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The map label for this gene is ycgM [C]

Identifier: 120608855

GI number: 120608855

Start: 162127

End: 162825

Strand: Direct

Name: ycgM [C]

Synonym: Aave_0147

Alternate gene names: 120608855

Gene position: 162127-162825 (Clockwise)

Preceding gene: 120608854

Following gene: 120608856

Centisome position: 3.03

GC content: 69.53

Gene sequence:

>699_bases
ATGGCTTTCGTGTTTCCTGTTCCTCCTACCGTGGCCGTGCCTGTCGTGGGCACATCGGATGCCTTCGCCGTGCGGCGCGT
CTATTGCGTGGGGCGCAACTACGCGGCCCATGCGCGGGAGATGGGGTTCGATCCGGACCGCGAGCCGCCGTTCTTCTTCT
GCAAGCCGGCCGATGCGGTGCTTCCCGTGGCCTATGGCGAGACGCTGCGGCTGCCGTATCCGGTGCGCACCGACAACTTC
CATTACGAGGCGGAGCTGGTGGTCGCCATCGGCAAGGCGGGCAGCGACATCGCCCGCGAGAACGCGCTGGAGCATGCCTG
GGGCTACGCCGTGGGCCTGGACATGACCCGCCGCGACCGGCAGATGGAGATGCGCCAGATGGGCCGCCCGTGGGAGATCG
GCAAGGCCTTCGATGCCTCCGCGCCGATCGGCCCGATCCACCGCGCGAGCGACGTGGGCCACTTCGAGCAGGCCGGCCTC
TGGCTCACCGTGAACGGCGCGGACCGACAGCGCAGCGACGTGTCGCACCTGATCTGGTCGGTGGCCGAGACCATCGCGGA
CCTCTCCACGTATTTCCGCCTGGAGCCCGGCGACCTGATCTACACCGGCACGCCCGAAGGCGTGGGCCCGGTGGTGCGCG
GCGACCGCATGGTGGTGGGCGTGGAGCGCCTGGGCGAGCTGGCGGTGGACGTGGTCTGA

Upstream 100 bases:

>100_bases
TCTGCGATGCGGCGCCTTGCCAGCAGGGCTCTGTGGACCGCTCACGAGCGTGACCCGCCTTCCTCTTTGAACGATCCATT
TCCCCGAAAGAAAAAACACC

Downstream 100 bases:

>100_bases
GGCGACGGCGACGCCATGCAGCTCTACAGCTTTTTCAACAGCTCCACCTCGTACCGGGTGCGCATCGCGCTGGCGCTCAA
GGGGCTGCCGGCCGACTACC

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAFVFPVPPTVAVPVVGTSDAFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVLPVAYGETLRLPYPVRTDNF
HYEAELVVAIGKAGSDIARENALEHAWGYAVGLDMTRRDRQMEMRQMGRPWEIGKAFDASAPIGPIHRASDVGHFEQAGL
WLTVNGADRQRSDVSHLIWSVAETIADLSTYFRLEPGDLIYTGTPEGVGPVVRGDRMVVGVERLGELAVDVV

Sequences:

>Translated_232_residues
MAFVFPVPPTVAVPVVGTSDAFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVLPVAYGETLRLPYPVRTDNF
HYEAELVVAIGKAGSDIARENALEHAWGYAVGLDMTRRDRQMEMRQMGRPWEIGKAFDASAPIGPIHRASDVGHFEQAGL
WLTVNGADRQRSDVSHLIWSVAETIADLSTYFRLEPGDLIYTGTPEGVGPVVRGDRMVVGVERLGELAVDVV
>Mature_231_residues
AFVFPVPPTVAVPVVGTSDAFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVLPVAYGETLRLPYPVRTDNFH
YEAELVVAIGKAGSDIARENALEHAWGYAVGLDMTRRDRQMEMRQMGRPWEIGKAFDASAPIGPIHRASDVGHFEQAGLW
LTVNGADRQRSDVSHLIWSVAETIADLSTYFRLEPGDLIYTGTPEGVGPVVRGDRMVVGVERLGELAVDVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=38.6473429951691, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=38.7254901960784, Blast_Score=141, Evalue=5e-34,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=39.5, Blast_Score=141, Evalue=5e-34,
Organism=Homo sapiens, GI156231349, Length=215, Percent_Identity=33.953488372093, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI40786394, Length=215, Percent_Identity=33.4883720930233, Blast_Score=107, Evalue=7e-24,
Organism=Escherichia coli, GI1787428, Length=201, Percent_Identity=39.8009950248756, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=36.2244897959184, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324161, Length=237, Percent_Identity=28.6919831223629, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28571789, Length=212, Percent_Identity=33.4905660377358, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28572127, Length=186, Percent_Identity=32.7956989247312, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24663695, Length=222, Percent_Identity=27.4774774774775, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25560; Mature: 25429

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFVFPVPPTVAVPVVGTSDAFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAV
CEEEECCCCCEEEEEECCCCHHHHEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
LPVAYGETLRLPYPVRTDNFHYEAELVVAIGKAGSDIARENALEHAWGYAVGLDMTRRDR
EEEECCCEEECCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCEEEECCCHHHHH
QMEMRQMGRPWEIGKAFDASAPIGPIHRASDVGHFEQAGLWLTVNGADRQRSDVSHLIWS
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCHHHHHHHHHH
VAETIADLSTYFRLEPGDLIYTGTPEGVGPVVRGDRMVVGVERLGELAVDVV
HHHHHHHHHHHEEECCCCEEEECCCCCCCCEECCCEEEEEHHHHHHHHCCCC
>Mature Secondary Structure 
AFVFPVPPTVAVPVVGTSDAFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAV
EEEECCCCCEEEEEECCCCHHHHEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
LPVAYGETLRLPYPVRTDNFHYEAELVVAIGKAGSDIARENALEHAWGYAVGLDMTRRDR
EEEECCCEEECCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCEEEECCCHHHHH
QMEMRQMGRPWEIGKAFDASAPIGPIHRASDVGHFEQAGLWLTVNGADRQRSDVSHLIWS
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCHHHHHHHHHH
VAETIADLSTYFRLEPGDLIYTGTPEGVGPVVRGDRMVVGVERLGELAVDVV
HHHHHHHHHHHEEECCCCEEEECCCCCCCCEECCCEEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]