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The map label for this gene is metH [H]

Identifier: 120608921

GI number: 120608921

Start: 236529

End: 239252

Strand: Direct

Name: metH [H]

Synonym: Aave_0214

Alternate gene names: 120608921

Gene position: 236529-239252 (Clockwise)

Preceding gene: 120608920

Following gene: 120608922

Centisome position: 4.42

GC content: 67.07

Gene sequence:

>2724_bases
ATGTCCGCCCCCCATTCCCTTCCTCCCATGAAGCTGTCCGGCCTGGAGCCGGTTTCCATCGGCGAGGGCACGCTGTTCGT
CAACATCGGCGAGCGCACCAACGTGACGGGCTCCAAGGCCTTCGCGCGCATGATCCTCAACGGCCAGTACGAAGAGGCCC
TGGCCGTGGCGCGCCAGCAGGTGGAGAACGGCGCCCAGGTCATCGACATCAACATGGACGAGGCCATGCTCGACAGCAAG
GCCGCCATGGTGCGCTTCCTGCAGCTCATCGCCTCCGAGCCCGACATCGCCCGCGTGCCCATCATGGTGGACTCCTCCAA
GTGGGACGTGATCGAGGCCGGCCTGCGCTGCATCCAGGGCAAGGGCATCGTCAACTCCATCAGCATGAAAGAGGGCGTGG
AGAAGTTCAAGCACGAGGCGCGCCTCGTCAAGCGCTACGGCGCCGCCGCCGTGGTCATGGCCTTCGACGAGGTGGGGCAG
GCCGACACCTACGCGCGCAAGATCGAGATCTGCGAGCGCGCCTACCGCGTGCTGGTCGATGAAGTCGGCTTCCCGCCCGA
GGACATCATCTTCGACCCCAACATCTTCGCGGTGGCCACGGGCATCGAGGAGCACAACAACTACGCGGTGGATTTCATCG
AGGCCACGCGCTGGATCAAGCAGAACCTGCCGGGCGCCAAGGTGTCGGGCGGCGTCTCCAACGTGTCCTTCAGCTTCCGC
GGCAACGACCCGGTGCGCGAGGCCATCCACACCGTGTTCCTCTACCACGCCATCAAGGCCGGCATGGACATGGGCATCGT
CAACGCCGGCATGGTGGGCGTCTATGACGACCTGGAGCCCACCCTGCGCGAACGCGTGGAAGACGTGGTGCTCAACCGCC
GGCCCGATGCGGGCGAACGCCTGGTGGAGATCGCCGAGACCGCCAAGAGCGGCGCCAAGGACGAGAGCCGGAAGCTCGAA
TGGCGCAACGCCCCGGTGCGCGAGCGGCTCGCCCATGCGCTGGTGCACGGCATCACCGACTTCATCGTGGAGGACACGGA
AGAGGCCTACCGGGAGATCCTGGCCGGGGGCGGCCGCCCGCTGCACGTGATCGAAGGCCCGCTCATGGACGGCATGAACA
TCGTGGGCGACCTGTTCGGCGCCGGCAAGATGTTCCTGCCCCAGGTGGTGAAAAGCGCGCGCGTGATGAAGTCCGCCGTG
GCCCACCTGATCCCCTACATCGAGGAAGAAAAGCGCCAGGACGAACTCGCCGGCCGCGACGTGCGCAGCAAGGGAAAGAT
CGTCATCGCCACCGTGAAGGGCGACGTGCACGACATCGGCAAGAACATCGTCACCGTGGTCCTGCAGTGCAACAACTTCG
AGGTGGTGAACATGGGCGTGATGGTCCCGTGCCACGAGATCCTCGCCAGGGCCAAGGTCGAGGGCGCGGACATCGTGGGC
CTGTCGGGCCTCATCACGCCCAGCCTGGAAGAGATGCAGTACGTGGCCGGCGAGATGCAGAAGGACGACCACTTCCGCGT
CCGGAAGATCCCGCTCCTGATCGGCGGCGCCACCTGCTCGCGCGTGCACACCGCCGTCAAGATCGCGCCGCACTACGAAG
GCCCCGTGGTGTATGTGCCCGACGCCTCGCGCAGCGTGAGCGTGGCGCAGAGCCTGCTGGGCGACGGCGCGCAGAGCTAC
GTCGATGAGCTGAACGCCGACTACGACAAGGTGCGCCAGCAGCACGCCAACAGGAAGCAGACGCCGATGTGGCCGCTGGC
CAAGGCACGCGCCAACCGCACGCCCGTCAACTTCAGCACCTACCAGCCGCAGCCGCCCCGCCTGCTGGGCCGCCGCGTGT
TCAAGAACTTCGACCTGGGCGAGCTGGCCAGATACATCGACTGGGGCCCCTTCTTCCAGACCTGGGACCTGGCCGGCCCG
TACCCCGCCATCCTCGACGACGAGGTGGTGGGCGAGCAGGCCCGCCGCGTCTTCGCCGACGGCCAGGCCATGCTCAGGAA
GATCATCGAAGGCCGCTGGCTCAGCGCGAGCGGCGTGCTGGCGCTCTACCCCGCCAACAGCGTGGGCGACGACATCGAGT
TCTACACCGACGCATCGCGCACCGAAGTCGCCATGACCTGGTACGGCCTGCGCCAGCAGACCGAAAAGCAGGTGATCGAC
GGCGTGATGCGCCCCAGCCGGTGCCTGGCCGACTTCGTCGCGCCCAAGGAGAGCGGCATCGCCGACTACGCCGGCCTTTT
CGCCGTGACGGCCGGCCTGGGCGTGGAGAAGAAGGAACAGGCCTTCATCGACGCGCTGGACGACTACTCCGCCATCATGC
TCAAGGGCCTGGCCGACCGCCTCGCCGAAGCCTTCGCCGAATGCCTGCACCAGCGCGTGCGCACCGACCTCTGGGGCTAT
GCGGCCGGCGAGCAGCTGACCAACGAAGAGATGATCGCCGAGAAGTACCAGGGCATCCGCCCCGCGCCCGGCTACCCCGC
CTGCCCGGACCACAGCGCCAAGACCGACCTCTTCCGCGTGCTGCAGTGCGAGGAGATCGGCATGGGCCTGACGGAAAGCC
TGGCCATGACCCCCGCCGCCAGCGTGAGCGGCTTCTACATCGGCCACCCCGAGAGCACGTACTTCAACGTCGGCAAGATC
GGGGAGGACCAGCTGCACGACATGGCCGAGCGGCGCGGGATGGACGAGAAGGTGCTGGAGCGGCTGCTGGCGCCGAATCT
CTGA

Upstream 100 bases:

>100_bases
CGACCGCCGCGGGCGCGCCGTCAGGCTCGGAGCCCGTGCCGAAGAATCGATGCCAACGACGCTCACCTGTCCTTTCCCAC
CGTCCGCGCAGGTGAGCCCC

Downstream 100 bases:

>100_bases
TTTGCGTCCTGCCCCGGAAAAGACGAAGGCCCCGCATGCGGGGCCTTCCATTTGGTGCATCTTTCAGCTTGTTAGCGTCC
AGAGCGCATATCCCAGTGAT

Product: methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 907; Mature: 906

Protein sequence:

>907_residues
MSAPHSLPPMKLSGLEPVSIGEGTLFVNIGERTNVTGSKAFARMILNGQYEEALAVARQQVENGAQVIDINMDEAMLDSK
AAMVRFLQLIASEPDIARVPIMVDSSKWDVIEAGLRCIQGKGIVNSISMKEGVEKFKHEARLVKRYGAAAVVMAFDEVGQ
ADTYARKIEICERAYRVLVDEVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFIEATRWIKQNLPGAKVSGGVSNVSFSFR
GNDPVREAIHTVFLYHAIKAGMDMGIVNAGMVGVYDDLEPTLRERVEDVVLNRRPDAGERLVEIAETAKSGAKDESRKLE
WRNAPVRERLAHALVHGITDFIVEDTEEAYREILAGGGRPLHVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKSAV
AHLIPYIEEEKRQDELAGRDVRSKGKIVIATVKGDVHDIGKNIVTVVLQCNNFEVVNMGVMVPCHEILARAKVEGADIVG
LSGLITPSLEEMQYVAGEMQKDDHFRVRKIPLLIGGATCSRVHTAVKIAPHYEGPVVYVPDASRSVSVAQSLLGDGAQSY
VDELNADYDKVRQQHANRKQTPMWPLAKARANRTPVNFSTYQPQPPRLLGRRVFKNFDLGELARYIDWGPFFQTWDLAGP
YPAILDDEVVGEQARRVFADGQAMLRKIIEGRWLSASGVLALYPANSVGDDIEFYTDASRTEVAMTWYGLRQQTEKQVID
GVMRPSRCLADFVAPKESGIADYAGLFAVTAGLGVEKKEQAFIDALDDYSAIMLKGLADRLAEAFAECLHQRVRTDLWGY
AAGEQLTNEEMIAEKYQGIRPAPGYPACPDHSAKTDLFRVLQCEEIGMGLTESLAMTPAASVSGFYIGHPESTYFNVGKI
GEDQLHDMAERRGMDEKVLERLLAPNL

Sequences:

>Translated_907_residues
MSAPHSLPPMKLSGLEPVSIGEGTLFVNIGERTNVTGSKAFARMILNGQYEEALAVARQQVENGAQVIDINMDEAMLDSK
AAMVRFLQLIASEPDIARVPIMVDSSKWDVIEAGLRCIQGKGIVNSISMKEGVEKFKHEARLVKRYGAAAVVMAFDEVGQ
ADTYARKIEICERAYRVLVDEVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFIEATRWIKQNLPGAKVSGGVSNVSFSFR
GNDPVREAIHTVFLYHAIKAGMDMGIVNAGMVGVYDDLEPTLRERVEDVVLNRRPDAGERLVEIAETAKSGAKDESRKLE
WRNAPVRERLAHALVHGITDFIVEDTEEAYREILAGGGRPLHVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKSAV
AHLIPYIEEEKRQDELAGRDVRSKGKIVIATVKGDVHDIGKNIVTVVLQCNNFEVVNMGVMVPCHEILARAKVEGADIVG
LSGLITPSLEEMQYVAGEMQKDDHFRVRKIPLLIGGATCSRVHTAVKIAPHYEGPVVYVPDASRSVSVAQSLLGDGAQSY
VDELNADYDKVRQQHANRKQTPMWPLAKARANRTPVNFSTYQPQPPRLLGRRVFKNFDLGELARYIDWGPFFQTWDLAGP
YPAILDDEVVGEQARRVFADGQAMLRKIIEGRWLSASGVLALYPANSVGDDIEFYTDASRTEVAMTWYGLRQQTEKQVID
GVMRPSRCLADFVAPKESGIADYAGLFAVTAGLGVEKKEQAFIDALDDYSAIMLKGLADRLAEAFAECLHQRVRTDLWGY
AAGEQLTNEEMIAEKYQGIRPAPGYPACPDHSAKTDLFRVLQCEEIGMGLTESLAMTPAASVSGFYIGHPESTYFNVGKI
GEDQLHDMAERRGMDEKVLERLLAPNL
>Mature_906_residues
SAPHSLPPMKLSGLEPVSIGEGTLFVNIGERTNVTGSKAFARMILNGQYEEALAVARQQVENGAQVIDINMDEAMLDSKA
AMVRFLQLIASEPDIARVPIMVDSSKWDVIEAGLRCIQGKGIVNSISMKEGVEKFKHEARLVKRYGAAAVVMAFDEVGQA
DTYARKIEICERAYRVLVDEVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFIEATRWIKQNLPGAKVSGGVSNVSFSFRG
NDPVREAIHTVFLYHAIKAGMDMGIVNAGMVGVYDDLEPTLRERVEDVVLNRRPDAGERLVEIAETAKSGAKDESRKLEW
RNAPVRERLAHALVHGITDFIVEDTEEAYREILAGGGRPLHVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKSAVA
HLIPYIEEEKRQDELAGRDVRSKGKIVIATVKGDVHDIGKNIVTVVLQCNNFEVVNMGVMVPCHEILARAKVEGADIVGL
SGLITPSLEEMQYVAGEMQKDDHFRVRKIPLLIGGATCSRVHTAVKIAPHYEGPVVYVPDASRSVSVAQSLLGDGAQSYV
DELNADYDKVRQQHANRKQTPMWPLAKARANRTPVNFSTYQPQPPRLLGRRVFKNFDLGELARYIDWGPFFQTWDLAGPY
PAILDDEVVGEQARRVFADGQAMLRKIIEGRWLSASGVLALYPANSVGDDIEFYTDASRTEVAMTWYGLRQQTEKQVIDG
VMRPSRCLADFVAPKESGIADYAGLFAVTAGLGVEKKEQAFIDALDDYSAIMLKGLADRLAEAFAECLHQRVRTDLWGYA
AGEQLTNEEMIAEKYQGIRPAPGYPACPDHSAKTDLFRVLQCEEIGMGLTESLAMTPAASVSGFYIGHPESTYFNVGKIG
EDQLHDMAERRGMDEKVLERLLAPNL

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=914, Percent_Identity=54.4857768052516, Blast_Score=961, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=915, Percent_Identity=61.0928961748634, Blast_Score=1077, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535405, Length=918, Percent_Identity=54.2483660130719, Blast_Score=949, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 99982; Mature: 99851

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPHSLPPMKLSGLEPVSIGEGTLFVNIGERTNVTGSKAFARMILNGQYEEALAVARQQ
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
VENGAQVIDINMDEAMLDSKAAMVRFLQLIASEPDIARVPIMVDSSKWDVIEAGLRCIQG
HHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCC
KGIVNSISMKEGVEKFKHEARLVKRYGAAAVVMAFDEVGQADTYARKIEICERAYRVLVD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHH
EVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFIEATRWIKQNLPGAKVSGGVSNVSFSFR
HCCCCCHHEEECCCCEEEEECHHHCCCEEEHHHHHHHHHHHCCCCCEECCCCCEEEEEEC
GNDPVREAIHTVFLYHAIKAGMDMGIVNAGMVGVYDDLEPTLRERVEDVVLNRRPDAGER
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHH
LVEIAETAKSGAKDESRKLEWRNAPVRERLAHALVHGITDFIVEDTEEAYREILAGGGRP
HHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCE
LHVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKSAVAHLIPYIEEEKRQDELAGRD
EEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VRSKGKIVIATVKGDVHDIGKNIVTVVLQCNNFEVVNMGVMVPCHEILARAKVEGADIVG
CCCCCCEEEEEECCCHHHHHHHHEEEEEECCCEEEEECCEECCHHHHHHHHHCCCCCEEC
LSGLITPSLEEMQYVAGEMQKDDHFRVRKIPLLIGGATCSRVHTAVKIAPHYEGPVVYVP
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHEEEECCCCCCEEECC
DASRSVSVAQSLLGDGAQSYVDELNADYDKVRQQHANRKQTPMWPLAKARANRTPVNFST
CCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCC
YQPQPPRLLGRRVFKNFDLGELARYIDWGPFFQTWDLAGPYPAILDDEVVGEQARRVFAD
CCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GQAMLRKIIEGRWLSASGVLALYPANSVGDDIEFYTDASRTEVAMTWYGLRQQTEKQVID
HHHHHHHHHCCCEECCCCEEEEECCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHH
GVMRPSRCLADFVAPKESGIADYAGLFAVTAGLGVEKKEQAFIDALDDYSAIMLKGLADR
HHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAEAFAECLHQRVRTDLWGYAAGEQLTNEEMIAEKYQGIRPAPGYPACPDHSAKTDLFRV
HHHHHHHHHHHHHHHHHHCCCCCCHHCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
LQCEEIGMGLTESLAMTPAASVSGFYIGHPESTYFNVGKIGEDQLHDMAERRGMDEKVLE
HHHHHHCCCHHHHHHCCCCCCCCCEEECCCCCCEEECCCCCHHHHHHHHHHCCCCHHHHH
RLLAPNL
HHHCCCC
>Mature Secondary Structure 
SAPHSLPPMKLSGLEPVSIGEGTLFVNIGERTNVTGSKAFARMILNGQYEEALAVARQQ
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
VENGAQVIDINMDEAMLDSKAAMVRFLQLIASEPDIARVPIMVDSSKWDVIEAGLRCIQG
HHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCC
KGIVNSISMKEGVEKFKHEARLVKRYGAAAVVMAFDEVGQADTYARKIEICERAYRVLVD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHH
EVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFIEATRWIKQNLPGAKVSGGVSNVSFSFR
HCCCCCHHEEECCCCEEEEECHHHCCCEEEHHHHHHHHHHHCCCCCEECCCCCEEEEEEC
GNDPVREAIHTVFLYHAIKAGMDMGIVNAGMVGVYDDLEPTLRERVEDVVLNRRPDAGER
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHH
LVEIAETAKSGAKDESRKLEWRNAPVRERLAHALVHGITDFIVEDTEEAYREILAGGGRP
HHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCE
LHVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKSAVAHLIPYIEEEKRQDELAGRD
EEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VRSKGKIVIATVKGDVHDIGKNIVTVVLQCNNFEVVNMGVMVPCHEILARAKVEGADIVG
CCCCCCEEEEEECCCHHHHHHHHEEEEEECCCEEEEECCEECCHHHHHHHHHCCCCCEEC
LSGLITPSLEEMQYVAGEMQKDDHFRVRKIPLLIGGATCSRVHTAVKIAPHYEGPVVYVP
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHEEEECCCCCCEEECC
DASRSVSVAQSLLGDGAQSYVDELNADYDKVRQQHANRKQTPMWPLAKARANRTPVNFST
CCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCC
YQPQPPRLLGRRVFKNFDLGELARYIDWGPFFQTWDLAGPYPAILDDEVVGEQARRVFAD
CCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GQAMLRKIIEGRWLSASGVLALYPANSVGDDIEFYTDASRTEVAMTWYGLRQQTEKQVID
HHHHHHHHHCCCEECCCCEEEEECCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHH
GVMRPSRCLADFVAPKESGIADYAGLFAVTAGLGVEKKEQAFIDALDDYSAIMLKGLADR
HHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAEAFAECLHQRVRTDLWGYAAGEQLTNEEMIAEKYQGIRPAPGYPACPDHSAKTDLFRV
HHHHHHHHHHHHHHHHHHCCCCCCHHCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
LQCEEIGMGLTESLAMTPAASVSGFYIGHPESTYFNVGKIGEDQLHDMAERRGMDEKVLE
HHHHHHCCCHHHHHHCCCCCCCCCEEECCCCCCEEECCCCCHHHHHHHHHHCCCCHHHHH
RLLAPNL
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]