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The map label for this gene is phbC [H]

Identifier: 120611148

GI number: 120611148

Start: 2707843

End: 2709555

Strand: Direct

Name: phbC [H]

Synonym: Aave_2477

Alternate gene names: 120611148

Gene position: 2707843-2709555 (Clockwise)

Preceding gene: 120611146

Following gene: 120611149

Centisome position: 50.59

GC content: 67.37

Gene sequence:

>1713_bases
ATGGATTTTGACGCAGGCTGGGCCGGCAGCGCCCGGCAGATCCAGCAGAAACTGAGCGAAAGCTGGATGCAGGCGCTGGA
GGCCTTCCGGCAGGCCGGTGGTTCCGCCGCCCCGGATGCCGGTGCCGCGCAGGCCCGTCCGGCCATCACCTTTTCTCCGG
ACAAGCTCGCCAGCCTGCAGCAGCAGTACGTGAAGGAGGCATCGGAGCTCTGGAGCCAGGCGCTCCAGCCGACCACCATG
AAGGACCGCCGGTTCAGCGCCCCCGCATGGGCCGAAAGCCCCATGGCGGCCTTCGCCGCCGCGTCCTACCTGCTCAATGC
CCGCACCCTGATGGGGCTGGCCGACGCGGTGGAGACCGACCCCAAGACGCGTGCGCGCATCCGCTTCGGCGTGGAGCAGT
GGATGGCTGCCATGGCGCCCAGCAATTTCCTCGTCTTCAACCCCGAGGCGCAGAAGAAGGCCATCGATTCCCAGGGCGAG
AGCCTGGCCAAGGGCATCGCCAACCTGCTGCACGACATGCGGCAGGGCCACGTGTCCATGACCGACGAAAGCGTCTTCGA
GGTGGGCCGCAACGTGGCCACCTCCGAGGGCGCCGTGGTGTACGAGAACGCGCTCTTACAGCTCATCGAGTACAAGCCGC
TCACGCCCAAGGTGCACCAGCGCCCGCTGCTGGTGGTGCCGCCCTGCATCAACAAGTTCTACATCCTCGACCTGCAGCCC
GAGAATTCGCTCATCCGGCATGCGGTGTCCGAAGGGCATCGCACTTTCGTGGTGAGCTGGCGCAACCCGGACCAGTCCCT
GGCGAACGCCACCTGGGACGACTACATCGAGGACGCGGTGCTCCGTGCCATCGACACCGTCCGCGAAATCTCTGGCAGCG
ACCAGATCAACGCGCTCGGCTTCTGCGTGGGCGGCACCATGCTGGCCACCGGCCTGGCCTTGTTGGCAGCCCGGGGCGAG
GAGCCCGTGGCCAGCGCCACCTTCCTCACCACGTTCATCGATTTCGCCGAAACCGGCATCCTCGATGTCTTCATCGACGA
GAGCTTCGTGCATTTCCGCGAACTGCAGATGGGGCAGGGCGGCCTGATGAAGGGGCAGGACCTCGCCTCCACGTTCAGCT
TCCTGCGGCCCAACGACCTCGTCTGGACTTACGTGGTGGGCAACTACCTGAAGGGCGAGACGCCGCCTCCCTTCGACCTG
CTCTACTGGAACAGCGATTCGACCAACCTGCCCGGGCCGTTCTACGCCTGGTACCTGCGCAACCTCTACCTCGAGAACAA
CCTCTGCAAGCCCGGCCGCCTGACCGTGTGCGGCGAGCCGATCGACCTGAACCTCGTGGACCTGCCCGCGTACATCTACG
GCTCGCGCGAGGACCACATCGTCCCGGTCGATGCCGCGTACGCGTCCACCCAGGTGCTGCCCGGCGACAAGCGCTTCGTG
ATGGGGGCCTCCGGCCACATCGCGGGCGTCATCAATCCCCCCGCCAAGAAGAAGCGCAGCCACTGGATCCGCGAGGACGG
CGTTCTGCCCGCCACGCTGCCCGAATGGCTGGACGGTGCGACGGAACTCCCCGGCAGCTGGTGGACCGACTGGGCCGCCT
GGCTGCGCGGCCATGCCGGCCCGCTCGTGGCCGCGCCCAAGCGCTACGGCAAGGGCGCGCGGTTCCAGGCCATCGAGCCG
GCACCGGGACGCTATGTGCGCGAGCGGGCCTGA

Upstream 100 bases:

>100_bases
CTTCCGGGCGTGGCGCTCGGCAACAATGCCAGGGCCGTGGTGCGATTTCCCCCGAGGCGCCGCCGCGATGGCATGATGGA
TGCTGCGAGGAGACACGTTC

Downstream 100 bases:

>100_bases
GGCGCCGCGCCACCCCTTTTCCCATCATTACCTTTGAGGATCGACATGGAAGACATCGTCATCGTTTCGGCCGTCCGCAC
GGCCGTGGGCAAGTTCGGCG

Product: poly(R)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MDFDAGWAGSARQIQQKLSESWMQALEAFRQAGGSAAPDAGAAQARPAITFSPDKLASLQQQYVKEASELWSQALQPTTM
KDRRFSAPAWAESPMAAFAAASYLLNARTLMGLADAVETDPKTRARIRFGVEQWMAAMAPSNFLVFNPEAQKKAIDSQGE
SLAKGIANLLHDMRQGHVSMTDESVFEVGRNVATSEGAVVYENALLQLIEYKPLTPKVHQRPLLVVPPCINKFYILDLQP
ENSLIRHAVSEGHRTFVVSWRNPDQSLANATWDDYIEDAVLRAIDTVREISGSDQINALGFCVGGTMLATGLALLAARGE
EPVASATFLTTFIDFAETGILDVFIDESFVHFRELQMGQGGLMKGQDLASTFSFLRPNDLVWTYVVGNYLKGETPPPFDL
LYWNSDSTNLPGPFYAWYLRNLYLENNLCKPGRLTVCGEPIDLNLVDLPAYIYGSREDHIVPVDAAYASTQVLPGDKRFV
MGASGHIAGVINPPAKKKRSHWIREDGVLPATLPEWLDGATELPGSWWTDWAAWLRGHAGPLVAAPKRYGKGARFQAIEP
APGRYVRERA

Sequences:

>Translated_570_residues
MDFDAGWAGSARQIQQKLSESWMQALEAFRQAGGSAAPDAGAAQARPAITFSPDKLASLQQQYVKEASELWSQALQPTTM
KDRRFSAPAWAESPMAAFAAASYLLNARTLMGLADAVETDPKTRARIRFGVEQWMAAMAPSNFLVFNPEAQKKAIDSQGE
SLAKGIANLLHDMRQGHVSMTDESVFEVGRNVATSEGAVVYENALLQLIEYKPLTPKVHQRPLLVVPPCINKFYILDLQP
ENSLIRHAVSEGHRTFVVSWRNPDQSLANATWDDYIEDAVLRAIDTVREISGSDQINALGFCVGGTMLATGLALLAARGE
EPVASATFLTTFIDFAETGILDVFIDESFVHFRELQMGQGGLMKGQDLASTFSFLRPNDLVWTYVVGNYLKGETPPPFDL
LYWNSDSTNLPGPFYAWYLRNLYLENNLCKPGRLTVCGEPIDLNLVDLPAYIYGSREDHIVPVDAAYASTQVLPGDKRFV
MGASGHIAGVINPPAKKKRSHWIREDGVLPATLPEWLDGATELPGSWWTDWAAWLRGHAGPLVAAPKRYGKGARFQAIEP
APGRYVRERA
>Mature_570_residues
MDFDAGWAGSARQIQQKLSESWMQALEAFRQAGGSAAPDAGAAQARPAITFSPDKLASLQQQYVKEASELWSQALQPTTM
KDRRFSAPAWAESPMAAFAAASYLLNARTLMGLADAVETDPKTRARIRFGVEQWMAAMAPSNFLVFNPEAQKKAIDSQGE
SLAKGIANLLHDMRQGHVSMTDESVFEVGRNVATSEGAVVYENALLQLIEYKPLTPKVHQRPLLVVPPCINKFYILDLQP
ENSLIRHAVSEGHRTFVVSWRNPDQSLANATWDDYIEDAVLRAIDTVREISGSDQINALGFCVGGTMLATGLALLAARGE
EPVASATFLTTFIDFAETGILDVFIDESFVHFRELQMGQGGLMKGQDLASTFSFLRPNDLVWTYVVGNYLKGETPPPFDL
LYWNSDSTNLPGPFYAWYLRNLYLENNLCKPGRLTVCGEPIDLNLVDLPAYIYGSREDHIVPVDAAYASTQVLPGDKRFV
MGASGHIAGVINPPAKKKRSHWIREDGVLPATLPEWLDGATELPGSWWTDWAAWLRGHAGPLVAAPKRYGKGARFQAIEP
APGRYVRERA

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 62791; Mature: 62791

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDAGWAGSARQIQQKLSESWMQALEAFRQAGGSAAPDAGAAQARPAITFSPDKLASLQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHHHHHH
QQYVKEASELWSQALQPTTMKDRRFSAPAWAESPMAAFAAASYLLNARTLMGLADAVETD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKTRARIRFGVEQWMAAMAPSNFLVFNPEAQKKAIDSQGESLAKGIANLLHDMRQGHVSM
CCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
TDESVFEVGRNVATSEGAVVYENALLQLIEYKPLTPKVHQRPLLVVPPCINKFYILDLQP
CHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCCCHHCCCEEEECCCCCCEEEEEECC
ENSLIRHAVSEGHRTFVVSWRNPDQSLANATWDDYIEDAVLRAIDTVREISGSDQINALG
CHHHHHHHHHCCCEEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
FCVGGTMLATGLALLAARGEEPVASATFLTTFIDFAETGILDVFIDESFVHFRELQMGQG
EHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCC
GLMKGQDLASTFSFLRPNDLVWTYVVGNYLKGETPPPFDLLYWNSDSTNLPGPFYAWYLR
CCCCCHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHH
NLYLENNLCKPGRLTVCGEPIDLNLVDLPAYIYGSREDHIVPVDAAYASTQVLPGDKRFV
HHHHCCCCCCCCCEEEECCCCCCEEEECCHHEECCCCCCEEEECCHHHCCEECCCCCEEE
MGASGHIAGVINPPAKKKRSHWIREDGVLPATLPEWLDGATELPGSWWTDWAAWLRGHAG
EECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCC
PLVAAPKRYGKGARFQAIEPAPGRYVRERA
CCEECCHHHCCCCCEEEECCCCCCHHHCCC
>Mature Secondary Structure
MDFDAGWAGSARQIQQKLSESWMQALEAFRQAGGSAAPDAGAAQARPAITFSPDKLASLQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHHHHHH
QQYVKEASELWSQALQPTTMKDRRFSAPAWAESPMAAFAAASYLLNARTLMGLADAVETD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKTRARIRFGVEQWMAAMAPSNFLVFNPEAQKKAIDSQGESLAKGIANLLHDMRQGHVSM
CCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
TDESVFEVGRNVATSEGAVVYENALLQLIEYKPLTPKVHQRPLLVVPPCINKFYILDLQP
CHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCCCHHCCCEEEECCCCCCEEEEEECC
ENSLIRHAVSEGHRTFVVSWRNPDQSLANATWDDYIEDAVLRAIDTVREISGSDQINALG
CHHHHHHHHHCCCEEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
FCVGGTMLATGLALLAARGEEPVASATFLTTFIDFAETGILDVFIDESFVHFRELQMGQG
EHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCC
GLMKGQDLASTFSFLRPNDLVWTYVVGNYLKGETPPPFDLLYWNSDSTNLPGPFYAWYLR
CCCCCHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHH
NLYLENNLCKPGRLTVCGEPIDLNLVDLPAYIYGSREDHIVPVDAAYASTQVLPGDKRFV
HHHHCCCCCCCCCEEEECCCCCCEEEECCHHEECCCCCCEEEECCHHHCCEECCCCCEEE
MGASGHIAGVINPPAKKKRSHWIREDGVLPATLPEWLDGATELPGSWWTDWAAWLRGHAG
EECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCC
PLVAAPKRYGKGARFQAIEPAPGRYVRERA
CCEECCHHHCCCCCEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670936; 1987116 [H]