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The map label for this gene is sdaA [H]

Identifier: 119946862

GI number: 119946862

Start: 4018965

End: 4020335

Strand: Direct

Name: sdaA [H]

Synonym: Ping_3256

Alternate gene names: 119946862

Gene position: 4018965-4020335 (Clockwise)

Preceding gene: 119946853

Following gene: 119946866

Centisome position: 88.14

GC content: 42.3

Gene sequence:

>1371_bases
ATGCTTTCAATTTTTGACATCTATAAAATCGGTATTGGCCCGTCAAGCTCACACACTAATGGTCCTATGATTGCAGGTTA
TCAGTTTACTTTATTACTCAAAGACAGTCTGCCTTTGGTAAATGAAATTAAGGTAGATCTGTTTGGATCTTTAGCGTTGA
CAGGTAAAGGCCACCATACTGACAAGGCGGTATTATTAGGTTTATTAGGATTTCAGCCCGAAACGATTAAAGTAAAAAGT
GCGAATCAACTTATTGAAAAAGTGAAAAAAACATTAAAAATGCCACTTTCGAATGAAAAATTAATCGACTTTGATCCTGA
AGAACAAATTAAATTCCATTTTGAAAATCTTCCTCTGCACGAGAATGGTATGTCGATCAGTGCTTTTGATATTAACGGGG
CCATGCTGTGCAGTGAAACCTATTATTCTATTGGTGGCGGATTTATTAAAACAGCGGCAGAATTAACCAGTGGTGACGCC
CCGAATAAAATTAAACTGCCTTTTGAATTTCATTCTGCGCAGGAGTTATTAAACAAAGCAGAGCAACAAGGTTTAAGTAT
TGGCGGCTTAGTACAGAAAAATGAATTAGCTTTTCGCAGCCAAAAAGAGATAGATAAAAAAACCGATCAACTTTGGAAAG
TAATGTGTTTGTGTTTACAACGCGGTTTGCAAACCGAAGGCATACTTGAAGGAGGATTAAACGTCACACGGCGTGCACCG
GCGTTATTAAAAACACTGGAAGCGAACCAGGCAACCGATAGCGATCCGATGACTATTATTGATTGGGTTAACCTCTTTGC
TTTCGCCGTCAGTGAAGAAAATGCAGCTGGCGGTCAGGTAGTTACATCGCCAACCAACGGTGCTGCGGGTGTTATTCCAG
CGGTCTTAACCTACTACCATAGATTTATCCATGAATTAGATACCAAACAATTAAAAGACTTCCTCGGTGTATCAGCGGCG
ATCGGCGTGCTTTATAAAATGAATGCCTCAATTTCTGGTGCCGAGGTCGGCTGTCAGGGAGAAATAGGGGTTTCATCATC
GATGGCGGCAGCGGGTCTAACGGCTATTCGAGGCGGCAGTAATGAGCAAATCTGCATGGCAGCTGAAATTGCCATGGAAC
ATTCGCTGGGCATGACCTGCGATCCGGTCGGTGGTTTAGTACAGATCCCCTGCATTGAACGTAATGCAATGGGGGCAATG
AAAGCCATTAATGCGTCCCGTATGGCATTAAAACGCAACAGCAAATCAATTATCTCTTTAGATAATGTTATTGAGACTAT
GTATCAGACAGGCAAAGATATGCACAGAAACTACCGGGAAACATCACTGGGCGGGTTAGCGATGATTCACAGGGGCCCAC
CCTGTGAATAG

Upstream 100 bases:

>100_bases
AAATAGATTCGCTATTATTTACGCTTTAATGCATATTCGAAGCGCGTTTTGATTTACTACAAAACAATCTTTTTATGCAA
CAATCATTAGGAATTCCCTT

Downstream 100 bases:

>100_bases
TTTTAAATAGTTTTAAATAGTTTTCTGCATTAATAAAACGGTCACCTTGATAAGTTAATGGTGGCCGTTTTAGATTGTCG
AAGTTATATTTAAAATTAGT

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH 1; L-serine deaminase 1; L-SD1 [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLSIFDIYKIGIGPSSSHTNGPMIAGYQFTLLLKDSLPLVNEIKVDLFGSLALTGKGHHTDKAVLLGLLGFQPETIKVKS
ANQLIEKVKKTLKMPLSNEKLIDFDPEEQIKFHFENLPLHENGMSISAFDINGAMLCSETYYSIGGGFIKTAAELTSGDA
PNKIKLPFEFHSAQELLNKAEQQGLSIGGLVQKNELAFRSQKEIDKKTDQLWKVMCLCLQRGLQTEGILEGGLNVTRRAP
ALLKTLEANQATDSDPMTIIDWVNLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLTYYHRFIHELDTKQLKDFLGVSAA
IGVLYKMNASISGAEVGCQGEIGVSSSMAAAGLTAIRGGSNEQICMAAEIAMEHSLGMTCDPVGGLVQIPCIERNAMGAM
KAINASRMALKRNSKSIISLDNVIETMYQTGKDMHRNYRETSLGGLAMIHRGPPCE

Sequences:

>Translated_456_residues
MLSIFDIYKIGIGPSSSHTNGPMIAGYQFTLLLKDSLPLVNEIKVDLFGSLALTGKGHHTDKAVLLGLLGFQPETIKVKS
ANQLIEKVKKTLKMPLSNEKLIDFDPEEQIKFHFENLPLHENGMSISAFDINGAMLCSETYYSIGGGFIKTAAELTSGDA
PNKIKLPFEFHSAQELLNKAEQQGLSIGGLVQKNELAFRSQKEIDKKTDQLWKVMCLCLQRGLQTEGILEGGLNVTRRAP
ALLKTLEANQATDSDPMTIIDWVNLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLTYYHRFIHELDTKQLKDFLGVSAA
IGVLYKMNASISGAEVGCQGEIGVSSSMAAAGLTAIRGGSNEQICMAAEIAMEHSLGMTCDPVGGLVQIPCIERNAMGAM
KAINASRMALKRNSKSIISLDNVIETMYQTGKDMHRNYRETSLGGLAMIHRGPPCE
>Mature_456_residues
MLSIFDIYKIGIGPSSSHTNGPMIAGYQFTLLLKDSLPLVNEIKVDLFGSLALTGKGHHTDKAVLLGLLGFQPETIKVKS
ANQLIEKVKKTLKMPLSNEKLIDFDPEEQIKFHFENLPLHENGMSISAFDINGAMLCSETYYSIGGGFIKTAAELTSGDA
PNKIKLPFEFHSAQELLNKAEQQGLSIGGLVQKNELAFRSQKEIDKKTDQLWKVMCLCLQRGLQTEGILEGGLNVTRRAP
ALLKTLEANQATDSDPMTIIDWVNLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLTYYHRFIHELDTKQLKDFLGVSAA
IGVLYKMNASISGAEVGCQGEIGVSSSMAAAGLTAIRGGSNEQICMAAEIAMEHSLGMTCDPVGGLVQIPCIERNAMGAM
KAINASRMALKRNSKSIISLDNVIETMYQTGKDMHRNYRETSLGGLAMIHRGPPCE

Specific function: Deaminates also threonine, particularly when it is present in high concentration [H]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=451, Percent_Identity=54.7671840354767, Blast_Score=500, Evalue=1e-143,
Organism=Escherichia coli, GI1789161, Length=451, Percent_Identity=54.1019955654102, Blast_Score=500, Evalue=1e-143,
Organism=Escherichia coli, GI48994925, Length=452, Percent_Identity=55.5309734513274, Blast_Score=492, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49267; Mature: 49267

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIFDIYKIGIGPSSSHTNGPMIAGYQFTLLLKDSLPLVNEIKVDLFGSLALTGKGHHT
CCEEEEEEEECCCCCCCCCCCCEEECEEEEEEEECCCCCHHHHHHEEEEEEEECCCCCCC
DKAVLLGLLGFQPETIKVKSANQLIEKVKKTLKMPLSNEKLIDFDPEEQIKFHFENLPLH
CHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHEEECCCCCC
ENGMSISAFDINGAMLCSETYYSIGGGFIKTAAELTSGDAPNKIKLPFEFHSAQELLNKA
CCCCEEEEEECCCEEEECCHHHHHCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHH
EQQGLSIGGLVQKNELAFRSQKEIDKKTDQLWKVMCLCLQRGLQTEGILEGGLNVTRRAP
HHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHH
ALLKTLEANQATDSDPMTIIDWVNLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLTYYH
HHHHHHHCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCEEEECCCCCCCHHHHHHHHHHH
RFIHELDTKQLKDFLGVSAAIGVLYKMNASISGAEVGCQGEIGVSSSMAAAGLTAIRGGS
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHCHHHCCCCC
NEQICMAAEIAMEHSLGMTCDPVGGLVQIPCIERNAMGAMKAINASRMALKRNSKSIISL
CCCEEEHHHHHHHHCCCCCCCCCCCEEECCEECCCHHHHHHHHHHHHHHHHCCCCCEEHH
DNVIETMYQTGKDMHRNYRETSLGGLAMIHRGPPCE
HHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure
MLSIFDIYKIGIGPSSSHTNGPMIAGYQFTLLLKDSLPLVNEIKVDLFGSLALTGKGHHT
CCEEEEEEEECCCCCCCCCCCCEEECEEEEEEEECCCCCHHHHHHEEEEEEEECCCCCCC
DKAVLLGLLGFQPETIKVKSANQLIEKVKKTLKMPLSNEKLIDFDPEEQIKFHFENLPLH
CHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHEEECCCCCC
ENGMSISAFDINGAMLCSETYYSIGGGFIKTAAELTSGDAPNKIKLPFEFHSAQELLNKA
CCCCEEEEEECCCEEEECCHHHHHCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHH
EQQGLSIGGLVQKNELAFRSQKEIDKKTDQLWKVMCLCLQRGLQTEGILEGGLNVTRRAP
HHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHH
ALLKTLEANQATDSDPMTIIDWVNLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLTYYH
HHHHHHHCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCEEEECCCCCCCHHHHHHHHHHH
RFIHELDTKQLKDFLGVSAAIGVLYKMNASISGAEVGCQGEIGVSSSMAAAGLTAIRGGS
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHCHHHCCCCC
NEQICMAAEIAMEHSLGMTCDPVGGLVQIPCIERNAMGAMKAINASRMALKRNSKSIISL
CCCEEEHHHHHHHHCCCCCCCCCCCEEECCEECCCHHHHHHHHHHHHHHHHCCCCCEEHH
DNVIETMYQTGKDMHRNYRETSLGGLAMIHRGPPCE
HHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2504697; 8436113; 9097040; 9278503 [H]