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The map label for this gene is pdxY [H]

Identifier: 120610032

GI number: 120610032

Start: 1474007

End: 1474948

Strand: Reverse

Name: pdxY [H]

Synonym: Aave_1345

Alternate gene names: 120610032

Gene position: 1474948-1474007 (Counterclockwise)

Preceding gene: 120610033

Following gene: 120610026

Centisome position: 27.55

GC content: 73.46

Gene sequence:

>942_bases
GTGAGCGCCACCGCAGCCCCTTCCGCCAACCCGCCTGCACCGGCCTCGGCCGGGGAGCCGCCGCTGGTGCTCTCCATCCA
GTCGCATGTCGCCTTCGGGCACGTGGGCAACGACGCGGCCATGCTGCCGCTGCAACTGCTGGGCATCCAGCCGGTGGCCG
TGCATACGGTGCAGTTCTCCAACCACACGGGCTACGGCGAGTTCAAGGGGCAGGTCTTCCCGCCCGCGCACATCGGCGAC
GTGCTCGATGGCCTGCGTGCGCGCGGCGTGCTGGCACGCTGCACGGCGGTGCTCTCGGGCTACCTGGGCGATGCCGGCGT
GGGCGAGGCCATCCTGGCCGCGGTGCAGGAGATCCGGGCCGTTCGCCCGGGCCTGCGCTACCTGTGCGATCCGGTGATGG
GCGACGTGGGCCGCGGCGTGTTCGTGCGCCCGGGCATCCCGGAATTCCTGCGCCGCCGCGCGCTGGCGCAGGCCAGCATC
ATCACCCCCAACCAGTACGAATTCGAGTTGCTGCACGGCGCGCCGCTGGCCTCGGTGGACGAGGCGGTGGCCGCCGCGCG
CGCGCTGCTGGGCGACGCCGCCGGAACAGGCCCTTCGCTCATCGTGGTGACCAGCCTGCGCACGCCGGACCTGCCGGACG
ACCGGCTGGCCACGCTGGCCGTCACGGAGGAGGCCGCCTGGCTGGTGCGCACGCCGTTCATCGACCTGCAGCCCCTGCCC
AATGGCATGGGCGACGTGTTCTCGGCCGTTCTGCTGGGCCACCTGCTGCGCGGCGCATCGACGCCGGACGCGGTGTCGAG
CGCGGTCAGCAGCCTGTACGCACTGGTGTCGCGCACCGCGCCGGGCCAGCGCGACCTGCCCCTGGTGGCCTGCCGCGAGC
AGATCGCGCAGCCGTCGGAGCGTTTCGCCGCCGAGATGGTGGGCGCCCCGACGCGGCCCTGA

Upstream 100 bases:

>100_bases
GCAAGCACGCGCGCAGCGCCTTCGGCGTGGCGCAGATCCCCATGGGTGCCTGCGTGGAGATCGAGCTGATCGCCGAACTG
GCCTGAGCGCCGAGGACGCC

Downstream 100 bases:

>100_bases
GACAGAGTTCCGGCCGCGGCCCGGATCAGGCCGCCAGCGTGCGCGGCCCGCCCCGCACGGGCTGCTGCAGCGCCGCGCCG
GCAGCCCCCGGCAGGGCGCG

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSATAAPSANPPAPASAGEPPLVLSIQSHVAFGHVGNDAAMLPLQLLGIQPVAVHTVQFSNHTGYGEFKGQVFPPAHIGD
VLDGLRARGVLARCTAVLSGYLGDAGVGEAILAAVQEIRAVRPGLRYLCDPVMGDVGRGVFVRPGIPEFLRRRALAQASI
ITPNQYEFELLHGAPLASVDEAVAAARALLGDAAGTGPSLIVVTSLRTPDLPDDRLATLAVTEEAAWLVRTPFIDLQPLP
NGMGDVFSAVLLGHLLRGASTPDAVSSAVSSLYALVSRTAPGQRDLPLVACREQIAQPSERFAAEMVGAPTRP

Sequences:

>Translated_313_residues
MSATAAPSANPPAPASAGEPPLVLSIQSHVAFGHVGNDAAMLPLQLLGIQPVAVHTVQFSNHTGYGEFKGQVFPPAHIGD
VLDGLRARGVLARCTAVLSGYLGDAGVGEAILAAVQEIRAVRPGLRYLCDPVMGDVGRGVFVRPGIPEFLRRRALAQASI
ITPNQYEFELLHGAPLASVDEAVAAARALLGDAAGTGPSLIVVTSLRTPDLPDDRLATLAVTEEAAWLVRTPFIDLQPLP
NGMGDVFSAVLLGHLLRGASTPDAVSSAVSSLYALVSRTAPGQRDLPLVACREQIAQPSERFAAEMVGAPTRP
>Mature_312_residues
SATAAPSANPPAPASAGEPPLVLSIQSHVAFGHVGNDAAMLPLQLLGIQPVAVHTVQFSNHTGYGEFKGQVFPPAHIGDV
LDGLRARGVLARCTAVLSGYLGDAGVGEAILAAVQEIRAVRPGLRYLCDPVMGDVGRGVFVRPGIPEFLRRRALAQASII
TPNQYEFELLHGAPLASVDEAVAAARALLGDAAGTGPSLIVVTSLRTPDLPDDRLATLAVTEEAAWLVRTPFIDLQPLPN
GMGDVFSAVLLGHLLRGASTPDAVSSAVSSLYALVSRTAPGQRDLPLVACREQIAQPSERFAAEMVGAPTRP

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=310, Percent_Identity=33.2258064516129, Blast_Score=144, Evalue=8e-35,
Organism=Escherichia coli, GI1787924, Length=284, Percent_Identity=41.1971830985916, Blast_Score=217, Evalue=9e-58,
Organism=Escherichia coli, GI1788758, Length=248, Percent_Identity=33.0645161290323, Blast_Score=124, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17507759, Length=260, Percent_Identity=31.5384615384615, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17507757, Length=270, Percent_Identity=30.3703703703704, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320806, Length=249, Percent_Identity=36.5461847389558, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324354, Length=297, Percent_Identity=29.96632996633, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI45553007, Length=305, Percent_Identity=32.1311475409836, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 32529; Mature: 32397

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATAAPSANPPAPASAGEPPLVLSIQSHVAFGHVGNDAAMLPLQLLGIQPVAVHTVQFS
CCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCHHHHHHHHHCCCCEEEEEEEEC
NHTGYGEFKGQVFPPAHIGDVLDGLRARGVLARCTAVLSGYLGDAGVGEAILAAVQEIRA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VRPGLRYLCDPVMGDVGRGVFVRPGIPEFLRRRALAQASIITPNQYEFELLHGAPLASVD
HHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHH
EAVAAARALLGDAAGTGPSLIVVTSLRTPDLPDDRLATLAVTEEAAWLVRTPFIDLQPLP
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCEEEECCCEECCCCC
NGMGDVFSAVLLGHLLRGASTPDAVSSAVSSLYALVSRTAPGQRDLPLVACREQIAQPSE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHH
RFAAEMVGAPTRP
HHHHHHHCCCCCC
>Mature Secondary Structure 
SATAAPSANPPAPASAGEPPLVLSIQSHVAFGHVGNDAAMLPLQLLGIQPVAVHTVQFS
CCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCHHHHHHHHHCCCCEEEEEEEEC
NHTGYGEFKGQVFPPAHIGDVLDGLRARGVLARCTAVLSGYLGDAGVGEAILAAVQEIRA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VRPGLRYLCDPVMGDVGRGVFVRPGIPEFLRRRALAQASIITPNQYEFELLHGAPLASVD
HHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHH
EAVAAARALLGDAAGTGPSLIVVTSLRTPDLPDDRLATLAVTEEAAWLVRTPFIDLQPLP
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCEEEECCCEECCCCC
NGMGDVFSAVLLGHLLRGASTPDAVSSAVSSLYALVSRTAPGQRDLPLVACREQIAQPSE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHH
RFAAEMVGAPTRP
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA