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The map label for this gene is dsbC [H]

Identifier: 119946909

GI number: 119946909

Start: 4074208

End: 4074963

Strand: Reverse

Name: dsbC [H]

Synonym: Ping_3303

Alternate gene names: 119946909

Gene position: 4074963-4074208 (Counterclockwise)

Preceding gene: 119946910

Following gene: 119946908

Centisome position: 89.37

GC content: 39.68

Gene sequence:

>756_bases
ATGGCGACTATTTTTTCAAAAACAGGGGTTATTTGTGTCTTTTTATTAAGCAGTTTTGCAGCCGTCTCAGCGACGTCTGA
ATCTCCCTCCTCGCTGGTGGTTGAGGAAATAACGACTAAAATGGAAAGCCTTAAGATCCCCGTTAATGAGATTAATAAGT
CAGCAGTAGAGGGATTATATGAAGTGATCTCCAATGGTGATATTTATTATATTAGTGAAGATGCAACCCATTTGTTGTAT
GGAAGTATTTACGCTTTAGACAATCAGATGGTCAATATTACTGAGCAGAAAAAAGCACAATTAAGTCGCCAAAAAGTCGC
TAAAAATATAGACAAAATAACCGCCTTTGAAAAAGACATGATTGTGTTTAAAGCGCAGGATGAGAAACACGTTGTCACTG
TTTTTACCGATCCTACCTGCAGTTACTGTCAGAAATTACATTCACAAATGGCTGACTATAATAAATTGGGTATTACTATT
CGCTATTTAGCATTTCCGCGAGCGGGTATTGATTCTTCAACCTACCATACTATGGTCTCAATATGGTGCTCAAACGATCC
TAAAAATGCGATGAATATGGCTAAAAAACGCCGTGAGATCCCCTCTGAAACCTGTGAAAACACCGTCAAGGAGCAATATC
AGCTTGGGCGTTTACTTGGGGTTAATGGCACACCGGCTTTGATTTTAGAAAATGGTACCCTCACCCCGGGTTATCTTCCT
CCTCAGCGTTTGCTGCAGTTGTTAGAGGAAAAATAA

Upstream 100 bases:

>100_bases
GGCAAATTAAAAAATTCACAAATCAGTACTTACTAGGCATAATCAACTCCTGAGTATTTTAGAAATACTCTCTTTATTCC
ACTAACAATATGAGGTTTTT

Downstream 100 bases:

>100_bases
ATCGGCGATTTTTTAATATAGTGCCCTTATAGCCAGATCATTTGCTGATGCCTGCATTCGCAAATGATCTGGCTATATTC
TTATTACAAAGCATTTGGTA

Product: thiol:disulfide interchange protein DsbC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MATIFSKTGVICVFLLSSFAAVSATSESPSSLVVEEITTKMESLKIPVNEINKSAVEGLYEVISNGDIYYISEDATHLLY
GSIYALDNQMVNITEQKKAQLSRQKVAKNIDKITAFEKDMIVFKAQDEKHVVTVFTDPTCSYCQKLHSQMADYNKLGITI
RYLAFPRAGIDSSTYHTMVSIWCSNDPKNAMNMAKKRREIPSETCENTVKEQYQLGRLLGVNGTPALILENGTLTPGYLP
PQRLLQLLEEK

Sequences:

>Translated_251_residues
MATIFSKTGVICVFLLSSFAAVSATSESPSSLVVEEITTKMESLKIPVNEINKSAVEGLYEVISNGDIYYISEDATHLLY
GSIYALDNQMVNITEQKKAQLSRQKVAKNIDKITAFEKDMIVFKAQDEKHVVTVFTDPTCSYCQKLHSQMADYNKLGITI
RYLAFPRAGIDSSTYHTMVSIWCSNDPKNAMNMAKKRREIPSETCENTVKEQYQLGRLLGVNGTPALILENGTLTPGYLP
PQRLLQLLEEK
>Mature_250_residues
ATIFSKTGVICVFLLSSFAAVSATSESPSSLVVEEITTKMESLKIPVNEINKSAVEGLYEVISNGDIYYISEDATHLLYG
SIYALDNQMVNITEQKKAQLSRQKVAKNIDKITAFEKDMIVFKAQDEKHVVTVFTDPTCSYCQKLHSQMADYNKLGITIR
YLAFPRAGIDSSTYHTMVSIWCSNDPKNAMNMAKKRREIPSETCENTVKEQYQLGRLLGVNGTPALILENGTLTPGYLPP
QRLLQLLEEK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=245, Percent_Identity=39.1836734693878, Blast_Score=195, Evalue=2e-51,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 28035; Mature: 27903

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIFSKTGVICVFLLSSFAAVSATSESPSSLVVEEITTKMESLKIPVNEINKSAVEGLY
CCCEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EVISNGDIYYISEDATHLLYGSIYALDNQMVNITEQKKAQLSRQKVAKNIDKITAFEKDM
HHHCCCCEEEECCCCCCHHHHHHEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCE
IVFKAQDEKHVVTVFTDPTCSYCQKLHSQMADYNKLGITIRYLAFPRAGIDSSTYHTMVS
EEEEECCCCEEEEEEECCCHHHHHHHHHHHHCCHHHCEEEEEEECCCCCCCCCHHEEEEE
IWCSNDPKNAMNMAKKRREIPSETCENTVKEQYQLGRLLGVNGTPALILENGTLTPGYLP
EEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
PQRLLQLLEEK
HHHHHHHHHCC
>Mature Secondary Structure 
ATIFSKTGVICVFLLSSFAAVSATSESPSSLVVEEITTKMESLKIPVNEINKSAVEGLY
CCEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EVISNGDIYYISEDATHLLYGSIYALDNQMVNITEQKKAQLSRQKVAKNIDKITAFEKDM
HHHCCCCEEEECCCCCCHHHHHHEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCE
IVFKAQDEKHVVTVFTDPTCSYCQKLHSQMADYNKLGITIRYLAFPRAGIDSSTYHTMVS
EEEEECCCCEEEEEEECCCHHHHHHHHHHHHCCHHHCEEEEEEECCCCCCCCCHHEEEEE
IWCSNDPKNAMNMAKKRREIPSETCENTVKEQYQLGRLLGVNGTPALILENGTLTPGYLP
EEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
PQRLLQLLEEK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]