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The map label for this gene is xseA [H]

Identifier: 120611236

GI number: 120611236

Start: 2817920

End: 2819230

Strand: Direct

Name: xseA [H]

Synonym: Aave_2567

Alternate gene names: 120611236

Gene position: 2817920-2819230 (Clockwise)

Preceding gene: 120611228

Following gene: 120611237

Centisome position: 52.64

GC content: 72.92

Gene sequence:

>1311_bases
ATGTTTGAACGGCCGGACCCAGCAACGGCGCCGCGAATCTGGGACGTCGGGGCGCTGTGCCGCGCCGTTGCTGATGCGCT
GGAGGCGCGGTTCAATCCTGTGGCGGTGCGCGGGGAGATCACGGGCTTCTCGCGGGCTTCCAGCGGGCATTGCTACTTTT
CCATCAAGGACGGACAGGGACAGATCCGCTGCGCCATGTTCCGCCGCGCAGCCATGTTGCTCAACGGCACCCCGCGGGAC
GGGGAAATGGTCGAGCTGCGGGGACGGCTGGCGGTTTACGAAGCCCGGGGCGACCTGCAGCTCATCGTCGAGAGCCTGCA
GCGGGCAGGGCAGGGGGCGCTGTTCGAGCAATTCCTGCGGCTCAAGGCCCGGCTGGAATCGGAAGGCCTGTTCGACTCCG
CCCGCAAGCGCGGCCTGCCGGTCATGCCCCGCTCGATCGGGCTGGTCACCTCGCCGGGCGCCGCCGCGCTGCACGATGTG
GTGACCGCCCTGCGGCGGCGCGTTCCGCACCTGCCGGTGGTGCTGGCCCCGGCCCTGGTGCAGGGGGCGGCCGCGCCGGC
ATCGATCTGCACCGCCCTGCGCGCGCTCTACCGCATGGCCGAGCCGGGCGGCGGCGCAGGCCATCCGCCGGTGGAGGTGA
TCCTGCTGGTGCGCGGCGGCGGCTCCATCGAGGACCTGTGGGCCTTCAACGACGAGCAGGTCGCCCGCACGCTGGTGCAG
AGCCCCGTGCCGGTGGTGTCCGGGGTGGGCCATGAAACGGATTTCACCATCGCCGATTTCTGCGCCGACCTGCGGGCCCC
GACCCCCACGGCCGCGGCCGAACTGGTCGCGCAACCCCAGGCCACCTGGCTCGCAGGCATGGACGCGCTGGCCGGCCGCC
TGTCGGACAGCCTGCAGCGCCAGCTCGACGGGCGCCACCAGCGGCTGGACATGGCCGCCCAGCGGCTGGGGCGGCCGTCC
GGCCTGGTCACCCGGCAGGAACTGCGCCTCGCGCGCCTCGCGCAGCAGCTGCGCCACGGCGCGGCCTGGACGACCCAGCG
GTACGCCCAGCGGCAGGATGCCCTGGCAGACCGTTTGCCAAGGGCTGTGGCGCAGGGCGTGGCCCGGCAGGCGCAGCGGC
TGGACCATGCGGCATTGCGGCTGGAACTGCTCGACCCGCGCCTGGTGCTCCAGCGCGGCTATGCGCTGCTCACGGACAGC
GGGGGCCTGCCCGTGACCCGCACCGCCCAGGTACGCACCGGAGACGCCGTGCGCGCCGCCGTATCGGACGGCGAGATCGA
TCTGACGGTGTCTGCTCCGCGCCCGCTGTGA

Upstream 100 bases:

>100_bases
TTGCGCGCACATCCGGCCCACCTGTCCGCCACGCCGCAGGCTCCGCGCAGCTTGTGGACTATTGGGGCGGTGCCGCTCCC
CGCAAACCCTGGTGGCGCCG

Downstream 100 bases:

>100_bases
GCCCGGCATTCTGGGCCGTCGCCTACAACGCGGAACGCGATTAACTTCCTACAATGCCGCCCTGTCGCGTCGCATGTCAC
ACCGCGGCGTCGCACACGCA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MFERPDPATAPRIWDVGALCRAVADALEARFNPVAVRGEITGFSRASSGHCYFSIKDGQGQIRCAMFRRAAMLLNGTPRD
GEMVELRGRLAVYEARGDLQLIVESLQRAGQGALFEQFLRLKARLESEGLFDSARKRGLPVMPRSIGLVTSPGAAALHDV
VTALRRRVPHLPVVLAPALVQGAAAPASICTALRALYRMAEPGGGAGHPPVEVILLVRGGGSIEDLWAFNDEQVARTLVQ
SPVPVVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPQATWLAGMDALAGRLSDSLQRQLDGRHQRLDMAAQRLGRPS
GLVTRQELRLARLAQQLRHGAAWTTQRYAQRQDALADRLPRAVAQGVARQAQRLDHAALRLELLDPRLVLQRGYALLTDS
GGLPVTRTAQVRTGDAVRAAVSDGEIDLTVSAPRPL

Sequences:

>Translated_436_residues
MFERPDPATAPRIWDVGALCRAVADALEARFNPVAVRGEITGFSRASSGHCYFSIKDGQGQIRCAMFRRAAMLLNGTPRD
GEMVELRGRLAVYEARGDLQLIVESLQRAGQGALFEQFLRLKARLESEGLFDSARKRGLPVMPRSIGLVTSPGAAALHDV
VTALRRRVPHLPVVLAPALVQGAAAPASICTALRALYRMAEPGGGAGHPPVEVILLVRGGGSIEDLWAFNDEQVARTLVQ
SPVPVVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPQATWLAGMDALAGRLSDSLQRQLDGRHQRLDMAAQRLGRPS
GLVTRQELRLARLAQQLRHGAAWTTQRYAQRQDALADRLPRAVAQGVARQAQRLDHAALRLELLDPRLVLQRGYALLTDS
GGLPVTRTAQVRTGDAVRAAVSDGEIDLTVSAPRPL
>Mature_436_residues
MFERPDPATAPRIWDVGALCRAVADALEARFNPVAVRGEITGFSRASSGHCYFSIKDGQGQIRCAMFRRAAMLLNGTPRD
GEMVELRGRLAVYEARGDLQLIVESLQRAGQGALFEQFLRLKARLESEGLFDSARKRGLPVMPRSIGLVTSPGAAALHDV
VTALRRRVPHLPVVLAPALVQGAAAPASICTALRALYRMAEPGGGAGHPPVEVILLVRGGGSIEDLWAFNDEQVARTLVQ
SPVPVVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPQATWLAGMDALAGRLSDSLQRQLDGRHQRLDMAAQRLGRPS
GLVTRQELRLARLAQQLRHGAAWTTQRYAQRQDALADRLPRAVAQGVARQAQRLDHAALRLELLDPRLVLQRGYALLTDS
GGLPVTRTAQVRTGDAVRAAVSDGEIDLTVSAPRPL

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=455, Percent_Identity=36.9230769230769, Blast_Score=290, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 46959; Mature: 46959

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERPDPATAPRIWDVGALCRAVADALEARFNPVAVRGEITGFSRASSGHCYFSIKDGQG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCC
QIRCAMFRRAAMLLNGTPRDGEMVELRGRLAVYEARGDLQLIVESLQRAGQGALFEQFLR
CCHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHH
LKARLESEGLFDSARKRGLPVMPRSIGLVTSPGAAALHDVVTALRRRVPHLPVVLAPALV
HHHHHHHCCCHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
QGAAAPASICTALRALYRMAEPGGGAGHPPVEVILLVRGGGSIEDLWAFNDEQVARTLVQ
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHCCCHHHHHHHHHH
SPVPVVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPQATWLAGMDALAGRLSDSLQR
CCCCHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QLDGRHQRLDMAAQRLGRPSGLVTRQELRLARLAQQLRHGAAWTTQRYAQRQDALADRLP
HHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RAVAQGVARQAQRLDHAALRLELLDPRLVLQRGYALLTDSGGLPVTRTAQVRTGDAVRAA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCEEEEECCCCCCHHHEE
VSDGEIDLTVSAPRPL
ECCCCEEEEECCCCCC
>Mature Secondary Structure
MFERPDPATAPRIWDVGALCRAVADALEARFNPVAVRGEITGFSRASSGHCYFSIKDGQG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCC
QIRCAMFRRAAMLLNGTPRDGEMVELRGRLAVYEARGDLQLIVESLQRAGQGALFEQFLR
CCHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHH
LKARLESEGLFDSARKRGLPVMPRSIGLVTSPGAAALHDVVTALRRRVPHLPVVLAPALV
HHHHHHHCCCHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
QGAAAPASICTALRALYRMAEPGGGAGHPPVEVILLVRGGGSIEDLWAFNDEQVARTLVQ
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHCCCHHHHHHHHHH
SPVPVVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPQATWLAGMDALAGRLSDSLQR
CCCCHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QLDGRHQRLDMAAQRLGRPSGLVTRQELRLARLAQQLRHGAAWTTQRYAQRQDALADRLP
HHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RAVAQGVARQAQRLDHAALRLELLDPRLVLQRGYALLTDSGGLPVTRTAQVRTGDAVRAA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCEEEEECCCCCCHHHEE
VSDGEIDLTVSAPRPL
ECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA