Click here to switch to the map view.

The map label for this gene is prpC [H]

Identifier: 120610156

GI number: 120610156

Start: 1623842

End: 1624591

Strand: Direct

Name: prpC [H]

Synonym: Aave_1469

Alternate gene names: 120610156

Gene position: 1623842-1624591 (Clockwise)

Preceding gene: 120610155

Following gene: 120610157

Centisome position: 30.34

GC content: 69.47

Gene sequence:

>750_bases
GTGATGGCGGCTTCGCTGTCGGAAAAGGGCGGCCGGGAGGTGAACGAGGATTTCCTGGGCATGGTGGACATGGGCCACCG
CGGCCTGTGCTGCGTGCTGGCCGACGGCGCGGGCGGGCACGGGCACGGCGGGCTGGCGGCCCGGATCACCGTGAACGCGG
TGCTCGAGGGCTTCGGTCACAACCCGCTGTTCGCGCCCGCGGGCCTGGCCTCGCTCATTTCGCTGGCCGAGCATGCGGTG
GCCGGCGCGCAGCCGCTTTCGATTTCGCGCAAGCACATGAGCGCCACCGTGGTGCTGCTGTGCATCGATCGCAAGACCGG
GCGCGCGCTCTGGGCGCATTGGGGGGATTCGAGGCTGTACTGGTTCAGGGACCAGAAGGTGCTTCAGATCACGGAGGATC
ACAGCGTCGTGCAGCAGCTGTTGCATGCGGGCGTGTATCGCAACCAGGATCCGCGGCGGCTGCCGAACCGCAGCGTGCTG
GCGGGTGCCATCGGCGCGGAATCGCAGATCCCGCCCACGGTGCTCCCGCGGCCCATCGAGCTGGCGGCCGGCGATGCGTT
CCTGCTCTGTTCGGACGGGCTCTGGGAGGGGCTGGACGAAGAGCAGATGGAGAGCGCCCTGCGTCACAGCCAGTCCCCGC
AGGAGTGGCTGGAGCAGATGGAGGCGGCCGTGCGGGCCCAGGCCAAGTCCTACCAGGACAACTTCAGCGCCCTCGCGGTC
TGGGTCGCGGACAGCGAGGATGGCGCCTGA

Upstream 100 bases:

>100_bases
TCTCCGGCCAGGCCTTCCTGGAGGCCTATGAAAACGCCGAGGCGGCGGCGAAGGCCAGGACGTGATCTTCCATATCGCAG
GCGAGGAGTTCCGGTTCCGG

Downstream 100 bases:

>100_bases
CAGGGCGGATGTGGCGTTTTCACCGGAACCTAAGGAGTCGGATATGCATCGGGAAGCGATGGCACGGAAGGGATTCATCA
GGGCGGGGCTCGCGGCCGCG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MMAASLSEKGGREVNEDFLGMVDMGHRGLCCVLADGAGGHGHGGLAARITVNAVLEGFGHNPLFAPAGLASLISLAEHAV
AGAQPLSISRKHMSATVVLLCIDRKTGRALWAHWGDSRLYWFRDQKVLQITEDHSVVQQLLHAGVYRNQDPRRLPNRSVL
AGAIGAESQIPPTVLPRPIELAAGDAFLLCSDGLWEGLDEEQMESALRHSQSPQEWLEQMEAAVRAQAKSYQDNFSALAV
WVADSEDGA

Sequences:

>Translated_249_residues
MMAASLSEKGGREVNEDFLGMVDMGHRGLCCVLADGAGGHGHGGLAARITVNAVLEGFGHNPLFAPAGLASLISLAEHAV
AGAQPLSISRKHMSATVVLLCIDRKTGRALWAHWGDSRLYWFRDQKVLQITEDHSVVQQLLHAGVYRNQDPRRLPNRSVL
AGAIGAESQIPPTVLPRPIELAAGDAFLLCSDGLWEGLDEEQMESALRHSQSPQEWLEQMEAAVRAQAKSYQDNFSALAV
WVADSEDGA
>Mature_249_residues
MMAASLSEKGGREVNEDFLGMVDMGHRGLCCVLADGAGGHGHGGLAARITVNAVLEGFGHNPLFAPAGLASLISLAEHAV
AGAQPLSISRKHMSATVVLLCIDRKTGRALWAHWGDSRLYWFRDQKVLQITEDHSVVQQLLHAGVYRNQDPRRLPNRSVL
AGAIGAESQIPPTVLPRPIELAAGDAFLLCSDGLWEGLDEEQMESALRHSQSPQEWLEQMEAAVRAQAKSYQDNFSALAV
WVADSEDGA

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 26853; Mature: 26853

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAASLSEKGGREVNEDFLGMVDMGHRGLCCVLADGAGGHGHGGLAARITVNAVLEGFGH
CCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHCCC
NPLFAPAGLASLISLAEHAVAGAQPLSISRKHMSATVVLLCIDRKTGRALWAHWGDSRLY
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCEEEEEEEECCCCCCEEEEEECCCEEE
WFRDQKVLQITEDHSVVQQLLHAGVYRNQDPRRLPNRSVLAGAIGAESQIPPTVLPRPIE
EEECCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCE
LAAGDAFLLCSDGLWEGLDEEQMESALRHSQSPQEWLEQMEAAVRAQAKSYQDNFSALAV
EECCCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
WVADSEDGA
EEECCCCCC
>Mature Secondary Structure
MMAASLSEKGGREVNEDFLGMVDMGHRGLCCVLADGAGGHGHGGLAARITVNAVLEGFGH
CCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHCCC
NPLFAPAGLASLISLAEHAVAGAQPLSISRKHMSATVVLLCIDRKTGRALWAHWGDSRLY
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCEEEEEEEECCCCCCEEEEEECCCEEE
WFRDQKVLQITEDHSVVQQLLHAGVYRNQDPRRLPNRSVLAGAIGAESQIPPTVLPRPIE
EEECCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCE
LAAGDAFLLCSDGLWEGLDEEQMESALRHSQSPQEWLEQMEAAVRAQAKSYQDNFSALAV
EECCCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
WVADSEDGA
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]