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The map label for this gene is radA [H]

Identifier: 120608965

GI number: 120608965

Start: 291860

End: 293239

Strand: Direct

Name: radA [H]

Synonym: Aave_0262

Alternate gene names: 120608965

Gene position: 291860-293239 (Clockwise)

Preceding gene: 120608961

Following gene: 120608966

Centisome position: 5.45

GC content: 70.58

Gene sequence:

>1380_bases
ATGGCCAAAGACAAGACCGTTTTCACCTGTACCGAATGCGGCGGCACCAGCCCGCGCTGGCTTGGCAAGTGCCCTGCCTG
CGGGGCCTGGAACACGCTGGTGGAATCGGTGGCGGAAGCCGGGCCGGGCAAGAACCGCTACAGCACGCCGCAGCATGCGG
GCCTGGCGCAGTCGCAGGCCGTGACGCCGCTGTCGGCCATCGAGGCCGCCGACGTGGCGCGCACCGCCAGCGGCATCGAG
GAACTCGACCGGGTGCTGGGCGGCGGGGTGGTCGAGGGCGGCGTGGTCCTCATCGGTGGCGATCCGGGCATCGGCAAGTC
CACCCTGCTGCTGCAGGCGCTGGATGCGCTGCAGCGCCTGGGCCTGCCCACGCTCTACGTGACGGGCGAGGAGAGCGGGG
CGCAGGTGGCGCTGCGCTCGCGCCGGCTGGGGCTGGACCACAGCCAGGTCAACGTCCTGGCGGAAATCCAGCTCGAGAAG
ATCCTCGCCACCGTCGAGGCGACGCAGCCCGCCGTGGCCGTGATCGATTCCATCCAGACCGTGTATTCGGACCAGCTCAC
CAGCGCGCCGGGCTCGGTGGCCCAGGTGCGCGAATGCGCGGCGCACCTCACGCGGGCGGCCAAGGCCACCGGCGTGTCCA
TCATCCTCGTGGGCCACGTGACCAAGGAAGGGGCGCTGGCCGGCCCGCGCGTGCTGGAGCACATGGTGGACACGGTGCTG
TACTTCGAGGGCGATACGCACAGTCAGTTCCGGCTGGTGCGCGCCATCAAGAACCGCTTCGGCGCCGTGAACGAGATCGG
CGTGTTCGCCATGACCGAGAAGGGCCTCAAGGGCGTGACCAATCCCAGCGCCATCTTCTTGAGCCAGCACAGCGAGCCGG
TGCCCGGCAGCTGCGTGCTGGTCACGCTGGAAGGCACGCGCCCCATGCTGGTGGAGATCCAGGCCCTGGTGGACGAGGGC
GGGCCCAGCCCCCGGCGCCTGTCCGTGGGCCTGGAGCGCGACCGCCTCGCCATGCTGCTGGCCGTGCTGCACCGCCACGC
GGGCGTCGCCTGCATGGACCAGGACGTGTTCGTGAACGCCGTGGGCGGCGTGCGCATCAGCGAACCCGCGGCCGACCTGG
CGGTGATGCTGGCCATCACCAGCAGCCTGCGCGGCAAGCCCCTGCCCAAGGGCTTCATCGCTTTCGGCGAAGTCGGGCTG
GCGGGCGAGGTGCGCCCTGCGCCGCGCGGCCAGGAGCGCCTGAAGGAGGCCGCCAAGCTCGGTTTCACGATGGCCGTGGT
GCCCAAGGCCAACGCGCCCAGGAAGCCCATCGAGGGCCTGACGATCCATGCGGTGGAACGGGTGGAAGAGGCCATGGAAG
TGGTCCGCGGCATGGGGTGA

Upstream 100 bases:

>100_bases
CCGGCGCCGGGCGGTCGGTCCCTCGTGCATCGCGGTACGGTGCGTCCCTCTTTCTCTTTCTCCGCCTTCCCCTTCCCCTT
CCCCCGGATACGCTTTCCCC

Downstream 100 bases:

>100_bases
ATTTCTCCCCCCCTGAGTCGCCTTCGGCGCCTTCCCCCCCCGGGGGGACGCCGCCAGTGGCCGGGCGAAGCCCGTTCCAC
GGCGTCCGCTGGCATGGCCT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MAKDKTVFTCTECGGTSPRWLGKCPACGAWNTLVESVAEAGPGKNRYSTPQHAGLAQSQAVTPLSAIEAADVARTASGIE
ELDRVLGGGVVEGGVVLIGGDPGIGKSTLLLQALDALQRLGLPTLYVTGEESGAQVALRSRRLGLDHSQVNVLAEIQLEK
ILATVEATQPAVAVIDSIQTVYSDQLTSAPGSVAQVRECAAHLTRAAKATGVSIILVGHVTKEGALAGPRVLEHMVDTVL
YFEGDTHSQFRLVRAIKNRFGAVNEIGVFAMTEKGLKGVTNPSAIFLSQHSEPVPGSCVLVTLEGTRPMLVEIQALVDEG
GPSPRRLSVGLERDRLAMLLAVLHRHAGVACMDQDVFVNAVGGVRISEPAADLAVMLAITSSLRGKPLPKGFIAFGEVGL
AGEVRPAPRGQERLKEAAKLGFTMAVVPKANAPRKPIEGLTIHAVERVEEAMEVVRGMG

Sequences:

>Translated_459_residues
MAKDKTVFTCTECGGTSPRWLGKCPACGAWNTLVESVAEAGPGKNRYSTPQHAGLAQSQAVTPLSAIEAADVARTASGIE
ELDRVLGGGVVEGGVVLIGGDPGIGKSTLLLQALDALQRLGLPTLYVTGEESGAQVALRSRRLGLDHSQVNVLAEIQLEK
ILATVEATQPAVAVIDSIQTVYSDQLTSAPGSVAQVRECAAHLTRAAKATGVSIILVGHVTKEGALAGPRVLEHMVDTVL
YFEGDTHSQFRLVRAIKNRFGAVNEIGVFAMTEKGLKGVTNPSAIFLSQHSEPVPGSCVLVTLEGTRPMLVEIQALVDEG
GPSPRRLSVGLERDRLAMLLAVLHRHAGVACMDQDVFVNAVGGVRISEPAADLAVMLAITSSLRGKPLPKGFIAFGEVGL
AGEVRPAPRGQERLKEAAKLGFTMAVVPKANAPRKPIEGLTIHAVERVEEAMEVVRGMG
>Mature_458_residues
AKDKTVFTCTECGGTSPRWLGKCPACGAWNTLVESVAEAGPGKNRYSTPQHAGLAQSQAVTPLSAIEAADVARTASGIEE
LDRVLGGGVVEGGVVLIGGDPGIGKSTLLLQALDALQRLGLPTLYVTGEESGAQVALRSRRLGLDHSQVNVLAEIQLEKI
LATVEATQPAVAVIDSIQTVYSDQLTSAPGSVAQVRECAAHLTRAAKATGVSIILVGHVTKEGALAGPRVLEHMVDTVLY
FEGDTHSQFRLVRAIKNRFGAVNEIGVFAMTEKGLKGVTNPSAIFLSQHSEPVPGSCVLVTLEGTRPMLVEIQALVDEGG
PSPRRLSVGLERDRLAMLLAVLHRHAGVACMDQDVFVNAVGGVRISEPAADLAVMLAITSSLRGKPLPKGFIAFGEVGLA
GEVRPAPRGQERLKEAAKLGFTMAVVPKANAPRKPIEGLTIHAVERVEEAMEVVRGMG

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=457, Percent_Identity=56.4551422319475, Blast_Score=501, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 48131; Mature: 48000

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDKTVFTCTECGGTSPRWLGKCPACGAWNTLVESVAEAGPGKNRYSTPQHAGLAQSQA
CCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHC
VTPLSAIEAADVARTASGIEELDRVLGGGVVEGGVVLIGGDPGIGKSTLLLQALDALQRL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHC
GLPTLYVTGEESGAQVALRSRRLGLDHSQVNVLAEIQLEKILATVEATQPAVAVIDSIQT
CCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VYSDQLTSAPGSVAQVRECAAHLTRAAKATGVSIILVGHVTKEGALAGPRVLEHMVDTVL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHHHHHHHEE
YFEGDTHSQFRLVRAIKNRFGAVNEIGVFAMTEKGLKGVTNPSAIFLSQHSEPVPGSCVL
EECCCCHHHHHHHHHHHHHCCCHHHCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEE
VTLEGTRPMLVEIQALVDEGGPSPRRLSVGLERDRLAMLLAVLHRHAGVACMDQDVFVNA
EEECCCCCHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCEEECCCEEEEE
VGGVRISEPAADLAVMLAITSSLRGKPLPKGFIAFGEVGLAGEVRPAPRGQERLKEAAKL
CCCEEECCCHHHHHHHHHHHHHHCCCCCCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHC
GFTMAVVPKANAPRKPIEGLTIHAVERVEEAMEVVRGMG
CEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKDKTVFTCTECGGTSPRWLGKCPACGAWNTLVESVAEAGPGKNRYSTPQHAGLAQSQA
CCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHC
VTPLSAIEAADVARTASGIEELDRVLGGGVVEGGVVLIGGDPGIGKSTLLLQALDALQRL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHC
GLPTLYVTGEESGAQVALRSRRLGLDHSQVNVLAEIQLEKILATVEATQPAVAVIDSIQT
CCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VYSDQLTSAPGSVAQVRECAAHLTRAAKATGVSIILVGHVTKEGALAGPRVLEHMVDTVL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHHHHHHHEE
YFEGDTHSQFRLVRAIKNRFGAVNEIGVFAMTEKGLKGVTNPSAIFLSQHSEPVPGSCVL
EECCCCHHHHHHHHHHHHHCCCHHHCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEE
VTLEGTRPMLVEIQALVDEGGPSPRRLSVGLERDRLAMLLAVLHRHAGVACMDQDVFVNA
EEECCCCCHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCEEECCCEEEEE
VGGVRISEPAADLAVMLAITSSLRGKPLPKGFIAFGEVGLAGEVRPAPRGQERLKEAAKL
CCCEEECCCHHHHHHHHHHHHHHCCCCCCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHC
GFTMAVVPKANAPRKPIEGLTIHAVERVEEAMEVVRGMG
CEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]