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The map label for this gene is mhpR [H]

Identifier: 120609533

GI number: 120609533

Start: 909231

End: 910145

Strand: Direct

Name: mhpR [H]

Synonym: Aave_0839

Alternate gene names: 120609533

Gene position: 909231-910145 (Clockwise)

Preceding gene: 120609532

Following gene: 120609538

Centisome position: 16.99

GC content: 68.85

Gene sequence:

>915_bases
ATGCCCCCCGCATTCGCTGGCCTTCCATTTCCACAGAGAGAACCACCCATGAGTACCGAAGTCCGCTCCGTGCAACGTGC
GCTGCTGATCCTGCGCGTCATGAACGAGCGCTCCACCTGGAGCCTGCAGGAACTGCACCAGCGCACGGGCCTCGCCAAAT
CCACGCTGCACCGCCTGCTGGGCACGCTGGAGCACGAGAAATACGTGCGCAGCGACCCCCATGCCTACGGGCAGTACCAG
TTGACGCTGGCCGTGAGCAACCTCAGCAGCGGCGTGAACGAGAAGCTGCGCCTGGCCGAACTCGCCGCGCCGCTCATGAT
CACGGCCACGCGGCAGATCAAGTGGCCGCTGTCGCTCGCCGTGATCGACGGGCACCAGATGCGCGTGGTCTTCTGCACCA
TGCCCTACAGCCCCTATGCCATCCGCCCCTCCAGCCTGGGCCGGCGCTACGACCTGATCCCCTCGGCGCTGGGCCGCGCC
TACCTCGCCTACTGCACCCGCGCCGAGCGCCGCATCCTCGTGGAGGCCGCCAACACGCATGGCGAGCCGCACCAGAAGAT
CACCGACATGTGGGCGCTGCGCCGGATCGTGCAGGAAACGCGCCGCCAGGGCTATGCCATCCGCTATGCGCGCAACAACT
CCGAGAGCACGGCGTTCGCGGTGCCGGTGTTCGGCGGTGGCGTGCTGCGCGGCGCGCTGGTGTATTCCACCTTCGCGAGC
CAGATGGACGACCGCATGCTCAAGCGCTTCCTCTCGCTCGTGCAGTCCACCGCTTCGCGGATCGGCGAAGAGGCCGCGCA
GTCGTCGCAGCTGCCCGGCATGCCGCTGCCGCCGCAGACGGCCGGCATCCTGGCCGCGCCGCAGCCGGCGGCGTATGCCG
GCGCCGTGTCGAACGCGCTCTCCGTGGCGGCCTGA

Upstream 100 bases:

>100_bases
GAGGCGGCCTGAAGGCATCGGGAAACCTGCCCATGGACCACCTTATTTCCGTTTCTCCAGCGCGCGTGACCGGGGGCCCG
CGCGCAATTGCGTTCCCTGA

Downstream 100 bases:

>100_bases
AGGCCCTAAGGCAGTTCCGCGCTGGCCATCCTTCCCAGGATCACGCGCGTGCGGCCCGAAAGGTACGCCGAGCCCGGGTT
CTTCTCGAAGCGCCTGGGCG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MPPAFAGLPFPQREPPMSTEVRSVQRALLILRVMNERSTWSLQELHQRTGLAKSTLHRLLGTLEHEKYVRSDPHAYGQYQ
LTLAVSNLSSGVNEKLRLAELAAPLMITATRQIKWPLSLAVIDGHQMRVVFCTMPYSPYAIRPSSLGRRYDLIPSALGRA
YLAYCTRAERRILVEAANTHGEPHQKITDMWALRRIVQETRRQGYAIRYARNNSESTAFAVPVFGGGVLRGALVYSTFAS
QMDDRMLKRFLSLVQSTASRIGEEAAQSSQLPGMPLPPQTAGILAAPQPAAYAGAVSNALSVAA

Sequences:

>Translated_304_residues
MPPAFAGLPFPQREPPMSTEVRSVQRALLILRVMNERSTWSLQELHQRTGLAKSTLHRLLGTLEHEKYVRSDPHAYGQYQ
LTLAVSNLSSGVNEKLRLAELAAPLMITATRQIKWPLSLAVIDGHQMRVVFCTMPYSPYAIRPSSLGRRYDLIPSALGRA
YLAYCTRAERRILVEAANTHGEPHQKITDMWALRRIVQETRRQGYAIRYARNNSESTAFAVPVFGGGVLRGALVYSTFAS
QMDDRMLKRFLSLVQSTASRIGEEAAQSSQLPGMPLPPQTAGILAAPQPAAYAGAVSNALSVAA
>Mature_303_residues
PPAFAGLPFPQREPPMSTEVRSVQRALLILRVMNERSTWSLQELHQRTGLAKSTLHRLLGTLEHEKYVRSDPHAYGQYQL
TLAVSNLSSGVNEKLRLAELAAPLMITATRQIKWPLSLAVIDGHQMRVVFCTMPYSPYAIRPSSLGRRYDLIPSALGRAY
LAYCTRAERRILVEAANTHGEPHQKITDMWALRRIVQETRRQGYAIRYARNNSESTAFAVPVFGGGVLRGALVYSTFASQ
MDDRMLKRFLSLVQSTASRIGEEAAQSSQLPGMPLPPQTAGILAAPQPAAYAGAVSNALSVAA

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=228, Percent_Identity=30.7017543859649, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786468, Length=232, Percent_Identity=29.3103448275862, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788131, Length=243, Percent_Identity=27.1604938271605, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 33556; Mature: 33425

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAFAGLPFPQREPPMSTEVRSVQRALLILRVMNERSTWSLQELHQRTGLAKSTLHRLL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHH
GTLEHEKYVRSDPHAYGQYQLTLAVSNLSSGVNEKLRLAELAAPLMITATRQIKWPLSLA
HHHHHHHHHHCCCCCCCEEEEEEEEEHHHCCHHHHHHHHHHHCCHHEEECCEEECCEEEE
VIDGHQMRVVFCTMPYSPYAIRPSSLGRRYDLIPSALGRAYLAYCTRAERRILVEAANTH
EECCCEEEEEEEECCCCCCEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
GEPHQKITDMWALRRIVQETRRQGYAIRYARNNSESTAFAVPVFGGGVLRGALVYSTFAS
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHH
QMDDRMLKRFLSLVQSTASRIGEEAAQSSQLPGMPLPPQTAGILAAPQPAAYAGAVSNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
SVAA
HHCC
>Mature Secondary Structure 
PPAFAGLPFPQREPPMSTEVRSVQRALLILRVMNERSTWSLQELHQRTGLAKSTLHRLL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHH
GTLEHEKYVRSDPHAYGQYQLTLAVSNLSSGVNEKLRLAELAAPLMITATRQIKWPLSLA
HHHHHHHHHHCCCCCCCEEEEEEEEEHHHCCHHHHHHHHHHHCCHHEEECCEEECCEEEE
VIDGHQMRVVFCTMPYSPYAIRPSSLGRRYDLIPSALGRAYLAYCTRAERRILVEAANTH
EECCCEEEEEEEECCCCCCEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
GEPHQKITDMWALRRIVQETRRQGYAIRYARNNSESTAFAVPVFGGGVLRGALVYSTFAS
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHH
QMDDRMLKRFLSLVQSTASRIGEEAAQSSQLPGMPLPPQTAGILAAPQPAAYAGAVSNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
SVAA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]