Click here to switch to the map view.

The map label for this gene is yfbQ [H]

Identifier: 120609924

GI number: 120609924

Start: 1361158

End: 1362396

Strand: Direct

Name: yfbQ [H]

Synonym: Aave_1237

Alternate gene names: 120609924

Gene position: 1361158-1362396 (Clockwise)

Preceding gene: 120609919

Following gene: 120609925

Centisome position: 25.43

GC content: 66.26

Gene sequence:

>1239_bases
ATGAAGACGATCCACAAGTCCGCGAAGCTGAATAACGTTCTCTACGATGTGCGGGGCCCGATCGTGGATGCGGCCAAGCA
GATGGAGGACGAGGGCCAGAAGATCATCAAGCTCAACATCGGCAACCTCGCGCCGTTCGGCTTCGATGCGCCCGAGGAGA
TCCAGCAGGACATGATCCGCAACCTGCCGAATTCGGCGGGCTATTCGGACAGCAAGGGCATCTTCGCCGCGCGCAAGGCC
GTGATGCACTACAGCCAGCAGCAGGGCGTGAAGGGCGTGACGCTCGACGACATCTACCTGGGCAATGGCGCGAGCGACCT
GATCACCATGGCCACCAATGCGCTGCTCGACGACGGCGACGAGCTGCTGGTGCCGGCGCCCGACTATCCGCTCTGGACCG
CGGCGGCCAGCCTGTCCGGCGGCCGGCCGGTGCACTACCTCTGCGACGAGGCCAACGGCTGGATGCCGAACCTCGACGAC
ATCCGCGCCAAGATCACCCCCCGCACCAAGGGCCTCGTGGTGATCAACCCGAACAATCCCACGGGCGCGCTGTATTCCGA
CGAGTTGCTGCGCGGGCTCGTGCAGATCGCGCGCGACCACGGTCTCGTGCTGCTGGCCGACGAGGTGTACGACAAGGTGC
TCTACGACGGCGAGCGCCACACCGCCATGGCGAGCCTCTCGACCGACGTGCTCACGCTCACCTTCAATTCGCTCTCGAAG
GCCTACCGCTCGTGCGGCTACCGCGCCGGCTGGATGGTGGTGTCGGGCAACAAGGCCGTGGCCCGCGACTACATCGAGGG
CATCAACATGCTCGCCAACATCAAGCTCGGCTCCAACGTGCCCGGGCAGTGGGCGATCCAGACCGCGCTGGGCGGCTACC
AGAGCATCAACGATCTGGTCCGCGAAGGCGGGCGCCTCTGCCGGCAGCGCGACCTGGCCTACGAACTCATCTCGGCGATC
CCGGGCGTGAGCTGCGTGAAGCCCAAGGCGGCTCTCTACATGTTCCCGCGCCTCGACCCGGCCATGTACCCCATCGCCGA
CGACCGCCAGTTCTTCATGGAAGTGCTGCGCGCCACCCGCGTGATGCTGGTGCAGGGGTCGGGCTTCAACTACCCGGACC
AGCAGCATTTCCGCATCGTGTTCCTCCCGCACGAGGACGACCTGCGCGAGGCCATCGGCCGGCTCGCGGGCTTCCTCGAG
CAGTACCGGCGCAAGCACGCGGCCGCTGCTGCCGAGTGA

Upstream 100 bases:

>100_bases
CAGAGGCTGCGCCGCCTGGCGGGGTATCGGGGAGCGTTCTCCGGCGCCATACCGTTCACTCTTCCTGGCCCCGCGGCGTG
CGCCCCGGGCCTTTCGCACG

Downstream 100 bases:

>100_bases
GCGGCCGGGCGCGGCATGTCCTCTCTCCATCCAACCATCGCCGGCAGCGTTCATCCCTCTCGCGCGCTGCGGCACCATCT
GACTGACTGAGATACCGATC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKTIHKSAKLNNVLYDVRGPIVDAAKQMEDEGQKIIKLNIGNLAPFGFDAPEEIQQDMIRNLPNSAGYSDSKGIFAARKA
VMHYSQQQGVKGVTLDDIYLGNGASDLITMATNALLDDGDELLVPAPDYPLWTAAASLSGGRPVHYLCDEANGWMPNLDD
IRAKITPRTKGLVVINPNNPTGALYSDELLRGLVQIARDHGLVLLADEVYDKVLYDGERHTAMASLSTDVLTLTFNSLSK
AYRSCGYRAGWMVVSGNKAVARDYIEGINMLANIKLGSNVPGQWAIQTALGGYQSINDLVREGGRLCRQRDLAYELISAI
PGVSCVKPKAALYMFPRLDPAMYPIADDRQFFMEVLRATRVMLVQGSGFNYPDQQHFRIVFLPHEDDLREAIGRLAGFLE
QYRRKHAAAAAE

Sequences:

>Translated_412_residues
MKTIHKSAKLNNVLYDVRGPIVDAAKQMEDEGQKIIKLNIGNLAPFGFDAPEEIQQDMIRNLPNSAGYSDSKGIFAARKA
VMHYSQQQGVKGVTLDDIYLGNGASDLITMATNALLDDGDELLVPAPDYPLWTAAASLSGGRPVHYLCDEANGWMPNLDD
IRAKITPRTKGLVVINPNNPTGALYSDELLRGLVQIARDHGLVLLADEVYDKVLYDGERHTAMASLSTDVLTLTFNSLSK
AYRSCGYRAGWMVVSGNKAVARDYIEGINMLANIKLGSNVPGQWAIQTALGGYQSINDLVREGGRLCRQRDLAYELISAI
PGVSCVKPKAALYMFPRLDPAMYPIADDRQFFMEVLRATRVMLVQGSGFNYPDQQHFRIVFLPHEDDLREAIGRLAGFLE
QYRRKHAAAAAE
>Mature_412_residues
MKTIHKSAKLNNVLYDVRGPIVDAAKQMEDEGQKIIKLNIGNLAPFGFDAPEEIQQDMIRNLPNSAGYSDSKGIFAARKA
VMHYSQQQGVKGVTLDDIYLGNGASDLITMATNALLDDGDELLVPAPDYPLWTAAASLSGGRPVHYLCDEANGWMPNLDD
IRAKITPRTKGLVVINPNNPTGALYSDELLRGLVQIARDHGLVLLADEVYDKVLYDGERHTAMASLSTDVLTLTFNSLSK
AYRSCGYRAGWMVVSGNKAVARDYIEGINMLANIKLGSNVPGQWAIQTALGGYQSINDLVREGGRLCRQRDLAYELISAI
PGVSCVKPKAALYMFPRLDPAMYPIADDRQFFMEVLRATRVMLVQGSGFNYPDQQHFRIVFLPHEDDLREAIGRLAGFLE
QYRRKHAAAAAE

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=472, Percent_Identity=29.4491525423729, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI215599424, Length=383, Percent_Identity=31.0704960835509, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI4507369, Length=402, Percent_Identity=26.1194029850746, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI4885351, Length=449, Percent_Identity=27.3942093541203, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI95147551, Length=207, Percent_Identity=28.0193236714976, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI169881279, Length=207, Percent_Identity=28.0193236714976, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI169881281, Length=143, Percent_Identity=30.0699300699301, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI56713254, Length=167, Percent_Identity=23.9520958083832, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI56713256, Length=167, Percent_Identity=23.9520958083832, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=59.1584158415842, Blast_Score=523, Evalue=1e-150,
Organism=Escherichia coli, GI1788722, Length=395, Percent_Identity=26.0759493670886, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786816, Length=290, Percent_Identity=23.7931034482759, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=414, Percent_Identity=28.2608695652174, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=490, Percent_Identity=26.3265306122449, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=214, Percent_Identity=30.3738317757009, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=214, Percent_Identity=30.3738317757009, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=311, Percent_Identity=28.2958199356913, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=210, Percent_Identity=27.6190476190476, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=382, Percent_Identity=30.3664921465969, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6323118, Length=391, Percent_Identity=28.3887468030691, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6322401, Length=239, Percent_Identity=26.3598326359833, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI18859735, Length=412, Percent_Identity=28.6407766990291, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI45551451, Length=464, Percent_Identity=26.5086206896552, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24641770, Length=464, Percent_Identity=26.5086206896552, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24641760, Length=464, Percent_Identity=26.5086206896552, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24641768, Length=464, Percent_Identity=26.5086206896552, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24641766, Length=464, Percent_Identity=26.5086206896552, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24641764, Length=464, Percent_Identity=26.5086206896552, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI28573069, Length=177, Percent_Identity=23.728813559322, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24646114, Length=177, Percent_Identity=23.728813559322, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573067, Length=177, Percent_Identity=23.728813559322, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573065, Length=177, Percent_Identity=23.728813559322, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45408; Mature: 45408

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIHKSAKLNNVLYDVRGPIVDAAKQMEDEGQKIIKLNIGNLAPFGFDAPEEIQQDMIR
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPNSAGYSDSKGIFAARKAVMHYSQQQGVKGVTLDDIYLGNGASDLITMATNALLDDGD
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCEEECCCHHHHHHHHHHHHHCCCC
ELLVPAPDYPLWTAAASLSGGRPVHYLCDEANGWMPNLDDIRAKITPRTKGLVVINPNNP
EEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGALYSDELLRGLVQIARDHGLVLLADEVYDKVLYDGERHTAMASLSTDVLTLTFNSLSK
CCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHCCCCEEEEEHHHHHH
AYRSCGYRAGWMVVSGNKAVARDYIEGINMLANIKLGSNVPGQWAIQTALGGYQSINDLV
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHEEEEEECCCCCCCEEHHHHHCCHHHHHHHH
REGGRLCRQRDLAYELISAIPGVSCVKPKAALYMFPRLDPAMYPIADDRQFFMEVLRATR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHHHE
VMLVQGSGFNYPDQQHFRIVFLPHEDDLREAIGRLAGFLEQYRRKHAAAAAE
EEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTIHKSAKLNNVLYDVRGPIVDAAKQMEDEGQKIIKLNIGNLAPFGFDAPEEIQQDMIR
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPNSAGYSDSKGIFAARKAVMHYSQQQGVKGVTLDDIYLGNGASDLITMATNALLDDGD
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCEEECCCHHHHHHHHHHHHHCCCC
ELLVPAPDYPLWTAAASLSGGRPVHYLCDEANGWMPNLDDIRAKITPRTKGLVVINPNNP
EEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGALYSDELLRGLVQIARDHGLVLLADEVYDKVLYDGERHTAMASLSTDVLTLTFNSLSK
CCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHCCCCEEEEEHHHHHH
AYRSCGYRAGWMVVSGNKAVARDYIEGINMLANIKLGSNVPGQWAIQTALGGYQSINDLV
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHEEEEEECCCCCCCEEHHHHHCCHHHHHHHH
REGGRLCRQRDLAYELISAIPGVSCVKPKAALYMFPRLDPAMYPIADDRQFFMEVLRATR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHHHE
VMLVQGSGFNYPDQQHFRIVFLPHEDDLREAIGRLAGFLEQYRRKHAAAAAE
EEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]