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The map label for this gene is pucI [H]

Identifier: 120609790

GI number: 120609790

Start: 1203346

End: 1204890

Strand: Reverse

Name: pucI [H]

Synonym: Aave_1098

Alternate gene names: 120609790

Gene position: 1204890-1203346 (Counterclockwise)

Preceding gene: 120609791

Following gene: 120609789

Centisome position: 22.51

GC content: 66.93

Gene sequence:

>1545_bases
ATGCAATCCGCCACCAGCCCGGCGGGCACCGCAGGCCACGCCGCGATCGCCCAGCCCGCCACGTCCACGTCCACGTCCAC
GTCCACGCCTGCGCCCGCCGCCCCGGCCTCGCCCCACGCCGGCAATGCGCTCATCAAGCCCGGCTACGACCCGCGCCTCA
CCAACGAGGACCTCGCCCCGCTCAGGAAACAGACCTGGGGCCAGTACAACATCTTCGCGTTCTGGATGTCCGACGTGCAC
AGCGTGGGCGGCTATGTCACCGCCGGCAGCCTGTTCGCGCTGGGGCTGTCCAGCTGGCACGTGCTGGCCGCGCTGCTGAT
CGGCATCGTCATCGTGCAGATCTTCTGCAACCTGGTGGCCAAGCCCAGCCAGGTGACGGGCGTGCCCTACCCCGTGATCT
GCCGCGCCTCGTTCGGCGTGCTGGGCGCCAACATCCCGGCCATCATCCGCGGGCTGATCGCGGTGGCCTGGTACGGCATC
CAGACCTACCTGGCCTCCAGCGCCTTCATGATCCTGGCGCTGCATTTCTACCCCTCGCTCGACGCCTATGCCGATGTCAC
GCGGCACGGCTTCGCGGGCCTGTCCACGCTGGGCTGGGTGTCGTTCATGGTCATGTGGGTGCTGCAGGCGCTGGTGTTCT
GGCACGGCATGGAGGCCATCCGCCGCTTCATCGACTGGGCCGGCCCGGGCGTCTATGTGGTGATGGCCATCCTCTGCGGC
TGGCTGGTCTGGAAGGCCGGCTGGAAGAACATCAACCTGAACCTGGGCGGCGTGCGCTTCCAGGGCTGGGACGCGGTGCC
GGTGATGCTCTCGGCCATCGCGCTGGTGGTGAGCTACTTCAGCGGCCCGATGCTCAACTTCGGCGACTTCTCCCGCTACG
GTAAGAGCTTCGACGCGGTGAAGAAGGGCAATTTCTGGGGCCTGCCGGTCAACTTCGTGTTCTTCTCGCTGCTCACCGTG
GTCACCACCGCCGCCACGCTGCCCGTGTTCGGCGAACTCATCACCGACCCGGTCCACACCGTGGGCCGCATCGACTCCAC
CACCGCCGTGGTGCTGGGCGCGCTCACCTTCATGATCGCCACCGTGGGCATCAACATCGTGGCCAACTTCGTGTCGCCGG
CGTTCGACTTCTCCAACGTGGCGCCGCAGCATATCAGCTGGCGCACGGGCGGCATGATCGCCGCCGTGGGCTCGATCTTC
ATCACGCCCTGGAACCTCTACAACAACCCGCAGGTCATCCACTACACGCTGGACATCCTGGGCTCGTTCATCGGCCCGCT
GTTCGGCATCCTGATCGCCGACTACTACTTCGTGCGCCGCCAGCAGGTGGCGGTCGATGACCTCTACACCATGCAGCCCG
AGGGCCGCTACTGGTACCGGGGCGGCTACAACCCCCGCGCCGTGATGACCATGGTGCCCGCCGCGCTGGTGCCCATCCTG
TGCGTGGTCGTGCCGAGCTGGCGCGGCGCCGCCAACTATGCCTGGTTCATCGGCATGGGCCTGGGGCTGGTCATCTACCT
CGCACTGAACCGCAAGCAGAACTGA

Upstream 100 bases:

>100_bases
AAGCACCGAGCCGCACGGGCGCTCCTGGCCTTTGAATGCATCCATTTTTTGTATACAAATTCGCATGCATTCTGGGAAGC
CAACACAAGGAGACAGCCCC

Downstream 100 bases:

>100_bases
AACCGAAGAAGGAACGGGCAACGCCCATGCGTATCAAGATCATCAATCCCAACACCACCTGGAGCATGACCGAGAAGATC
GGGGCCTGCGCGCGCGCCGT

Product: cytosine/purines, uracil, thiamine, allantoin permease

Products: NA

Alternate protein names: Allantoin transport protein [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQSATSPAGTAGHAAIAQPATSTSTSTSTPAPAAPASPHAGNALIKPGYDPRLTNEDLAPLRKQTWGQYNIFAFWMSDVH
SVGGYVTAGSLFALGLSSWHVLAALLIGIVIVQIFCNLVAKPSQVTGVPYPVICRASFGVLGANIPAIIRGLIAVAWYGI
QTYLASSAFMILALHFYPSLDAYADVTRHGFAGLSTLGWVSFMVMWVLQALVFWHGMEAIRRFIDWAGPGVYVVMAILCG
WLVWKAGWKNINLNLGGVRFQGWDAVPVMLSAIALVVSYFSGPMLNFGDFSRYGKSFDAVKKGNFWGLPVNFVFFSLLTV
VTTAATLPVFGELITDPVHTVGRIDSTTAVVLGALTFMIATVGINIVANFVSPAFDFSNVAPQHISWRTGGMIAAVGSIF
ITPWNLYNNPQVIHYTLDILGSFIGPLFGILIADYYFVRRQQVAVDDLYTMQPEGRYWYRGGYNPRAVMTMVPAALVPIL
CVVVPSWRGAANYAWFIGMGLGLVIYLALNRKQN

Sequences:

>Translated_514_residues
MQSATSPAGTAGHAAIAQPATSTSTSTSTPAPAAPASPHAGNALIKPGYDPRLTNEDLAPLRKQTWGQYNIFAFWMSDVH
SVGGYVTAGSLFALGLSSWHVLAALLIGIVIVQIFCNLVAKPSQVTGVPYPVICRASFGVLGANIPAIIRGLIAVAWYGI
QTYLASSAFMILALHFYPSLDAYADVTRHGFAGLSTLGWVSFMVMWVLQALVFWHGMEAIRRFIDWAGPGVYVVMAILCG
WLVWKAGWKNINLNLGGVRFQGWDAVPVMLSAIALVVSYFSGPMLNFGDFSRYGKSFDAVKKGNFWGLPVNFVFFSLLTV
VTTAATLPVFGELITDPVHTVGRIDSTTAVVLGALTFMIATVGINIVANFVSPAFDFSNVAPQHISWRTGGMIAAVGSIF
ITPWNLYNNPQVIHYTLDILGSFIGPLFGILIADYYFVRRQQVAVDDLYTMQPEGRYWYRGGYNPRAVMTMVPAALVPIL
CVVVPSWRGAANYAWFIGMGLGLVIYLALNRKQN
>Mature_514_residues
MQSATSPAGTAGHAAIAQPATSTSTSTSTPAPAAPASPHAGNALIKPGYDPRLTNEDLAPLRKQTWGQYNIFAFWMSDVH
SVGGYVTAGSLFALGLSSWHVLAALLIGIVIVQIFCNLVAKPSQVTGVPYPVICRASFGVLGANIPAIIRGLIAVAWYGI
QTYLASSAFMILALHFYPSLDAYADVTRHGFAGLSTLGWVSFMVMWVLQALVFWHGMEAIRRFIDWAGPGVYVVMAILCG
WLVWKAGWKNINLNLGGVRFQGWDAVPVMLSAIALVVSYFSGPMLNFGDFSRYGKSFDAVKKGNFWGLPVNFVFFSLLTV
VTTAATLPVFGELITDPVHTVGRIDSTTAVVLGALTFMIATVGINIVANFVSPAFDFSNVAPQHISWRTGGMIAAVGSIF
ITPWNLYNNPQVIHYTLDILGSFIGPLFGILIADYYFVRRQQVAVDDLYTMQPEGRYWYRGGYNPRAVMTMVPAALVPIL
CVVVPSWRGAANYAWFIGMGLGLVIYLALNRKQN

Specific function: Transport of allantoin [H]

COG id: COG1953

COG function: function code FH; Cytosine/uracil/thiamine/allantoin permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI87081749, Length=468, Percent_Identity=27.991452991453, Blast_Score=187, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6319495, Length=464, Percent_Identity=25.2155172413793, Blast_Score=137, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6322219, Length=441, Percent_Identity=25.1700680272109, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6319429, Length=441, Percent_Identity=26.530612244898, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324766, Length=438, Percent_Identity=22.8310502283105, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323266, Length=442, Percent_Identity=22.1719457013575, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324645, Length=438, Percent_Identity=22.3744292237443, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 55717; Mature: 55717

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSATSPAGTAGHAAIAQPATSTSTSTSTPAPAAPASPHAGNALIKPGYDPRLTNEDLAP
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LRKQTWGQYNIFAFWMSDVHSVGGYVTAGSLFALGLSSWHVLAALLIGIVIVQIFCNLVA
HHHHCCCCEEEEEEEHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPSQVTGVPYPVICRASFGVLGANIPAIIRGLIAVAWYGIQTYLASSAFMILALHFYPSL
CCCCCCCCCCCEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DAYADVTRHGFAGLSTLGWVSFMVMWVLQALVFWHGMEAIRRFIDWAGPGVYVVMAILCG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
WLVWKAGWKNINLNLGGVRFQGWDAVPVMLSAIALVVSYFSGPMLNFGDFSRYGKSFDAV
HHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHH
KKGNFWGLPVNFVFFSLLTVVTTAATLPVFGELITDPVHTVGRIDSTTAVVLGALTFMIA
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TVGINIVANFVSPAFDFSNVAPQHISWRTGGMIAAVGSIFITPWNLYNNPQVIHYTLDIL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCCEEEEHHHHHH
GSFIGPLFGILIADYYFVRRQQVAVDDLYTMQPEGRYWYRGGYNPRAVMTMVPAALVPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCHHHHHHHHHHHHHHH
CVVVPSWRGAANYAWFIGMGLGLVIYLALNRKQN
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQSATSPAGTAGHAAIAQPATSTSTSTSTPAPAAPASPHAGNALIKPGYDPRLTNEDLAP
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LRKQTWGQYNIFAFWMSDVHSVGGYVTAGSLFALGLSSWHVLAALLIGIVIVQIFCNLVA
HHHHCCCCEEEEEEEHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPSQVTGVPYPVICRASFGVLGANIPAIIRGLIAVAWYGIQTYLASSAFMILALHFYPSL
CCCCCCCCCCCEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DAYADVTRHGFAGLSTLGWVSFMVMWVLQALVFWHGMEAIRRFIDWAGPGVYVVMAILCG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
WLVWKAGWKNINLNLGGVRFQGWDAVPVMLSAIALVVSYFSGPMLNFGDFSRYGKSFDAV
HHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHH
KKGNFWGLPVNFVFFSLLTVVTTAATLPVFGELITDPVHTVGRIDSTTAVVLGALTFMIA
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TVGINIVANFVSPAFDFSNVAPQHISWRTGGMIAAVGSIFITPWNLYNNPQVIHYTLDIL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCCEEEEHHHHHH
GSFIGPLFGILIADYYFVRRQQVAVDDLYTMQPEGRYWYRGGYNPRAVMTMVPAALVPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCHHHHHHHHHHHHHHH
CVVVPSWRGAANYAWFIGMGLGLVIYLALNRKQN
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 11344136 [H]