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The map label for this gene is 120608854

Identifier: 120608854

GI number: 120608854

Start: 160851

End: 161963

Strand: Direct

Name: 120608854

Synonym: Aave_0146

Alternate gene names: NA

Gene position: 160851-161963 (Clockwise)

Preceding gene: 120608845

Following gene: 120608855

Centisome position: 3.01

GC content: 71.79

Gene sequence:

>1113_bases
ATGGACACCACCCTCGCCCGGCCCGCAGCACAGGGCGCCACCCCGGCCGCTGCTCCGGCATCGGCTCCGCCGCACCGGAC
GCCGTCACCGGAACGCCAGGCCTACTACGACCGCATCGCCGGCCACGACATGGCCCCCCTGTGGGAATCGCTGCACAGCC
TCGTGCCGCGCGAGCCGCGTCCGCAGGCCGTGCCCGCCTTCTGGAAATACGACGACGTGCGCCCGCTGGTCATGCAGGCC
GGCGAGGTCATCAGCGCCGAAGAGGCCGTGCGCCGCGTGCTCATCCTGGAGAACCCGGGCCTGCCGGGCCGCTCCAGCAT
CACGTCCACGCTGTACGCGGGGCTGCAGCTGATCCTGCCGGGCGAGGTGGCGCCCAGCCACCGCCACACGCAGTCGGCGC
TGCGCTTCATCGTGGAAGGCAAGGGCGCCTACACGGCCGTCAACGGCGAGCGCACCACCATGCACCCGGGCGATTTCATC
ATCACCCCGTCGTGGACCTGGCACGACCACGGCAACCCCGCGGTGGACGAGGGTGGCGAGCCCGTGGTGTGGCTCGACGG
CCTGGACATTCCCCTGATCGGCCACCTGGACGCCGGCTTCGCCGAGAACTACCCCGAGGCCGTGCAGCCGGTGAGCCGCG
CCGAAGGCCACAGCTTCGCCGCCTTCGGCCACAACATGGCACCCGTGCGCCACCGCGCGGCCGGCCCGACCTCGCCGATC
TTCAGCTACCCCTACGACCGCAGCCGCGAGGCGCTGGACCGGCTGTTCCGCCAGGGCGAACTCGATGCGTGGGACGGCGT
GAAGCTGCGCTACGTGAACCCCGCCACCGGCGGCTGGCCCATGCCCACCATGGCCACCTTCCTGCAGTTGCTGCCCGCGG
GCTTCCAGGGCCGCACCTACCGCGGCACCGACGCCACCGTGTTCAGCGTGGTCGAAGGCCAGGGCACGGCGCGCATCGGC
GGCAGCACCTTCCAGTTCGGCCCGCGCGACACCTTCGTCGCGCCGTCGTGGGCGCCGGTGCAGCTGGCCGCCACGCAGGA
CGCGGTGCTGTTCAGCTATTCCGACCGGCCGGTGCAAGTAGCACTCAACCTCCACCGCGAACACCGCATGTGA

Upstream 100 bases:

>100_bases
GATTTTACGGACTATCGCTCGCCTCGAATAATGGACTCCATGGCACGGCCGAGCCTTCCCCCCGAGGGCACGACGCCGGG
CCGCTGCCAAGGAGACAACC

Downstream 100 bases:

>100_bases
CGGGGCGCGGTCCACAGAGCCTCTCTGGCGGCGTTGCCGCATCTTGCCGTGGCGCTGCCACTGTCTGCGATGCGGCGCCT
TGCCAGCAGGGCTCTGTGGA

Product: gentisate 1,2-dioxygenase

Products: maleylpyruvate

Alternate protein names: Cupin 2 Domain-Containing Protein; Cupin 2 Conserved Barrel Domain Protein; Cupin 2 Barrel; Gentisate 1 2-Dioxygenase Oxidoreductase; Cupin 2 Conserved Barrel Domain-Containing Protein; 1 2-Dioxygenase; Dioxygenase Oxidoreductase Protein; Gentisate 1 2-Dioxygenase Oxidoreductase Protein; Dioxygenase; Cupin 2 Protein; 1-Hydroxy-2-Naphthoate Dioxygenase

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MDTTLARPAAQGATPAAAPASAPPHRTPSPERQAYYDRIAGHDMAPLWESLHSLVPREPRPQAVPAFWKYDDVRPLVMQA
GEVISAEEAVRRVLILENPGLPGRSSITSTLYAGLQLILPGEVAPSHRHTQSALRFIVEGKGAYTAVNGERTTMHPGDFI
ITPSWTWHDHGNPAVDEGGEPVVWLDGLDIPLIGHLDAGFAENYPEAVQPVSRAEGHSFAAFGHNMAPVRHRAAGPTSPI
FSYPYDRSREALDRLFRQGELDAWDGVKLRYVNPATGGWPMPTMATFLQLLPAGFQGRTYRGTDATVFSVVEGQGTARIG
GSTFQFGPRDTFVAPSWAPVQLAATQDAVLFSYSDRPVQVALNLHREHRM

Sequences:

>Translated_370_residues
MDTTLARPAAQGATPAAAPASAPPHRTPSPERQAYYDRIAGHDMAPLWESLHSLVPREPRPQAVPAFWKYDDVRPLVMQA
GEVISAEEAVRRVLILENPGLPGRSSITSTLYAGLQLILPGEVAPSHRHTQSALRFIVEGKGAYTAVNGERTTMHPGDFI
ITPSWTWHDHGNPAVDEGGEPVVWLDGLDIPLIGHLDAGFAENYPEAVQPVSRAEGHSFAAFGHNMAPVRHRAAGPTSPI
FSYPYDRSREALDRLFRQGELDAWDGVKLRYVNPATGGWPMPTMATFLQLLPAGFQGRTYRGTDATVFSVVEGQGTARIG
GSTFQFGPRDTFVAPSWAPVQLAATQDAVLFSYSDRPVQVALNLHREHRM
>Mature_370_residues
MDTTLARPAAQGATPAAAPASAPPHRTPSPERQAYYDRIAGHDMAPLWESLHSLVPREPRPQAVPAFWKYDDVRPLVMQA
GEVISAEEAVRRVLILENPGLPGRSSITSTLYAGLQLILPGEVAPSHRHTQSALRFIVEGKGAYTAVNGERTTMHPGDFI
ITPSWTWHDHGNPAVDEGGEPVVWLDGLDIPLIGHLDAGFAENYPEAVQPVSRAEGHSFAAFGHNMAPVRHRAAGPTSPI
FSYPYDRSREALDRLFRQGELDAWDGVKLRYVNPATGGWPMPTMATFLQLLPAGFQGRTYRGTDATVFSVVEGQGTARIG
GSTFQFGPRDTFVAPSWAPVQLAATQDAVLFSYSDRPVQVALNLHREHRM

Specific function: Unknown

COG id: COG3435

COG function: function code Q; Gentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.13.11.4

Molecular weight: Translated: 40377; Mature: 40377

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTTLARPAAQGATPAAAPASAPPHRTPSPERQAYYDRIAGHDMAPLWESLHSLVPREPR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
PQAVPAFWKYDDVRPLVMQAGEVISAEEAVRRVLILENPGLPGRSSITSTLYAGLQLILP
CCCCCCEECCCCCCHHHHHCCCCCCHHHHHCEEEEEECCCCCCHHHHHHHHHHCEEEEEC
GEVAPSHRHTQSALRFIVEGKGAYTAVNGERTTMHPGDFIITPSWTWHDHGNPAVDEGGE
CCCCCCHHHHHHHHHHHEECCCCEEEECCCCEEECCCCEEECCCEEECCCCCCCCCCCCC
PVVWLDGLDIPLIGHLDAGFAENYPEAVQPVSRAEGHSFAAFGHNMAPVRHRAAGPTSPI
EEEEECCCCCCEEECCCCCHHCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCCCCC
FSYPYDRSREALDRLFRQGELDAWDGVKLRYVNPATGGWPMPTMATFLQLLPAGFQGRTY
CCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEE
RGTDATVFSVVEGQGTARIGGSTFQFGPRDTFVAPSWAPVQLAATQDAVLFSYSDRPVQV
CCCCCEEEEEEECCCCEEECCCEEECCCCCCEECCCCCCEEEEECCCEEEEEECCCCEEE
ALNLHREHRM
EEEHHHHCCC
>Mature Secondary Structure
MDTTLARPAAQGATPAAAPASAPPHRTPSPERQAYYDRIAGHDMAPLWESLHSLVPREPR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
PQAVPAFWKYDDVRPLVMQAGEVISAEEAVRRVLILENPGLPGRSSITSTLYAGLQLILP
CCCCCCEECCCCCCHHHHHCCCCCCHHHHHCEEEEEECCCCCCHHHHHHHHHHCEEEEEC
GEVAPSHRHTQSALRFIVEGKGAYTAVNGERTTMHPGDFIITPSWTWHDHGNPAVDEGGE
CCCCCCHHHHHHHHHHHEECCCCEEEECCCCEEECCCCEEECCCEEECCCCCCCCCCCCC
PVVWLDGLDIPLIGHLDAGFAENYPEAVQPVSRAEGHSFAAFGHNMAPVRHRAAGPTSPI
EEEEECCCCCCEEECCCCCHHCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCCCCC
FSYPYDRSREALDRLFRQGELDAWDGVKLRYVNPATGGWPMPTMATFLQLLPAGFQGRTY
CCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEE
RGTDATVFSVVEGQGTARIGGSTFQFGPRDTFVAPSWAPVQLAATQDAVLFSYSDRPVQV
CCCCCEEEEEEECCCCEEECCCEEECCCCCCEECCCCCCEEEEECCCEEEEEECCCCEEE
ALNLHREHRM
EEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2,5-dihydroxybenzoate; O2

Specific reaction: 2,5-dihydroxybenzoate + O2 = maleylpyruvate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA