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The map label for this gene is qorA [H]

Identifier: 120609947

GI number: 120609947

Start: 1385477

End: 1386481

Strand: Direct

Name: qorA [H]

Synonym: Aave_1260

Alternate gene names: 120609947

Gene position: 1385477-1386481 (Clockwise)

Preceding gene: 120609946

Following gene: 120609948

Centisome position: 25.88

GC content: 73.03

Gene sequence:

>1005_bases
ATGGCGACCACCATGCGTGCCGTGGAAATCGCGGGCTCCGGCGGCCCGGAAGTGCTGCGTCTCGCCGAGCGGCCGGTGCC
GCGGCCGGGCGTCGGCGAGCTGCTGATCCGCGTCGCGGCCAGCGGCATCAACCGGCCCGACGTGCTGCAGCGCAAGGGGC
ACTATGCGCCCCCGCCGGGCGCCTCCGACCTGCCCGGGCTCGAAGTGGCCGGCACCATCGCGGAAGGCGACGGGTCGGCG
ATGGCCGCGGCCGGCCTGAAGGTGGGCGACCGCGTGTGCGCGCTGGTCGCGGGCGGCGGCTATGCCGAATGGTGCGTCGC
GCCCGTCGCGCAGTGCCTGCCGGTGCCCGAGGGCTGGAGCGACGTGGAGGCAGCCTCCCTGCCCGAGACCTTCTTCACGG
TGTGGAGCAACGTGTTCGACCGCGGCCGCCTCGCGGCCGGCGAAACCCTGCTGGTGCAGGGCGGCAGCAGCGGCATCGGC
GTCACGGCCATCCAGCTCGGCCGCGCCTTCGGCGCCACCGTGATCGTGACGGCGGGGTCGGACGAGAAGTGCCGTACCTG
CCTGGAGCTCGGCGCGCACCATGCCATCAACTACAAGACCCAGGACTTCGTGGCCGAGGCCCGGCGCATCACCGATGGCC
GTGGCGTGGACGTGGTCCTCGACATGGTGGCGGGTGACTATGTGGCGCGCGAGGTCGAGTGCCTGGCCGAGGATGGCCGC
CTGGTCATCATCGCCGTGCAGGGCGGGGTGCAGTCCTCCTTCGATGCGGGGCTGGTGCTGCGCCGCCGCCTCACGGTGAC
GGGCTCGACGCTGCGCCCACGCTCCGTCGCGTTCAAGGGCGCCATCGCGGCCGCCCTGCGCGAGCGGGTGTGGCCGCTGC
TGGTGGCACGCACCGTGCGGCCCGTGGTGCACAGCACCTTCCCGGCGGCCGAGGCGTCCCGCGCCCATGCGCTCATGGAG
TCGAGCCAGCATGCCGGCAAGATCGTTTTGACGTGGACAGCATGA

Upstream 100 bases:

>100_bases
GATGCCTGAGCTTCGGCCCCGCCTCCGGCGGCGGTGACCTCCGGACCGGCCCTGGCCGGTCCGGCCTCCTTTTGAAACCT
GACATCCCTGGGGATCCAGT

Downstream 100 bases:

>100_bases
CAAAGAAGAAACTCATCGCGGGCAACTGGAAGATGAATGGCACCCTGGGTGCCAATGCCGCGCTGCTGCAGGCGCTGCGC
GGCGGCCTCGAGGCGGGCGC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MATTMRAVEIAGSGGPEVLRLAERPVPRPGVGELLIRVAASGINRPDVLQRKGHYAPPPGASDLPGLEVAGTIAEGDGSA
MAAAGLKVGDRVCALVAGGGYAEWCVAPVAQCLPVPEGWSDVEAASLPETFFTVWSNVFDRGRLAAGETLLVQGGSSGIG
VTAIQLGRAFGATVIVTAGSDEKCRTCLELGAHHAINYKTQDFVAEARRITDGRGVDVVLDMVAGDYVAREVECLAEDGR
LVIIAVQGGVQSSFDAGLVLRRRLTVTGSTLRPRSVAFKGAIAAALRERVWPLLVARTVRPVVHSTFPAAEASRAHALME
SSQHAGKIVLTWTA

Sequences:

>Translated_334_residues
MATTMRAVEIAGSGGPEVLRLAERPVPRPGVGELLIRVAASGINRPDVLQRKGHYAPPPGASDLPGLEVAGTIAEGDGSA
MAAAGLKVGDRVCALVAGGGYAEWCVAPVAQCLPVPEGWSDVEAASLPETFFTVWSNVFDRGRLAAGETLLVQGGSSGIG
VTAIQLGRAFGATVIVTAGSDEKCRTCLELGAHHAINYKTQDFVAEARRITDGRGVDVVLDMVAGDYVAREVECLAEDGR
LVIIAVQGGVQSSFDAGLVLRRRLTVTGSTLRPRSVAFKGAIAAALRERVWPLLVARTVRPVVHSTFPAAEASRAHALME
SSQHAGKIVLTWTA
>Mature_333_residues
ATTMRAVEIAGSGGPEVLRLAERPVPRPGVGELLIRVAASGINRPDVLQRKGHYAPPPGASDLPGLEVAGTIAEGDGSAM
AAAGLKVGDRVCALVAGGGYAEWCVAPVAQCLPVPEGWSDVEAASLPETFFTVWSNVFDRGRLAAGETLLVQGGSSGIGV
TAIQLGRAFGATVIVTAGSDEKCRTCLELGAHHAINYKTQDFVAEARRITDGRGVDVVLDMVAGDYVAREVECLAEDGRL
VIIAVQGGVQSSFDAGLVLRRRLTVTGSTLRPRSVAFKGAIAAALRERVWPLLVARTVRPVVHSTFPAAEASRAHALMES
SQHAGKIVLTWTA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=39.1566265060241, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=39.1566265060241, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI194239674, Length=333, Percent_Identity=30.03003003003, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI13236495, Length=333, Percent_Identity=30.03003003003, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI24308257, Length=349, Percent_Identity=29.2263610315186, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI18379349, Length=343, Percent_Identity=28.2798833819242, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI194239676, Length=230, Percent_Identity=33.9130434782609, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI41872631, Length=327, Percent_Identity=30.2752293577982, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI28557745, Length=323, Percent_Identity=31.8885448916409, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI197927207, Length=189, Percent_Identity=26.4550264550265, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI47519420, Length=360, Percent_Identity=25.5555555555556, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1790485, Length=330, Percent_Identity=30, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787863, Length=350, Percent_Identity=26, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI226510941, Length=286, Percent_Identity=25.5244755244755, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=332, Percent_Identity=26.2048192771084, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=316, Percent_Identity=28.1645569620253, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=336, Percent_Identity=26.7857142857143, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323961, Length=356, Percent_Identity=23.5955056179775, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI19920632, Length=306, Percent_Identity=29.4117647058824, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221330659, Length=309, Percent_Identity=28.4789644012945, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24581345, Length=257, Percent_Identity=28.4046692607004, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34833; Mature: 34702

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTMRAVEIAGSGGPEVLRLAERPVPRPGVGELLIRVAASGINRPDVLQRKGHYAPPPG
CCCCEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCC
ASDLPGLEVAGTIAEGDGSAMAAAGLKVGDRVCALVAGGGYAEWCVAPVAQCLPVPEGWS
CCCCCCCEEEEEEECCCCCEEEHHCCHHCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCC
DVEAASLPETFFTVWSNVFDRGRLAAGETLLVQGGSSGIGVTAIQLGRAFGATVIVTAGS
CCCHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCC
DEKCRTCLELGAHHAINYKTQDFVAEARRITDGRGVDVVLDMVAGDYVAREVECLAEDGR
CHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
LVIIAVQGGVQSSFDAGLVLRRRLTVTGSTLRPRSVAFKGAIAAALRERVWPLLVARTVR
EEEEEECCCCCCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PVVHSTFPAAEASRAHALMESSQHAGKIVLTWTA
HHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEEC
>Mature Secondary Structure 
ATTMRAVEIAGSGGPEVLRLAERPVPRPGVGELLIRVAASGINRPDVLQRKGHYAPPPG
CCCEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCC
ASDLPGLEVAGTIAEGDGSAMAAAGLKVGDRVCALVAGGGYAEWCVAPVAQCLPVPEGWS
CCCCCCCEEEEEEECCCCCEEEHHCCHHCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCC
DVEAASLPETFFTVWSNVFDRGRLAAGETLLVQGGSSGIGVTAIQLGRAFGATVIVTAGS
CCCHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCC
DEKCRTCLELGAHHAINYKTQDFVAEARRITDGRGVDVVLDMVAGDYVAREVECLAEDGR
CHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
LVIIAVQGGVQSSFDAGLVLRRRLTVTGSTLRPRSVAFKGAIAAALRERVWPLLVARTVR
EEEEEECCCCCCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PVVHSTFPAAEASRAHALMESSQHAGKIVLTWTA
HHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]