCTGACGTTCGACGCGCTCTTCGCGCGGCTGGACACGCTGGGCG
AAACCGCGGACGAGCGTGGCGAGGCGATCCTGGGGGCGCTGTACGAATATGCAGAAAGCATCGCTCCCGATTTCTGA

Upstream 100 bases:

>100_bases
CGTCGTGTTTCTTCGTTGCATGCCCCATTGTCCACGCGCCGCGGCGGTGCCGGCATACTTGCGGGCTGGAGTTTTACGCG
CCGCTGCGCTTCACCGATCC

Downstream 100 bases:

>100_bases
CGGGCCCGAAGGCGCAGGCCGGGGGGAGCCCGCGCCCCTGGCGGCATCTGCCGGCGGGGTGGACGCCCTGCTGGCCTGGG
CGCGTGCCTGCCCGCGGCTG

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MHTFFWHDYETFGADPRRDRPAQFAGIRTDADLNEIGEPVMIYCRPAPDYLPDPESCLLTGITPQLCLERGLPEHEFAAR
IEAELARPGTIGVGYNTIRFDDEITRFMFWRNLIDPYAREWQNECGRWDLLDVVRLTYALRPDGIEWPRKEDGSPSLKLE
HLSRANGLVHEAAHDALSDVRATIALARLIRERQPRLFEFALGLRRKDRVAAELRLPATADTARPFLHVSGMFPADRGCL
GILWPLASHPTNRNELIAWDLAHDPSELAGLDAARIRERLFTRTADLPEGVARLPVKSVHLNKSPMVVGNVNTLTPAMAQ
RWGIDVERAAAHAELARALPDMSAIWAEVFARPREAPADVDQDLYGGFVGNEDRRRLQRLRTLPPQELALARPGFDDERL
EELAWRFRARNFPETLDEADRERWEALRVARLMEGEGGGLTFDALFARLDTLGETADERGEAILGALYEYAESIAPDF

Sequences:

>Translated_478_residues
MHTFFWHDYETFGADPRRDRPAQFAGIRTDADLNEIGEPVMIYCRPAPDYLPDPESCLLTGITPQLCLERGLPEHEFAAR
IEAELARPGTIGVGYNTIRFDDEITRFMFWRNLIDPYAREWQNECGRWDLLDVVRLTYALRPDGIEWPRKEDGSPSLKLE
HLSRANGLVHEAAHDALSDVRATIALARLIRERQPRLFEFALGLRRKDRVAAELRLPATADTARPFLHVSGMFPADRGCL
GILWPLASHPTNRNELIAWDLAHDPSELAGLDAARIRERLFTRTADLPEGVARLPVKSVHLNKSPMVVGNVNTLTPAMAQ
RWGIDVERAAAHAELARALPDMSAIWAEVFARPREAPADVDQDLYGGFVGNEDRRRLQRLRTLPPQELALARPGFDDERL
EELAWRFRARNFPETLDEADRERWEALRVARLMEGEGGGLTFDALFARLDTLGETADERGEAILGALYEYAESIAPDF
>Mature_478_residues
MHTFFWHDYETFGADPRRDRPAQFAGIRTDADLNEIGEPVMIYCRPAPDYLPDPESCLLTGITPQLCLERGLPEHEFAAR
IEAELARPGTIGVGYNTIRFDDEITRFMFWRNLIDPYAREWQNECGRWDLLDVVRLTYALRPDGIEWPRKEDGSPSLKLE
HLSRANGLVHEAAHDALSDVRATIALARLIRERQPRLFEFALGLRRKDRVAAELRLPATADTARPFLHVSGMFPADRGCL
GILWPLASHPTNRNELIAWDLAHDPSELAGLDAARIRERLFTRTADLPEGVARLPVKSVHLNKSPMVVGNVNTLTPAMAQ
RWGIDVERAAAHAELARALPDMSAIWAEVFARPREAPADVDQDLYGGFVGNEDRRRLQRLRTLPPQELALARPGFDDERL
EELAWRFRARNFPETLDEADRERWEALRVARLMEGEGGGLTFDALFARLDTLGETADERGEAILGALYEYAESIAPDF

Specific function: Also functions as a DNA deoxyribophosphodiesterase that release deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=482, Percent_Identity=45.850622406639, Blast_Score=400, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54127; Mature: 54127

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTFFWHDYETFGADPRRDRPAQFAGIRTDADLNEIGEPVMIYCRPAPDYLPDPESCLLT
CCCEEECCHHHHCCCCCCCCCCHHCCCCCCCCHHHCCCCEEEEEECCCCCCCCCHHHEEE
GITPQLCLERGLPEHEFAARIEAELARPGTIGVGYNTIRFDDEITRFMFWRNLIDPYARE
CCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHH
WQNECGRWDLLDVVRLTYALRPDGIEWPRKEDGSPSLKLEHLSRANGLVHEAAHDALSDV
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
RATIALARLIRERQPRLFEFALGLRRKDRVAAELRLPATADTARPFLHVSGMFPADRGCL
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCCCC
GILWPLASHPTNRNELIAWDLAHDPSELAGLDAARIRERLFTRTADLPEGVARLPVKSVH
EEEHHHHCCCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCHHHEE
LNKSPMVVGNVNTLTPAMAQRWGIDVERAAAHAELARALPDMSAIWAEVFARPREAPADV
CCCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
DQDLYGGFVGNEDRRRLQRLRTLPPQELALARPGFDDERLEELAWRFRARNFPETLDEAD
CHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
RERWEALRVARLMEGEGGGLTFDALFARLDTLGETADERGEAILGALYEYAESIAPDF
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHTFFWHDYETFGADPRRDRPAQFAGIRTDADLNEIGEPVMIYCRPAPDYLPDPESCLLT
CCCEEECCHHHHCCCCCCCCCCHHCCCCCCCCHHHCCCCEEEEEECCCCCCCCCHHHEEE
GITPQLCLERGLPEHEFAARIEAELARPGTIGVGYNTIRFDDEITRFMFWRNLIDPYARE
CCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHH
WQNECGRWDLLDVVRLTYALRPDGIEWPRKEDGSPSLKLEHLSRANGLVHEAAHDALSDV
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
RATIALARLIRERQPRLFEFALGLRRKDRVAAELRLPATADTARPFLHVSGMFPADRGCL
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCCCC
GILWPLASHPTNRNELIAWDLAHDPSELAGLDAARIRERLFTRTADLPEGVARLPVKSVH
EEEHHHHCCCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCHHHEE
LNKSPMVVGNVNTLTPAMAQRWGIDVERAAAHAELARALPDMSAIWAEVFARPREAPADV
CCCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
DQDLYGGFVGNEDRRRLQRLRTLPPQELALARPGFDDERLEELAWRFRARNFPETLDEAD
CHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
RERWEALRVARLMEGEGGGLTFDALFARLDTLGETADERGEAILGALYEYAESIAPDF
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]