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The map label for this gene is pyrR [H]

Identifier: 120609603

GI number: 120609603

Start: 990936

End: 991460

Strand: Direct

Name: pyrR [H]

Synonym: Aave_0909

Alternate gene names: 120609603

Gene position: 990936-991460 (Clockwise)

Preceding gene: 120609602

Following gene: 120609604

Centisome position: 18.51

GC content: 74.29

Gene sequence:

>525_bases
ATGACTCCGACGCCAACTTCCGCCCCGCCCGGGGCCCTCGCCCTCGATGCCGAGGCGCTCTACCGCGAACTGCTGTCCGG
CGTGCGCGCTCTGCGCACCCCGCAGACGCATCTGGCCGGCATCGCGTCCGGAGGAGCCTGGCTGGCCGAGCGCCTGCAGC
AGGACCTGGGCCTGCCGGGCGAAGCCGGCGTGCTGTCCTCGGCGCTGCACCGCGACGACTTCTCCCAGCGCGGCCTGGCC
GCCAGCGCCCAGACCCGCCTGGGCTTCGAGGTGAATGGCGCCGACATCCTGCTGCTGGACGACGTGCTCTACACGGGCCG
CACCATCCGCGCGGTGCTCAACGAACTCTTCGACTACGGGCGCCCGGCGCGCGTGCGGCTCGCCGTGCTGGTGGACCGCG
GCGGCCGGGAGCTGCCCGTGCAGGCCGAGTTCGCCGCGGCGCGCGTGGCGCTTCCCGCCACGCAGTCACTGGCGCTGGCC
CGTGCGGACGGCGGCGCTTTCCACTTCCACGTCCAGGAGGCCTGA

Upstream 100 bases:

>100_bases
ACGAGCGCTACAGCACCACCGAAGCCCATGCGGGCGGTGCGAAAGATGCCGATGCCGCATCCGCCTGCATCATCCTGGAG
CAGTTCTTGAGGCAACTTCC

Downstream 100 bases:

>100_bases
CGCCGTGCTCTCCAAGCGCAACCCCCAGCTCAATCGCAATGGCGAGTTGATCCACCTGCTGTCCATCGAAGGCCTGCCGC
GCAGCATCGTCACGCACATC

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTPTPTSAPPGALALDAEALYRELLSGVRALRTPQTHLAGIASGGAWLAERLQQDLGLPGEAGVLSSALHRDDFSQRGLA
ASAQTRLGFEVNGADILLLDDVLYTGRTIRAVLNELFDYGRPARVRLAVLVDRGGRELPVQAEFAAARVALPATQSLALA
RADGGAFHFHVQEA

Sequences:

>Translated_174_residues
MTPTPTSAPPGALALDAEALYRELLSGVRALRTPQTHLAGIASGGAWLAERLQQDLGLPGEAGVLSSALHRDDFSQRGLA
ASAQTRLGFEVNGADILLLDDVLYTGRTIRAVLNELFDYGRPARVRLAVLVDRGGRELPVQAEFAAARVALPATQSLALA
RADGGAFHFHVQEA
>Mature_173_residues
TPTPTSAPPGALALDAEALYRELLSGVRALRTPQTHLAGIASGGAWLAERLQQDLGLPGEAGVLSSALHRDDFSQRGLAA
SAQTRLGFEVNGADILLLDDVLYTGRTIRAVLNELFDYGRPARVRLAVLVDRGGRELPVQAEFAAARVALPATQSLALAR
ADGGAFHFHVQEA

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 18390; Mature: 18259

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTPTSAPPGALALDAEALYRELLSGVRALRTPQTHLAGIASGGAWLAERLQQDLGLPG
CCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCCC
EAGVLSSALHRDDFSQRGLAASAQTRLGFEVNGADILLLDDVLYTGRTIRAVLNELFDYG
CCHHHHHHHHHCCHHHCCCCCCCHHHCCEEECCCEEEEECCHHHCCHHHHHHHHHHHHCC
RPARVRLAVLVDRGGRELPVQAEFAAARVALPATQSLALARADGGAFHFHVQEA
CCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHEEEEECCCCEEEEEEECC
>Mature Secondary Structure 
TPTPTSAPPGALALDAEALYRELLSGVRALRTPQTHLAGIASGGAWLAERLQQDLGLPG
CCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCCC
EAGVLSSALHRDDFSQRGLAASAQTRLGFEVNGADILLLDDVLYTGRTIRAVLNELFDYG
CCHHHHHHHHHCCHHHCCCCCCCHHHCCEEECCCEEEEECCHHHCCHHHHHHHHHHHHCC
RPARVRLAVLVDRGGRELPVQAEFAAARVALPATQSLALARADGGAFHFHVQEA
CCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]