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The map label for this gene is glmM

Identifier: 120611287

GI number: 120611287

Start: 2870006

End: 2871340

Strand: Direct

Name: glmM

Synonym: Aave_2619

Alternate gene names: 120611287

Gene position: 2870006-2871340 (Clockwise)

Preceding gene: 120611286

Following gene: 120611289

Centisome position: 53.62

GC content: 70.04

Gene sequence:

>1335_bases
ATGGCTCGCAAATATTTCGGTACGGACGGTATTCGTGGAACCGTGGGGCAGGCCCCCATCACGCCGGATTTCGTCCTGAG
GCTCGCGCATGCGGTGGGCCGGGTGCTGCGGCGCACGGAGGAGAGGCCGACGGTGCTGATCGGCAAGGACACGCGCATTT
CCGGCTACATGCTCGAGAGCGCGCTGGAGTCCGGCTTCAATTCGGCCGGCGTGGACGTGGTGCTGCTGGGGCCGCTGCCC
ACGCCGGGCGTCGCCTACCTCACGCGCGCGCAGCGCGCCAGCCTCGGCGTGGTGATCAGCGCCAGCCACAACGCCTACCC
CGACAACGGCATCAAGTTCTTCAGTGCGCAGGGCACCAAGCTGCCCGATGAATGGGAACTGGCGGTCGAGGCCGCCCTCG
ACGAGGCCCCGGCCTGGGCCGATTCGGCCTCCCTCGGCAAGGCCCGGCGCCTGGAGGATGCGGCCGGCCGCTACATCGAG
TTCTGCAAGAGCACTTTTTCCCAGGATCTCACCCTCAAGGGCACGAAGATCGTGGTGGATGCGGCGCACGGCGCGGCCTA
CCACATCGCGCCCAAGGTGTTCCACGAGCTGGGAGCCGAAGTGCTGGCCATCGGCTGCTCGCCCGACGGGCTCAACATCA
ACCACCAGGTGGGCGCCACCCATCCCGACGCGCTGGTGCGCGCGGTGCGCGCCAACCGTGCCGACTACGGTGTGGCGCTG
GACGGCGATGCGGACCGCCTGCAGATGGTGGATGCCGCCGGCCGGCTCTACAACGGCGACGAATTGCTCTACCTCCTGGC
GGCGGACCGCCTGTCGCGGGGGGAAAACGTCCCTGGCGTGGTGGGCACCCTGATGACCAACATGGCCGTGGAGCTCGCGC
TCAAGGCCGACGGCGTGGAGCTGGTCCGTGCCAAGGTGGGCGACCGCTATGTGCTGGAGGAACTGGCCCGCCGCCGCTGG
CTGCTGGGCGGCGAGAGCTCCGGCCACCTGCTGGCGCTGGACCGGCACACCACGGGCGACGGCCTGATCAGCGCGCTGCA
GGTGCTGCAGGCCTGCGTGCGCGGCGGCCGCAGCCTGGCGCGCACGCTGGAGCACGTGCGCCTTTTCCCGCAGGTGCTGG
TCAACGTCCGGCTGCTTCCCGGCCAGGACTGGAAGGCCAACACCGTGCTGCAGGACGCGCTGAAATCGGTGGAAGCCGAA
CTGGGCACGCAGGGGCGCGTGCTGGTGCGGGCCAGCGGGACCGAACCGCTGCTGCGCGTGATGGTGGAGACCTCGGATGC
GGACCGCGCCAGCCATTTCGCCCACCAGCTCGCCGACGCGGCCCGGGCGGGTTGA

Upstream 100 bases:

>100_bases
GCCGGCGCGGCCGCAGCCATAGCCGCCTTGGCGGCGCGCTCCCGCCGGAAAGCACGGGGCCAAGCCGGCAAAGCAAGAAG
AAACCAGCAGGAACATGACA

Downstream 100 bases:

>100_bases
AAAGGCCACCCGGCGCGGGAGCCGGCGGTCTGCCGCGCGGGGAAGCGGCTCAACCTTCGGGCCGTATCGTCCGCTGCTGC
AGCAGCGGCGTGATGGCCTG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MARKYFGTDGIRGTVGQAPITPDFVLRLAHAVGRVLRRTEERPTVLIGKDTRISGYMLESALESGFNSAGVDVVLLGPLP
TPGVAYLTRAQRASLGVVISASHNAYPDNGIKFFSAQGTKLPDEWELAVEAALDEAPAWADSASLGKARRLEDAAGRYIE
FCKSTFSQDLTLKGTKIVVDAAHGAAYHIAPKVFHELGAEVLAIGCSPDGLNINHQVGATHPDALVRAVRANRADYGVAL
DGDADRLQMVDAAGRLYNGDELLYLLAADRLSRGENVPGVVGTLMTNMAVELALKADGVELVRAKVGDRYVLEELARRRW
LLGGESSGHLLALDRHTTGDGLISALQVLQACVRGGRSLARTLEHVRLFPQVLVNVRLLPGQDWKANTVLQDALKSVEAE
LGTQGRVLVRASGTEPLLRVMVETSDADRASHFAHQLADAARAG

Sequences:

>Translated_444_residues
MARKYFGTDGIRGTVGQAPITPDFVLRLAHAVGRVLRRTEERPTVLIGKDTRISGYMLESALESGFNSAGVDVVLLGPLP
TPGVAYLTRAQRASLGVVISASHNAYPDNGIKFFSAQGTKLPDEWELAVEAALDEAPAWADSASLGKARRLEDAAGRYIE
FCKSTFSQDLTLKGTKIVVDAAHGAAYHIAPKVFHELGAEVLAIGCSPDGLNINHQVGATHPDALVRAVRANRADYGVAL
DGDADRLQMVDAAGRLYNGDELLYLLAADRLSRGENVPGVVGTLMTNMAVELALKADGVELVRAKVGDRYVLEELARRRW
LLGGESSGHLLALDRHTTGDGLISALQVLQACVRGGRSLARTLEHVRLFPQVLVNVRLLPGQDWKANTVLQDALKSVEAE
LGTQGRVLVRASGTEPLLRVMVETSDADRASHFAHQLADAARAG
>Mature_443_residues
ARKYFGTDGIRGTVGQAPITPDFVLRLAHAVGRVLRRTEERPTVLIGKDTRISGYMLESALESGFNSAGVDVVLLGPLPT
PGVAYLTRAQRASLGVVISASHNAYPDNGIKFFSAQGTKLPDEWELAVEAALDEAPAWADSASLGKARRLEDAAGRYIEF
CKSTFSQDLTLKGTKIVVDAAHGAAYHIAPKVFHELGAEVLAIGCSPDGLNINHQVGATHPDALVRAVRANRADYGVALD
GDADRLQMVDAAGRLYNGDELLYLLAADRLSRGENVPGVVGTLMTNMAVELALKADGVELVRAKVGDRYVLEELARRRWL
LGGESSGHLLALDRHTTGDGLISALQVLQACVRGGRSLARTLEHVRLFPQVLVNVRLLPGQDWKANTVLQDALKSVEAEL
GTQGRVLVRASGTEPLLRVMVETSDADRASHFAHQLADAARAG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=442, Percent_Identity=56.7873303167421, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1788361, Length=445, Percent_Identity=26.7415730337079, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_ACIAC (A1TQF3)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970965.1
- ProteinModelPortal:   A1TQF3
- SMR:   A1TQF3
- STRING:   A1TQF3
- GeneID:   4666593
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_2619
- NMPDR:   fig|397945.5.peg.2246
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   AHAVGRV
- PhylomeDB:   A1TQF3
- ProtClustDB:   PRK10887
- BioCyc:   AAVE397945:AAVE_2619-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47540; Mature: 47409

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKYFGTDGIRGTVGQAPITPDFVLRLAHAVGRVLRRTEERPTVLIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
ALESGFNSAGVDVVLLGPLPTPGVAYLTRAQRASLGVVISASHNAYPDNGIKFFSAQGTK
HHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEECCCCC
LPDEWELAVEAALDEAPAWADSASLGKARRLEDAAGRYIEFCKSTFSQDLTLKGTKIVVD
CCHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEE
AAHGAAYHIAPKVFHELGAEVLAIGCSPDGLNINHQVGATHPDALVRAVRANRADYGVAL
CCCCCEEEHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEE
DGDADRLQMVDAAGRLYNGDELLYLLAADRLSRGENVPGVVGTLMTNMAVELALKADGVE
CCCHHHHHHHHHHCCEECCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCHH
LVRAKVGDRYVLEELARRRWLLGGESSGHLLALDRHTTGDGLISALQVLQACVRGGRSLA
HHHHHHCCHHHHHHHHHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHH
RTLEHVRLFPQVLVNVRLLPGQDWKANTVLQDALKSVEAELGTQGRVLVRASGTEPLLRV
HHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHH
MVETSDADRASHFAHQLADAARAG
EEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARKYFGTDGIRGTVGQAPITPDFVLRLAHAVGRVLRRTEERPTVLIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
ALESGFNSAGVDVVLLGPLPTPGVAYLTRAQRASLGVVISASHNAYPDNGIKFFSAQGTK
HHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEECCCCC
LPDEWELAVEAALDEAPAWADSASLGKARRLEDAAGRYIEFCKSTFSQDLTLKGTKIVVD
CCHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEE
AAHGAAYHIAPKVFHELGAEVLAIGCSPDGLNINHQVGATHPDALVRAVRANRADYGVAL
CCCCCEEEHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEE
DGDADRLQMVDAAGRLYNGDELLYLLAADRLSRGENVPGVVGTLMTNMAVELALKADGVE
CCCHHHHHHHHHHCCEECCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCHH
LVRAKVGDRYVLEELARRRWLLGGESSGHLLALDRHTTGDGLISALQVLQACVRGGRSLA
HHHHHHCCHHHHHHHHHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHH
RTLEHVRLFPQVLVNVRLLPGQDWKANTVLQDALKSVEAELGTQGRVLVRASGTEPLLRV
HHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHH
MVETSDADRASHFAHQLADAARAG
EEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA