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The map label for this gene is fabG [H]

Identifier: 120610083

GI number: 120610083

Start: 1529767

End: 1530537

Strand: Direct

Name: fabG [H]

Synonym: Aave_1396

Alternate gene names: 120610083

Gene position: 1529767-1530537 (Clockwise)

Preceding gene: 120610082

Following gene: 120610084

Centisome position: 28.58

GC content: 76.78

Gene sequence:

>771_bases
GTGCCCCATGCCGTCGTCACCGGCAGCAGCAGCGGCATCGGCCGCGCCATCGCCGAATCGCTGCTCGCCACCGGCTGGCG
CGTGACGGGGCTCGACATCGCGCCGCCCGCCATCGCGCACCCGGCCTTCGCGCACCTGCCCGTGGACCTGGCCGACGGCG
AGGCCATCGCCCGCGCCGCGGCGGGGTTGCTGGAGGCGGATCCGCGCGAAATCGTGGCGCCGAACACATCGGGCCACGCC
AGCTCCCAGCCGCCGAATTCCCCGCCCGCGCCCCAGGCCCCCGATGCCTTGGTGCACGCTGCAGGCGTGTTGCGCGTCGG
CCCGCTCGGCCAGCTGGACCATGCCGGCGGCGCACTCATGTGGCGCCTGCACGTCGATGCGGCCACGCGCCTTGCTGATG
CCCTCGTGCCCGCCATGGCCGCACGCGGGCGGGGCCGCGTCGTCTTCATCGGCAGCCGCGTGGCCCAGGGCATGCCCGGG
CGCGGCCAGTACGCCGCCACCAAGGCCGCGCTCATCGCGCTCGCGCGCAGCTGGGCGGCCGAAGTGGCGGGGCAGGGCGT
CACCGTCAACGTCGTCTCGCCCGCCGCCACCGCCACCGGCATGCTCGCCGACCCGGCCCGCGCCGGCAGCGCGCCGCGCC
TGCCGCCCATCGGCCGCCTCATCGACCCCGCGGAAATCGCCGCGCTCACGGGCTACCTGCTCTCGCCCGCGGCCGCCGCC
ATCACCGGGCAGGACATCGCCATCTGCGGCGGCTCCTCGCTCGCCCGCTGA

Upstream 100 bases:

>100_bases
GATTTCGCCAGGTTCCAGCGCGAGGACATGGAGCGCTCCCAGAAGATCGTGACCGAGGGCCGCATCCGTGCCGAGTGACG
CGCTTCCAGCGGCCCGCCCC

Downstream 100 bases:

>100_bases
ACCGCTCCCTTCATCCATCCCGTTTCATCTCACACGGCCCGCGCCTTTGACCACCATGCGAATCGTCAACATCCTCGAAT
CCACGCGCCCCATCAAGTCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MPHAVVTGSSSGIGRAIAESLLATGWRVTGLDIAPPAIAHPAFAHLPVDLADGEAIARAAAGLLEADPREIVAPNTSGHA
SSQPPNSPPAPQAPDALVHAAGVLRVGPLGQLDHAGGALMWRLHVDAATRLADALVPAMAARGRGRVVFIGSRVAQGMPG
RGQYAATKAALIALARSWAAEVAGQGVTVNVVSPAATATGMLADPARAGSAPRLPPIGRLIDPAEIAALTGYLLSPAAAA
ITGQDIAICGGSSLAR

Sequences:

>Translated_256_residues
MPHAVVTGSSSGIGRAIAESLLATGWRVTGLDIAPPAIAHPAFAHLPVDLADGEAIARAAAGLLEADPREIVAPNTSGHA
SSQPPNSPPAPQAPDALVHAAGVLRVGPLGQLDHAGGALMWRLHVDAATRLADALVPAMAARGRGRVVFIGSRVAQGMPG
RGQYAATKAALIALARSWAAEVAGQGVTVNVVSPAATATGMLADPARAGSAPRLPPIGRLIDPAEIAALTGYLLSPAAAA
ITGQDIAICGGSSLAR
>Mature_255_residues
PHAVVTGSSSGIGRAIAESLLATGWRVTGLDIAPPAIAHPAFAHLPVDLADGEAIARAAAGLLEADPREIVAPNTSGHAS
SQPPNSPPAPQAPDALVHAAGVLRVGPLGQLDHAGGALMWRLHVDAATRLADALVPAMAARGRGRVVFIGSRVAQGMPGR
GQYAATKAALIALARSWAAEVAGQGVTVNVVSPAATATGMLADPARAGSAPRLPPIGRLIDPAEIAALTGYLLSPAAAAI
TGQDIAICGGSSLAR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=170, Percent_Identity=30, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=271, Percent_Identity=27.6752767527675, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=35.0393700787402, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=33.587786259542, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082100, Length=265, Percent_Identity=30.188679245283, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=267, Percent_Identity=26.9662921348315, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=262, Percent_Identity=25.9541984732824, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639444, Length=261, Percent_Identity=27.2030651340996, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643142, Length=166, Percent_Identity=29.5180722891566, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25436; Mature: 25305

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHAVVTGSSSGIGRAIAESLLATGWRVTGLDIAPPAIAHPAFAHLPVDLADGEAIARAA
CCCEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHCCEECCCCHHHHHHH
AGLLEADPREIVAPNTSGHASSQPPNSPPAPQAPDALVHAAGVLRVGPLGQLDHAGGALM
HHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCEEECCCCCCCCCCCEEE
WRLHVDAATRLADALVPAMAARGRGRVVFIGSRVAQGMPGRGQYAATKAALIALARSWAA
EEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EVAGQGVTVNVVSPAATATGMLADPARAGSAPRLPPIGRLIDPAEIAALTGYLLSPAAAA
HHCCCCEEEEEECCCCHHCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
ITGQDIAICGGSSLAR
CCCCCEEEECCCCCCC
>Mature Secondary Structure 
PHAVVTGSSSGIGRAIAESLLATGWRVTGLDIAPPAIAHPAFAHLPVDLADGEAIARAA
CCEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHCCEECCCCHHHHHHH
AGLLEADPREIVAPNTSGHASSQPPNSPPAPQAPDALVHAAGVLRVGPLGQLDHAGGALM
HHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCEEECCCCCCCCCCCEEE
WRLHVDAATRLADALVPAMAARGRGRVVFIGSRVAQGMPGRGQYAATKAALIALARSWAA
EEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EVAGQGVTVNVVSPAATATGMLADPARAGSAPRLPPIGRLIDPAEIAALTGYLLSPAAAA
HHCCCCEEEEEECCCCHHCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
ITGQDIAICGGSSLAR
CCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]