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The map label for this gene is gsiC [H]

Identifier: 120610862

GI number: 120610862

Start: 2406872

End: 2407828

Strand: Direct

Name: gsiC [H]

Synonym: Aave_2188

Alternate gene names: 120610862

Gene position: 2406872-2407828 (Clockwise)

Preceding gene: 120610861

Following gene: 120610863

Centisome position: 44.96

GC content: 68.97

Gene sequence:

>957_bases
ATGAATCGTGTGATTCTCAAGCTCCTGGTGCAGCGCGTGCTGCTCGCGCTGCTGTCGCTGCTCGCGGTGTCTGCCGTGGT
GTTCGCCATCACGGCCGTGCTGCCCGGCGATGCGGCGCAGGAACAACTCGGACAGGACGCCACGCCCGAGGCGCTGGCCG
CGCTGCGGGCGCAGATGGGGCTGGATGTGCCCGCGCCCCTGCGCTACGCGCGCTGGCTGGGCGGAGCGGTCCGGGGTGAC
CTGGGCACTTCGGCGACCACGCAGATGCCGGTGCGCGAACTGATCGCGAGCCGGCTGCCCAATTCGCTGCTGCTCGCCGC
GGTGACGGCGCTTTTCTCGGTGCCCATCGCGCTGGCGCTCGGCATTGCCTGCGCGGTGTGGCGGGGCTCGTGGTTCGACC
GCGTGGTCTCCACCGGGGCGGTGGCGGTGGTTTCCGTGCCGGAATTCCTGGTGGCCACTCTCGCCGTGCTGGTGTTCGCC
GTGCAGTTGCGCTGGCTGCCCGCGCTGTCCTACGTGAACGACATCGAGTCCGTGGGCCAGATGCTGCGCGCCTTCGCCAT
GCCCGTGCTCAGCCTGTGCTGCGTGATCGTGGCGCAGATGATGCGCATGACCCGCGCGGCCGTCAGCGACCAGCTGCAGG
CACCCTACATCGAAATGGTCCGGCTCAAGGGCACCTCGCCCTTGCGCACCGTGATGGCGCATGCGCTGCCCAACGCCGTG
GGACCCATCGCCAACGCGGTCGCGCTGTCGCTGTCGTACCTGCTGGGGGGCGTGATCATCATCGAGACCATCTTCAACTA
CCCCGGCATCGCCAAGCTGATGGTGGACGGCGTGACCCAGCGGGACATGCCGCTGGTGCAGGCCTGCGCCATGATCTTCT
GCGCGGGCTACCTGATCCTCGTCACGCTGGCGGACCTGTGCGGCATCGTCGCCAATCCGCGCCTGCGTCACCGCTGA

Upstream 100 bases:

>100_bases
TGGCCCGCTCCGCGGCCGTCGGACGGGTGGCGCCGCGCCGGTTGCACGGGCTGCGGGTGGCGCGCAATGCGATGGAAAAC
GGATACGGATCGGACCCTTC

Downstream 100 bases:

>100_bases
CATTCCGCATTCCGACCAAGGAGCTCCCCCCGATGGACACCGTATCTCCTTCGCCCGGCGCGCCTGCGGCGCCCGCGGCC
CGGCACGGGCGCCTGCCCCG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNRVILKLLVQRVLLALLSLLAVSAVVFAITAVLPGDAAQEQLGQDATPEALAALRAQMGLDVPAPLRYARWLGGAVRGD
LGTSATTQMPVRELIASRLPNSLLLAAVTALFSVPIALALGIACAVWRGSWFDRVVSTGAVAVVSVPEFLVATLAVLVFA
VQLRWLPALSYVNDIESVGQMLRAFAMPVLSLCCVIVAQMMRMTRAAVSDQLQAPYIEMVRLKGTSPLRTVMAHALPNAV
GPIANAVALSLSYLLGGVIIIETIFNYPGIAKLMVDGVTQRDMPLVQACAMIFCAGYLILVTLADLCGIVANPRLRHR

Sequences:

>Translated_318_residues
MNRVILKLLVQRVLLALLSLLAVSAVVFAITAVLPGDAAQEQLGQDATPEALAALRAQMGLDVPAPLRYARWLGGAVRGD
LGTSATTQMPVRELIASRLPNSLLLAAVTALFSVPIALALGIACAVWRGSWFDRVVSTGAVAVVSVPEFLVATLAVLVFA
VQLRWLPALSYVNDIESVGQMLRAFAMPVLSLCCVIVAQMMRMTRAAVSDQLQAPYIEMVRLKGTSPLRTVMAHALPNAV
GPIANAVALSLSYLLGGVIIIETIFNYPGIAKLMVDGVTQRDMPLVQACAMIFCAGYLILVTLADLCGIVANPRLRHR
>Mature_318_residues
MNRVILKLLVQRVLLALLSLLAVSAVVFAITAVLPGDAAQEQLGQDATPEALAALRAQMGLDVPAPLRYARWLGGAVRGD
LGTSATTQMPVRELIASRLPNSLLLAAVTALFSVPIALALGIACAVWRGSWFDRVVSTGAVAVVSVPEFLVATLAVLVFA
VQLRWLPALSYVNDIESVGQMLRAFAMPVLSLCCVIVAQMMRMTRAAVSDQLQAPYIEMVRLKGTSPLRTVMAHALPNAV
GPIANAVALSLSYLLGGVIIIETIFNYPGIAKLMVDGVTQRDMPLVQACAMIFCAGYLILVTLADLCGIVANPRLRHR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=314, Percent_Identity=34.0764331210191, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1789965, Length=342, Percent_Identity=28.3625730994152, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1789888, Length=317, Percent_Identity=30.9148264984227, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787761, Length=307, Percent_Identity=30.2931596091205, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=27.7070063694268, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788504, Length=322, Percent_Identity=26.0869565217391, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787550, Length=274, Percent_Identity=23.7226277372263, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33836; Mature: 33836

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA