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The map label for this gene is yfcG [H]

Identifier: 120611873

GI number: 120611873

Start: 3546460

End: 3547245

Strand: Direct

Name: yfcG [H]

Synonym: Aave_3215

Alternate gene names: 120611873

Gene position: 3546460-3547245 (Clockwise)

Preceding gene: 120611872

Following gene: 120611874

Centisome position: 66.25

GC content: 69.47

Gene sequence:

>786_bases
GTGCGGGGCTTTCGCGCACGGCCCCTGCGGCGCGCGGGCAAGCCGGCTACAGTGGCCCGCTACCCGTTCCCTGGAGCCCA
CAGCATGATCGACCTGCACTACTGGACCACCCCCAACGGCCACAAGATCACCATGTTCCTGGAGGAGGCCGGCCTGCCCT
ACCGCGTGCTGCCCGTGAACATCGGCCGCGGCGAGCAGTTCCGGCCCGGGTTCCTGCGCATCGCGCCCAACAACCGCATC
CCGGCCCTCGTGGACCACGATCCGGCCGGCGGCGGCGAGCCGGTTTCCGTCTTCGAATCCGGCGCCATCCTGCTCTACCT
GGCCGACAAGACCGGCCGGTTCATTCCGCAGGACCTGCGCGGCCGCACCGAGGCGCTGCAGTGGCTGTTCTGGCAGATGG
GCGGCCTGGGCCCGATGGCAGGGCAGAACCACCATTTCACGCAGTACGCGCCGGAGCCGGTGCCCTACGCCATCGACCGC
TACGTGAAGGAGACCGCGCGGCTCTACGGCGTGCTCGACAAGCACCTTTCGGACGGCCGCGAATACATCGCCGGCAGCTA
TTCGATCGCCGACATGGCCTGCTACCCCTGGATCGTGCCGCACGAGAAGCAGCGCCAGGACCTGAAGGATTTCCCGCACC
TCGCGCGCTGGTTCGGGCGCATCGCCGAGCGCCCCGCCACCGTGCGGGCCTACGACGTCGCGAAGTCGGTCAACACCGCG
CCCACGGTGGACGAGGACGCCAGGAAGATCCTGTTCGGGCAGGACGCCGGCACGGTGCGACGCTGA

Upstream 100 bases:

>100_bases
CCGATCCGGGCGTTCGACCCTCCCGCCGCCTGCGAGCGGCCGGGCCAGGGCGCGCAGTCTCCGGCGGGCTCCGCCCTCCG
TTGAAAGGGCGGCCCGCGCA

Downstream 100 bases:

>100_bases
CCGTGCTGACCGTGCTGGCCGGCGCCCGGCGCACCCCGCGCGGCCGCCGTCGCGCAGGTGACGGCCGGCCGCGCCGCATC
CCGCCTAGAGTGCGCCGCAT

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MRGFRARPLRRAGKPATVARYPFPGAHSMIDLHYWTTPNGHKITMFLEEAGLPYRVLPVNIGRGEQFRPGFLRIAPNNRI
PALVDHDPAGGGEPVSVFESGAILLYLADKTGRFIPQDLRGRTEALQWLFWQMGGLGPMAGQNHHFTQYAPEPVPYAIDR
YVKETARLYGVLDKHLSDGREYIAGSYSIADMACYPWIVPHEKQRQDLKDFPHLARWFGRIAERPATVRAYDVAKSVNTA
PTVDEDARKILFGQDAGTVRR

Sequences:

>Translated_261_residues
MRGFRARPLRRAGKPATVARYPFPGAHSMIDLHYWTTPNGHKITMFLEEAGLPYRVLPVNIGRGEQFRPGFLRIAPNNRI
PALVDHDPAGGGEPVSVFESGAILLYLADKTGRFIPQDLRGRTEALQWLFWQMGGLGPMAGQNHHFTQYAPEPVPYAIDR
YVKETARLYGVLDKHLSDGREYIAGSYSIADMACYPWIVPHEKQRQDLKDFPHLARWFGRIAERPATVRAYDVAKSVNTA
PTVDEDARKILFGQDAGTVRR
>Mature_261_residues
MRGFRARPLRRAGKPATVARYPFPGAHSMIDLHYWTTPNGHKITMFLEEAGLPYRVLPVNIGRGEQFRPGFLRIAPNNRI
PALVDHDPAGGGEPVSVFESGAILLYLADKTGRFIPQDLRGRTEALQWLFWQMGGLGPMAGQNHHFTQYAPEPVPYAIDR
YVKETARLYGVLDKHLSDGREYIAGSYSIADMACYPWIVPHEKQRQDLKDFPHLARWFGRIAERPATVRAYDVAKSVNTA
PTVDEDARKILFGQDAGTVRR

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=202, Percent_Identity=60.3960396039604, Blast_Score=257, Evalue=5e-70,
Organism=Escherichia coli, GI87082195, Length=220, Percent_Identity=41.3636363636364, Blast_Score=166, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324100, Length=234, Percent_Identity=31.6239316239316, Blast_Score=119, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28571670, Length=175, Percent_Identity=26.8571428571429, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17864592, Length=194, Percent_Identity=27.8350515463918, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17864596, Length=186, Percent_Identity=28.494623655914, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17864598, Length=193, Percent_Identity=29.0155440414508, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17864594, Length=203, Percent_Identity=29.064039408867, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 29439; Mature: 29439

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGFRARPLRRAGKPATVARYPFPGAHSMIDLHYWTTPNGHKITMFLEEAGLPYRVLPVN
CCCCCCCHHHHCCCCCEEEECCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEEEE
IGRGEQFRPGFLRIAPNNRIPALVDHDPAGGGEPVSVFESGAILLYLADKTGRFIPQDLR
CCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHC
GRTEALQWLFWQMGGLGPMAGQNHHFTQYAPEPVPYAIDRYVKETARLYGVLDKHLSDGR
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
EYIAGSYSIADMACYPWIVPHEKQRQDLKDFPHLARWFGRIAERPATVRAYDVAKSVNTA
HHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCC
PTVDEDARKILFGQDAGTVRR
CCCCCHHHEEEECCCCCCCCC
>Mature Secondary Structure
MRGFRARPLRRAGKPATVARYPFPGAHSMIDLHYWTTPNGHKITMFLEEAGLPYRVLPVN
CCCCCCCHHHHCCCCCEEEECCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEEEE
IGRGEQFRPGFLRIAPNNRIPALVDHDPAGGGEPVSVFESGAILLYLADKTGRFIPQDLR
CCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHC
GRTEALQWLFWQMGGLGPMAGQNHHFTQYAPEPVPYAIDRYVKETARLYGVLDKHLSDGR
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
EYIAGSYSIADMACYPWIVPHEKQRQDLKDFPHLARWFGRIAERPATVRAYDVAKSVNTA
HHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCC
PTVDEDARKILFGQDAGTVRR
CCCCCHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]