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The map label for this gene is cbiD

Identifier: 120608781

GI number: 120608781

Start: 78983

End: 80110

Strand: Direct

Name: cbiD

Synonym: Aave_0071

Alternate gene names: 120608781

Gene position: 78983-80110 (Clockwise)

Preceding gene: 120608780

Following gene: 120608782

Centisome position: 1.48

GC content: 72.25

Gene sequence:

>1128_bases
ATGATGGAGAAAACCGTCCGCCGCGGCACGCGCACCGGCTTCACCACCGGGGCCTGCTCCGCCGCCGCCGCGCGCGCCGC
CGTGCTGGGCCTGGTCGAAGGTGCCGTGCCCGAGGCGGTGGACTGCCTGCTGCCCAATGGGGACGTGGTGCGCTTCGCGG
TGAATGACGGAGCCTGCGAAGCTGGCCAGGCCGCGCACGCCATGGTCATCAAGGACGCGGGCGACGACCCCGATTGCACC
GACAAGGCCCACCTCACCGCCGACGTGCGCGTGCTGCCCGGCCGAGCGGGCGAGGTCGTGCTGTGCGGCGGCTTCGGCGT
GGGCACGGTCACCATGGCCGGCCTGGGCCTGGAAGTGGGCGGCCCGGCCATCAATCCCGTGCCCCGCCGCAACATCGAGG
AGAACGTGCGCGCCGTGGGCGGCCCGCTGCTCGCGAACGCGGGGATCGAAGTGACCATCTCCGTGCCCCAGGGCGTGGAA
ATGGCCAGGAAGACGCTCAACGCGCGCCTCGGCATCCTGGGCGGCATCTCCATCCTGGGCACCACGGGCATCGTCAAGCC
GTATTCCACGTCCGCCTACCGCGCCAGCGTGGTGCAGGGCGTGCAGGTGGCGGCCACGCTCGGCCATGGCGTGGTGGTGC
TGACCACGGGCGGGCGCACCGAGCAGTTCGCGATGAAGGAGCGGCCCGAGCTGCCCGCCGCCTGCTTCGTGCAGATGGGC
GACTTCCTGCGCTACGCGCTGGACGAGGCCGTGGCGCAGGGCCTGCGCGAAGTAGTCATCGGCGGCATGGTGGGCAAGCT
CACGAAGATCGCCCAGGGCGAGACGATCACCCACGCCAACCGCGCCGAGGTCGATACCCAGTTGCTGGCCGAACTGGCCG
CCCGCGTGGGCGCGCCGCCCGACGTGTGCGCCGAGATCGCCGCCGCCGAGACCGCGCGCTTCGGCGCCGAGCGCATGCAG
GCCCTGGGCCTGGGCGAGCCCTTCCACCATGCGCTCGCCCAGGCCGTGGTGCAGACGCTGACCGCGCCCGACCGCTACGG
CGACCGCTTCCACCTCACCGTGCTGGTCTGCGATTTCGACGGCAGCAAGATCACCGAAGCCGCCTCCGGGCCGGCTGCCA
CCGCATGA

Upstream 100 bases:

>100_bases
CTGCACGCGCTGCTGGCGCTGGCCGAGGCGCGGCAGAAGCAACAACCGCAGCAGCCCGCACAGGGGCCGGCACGGAGCGC
CACCGGAGGCTGAACCCGCC

Downstream 100 bases:

>100_bases
CGATGACCACCACGAACCTGCTCGAAAAAGACCCCCAGCCCTGCCGCGTGATCGGCGTGCTGGACGATGGCGCCGCCAGC
CTGAGCGCCACCGCGCTCGC

Product: cobalt-precorrin-6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MMEKTVRRGTRTGFTTGACSAAAARAAVLGLVEGAVPEAVDCLLPNGDVVRFAVNDGACEAGQAAHAMVIKDAGDDPDCT
DKAHLTADVRVLPGRAGEVVLCGGFGVGTVTMAGLGLEVGGPAINPVPRRNIEENVRAVGGPLLANAGIEVTISVPQGVE
MARKTLNARLGILGGISILGTTGIVKPYSTSAYRASVVQGVQVAATLGHGVVVLTTGGRTEQFAMKERPELPAACFVQMG
DFLRYALDEAVAQGLREVVIGGMVGKLTKIAQGETITHANRAEVDTQLLAELAARVGAPPDVCAEIAAAETARFGAERMQ
ALGLGEPFHHALAQAVVQTLTAPDRYGDRFHLTVLVCDFDGSKITEAASGPAATA

Sequences:

>Translated_375_residues
MMEKTVRRGTRTGFTTGACSAAAARAAVLGLVEGAVPEAVDCLLPNGDVVRFAVNDGACEAGQAAHAMVIKDAGDDPDCT
DKAHLTADVRVLPGRAGEVVLCGGFGVGTVTMAGLGLEVGGPAINPVPRRNIEENVRAVGGPLLANAGIEVTISVPQGVE
MARKTLNARLGILGGISILGTTGIVKPYSTSAYRASVVQGVQVAATLGHGVVVLTTGGRTEQFAMKERPELPAACFVQMG
DFLRYALDEAVAQGLREVVIGGMVGKLTKIAQGETITHANRAEVDTQLLAELAARVGAPPDVCAEIAAAETARFGAERMQ
ALGLGEPFHHALAQAVVQTLTAPDRYGDRFHLTVLVCDFDGSKITEAASGPAATA
>Mature_375_residues
MMEKTVRRGTRTGFTTGACSAAAARAAVLGLVEGAVPEAVDCLLPNGDVVRFAVNDGACEAGQAAHAMVIKDAGDDPDCT
DKAHLTADVRVLPGRAGEVVLCGGFGVGTVTMAGLGLEVGGPAINPVPRRNIEENVRAVGGPLLANAGIEVTISVPQGVE
MARKTLNARLGILGGISILGTTGIVKPYSTSAYRASVVQGVQVAATLGHGVVVLTTGGRTEQFAMKERPELPAACFVQMG
DFLRYALDEAVAQGLREVVIGGMVGKLTKIAQGETITHANRAEVDTQLLAELAARVGAPPDVCAEIAAAETARFGAERMQ
ALGLGEPFHHALAQAVVQTLTAPDRYGDRFHLTVLVCDFDGSKITEAASGPAATA

Specific function: May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A

COG id: COG1903

COG function: function code H; Cobalamin biosynthesis protein CbiD

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBID_ACIAC (A1TI97)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_968459.1
- ProteinModelPortal:   A1TI97
- SMR:   A1TI97
- STRING:   A1TI97
- GeneID:   4668865
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0071
- NMPDR:   fig|397945.5.peg.60
- eggNOG:   COG1903
- HOGENOM:   HBG705387
- OMA:   RRGWTTG
- ProtClustDB:   PRK00075
- BioCyc:   AAVE397945:AAVE_0071-MONOMER
- HAMAP:   MF_00787
- InterPro:   IPR002748
- PIRSF:   PIRSF026782
- TIGRFAMs:   TIGR00312

Pfam domain/function: PF01888 CbiD; SSF111342 Cbl_biosynth_CbiD

EC number: NA

Molecular weight: Translated: 38484; Mature: 38484

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEKTVRRGTRTGFTTGACSAAAARAAVLGLVEGAVPEAVDCLLPNGDVVRFAVNDGACE
CCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCC
AGQAAHAMVIKDAGDDPDCTDKAHLTADVRVLPGRAGEVVLCGGFGVGTVTMAGLGLEVG
CCCCCEEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCEEEECCCCHHHHHHHCCCEECC
GPAINPVPRRNIEENVRAVGGPLLANAGIEVTISVPQGVEMARKTLNARLGILGGISILG
CCCCCCCCCCCHHHHHHHHCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHC
TTGIVKPYSTSAYRASVVQGVQVAATLGHGVVVLTTGGRTEQFAMKERPELPAACFVQMG
CCCCCCCCCCHHHHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHH
DFLRYALDEAVAQGLREVVIGGMVGKLTKIAQGETITHANRAEVDTQLLAELAARVGAPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCCCH
DVCAEIAAAETARFGAERMQALGLGEPFHHALAQAVVQTLTAPDRYGDRFHLTVLVCDFD
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECC
GSKITEAASGPAATA
CCCHHHCCCCCCCCC
>Mature Secondary Structure
MMEKTVRRGTRTGFTTGACSAAAARAAVLGLVEGAVPEAVDCLLPNGDVVRFAVNDGACE
CCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCC
AGQAAHAMVIKDAGDDPDCTDKAHLTADVRVLPGRAGEVVLCGGFGVGTVTMAGLGLEVG
CCCCCEEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCEEEECCCCHHHHHHHCCCEECC
GPAINPVPRRNIEENVRAVGGPLLANAGIEVTISVPQGVEMARKTLNARLGILGGISILG
CCCCCCCCCCCHHHHHHHHCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHC
TTGIVKPYSTSAYRASVVQGVQVAATLGHGVVVLTTGGRTEQFAMKERPELPAACFVQMG
CCCCCCCCCCHHHHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHH
DFLRYALDEAVAQGLREVVIGGMVGKLTKIAQGETITHANRAEVDTQLLAELAARVGAPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCCCH
DVCAEIAAAETARFGAERMQALGLGEPFHHALAQAVVQTLTAPDRYGDRFHLTVLVCDFD
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECC
GSKITEAASGPAATA
CCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA