Click here to switch to the map view.

The map label for this gene is mdlA [H]

Identifier: 120610084

GI number: 120610084

Start: 1530593

End: 1531762

Strand: Direct

Name: mdlA [H]

Synonym: Aave_1397

Alternate gene names: 120610084

Gene position: 1530593-1531762 (Clockwise)

Preceding gene: 120610083

Following gene: 120610088

Centisome position: 28.59

GC content: 65.38

Gene sequence:

>1170_bases
ATGCGAATCGTCAACATCCTCGAATCCACGCGCCCCATCAAGTCCGACATCCGCAACGCCTACATCGACTTCTCGAAGAT
GACGCTCAGCCTCGTGGCCGTCGTCACCGACGTCATCCGCGATGGCCAACCCGTGATCGGCTACGGTTTCAACTCCAATG
GCCGCTACGGCCAGGGCGCGCTCATGCGCGACCGCTTCATCCCGCGCGTGCTGGAGGCCGACCCCGCCTCCCTGGTCGAT
GACACCGGCGACAACTTGTGCCCCCACAAGGTCTGGGCGCGCATGATGACCAACGAAAAACCTGGCGGCCATGGCGAGCG
CTCCGTCGCCGTCGGCACCATCGACATGGCCGTGTGGGACGCCGTGGCGAAAATAGCCAACAAGCCCCTCTACCAGTTGC
TCGCCGAGCGCTACGGCAACGGCACGCCCGCCAACCCGCGTGTGTTCGTGTACGCGGCCGGCGGCTACTACTACCCCGGC
AAGGGCCTGGACGGCTTGAAGCAAGAGATGGAGAGCTACCTCGCGCGCGGCTACTCCGTCGTCAAGATGAAGATCGGCGG
CGCGTCGCTCGCCGACGACTGCGAGCGCATCGAATCTGTCCTGAAAATCCTCGGCCCCGGCCAGCAGCTCGCCGTGGACG
CCAACGGCCGCTTCGACCTGCAAACCGCCATCGACTATGGCAAGGCGCTCTCGCAATACCCCCTGTTCTGGTACGAAGAG
GCCGGCGATCCGCTCGACTACGAACTGCAGGCCAAGCTCGGCGAGGTGTACCAGGGCCCCATGGCCACGGGCGAAAACCT
GTTCTCCATGCAGGACGCCCGCAACCTCATCCGCCACGGTGGCATGCGCCCCGACCGCGACTGGCTGCAGTTCGACTGCG
CCCTCAGCTACGGCCTCGTCGAATACCTGCGCACGCTCGACATGCTGAAAGACAACGGCTGGTCCCCCAGCCGCTGCATC
CCCCACGGCGGCCACCAGATGTCATTGGCCATCGCCGCCGGCCTGGGCCTGGGCGGCAACGAGAGCTACCCGGACCTGTT
CCAGCCGTATGGCGGGTTCCCGGACGGGGTGAAGGTGGAGAACGGGTATGTGACGCTGCCGGCGTTGCCGGGGATTGGGT
TTGAGGGGAAGTCGGACTTGATTGCGGAGATGCGGGCGTTGGCGAGTTGA

Upstream 100 bases:

>100_bases
GGGCAGGACATCGCCATCTGCGGCGGCTCCTCGCTCGCCCGCTGAACCGCTCCCTTCATCCATCCCGTTTCATCTCACAC
GGCCCGCGCCTTTGACCACC

Downstream 100 bases:

>100_bases
TGGAGGAAGGTGCTGGCGCTCGGCACGTGGTGTGTTGTTGCCCTTGGTTCCAAGTCGGTGCTGACACGCGGTTGACGCGT
ATAAATGACTGCTGACGCGT

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: MR [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MRIVNILESTRPIKSDIRNAYIDFSKMTLSLVAVVTDVIRDGQPVIGYGFNSNGRYGQGALMRDRFIPRVLEADPASLVD
DTGDNLCPHKVWARMMTNEKPGGHGERSVAVGTIDMAVWDAVAKIANKPLYQLLAERYGNGTPANPRVFVYAAGGYYYPG
KGLDGLKQEMESYLARGYSVVKMKIGGASLADDCERIESVLKILGPGQQLAVDANGRFDLQTAIDYGKALSQYPLFWYEE
AGDPLDYELQAKLGEVYQGPMATGENLFSMQDARNLIRHGGMRPDRDWLQFDCALSYGLVEYLRTLDMLKDNGWSPSRCI
PHGGHQMSLAIAAGLGLGGNESYPDLFQPYGGFPDGVKVENGYVTLPALPGIGFEGKSDLIAEMRALAS

Sequences:

>Translated_389_residues
MRIVNILESTRPIKSDIRNAYIDFSKMTLSLVAVVTDVIRDGQPVIGYGFNSNGRYGQGALMRDRFIPRVLEADPASLVD
DTGDNLCPHKVWARMMTNEKPGGHGERSVAVGTIDMAVWDAVAKIANKPLYQLLAERYGNGTPANPRVFVYAAGGYYYPG
KGLDGLKQEMESYLARGYSVVKMKIGGASLADDCERIESVLKILGPGQQLAVDANGRFDLQTAIDYGKALSQYPLFWYEE
AGDPLDYELQAKLGEVYQGPMATGENLFSMQDARNLIRHGGMRPDRDWLQFDCALSYGLVEYLRTLDMLKDNGWSPSRCI
PHGGHQMSLAIAAGLGLGGNESYPDLFQPYGGFPDGVKVENGYVTLPALPGIGFEGKSDLIAEMRALAS
>Mature_389_residues
MRIVNILESTRPIKSDIRNAYIDFSKMTLSLVAVVTDVIRDGQPVIGYGFNSNGRYGQGALMRDRFIPRVLEADPASLVD
DTGDNLCPHKVWARMMTNEKPGGHGERSVAVGTIDMAVWDAVAKIANKPLYQLLAERYGNGTPANPRVFVYAAGGYYYPG
KGLDGLKQEMESYLARGYSVVKMKIGGASLADDCERIESVLKILGPGQQLAVDANGRFDLQTAIDYGKALSQYPLFWYEE
AGDPLDYELQAKLGEVYQGPMATGENLFSMQDARNLIRHGGMRPDRDWLQFDCALSYGLVEYLRTLDMLKDNGWSPSRCI
PHGGHQMSLAIAAGLGLGGNESYPDLFQPYGGFPDGVKVENGYVTLPALPGIGFEGKSDLIAEMRALAS

Specific function: D-galactonate degradation; first step. D-galactonate degradation; third step. [C]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR015654
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =5.1.2.2 [H]

Molecular weight: Translated: 42572; Mature: 42572

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVNILESTRPIKSDIRNAYIDFSKMTLSLVAVVTDVIRDGQPVIGYGFNSNGRYGQGA
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
LMRDRFIPRVLEADPASLVDDTGDNLCPHKVWARMMTNEKPGGHGERSVAVGTIDMAVWD
HHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHH
AVAKIANKPLYQLLAERYGNGTPANPRVFVYAAGGYYYPGKGLDGLKQEMESYLARGYSV
HHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCEECCCCCHHHHHHHHHHHHHCCEEE
VKMKIGGASLADDCERIESVLKILGPGQQLAVDANGRFDLQTAIDYGKALSQYPLFWYEE
EEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHHHHHCCCEEEEC
AGDPLDYELQAKLGEVYQGPMATGENLFSMQDARNLIRHGGMRPDRDWLQFDCALSYGLV
CCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
EYLRTLDMLKDNGWSPSRCIPHGGHQMSLAIAAGLGLGGNESYPDLFQPYGGFPDGVKVE
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHCCCCCCCCEEEC
NGYVTLPALPGIGFEGKSDLIAEMRALAS
CCEEEECCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRIVNILESTRPIKSDIRNAYIDFSKMTLSLVAVVTDVIRDGQPVIGYGFNSNGRYGQGA
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
LMRDRFIPRVLEADPASLVDDTGDNLCPHKVWARMMTNEKPGGHGERSVAVGTIDMAVWD
HHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHH
AVAKIANKPLYQLLAERYGNGTPANPRVFVYAAGGYYYPGKGLDGLKQEMESYLARGYSV
HHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCEECCCCCHHHHHHHHHHHHHCCEEE
VKMKIGGASLADDCERIESVLKILGPGQQLAVDANGRFDLQTAIDYGKALSQYPLFWYEE
EEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHHHHHCCCEEEEC
AGDPLDYELQAKLGEVYQGPMATGENLFSMQDARNLIRHGGMRPDRDWLQFDCALSYGLV
CCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
EYLRTLDMLKDNGWSPSRCIPHGGHQMSLAIAAGLGLGGNESYPDLFQPYGGFPDGVKVE
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHCCCCCCCCEEEC
NGYVTLPALPGIGFEGKSDLIAEMRALAS
CCEEEECCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2831968; 2271624; 2215699; 1909893; 1892834; 7893689; 7893690 [H]