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The map label for this gene is sodB [H]

Identifier: 120611237

GI number: 120611237

Start: 2819361

End: 2819945

Strand: Direct

Name: sodB [H]

Synonym: Aave_2568

Alternate gene names: 120611237

Gene position: 2819361-2819945 (Clockwise)

Preceding gene: 120611236

Following gene: 120611240

Centisome position: 52.67

GC content: 61.54

Gene sequence:

>585_bases
ATGGAACATACCCTGCCACCGCTGCCTTACGCTATCGACGCCCTGGCTCCGCACTACAGCCAGGAAACCCTGGAGTACCA
CCATGGCAAGCACCACAATGCCTACGTGGTGAACCTCAACAACCTCCAGAAGGGCACCGAATTCGAGAACATGCCCCTCG
AGGAGATCATCAAGAAGTCCAGCGGCGGCATCTACAACAACGCCGCCCAGATCTGGAACCACACCTTCTTCTGGAACTGC
ATGGCTCCCAATGGCGGCGGCGAACCCTCGGGCGCGCTGGCCGACGCCATCAAGGCGAAGTGGGGCAGCTATGCCGCCTT
CAAGGAAGCCTTCGTGAAGAGCGCCGTGGGCAACTTCGGCTCCGGCTGGACCTGGCTGGTGAAGAAGGCGGACGGCAGCG
TGGACATCGTCAACACCGGTGCCGCCGGCACGCCCCTGACCACCGCCGACAAGGCGCTGCTGACCGTGGACGTCTGGGAG
CACGCCTACTACATCGACTACCGCAACCTGCGTCCCAAGTTCGTCGAAACCTTCCTCGACAAGCTGGTGAACTGGAAGTT
CGCGGAAAGCAATTTCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGAACGCGATTAACTTCCTACAATGCCGCCCTGTCGCGTCGCATGTCACACCGCGGCGTCGCACACGCAAGAATCACCA
ACCACCCACGAGGACCGCAC

Downstream 100 bases:

>100_bases
ATCCCACGCGCCTGAAACATGCCAGTCAGCCAGCCTGACTGGCATTTTTTTTCGCCGAAATTTACGAGCGCGGTCCTTGC
TGGGCGAGCCGCTGGCGTGT

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MEHTLPPLPYAIDALAPHYSQETLEYHHGKHHNAYVVNLNNLQKGTEFENMPLEEIIKKSSGGIYNNAAQIWNHTFFWNC
MAPNGGGEPSGALADAIKAKWGSYAAFKEAFVKSAVGNFGSGWTWLVKKADGSVDIVNTGAAGTPLTTADKALLTVDVWE
HAYYIDYRNLRPKFVETFLDKLVNWKFAESNFAA

Sequences:

>Translated_194_residues
MEHTLPPLPYAIDALAPHYSQETLEYHHGKHHNAYVVNLNNLQKGTEFENMPLEEIIKKSSGGIYNNAAQIWNHTFFWNC
MAPNGGGEPSGALADAIKAKWGSYAAFKEAFVKSAVGNFGSGWTWLVKKADGSVDIVNTGAAGTPLTTADKALLTVDVWE
HAYYIDYRNLRPKFVETFLDKLVNWKFAESNFAA
>Mature_194_residues
MEHTLPPLPYAIDALAPHYSQETLEYHHGKHHNAYVVNLNNLQKGTEFENMPLEEIIKKSSGGIYNNAAQIWNHTFFWNC
MAPNGGGEPSGALADAIKAKWGSYAAFKEAFVKSAVGNFGSGWTWLVKKADGSVDIVNTGAAGTPLTTADKALLTVDVWE
HAYYIDYRNLRPKFVETFLDKLVNWKFAESNFAA

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=205, Percent_Identity=39.5121951219512, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI67782305, Length=205, Percent_Identity=39.5121951219512, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI67782309, Length=196, Percent_Identity=33.1632653061224, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1787946, Length=194, Percent_Identity=65.4639175257732, Blast_Score=267, Evalue=4e-73,
Organism=Escherichia coli, GI1790342, Length=208, Percent_Identity=40.8653846153846, Blast_Score=146, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17506561, Length=202, Percent_Identity=39.1089108910891, Blast_Score=126, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17569479, Length=200, Percent_Identity=36.5, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6321796, Length=211, Percent_Identity=33.175355450237, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136812, Length=196, Percent_Identity=37.2448979591837, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 21553; Mature: 21553

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHTLPPLPYAIDALAPHYSQETLEYHHGKHHNAYVVNLNNLQKGTEFENMPLEEIIKKS
CCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHC
SGGIYNNAAQIWNHTFFWNCMAPNGGGEPSGALADAIKAKWGSYAAFKEAFVKSAVGNFG
CCCCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
SGWTWLVKKADGSVDIVNTGAAGTPLTTADKALLTVDVWEHAYYIDYRNLRPKFVETFLD
CCEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHH
KLVNWKFAESNFAA
HHHCCEECCCCCCC
>Mature Secondary Structure
MEHTLPPLPYAIDALAPHYSQETLEYHHGKHHNAYVVNLNNLQKGTEFENMPLEEIIKKS
CCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHC
SGGIYNNAAQIWNHTFFWNCMAPNGGGEPSGALADAIKAKWGSYAAFKEAFVKSAVGNFG
CCCCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
SGWTWLVKKADGSVDIVNTGAAGTPLTTADKALLTVDVWEHAYYIDYRNLRPKFVETFLD
CCEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHH
KLVNWKFAESNFAA
HHHCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8181762; 12910271 [H]