Click here to switch to the map view.

The map label for this gene is nuoG [H]

Identifier: 120609956

GI number: 120609956

Start: 1392600

End: 1394750

Strand: Direct

Name: nuoG [H]

Synonym: Aave_1269

Alternate gene names: 120609956

Gene position: 1392600-1394750 (Clockwise)

Preceding gene: 120609955

Following gene: 120609957

Centisome position: 26.02

GC content: 69.08

Gene sequence:

>2151_bases
ATGGTTGAAATCGAACTCGACGGGAAGAAGGTGGAAGTCGCCGAAGGCTGCATGGTGATGCATGCGGCCGAGAAGGCGGG
CACCTACATCCCTCATTTCTGCTATCACAAGAAGCTCTCCATCGCCGCCAACTGCCGCATGTGCCTGGTGGACGTGGAGA
AGGCTCCCAAGCCGATGCCCGCCTGCGCCACGCCCGTGACGCAGGGCATGATCGTGCGCACCAAGAGCGACAAGGCCATC
AAGGCCCAGCAGTCGGTCATGGAATTCCTGCTGATCAACCATCCGCTGGACTGCCCGATCTGCGACCAGGGCGGCGAGTG
CCAGCTGCAGGACCTGGCCGTGGGCTATGGCGGCTCCTCCTCGCGCTACGAGGAAGAAAAGCGCGTGGTCTTCCACAAGG
ACGTCGGCCCGCTGATCTCCATGGAGGAGATGACCCGCTGCATCCACTGCACCCGCTGCGTGCGCTTCGGCCAGGAAGTG
GCCGGCGTGATGGAGCTGGGCATGATCCACCGCGGCGAGCATTCCGAGATCACCACCGTGGTGGGCGATACCGTGGATTC
CGAGCTGTCGGGCAACATGATCGACATCTGCCCCGTGGGCGCGCTCACGAGCAAGCCGTTCCGCTACAGCGCCCGCACGT
GGGAGCTGTCGCGCCGCAAGTCGGTCAGCCCGCATGATTCCACGGGCGCCAACCTGATCGTCCAGGTGAAGAACCACAAG
GTCATGCGCGTCGTCCCGTTCGAGAACGAGGACGTGAACGAGTGCTGGATCGCCGACCGCGACCGCTTCTCGTACGAAGC
GCTGAACGGCCCCGACCGCCTGACGAAGCCCATGCTCAAGCAGGGCGGCCAGTGGAAGGAAGTGGACTGGCAGACGGCCC
TCGAATACGTGGCCAACGGCCTGCGCGGCATCCAGTCCGAGCACGGTGCCCAGAGCATCGGCGCGCTGGTCAGCCCGCAC
AGCACGCTGGAAGAACTGCACCTGGCCACGCTGCTGGTGCGCGGCCTGGGCAGCGACAACATCGACTACCGCCTGCGCAA
CGCGGAATTCACCGCGCCGGAAGGCGTCCGCTGGCTGGGCATGCCCATCGCGGCGCTGTCCACGCTGCAGTCCGTGCTGG
TCGTGGGCTCCAACCTGCGCAAGGAACATCCGCTGTTCGCGCAGCGCATCCGCCAGGCGGCCCGCAAGGGCTGCGCCGTG
AGCGCGCTGAATTCCGTGGCCTACGACTGGGCCATGCCGATGGCGCAATCCATCGTCGCGCCTGCGGGTGAGTGGGCCGC
CGCGCTGGCCGACATCGCTGCCGCCGTCGCCCAGGAGCGTGGCGTGGCCGCGCCCGTGGCGTCCGGCCGTGTGACCGATG
CGGCCCTGGCCGTGGCGCGTTCGCTCGCGTCCGGCGAAGGCCGTGCCGTGCTGCTCGGCAATGCCGCGGCGCACCATGCC
CAGGCATCGTCGCTGCTGGCGCTGGCCCAGTGGATCGGCGCGCAGACCGGCGCGGTGGTCGGCTACCTGACCGAAGCCGC
CAATACCGTCGGCGCGCAGTTCGTGAGGGCGCAGCCCCGGCAGGGCGGGCTCGATGCCGGCCGCATGCTGGCCGGCGGCC
TGAAGGCCGCGCTGCTGCTCAATACCGAGCCGGTGCACGATTCCGCCGCTGGTGCCCGCGCCGCACAGGCGCTCGCGCAG
GCCGAGATGGTCGTGACGCTGAGCCCGTTCAAGACCAACCTGGAATTCAGCGACGTGCTGCTGCCCATCGCCCCGTTCAC
CGAAACCTCCGGCAGCTTCGTGAATGCCGAAGGCCGCCTGCAGAGCTTCCACGCCGTGGTCAAGCCGCTGGGCGACGCCC
GTCCGGCCTGGAAGGTGCTGCGTGTGCTCGGCAACCTGCTGGGCTTGCAGGGCATCGGCTTCGAGACCTCGCAGGAGGTG
CTGGCCCACGCCGTGGGCGCCACCGGCGCCGAACTGCCGACGCACCTGCCGGCCGACCGCCTTGCCAACACCACGTCCGC
GGCACCCGCCGTGCCGGCCGCCGCAGGCACGCCGGAGCCCGTGGTCGCCGCCATCTACCAGCTCGACAGCCTCGTGCGCC
GCGCGCCCTCGCTGCAGCTGACGGCCGACGGCCGCCAGGCCACCGTCGCCGTGGAAGGAGCCGCAGCATGA

Upstream 100 bases:

>100_bases
GCGGGCGATGATCAAGCACTTCCGTCCGGAATTCGAGGCGCTGATCCGCAACAAGACGAGCCCCCAGGCTCCGGCCTCCG
CCTGATCGCGAGAAACGCAT

Downstream 100 bases:

>100_bases
TCGACGCGCTCTACAACGGCGGGCTGAACCTCGTCGCGCAGTCCTGGTGGACGGGCGCCGTGTGGCCCGTGCTCTGGAAC
CTGCTCAAGATCGTCGCCAT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MVEIELDGKKVEVAEGCMVMHAAEKAGTYIPHFCYHKKLSIAANCRMCLVDVEKAPKPMPACATPVTQGMIVRTKSDKAI
KAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGSSSRYEEEKRVVFHKDVGPLISMEEMTRCIHCTRCVRFGQEV
AGVMELGMIHRGEHSEITTVVGDTVDSELSGNMIDICPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
VMRVVPFENEDVNECWIADRDRFSYEALNGPDRLTKPMLKQGGQWKEVDWQTALEYVANGLRGIQSEHGAQSIGALVSPH
STLEELHLATLLVRGLGSDNIDYRLRNAEFTAPEGVRWLGMPIAALSTLQSVLVVGSNLRKEHPLFAQRIRQAARKGCAV
SALNSVAYDWAMPMAQSIVAPAGEWAAALADIAAAVAQERGVAAPVASGRVTDAALAVARSLASGEGRAVLLGNAAAHHA
QASSLLALAQWIGAQTGAVVGYLTEAANTVGAQFVRAQPRQGGLDAGRMLAGGLKAALLLNTEPVHDSAAGARAAQALAQ
AEMVVTLSPFKTNLEFSDVLLPIAPFTETSGSFVNAEGRLQSFHAVVKPLGDARPAWKVLRVLGNLLGLQGIGFETSQEV
LAHAVGATGAELPTHLPADRLANTTSAAPAVPAAAGTPEPVVAAIYQLDSLVRRAPSLQLTADGRQATVAVEGAAA

Sequences:

>Translated_716_residues
MVEIELDGKKVEVAEGCMVMHAAEKAGTYIPHFCYHKKLSIAANCRMCLVDVEKAPKPMPACATPVTQGMIVRTKSDKAI
KAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGSSSRYEEEKRVVFHKDVGPLISMEEMTRCIHCTRCVRFGQEV
AGVMELGMIHRGEHSEITTVVGDTVDSELSGNMIDICPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
VMRVVPFENEDVNECWIADRDRFSYEALNGPDRLTKPMLKQGGQWKEVDWQTALEYVANGLRGIQSEHGAQSIGALVSPH
STLEELHLATLLVRGLGSDNIDYRLRNAEFTAPEGVRWLGMPIAALSTLQSVLVVGSNLRKEHPLFAQRIRQAARKGCAV
SALNSVAYDWAMPMAQSIVAPAGEWAAALADIAAAVAQERGVAAPVASGRVTDAALAVARSLASGEGRAVLLGNAAAHHA
QASSLLALAQWIGAQTGAVVGYLTEAANTVGAQFVRAQPRQGGLDAGRMLAGGLKAALLLNTEPVHDSAAGARAAQALAQ
AEMVVTLSPFKTNLEFSDVLLPIAPFTETSGSFVNAEGRLQSFHAVVKPLGDARPAWKVLRVLGNLLGLQGIGFETSQEV
LAHAVGATGAELPTHLPADRLANTTSAAPAVPAAAGTPEPVVAAIYQLDSLVRRAPSLQLTADGRQATVAVEGAAA
>Mature_716_residues
MVEIELDGKKVEVAEGCMVMHAAEKAGTYIPHFCYHKKLSIAANCRMCLVDVEKAPKPMPACATPVTQGMIVRTKSDKAI
KAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGSSSRYEEEKRVVFHKDVGPLISMEEMTRCIHCTRCVRFGQEV
AGVMELGMIHRGEHSEITTVVGDTVDSELSGNMIDICPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
VMRVVPFENEDVNECWIADRDRFSYEALNGPDRLTKPMLKQGGQWKEVDWQTALEYVANGLRGIQSEHGAQSIGALVSPH
STLEELHLATLLVRGLGSDNIDYRLRNAEFTAPEGVRWLGMPIAALSTLQSVLVVGSNLRKEHPLFAQRIRQAARKGCAV
SALNSVAYDWAMPMAQSIVAPAGEWAAALADIAAAVAQERGVAAPVASGRVTDAALAVARSLASGEGRAVLLGNAAAHHA
QASSLLALAQWIGAQTGAVVGYLTEAANTVGAQFVRAQPRQGGLDAGRMLAGGLKAALLLNTEPVHDSAAGARAAQALAQ
AEMVVTLSPFKTNLEFSDVLLPIAPFTETSGSFVNAEGRLQSFHAVVKPLGDARPAWKVLRVLGNLLGLQGIGFETSQEV
LAHAVGATGAELPTHLPADRLANTTSAAPAVPAAAGTPEPVVAAIYQLDSLVRRAPSLQLTADGRQATVAVEGAAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=654, Percent_Identity=37.0030581039755, Blast_Score=379, Evalue=1e-105,
Organism=Escherichia coli, GI145693161, Length=714, Percent_Identity=28.4313725490196, Blast_Score=224, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17565758, Length=653, Percent_Identity=37.2128637059724, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI32566231, Length=626, Percent_Identity=37.220447284345, Blast_Score=344, Evalue=7e-95,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=51.1904761904762, Blast_Score=268, Evalue=8e-72,
Organism=Drosophila melanogaster, GI24640559, Length=655, Percent_Identity=37.7099236641221, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24640557, Length=655, Percent_Identity=37.7099236641221, Blast_Score=365, Evalue=1e-101,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 76096; Mature: 76096

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEIELDGKKVEVAEGCMVMHAAEKAGTYIPHFCYHKKLSIAANCRMCLVDVEKAPKPMP
CEEEEECCCEEEHHHCCCEEEEHHHCCCCCCHHHHHCCEEEECCCEEEEEECCCCCCCCC
ACATPVTQGMIVRTKSDKAIKAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGSS
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCC
SRYEEEKRVVFHKDVGPLISMEEMTRCIHCTRCVRFGQEVAGVMELGMIHRGEHSEITTV
CCCHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VGDTVDSELSGNMIDICPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
ECCCCCHHCCCCEEEEECCCCCCCCCCCCCCCCEECHHHCCCCCCCCCCCEEEEEEECCE
VMRVVPFENEDVNECWIADRDRFSYEALNGPDRLTKPMLKQGGQWKEVDWQTALEYVANG
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LRGIQSEHGAQSIGALVSPHSTLEELHLATLLVRGLGSDNIDYRLRNAEFTAPEGVRWLG
HHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEECC
MPIAALSTLQSVLVVGSNLRKEHPLFAQRIRQAARKGCAVSALNSVAYDWAMPMAQSIVA
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
PAGEWAAALADIAAAVAQERGVAAPVASGRVTDAALAVARSLASGEGRAVLLGNAAAHHA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHH
QASSLLALAQWIGAQTGAVVGYLTEAANTVGAQFVRAQPRQGGLDAGRMLAGGLKAALLL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEEE
NTEPVHDSAAGARAAQALAQAEMVVTLSPFKTNLEFSDVLLPIAPFTETSGSFVNAEGRL
CCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHEEECCCCCCCCCCEECCCHHH
QSFHAVVKPLGDARPAWKVLRVLGNLLGLQGIGFETSQEVLAHAVGATGAELPTHLPADR
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
LANTTSAAPAVPAAAGTPEPVVAAIYQLDSLVRRAPSLQLTADGRQATVAVEGAAA
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCC
>Mature Secondary Structure
MVEIELDGKKVEVAEGCMVMHAAEKAGTYIPHFCYHKKLSIAANCRMCLVDVEKAPKPMP
CEEEEECCCEEEHHHCCCEEEEHHHCCCCCCHHHHHCCEEEECCCEEEEEECCCCCCCCC
ACATPVTQGMIVRTKSDKAIKAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGSS
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCC
SRYEEEKRVVFHKDVGPLISMEEMTRCIHCTRCVRFGQEVAGVMELGMIHRGEHSEITTV
CCCHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VGDTVDSELSGNMIDICPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
ECCCCCHHCCCCEEEEECCCCCCCCCCCCCCCCEECHHHCCCCCCCCCCCEEEEEEECCE
VMRVVPFENEDVNECWIADRDRFSYEALNGPDRLTKPMLKQGGQWKEVDWQTALEYVANG
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LRGIQSEHGAQSIGALVSPHSTLEELHLATLLVRGLGSDNIDYRLRNAEFTAPEGVRWLG
HHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEECC
MPIAALSTLQSVLVVGSNLRKEHPLFAQRIRQAARKGCAVSALNSVAYDWAMPMAQSIVA
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
PAGEWAAALADIAAAVAQERGVAAPVASGRVTDAALAVARSLASGEGRAVLLGNAAAHHA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHH
QASSLLALAQWIGAQTGAVVGYLTEAANTVGAQFVRAQPRQGGLDAGRMLAGGLKAALLL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEEE
NTEPVHDSAAGARAAQALAQAEMVVTLSPFKTNLEFSDVLLPIAPFTETSGSFVNAEGRL
CCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHEEECCCCCCCCCCEECCCHHH
QSFHAVVKPLGDARPAWKVLRVLGNLLGLQGIGFETSQEVLAHAVGATGAELPTHLPADR
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
LANTTSAAPAVPAAAGTPEPVVAAIYQLDSLVRRAPSLQLTADGRQATVAVEGAAA
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]