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The map label for this gene is ahcY [H]

Identifier: 120610044

GI number: 120610044

Start: 1484890

End: 1486032

Strand: Direct

Name: ahcY [H]

Synonym: Aave_1357

Alternate gene names: 120610044

Gene position: 1484890-1486032 (Clockwise)

Preceding gene: 120610041

Following gene: 120610045

Centisome position: 27.74

GC content: 64.48

Gene sequence:

>1143_bases
ATGGATTCCAAAGCATTCTTCCAGGCGGTTCTGGACAGCAGCGTTCCCAGGCGGGCGGGCAAGCTGGTCCTCGTGACCCA
CATCGTTCCCGGGAGCGAGAATTTCGTCCTCGGCATCCACGAACGCCTGCCCCTGGCGGCGGTCATTCCCAAGCCCAGTT
CCCTGCACGAGCCCACCTGCCGCGTGATCGAGGAGCATGTACCGGTGATCCACTACACGCGGGACAGGATCCAGCAGAAC
GCGCTCGGCTTCATTGCGCACCTGCGCAGCCTGATCGGGGAGGAGCCTTTCGCGGCCATCGATACCGGGGGCTATTTCTC
GAGCATCCTGGCCGCCCTGAAAAAGGCATTTCCCTCGCAACTGGTGGGCATCGTCGAGGACACCGAGAACGGACACCAGA
AGTACGACGCCGCACTGCGCAGCATCCGGGCGGGCGGGGGCGCCATGTTTCCCTGTCCCGTCATGTCCGTGGCCAGGAGC
AAGCTCAAGGAGCCGGAGGATTTCCTGGTCGGCCAGGCCATCACGTTTTCCGCCGAGGCCCTGCTGCGGGAACTGGGGAA
CATCCTGACCGGCCGCAGGGCGCTGGTACTGGGCTACGGGAAGATCGGATCGAGCATTGCCCGGCACCTGCATGCCAAAG
GCGTTCGCGTCGACGTGTACGACACGAACCCGATCCGCCAGGTGCTGGCCCTGGCGCACGGCTACCACACCGGGCCGAAG
CACGAACTTTTGAGGACGGCGGAACTCATTTTCTGCGCGACCGGCAACCGGTCCATCGGAACGTCCGACCTGGGCGCCAT
CCGGCGCGATGCCTACATCTTCACCGCCACGTCGGCCGACGACGAGATCGAGAACCACCAGGACATGATCGCCAGCGCGA
GCCCCGGCGGGCACAGGCACGTGCTGCAGGTGAACGCGCAGGGCAACCAGTTCTTCCTCTGCAACGAGGGCAAGTCGGCC
AATTTCATGCACGGAGGCGTGGTCGGGCCCTTCATCGACCTCGTGCAGGCCGAGCTGCTCTTCGCGCTCTCCAGGATCGG
CGACGCCCCCCGGGACCGGGTGGTGGAACTGGGCGACGATGCGAAGAGATTCATTTCCGAGCTGTGGATCACGCGCTTTT
CTCGACAGGGCATGGTCCATTGA

Upstream 100 bases:

>100_bases
GCGCGGAAAATCACCCATGCCAGTGGACGGAGATTTCCGCGGTGTCCGGCGAAGGTTTGGCCAGAAGATTGCCCGCCACG
GCCTGGCCGCCTGATCCGCC

Downstream 100 bases:

>100_bases
ACAACTTTTCCGCGCAGGAGGTCATGGCGGTGGCGTGGGCCTCCGCCCTGTGCAGGGCCGTCCTGAACCTGATAGACCGG
CAGCAGATCGGACGCAAGGG

Product: adenosylhomocysteinase

Products: NA

Alternate protein names: S-adenosyl-L-homocysteine hydrolase; AdoHcyase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDSKAFFQAVLDSSVPRRAGKLVLVTHIVPGSENFVLGIHERLPLAAVIPKPSSLHEPTCRVIEEHVPVIHYTRDRIQQN
ALGFIAHLRSLIGEEPFAAIDTGGYFSSILAALKKAFPSQLVGIVEDTENGHQKYDAALRSIRAGGGAMFPCPVMSVARS
KLKEPEDFLVGQAITFSAEALLRELGNILTGRRALVLGYGKIGSSIARHLHAKGVRVDVYDTNPIRQVLALAHGYHTGPK
HELLRTAELIFCATGNRSIGTSDLGAIRRDAYIFTATSADDEIENHQDMIASASPGGHRHVLQVNAQGNQFFLCNEGKSA
NFMHGGVVGPFIDLVQAELLFALSRIGDAPRDRVVELGDDAKRFISELWITRFSRQGMVH

Sequences:

>Translated_380_residues
MDSKAFFQAVLDSSVPRRAGKLVLVTHIVPGSENFVLGIHERLPLAAVIPKPSSLHEPTCRVIEEHVPVIHYTRDRIQQN
ALGFIAHLRSLIGEEPFAAIDTGGYFSSILAALKKAFPSQLVGIVEDTENGHQKYDAALRSIRAGGGAMFPCPVMSVARS
KLKEPEDFLVGQAITFSAEALLRELGNILTGRRALVLGYGKIGSSIARHLHAKGVRVDVYDTNPIRQVLALAHGYHTGPK
HELLRTAELIFCATGNRSIGTSDLGAIRRDAYIFTATSADDEIENHQDMIASASPGGHRHVLQVNAQGNQFFLCNEGKSA
NFMHGGVVGPFIDLVQAELLFALSRIGDAPRDRVVELGDDAKRFISELWITRFSRQGMVH
>Mature_380_residues
MDSKAFFQAVLDSSVPRRAGKLVLVTHIVPGSENFVLGIHERLPLAAVIPKPSSLHEPTCRVIEEHVPVIHYTRDRIQQN
ALGFIAHLRSLIGEEPFAAIDTGGYFSSILAALKKAFPSQLVGIVEDTENGHQKYDAALRSIRAGGGAMFPCPVMSVARS
KLKEPEDFLVGQAITFSAEALLRELGNILTGRRALVLGYGKIGSSIARHLHAKGVRVDVYDTNPIRQVLALAHGYHTGPK
HELLRTAELIFCATGNRSIGTSDLGAIRRDAYIFTATSADDEIENHQDMIASASPGGHRHVLQVNAQGNQFFLCNEGKSA
NFMHGGVVGPFIDLVQAELLFALSRIGDAPRDRVVELGDDAKRFISELWITRFSRQGMVH

Specific function: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine [H]

COG id: COG0499

COG function: function code H; S-adenosylhomocysteine hydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosylhomocysteinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000043
- InterPro:   IPR015878
- InterPro:   IPR020082 [H]

Pfam domain/function: PF05221 AdoHcyase; PF00670 AdoHcyase_NAD [H]

EC number: =3.3.1.1 [H]

Molecular weight: Translated: 41451; Mature: 41451

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSKAFFQAVLDSSVPRRAGKLVLVTHIVPGSENFVLGIHERLPLAAVIPKPSSLHEPTC
CCHHHHHHHHHHCCCCHHCCCEEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCHHH
RVIEEHVPVIHYTRDRIQQNALGFIAHLRSLIGEEPFAAIDTGGYFSSILAALKKAFPSQ
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHH
LVGIVEDTENGHQKYDAALRSIRAGGGAMFPCPVMSVARSKLKEPEDFLVGQAITFSAEA
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHH
LLRELGNILTGRRALVLGYGKIGSSIARHLHAKGVRVDVYDTNPIRQVLALAHGYHTGPK
HHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCH
HELLRTAELIFCATGNRSIGTSDLGAIRRDAYIFTATSADDEIENHQDMIASASPGGHRH
HHHHHHEEEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCCEE
VLQVNAQGNQFFLCNEGKSANFMHGGVVGPFIDLVQAELLFALSRIGDAPRDRVVELGDD
EEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCH
AKRFISELWITRFSRQGMVH
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDSKAFFQAVLDSSVPRRAGKLVLVTHIVPGSENFVLGIHERLPLAAVIPKPSSLHEPTC
CCHHHHHHHHHHCCCCHHCCCEEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCHHH
RVIEEHVPVIHYTRDRIQQNALGFIAHLRSLIGEEPFAAIDTGGYFSSILAALKKAFPSQ
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHH
LVGIVEDTENGHQKYDAALRSIRAGGGAMFPCPVMSVARSKLKEPEDFLVGQAITFSAEA
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHH
LLRELGNILTGRRALVLGYGKIGSSIARHLHAKGVRVDVYDTNPIRQVLALAHGYHTGPK
HHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCH
HELLRTAELIFCATGNRSIGTSDLGAIRRDAYIFTATSADDEIENHQDMIASASPGGHRH
HHHHHHEEEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCCEE
VLQVNAQGNQFFLCNEGKSANFMHGGVVGPFIDLVQAELLFALSRIGDAPRDRVVELGDD
EEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCH
AKRFISELWITRFSRQGMVH
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9440516; 10360571 [H]