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The map label for this gene is dmsA [H]

Identifier: 120611872

GI number: 120611872

Start: 3544092

End: 3546443

Strand: Direct

Name: dmsA [H]

Synonym: Aave_3214

Alternate gene names: 120611872

Gene position: 3544092-3546443 (Clockwise)

Preceding gene: 120611871

Following gene: 120611873

Centisome position: 66.21

GC content: 72.45

Gene sequence:

>2352_bases
ATGCGCACCGACACACCCCGCTTCCGACCGCACAGCTCCCACTGGGGCGTGTTCTCCGCCGCCTGGGACGGCCAGACCCT
CTCCGTCCAGCCGCACCCCGGCGACCCGGACCCCAACCCGCTGATCGACAACCTGCCGGCCGCGCTGCGGCACCCGGTGC
GCGTGGCCACGCCCATGGTGCGCCGCGGCTGGCTCGAACGCGGCCCCGGGCCCGATGCGATGCGCGGCAGGGACGACTAC
GTGCCGATGCCCTGGGACGAGGTGCTGGACCTGCTCGCCGCAGAGCTGCGGCGCGTGAAGGACCGGTACGGCGCCGGGGC
CGTGTTCGGCGGCTCCTACGGCTGGTCGAGCGCCGGGCGGTTCCACCATGCGCAGAGCCAGGTGCACCGCTTCCTCAACA
CCACGCTGGGCGGCTACGTGCGCTCGGTCAACAGCTACAGCGCGGGCGCCTCCGGGCCCATGCTGCCCCACGTGATCGGC
ACCATGGAAGAAGTGGCGCGCCGCAACGTGACCTGGGAACAGATCGTGGAGCACACCGACGTCGTGCTGGCCTTCGGCGG
CATGGCGCTCAAGAACTCGCGCGTGGCCTCGGGCGGCATCAGCCGGCACGTGGAACGCGATGCCATGCGCAGCGCCGCGG
CCCGGGGCTGCCGCTTTGTCTCCATCAGCCCGATCCGCAGCGACCTTCCGGACGAAGCCGCCTTCGAGTGGCTGGCCCCC
GTGCCGAACACCGACACCGCGATGATGCTCGGCCTGGTGCACCAGATCGTGAGCGACGGCGCGCACGACCGCAGCTTCCT
GGCCCGCTGCTGCGACGGCTGGGAAACCTTCGAGGATTACCTTCTGGGCCGCGGCGACGGCGTGGCCAAGAGCTGCGCAT
GGGCCGCCCCCATCTGCGGGCTGCCGGAGCGGCAACTGGTGGACCTGGCGCGCTCCCTCGTGGGCAAGCGCGTGCTGGTG
GTGGTGGTGGCGCATTCGCTGCAGCGTGCCGAGCATGGCGAGCAGCCCGTGTGGATGGGCGCCGTGCTGGCGGCGGCGCT
CGGCCAGCTGGGCCTGCCCGGCGGCGGCTACAACTATGCGCTCGGCACGCTGGCGCACTACGGCAAGCGCAACAACGCCG
TGCCCGCGGCCGCCTTGCCGCAGGGCACCAACGGCATCCAGGCATTCATTCCGGTGGCCCGCATCAGCGACATGCTGCTC
CACCCCGGCCAGCCCTTCGACTACAACGGGCAGCGCCACACCTACCCGCACATCCGCCTGGCCTACTGGGCGGGCGGCAA
CCCCTTCCACCACCACCAGGACCTCCACCGCCTGGCCGAGGCCTTCCGCCAGCTCGAGACCTTCGTCGTGCACGAGATCG
CCTGGACCGCCACCGCCCGCCATGCCGACATCGTGCTGCCCTGCACCATGACGCTGGAGCGCGAGGACATCGGCGCCACG
CCGACGGACCCGCTGGTGGTGGCCATGCACCGCGTGGCGGAACCGCACGGCCTGGCGCGCGACGACTACGACATCTTCTG
CGACCTGGCGCGCCGCCTCGGCGGGCTGGAGGCCTTCAGCGAGGGCCGCGACACCCGCCAGTGGCTGGCCCATCTGTACG
AACGCACCCGCGCCGGGCTGGAGGCCCTCGGGCACGAGGCCCCCGGCTTCGACGCGTTCTGGGAGCGCGGTGAACTCACC
CTCCCGCAGAAAGAGGACGACGGCGGCGTGCTGCGGGCCCTGCGCGAAGACCCCGTCGCCAATGCACTGAAAACGCCCAG
CGGCAAGGTGCAGATCAGTTCGCCCACCGTAGCGGCCTTCGGCTACGCGGACTGCCCCGGCCACCCCGCCTGGCTGCCGC
CCCGCTACAGCCCCACGGCGGAACACCCGCTGTGGCTCGTGGCCAACCAGCCGGCCTCCAGGCTGCACAGCCAGCTCGAC
TTCGGCGGCCACAGCCAGTCCACCAAGCGCCGCGGCCGGGAAGTCTGCACGCTGCATCCGGACGCGGCCCGTGCCCGGGG
CATCGCGGATGGCGACATCGTGAGGATCTTCAACGAAGTCGGCGCCTGCCTGGCCAGCGCCCGCCTCGACGCCGGCATGC
GCAGCGACGTGGTGCAACTGCCCACGGGCGCATGGTACGACCCGGTGCCGGACGCCGGTGGGCGCTCCCTGTGCGTGCAC
GGCAATCCGAACGTGCTGACGCGGGACATCGGGACCTCCTCGCTGGCGCAGGGCTGCGCGGGGCAGCTGAGCACCGTGCA
GGTGGAGCGCTACACCGGGGAGCTGCCGCCGATCCGGGCGTTCGACCCTCCCGCCGCCTGCGAGCGGCCGGGCCAGGGCG
CGCAGTCTCCGGCGGGCTCCGCCCTCCGTTGA

Upstream 100 bases:

>100_bases
CACCTGATGGGCAAGGCCTTCGGCGACTTCATCGTGCAGGACATCGCCAACTACCGGCGGGCCGTCGAGAAGGGCCACCT
CAAGGCCGAGTGAGAACACC

Downstream 100 bases:

>100_bases
AAGGGCGGCCCGCGCAGTGCGGGGCTTTCGCGCACGGCCCCTGCGGCGCGCGGGCAAGCCGGCTACAGTGGCCCGCTACC
CGTTCCCTGGAGCCCACAGC

Product: molybdopterin oxidoreductase

Products: Biotin [C]

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 783; Mature: 783

Protein sequence:

>783_residues
MRTDTPRFRPHSSHWGVFSAAWDGQTLSVQPHPGDPDPNPLIDNLPAALRHPVRVATPMVRRGWLERGPGPDAMRGRDDY
VPMPWDEVLDLLAAELRRVKDRYGAGAVFGGSYGWSSAGRFHHAQSQVHRFLNTTLGGYVRSVNSYSAGASGPMLPHVIG
TMEEVARRNVTWEQIVEHTDVVLAFGGMALKNSRVASGGISRHVERDAMRSAAARGCRFVSISPIRSDLPDEAAFEWLAP
VPNTDTAMMLGLVHQIVSDGAHDRSFLARCCDGWETFEDYLLGRGDGVAKSCAWAAPICGLPERQLVDLARSLVGKRVLV
VVVAHSLQRAEHGEQPVWMGAVLAAALGQLGLPGGGYNYALGTLAHYGKRNNAVPAAALPQGTNGIQAFIPVARISDMLL
HPGQPFDYNGQRHTYPHIRLAYWAGGNPFHHHQDLHRLAEAFRQLETFVVHEIAWTATARHADIVLPCTMTLEREDIGAT
PTDPLVVAMHRVAEPHGLARDDYDIFCDLARRLGGLEAFSEGRDTRQWLAHLYERTRAGLEALGHEAPGFDAFWERGELT
LPQKEDDGGVLRALREDPVANALKTPSGKVQISSPTVAAFGYADCPGHPAWLPPRYSPTAEHPLWLVANQPASRLHSQLD
FGGHSQSTKRRGREVCTLHPDAARARGIADGDIVRIFNEVGACLASARLDAGMRSDVVQLPTGAWYDPVPDAGGRSLCVH
GNPNVLTRDIGTSSLAQGCAGQLSTVQVERYTGELPPIRAFDPPAACERPGQGAQSPAGSALR

Sequences:

>Translated_783_residues
MRTDTPRFRPHSSHWGVFSAAWDGQTLSVQPHPGDPDPNPLIDNLPAALRHPVRVATPMVRRGWLERGPGPDAMRGRDDY
VPMPWDEVLDLLAAELRRVKDRYGAGAVFGGSYGWSSAGRFHHAQSQVHRFLNTTLGGYVRSVNSYSAGASGPMLPHVIG
TMEEVARRNVTWEQIVEHTDVVLAFGGMALKNSRVASGGISRHVERDAMRSAAARGCRFVSISPIRSDLPDEAAFEWLAP
VPNTDTAMMLGLVHQIVSDGAHDRSFLARCCDGWETFEDYLLGRGDGVAKSCAWAAPICGLPERQLVDLARSLVGKRVLV
VVVAHSLQRAEHGEQPVWMGAVLAAALGQLGLPGGGYNYALGTLAHYGKRNNAVPAAALPQGTNGIQAFIPVARISDMLL
HPGQPFDYNGQRHTYPHIRLAYWAGGNPFHHHQDLHRLAEAFRQLETFVVHEIAWTATARHADIVLPCTMTLEREDIGAT
PTDPLVVAMHRVAEPHGLARDDYDIFCDLARRLGGLEAFSEGRDTRQWLAHLYERTRAGLEALGHEAPGFDAFWERGELT
LPQKEDDGGVLRALREDPVANALKTPSGKVQISSPTVAAFGYADCPGHPAWLPPRYSPTAEHPLWLVANQPASRLHSQLD
FGGHSQSTKRRGREVCTLHPDAARARGIADGDIVRIFNEVGACLASARLDAGMRSDVVQLPTGAWYDPVPDAGGRSLCVH
GNPNVLTRDIGTSSLAQGCAGQLSTVQVERYTGELPPIRAFDPPAACERPGQGAQSPAGSALR
>Mature_783_residues
MRTDTPRFRPHSSHWGVFSAAWDGQTLSVQPHPGDPDPNPLIDNLPAALRHPVRVATPMVRRGWLERGPGPDAMRGRDDY
VPMPWDEVLDLLAAELRRVKDRYGAGAVFGGSYGWSSAGRFHHAQSQVHRFLNTTLGGYVRSVNSYSAGASGPMLPHVIG
TMEEVARRNVTWEQIVEHTDVVLAFGGMALKNSRVASGGISRHVERDAMRSAAARGCRFVSISPIRSDLPDEAAFEWLAP
VPNTDTAMMLGLVHQIVSDGAHDRSFLARCCDGWETFEDYLLGRGDGVAKSCAWAAPICGLPERQLVDLARSLVGKRVLV
VVVAHSLQRAEHGEQPVWMGAVLAAALGQLGLPGGGYNYALGTLAHYGKRNNAVPAAALPQGTNGIQAFIPVARISDMLL
HPGQPFDYNGQRHTYPHIRLAYWAGGNPFHHHQDLHRLAEAFRQLETFVVHEIAWTATARHADIVLPCTMTLEREDIGAT
PTDPLVVAMHRVAEPHGLARDDYDIFCDLARRLGGLEAFSEGRDTRQWLAHLYERTRAGLEALGHEAPGFDAFWERGELT
LPQKEDDGGVLRALREDPVANALKTPSGKVQISSPTVAAFGYADCPGHPAWLPPRYSPTAEHPLWLVANQPASRLHSQLD
FGGHSQSTKRRGREVCTLHPDAARARGIADGDIVRIFNEVGACLASARLDAGMRSDVVQLPTGAWYDPVPDAGGRSLCVH
GNPNVLTRDIGTSSLAQGCAGQLSTVQVERYTGELPPIRAFDPPAACERPGQGAQSPAGSALR

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=778, Percent_Identity=38.0462724935733, Blast_Score=516, Evalue=1e-147,
Organism=Escherichia coli, GI145693196, Length=776, Percent_Identity=37.3711340206186, Blast_Score=503, Evalue=1e-143,
Organism=Escherichia coli, GI1787231, Length=790, Percent_Identity=34.6835443037975, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI87081797, Length=742, Percent_Identity=27.6280323450135, Blast_Score=230, Evalue=3e-61,
Organism=Escherichia coli, GI1787870, Length=748, Percent_Identity=27.6737967914438, Blast_Score=223, Evalue=4e-59,
Organism=Escherichia coli, GI171474008, Length=743, Percent_Identity=26.2449528936743, Blast_Score=202, Evalue=8e-53,
Organism=Escherichia coli, GI3868721, Length=593, Percent_Identity=23.2715008431703, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 85045; Mature: 85045

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDTPRFRPHSSHWGVFSAAWDGQTLSVQPHPGDPDPNPLIDNLPAALRHPVRVATPMV
CCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCHHHCCCHHHHCCHHHHHHHH
RRGWLERGPGPDAMRGRDDYVPMPWDEVLDLLAAELRRVKDRYGAGAVFGGSYGWSSAGR
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCH
FHHAQSQVHRFLNTTLGGYVRSVNSYSAGASGPMLPHVIGTMEEVARRNVTWEQIVEHTD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
VVLAFGGMALKNSRVASGGISRHVERDAMRSAAARGCRFVSISPIRSDLPDEAAFEWLAP
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCHHHHHHHHCC
VPNTDTAMMLGLVHQIVSDGAHDRSFLARCCDGWETFEDYLLGRGDGVAKSCAWAAPICG
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCC
LPERQLVDLARSLVGKRVLVVVVAHSLQRAEHGEQPVWMGAVLAAALGQLGLPGGGYNYA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
LGTLAHYGKRNNAVPAAALPQGTNGIQAFIPVARISDMLLHPGQPFDYNGQRHTYPHIRL
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
AYWAGGNPFHHHQDLHRLAEAFRQLETFVVHEIAWTATARHADIVLPCTMTLEREDIGAT
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHHCCCC
PTDPLVVAMHRVAEPHGLARDDYDIFCDLARRLGGLEAFSEGRDTRQWLAHLYERTRAGL
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHH
EALGHEAPGFDAFWERGELTLPQKEDDGGVLRALREDPVANALKTPSGKVQISSPTVAAF
HHHCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCEEECCCCEEEE
GYADCPGHPAWLPPRYSPTAEHPLWLVANQPASRLHSQLDFGGHSQSTKRRGREVCTLHP
ECCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHCCCCEEEECC
DAARARGIADGDIVRIFNEVGACLASARLDAGMRSDVVQLPTGAWYDPVPDAGGRSLCVH
CHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCEEEEE
GNPNVLTRDIGTSSLAQGCAGQLSTVQVERYTGELPPIRAFDPPAACERPGQGAQSPAGS
CCCCEEEECCCHHHHHHHHCCCCCEEEEEHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
ALR
CCC
>Mature Secondary Structure
MRTDTPRFRPHSSHWGVFSAAWDGQTLSVQPHPGDPDPNPLIDNLPAALRHPVRVATPMV
CCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCHHHCCCHHHHCCHHHHHHHH
RRGWLERGPGPDAMRGRDDYVPMPWDEVLDLLAAELRRVKDRYGAGAVFGGSYGWSSAGR
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCH
FHHAQSQVHRFLNTTLGGYVRSVNSYSAGASGPMLPHVIGTMEEVARRNVTWEQIVEHTD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
VVLAFGGMALKNSRVASGGISRHVERDAMRSAAARGCRFVSISPIRSDLPDEAAFEWLAP
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCHHHHHHHHCC
VPNTDTAMMLGLVHQIVSDGAHDRSFLARCCDGWETFEDYLLGRGDGVAKSCAWAAPICG
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCC
LPERQLVDLARSLVGKRVLVVVVAHSLQRAEHGEQPVWMGAVLAAALGQLGLPGGGYNYA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
LGTLAHYGKRNNAVPAAALPQGTNGIQAFIPVARISDMLLHPGQPFDYNGQRHTYPHIRL
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
AYWAGGNPFHHHQDLHRLAEAFRQLETFVVHEIAWTATARHADIVLPCTMTLEREDIGAT
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHHCCCC
PTDPLVVAMHRVAEPHGLARDDYDIFCDLARRLGGLEAFSEGRDTRQWLAHLYERTRAGL
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHH
EALGHEAPGFDAFWERGELTLPQKEDDGGVLRALREDPVANALKTPSGKVQISSPTVAAF
HHHCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCEEECCCCEEEE
GYADCPGHPAWLPPRYSPTAEHPLWLVANQPASRLHSQLDFGGHSQSTKRRGREVCTLHP
ECCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHCCCCEEEECC
DAARARGIADGDIVRIFNEVGACLASARLDAGMRSDVVQLPTGAWYDPVPDAGGRSLCVH
CHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCEEEEE
GNPNVLTRDIGTSSLAQGCAGQLSTVQVERYTGELPPIRAFDPPAACERPGQGAQSPAGS
CCCCEEEECCCHHHHHHHHCCCCCEEEEEHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
ALR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]