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The map label for this gene is apeB [H]

Identifier: 119945478

GI number: 119945478

Start: 2159928

End: 2161187

Strand: Reverse

Name: apeB [H]

Synonym: Ping_1777

Alternate gene names: 119945478

Gene position: 2161187-2159928 (Counterclockwise)

Preceding gene: 119945482

Following gene: 119945476

Centisome position: 47.4

GC content: 36.27

Gene sequence:

>1260_bases
ATGAATAAACAAAATTTTAACGAAGAGCTTTTAGGATTTTTAGATGCGTCTCCTACACCTTTTCATGCCACTTTAAATAT
GAGTATGATGTTAGAGAATGCTGGATTTATAAAGCTTGATGAACGCCAAAAATGGAAGCTCAAAGAGGGTAAGAAGTATT
TTGTAATGCGCAACGATTCTTCTGTTATCGCTTTTACATATCCTAAAGATAAAAACTACACAATAGTGGGTGCTCATACA
GATTCACCCAATATAAAACTAAAGCCAAAACCCGTTACTAAAGAGCATGGCGTTGTGAAATTTGGCGTTGAGCCTTATGG
AGGTCTTTTACTAAATCCTTGGTTTGACAGAGATCTCTCACTTGCAGGGCGTGTTTCTTATCTTGACTCTAAAAATGTTA
TTCAACATGTTTTGATTAATGTTAAAAAGGCTATTGCGATTATCCCATCACTTGCAATTCATTTGGATGAGAATGCTAAT
AAAGAGAGAACGGTAAATAAGCAGACAGATATCTCACCTATCCTTACAACAAATGATGATTTCGAGTTTGATGAGTTCTT
AAAATTGCAGCTTGAGAAGTTGGGGATTCAAGATGTTAAAGCGCTTTATGCAAATGAACTTAGTTTTTATGACACAGCGA
ATGCTTCATATGTAGGTTTAAATGACGACTTTATAGCGAGTGCAAGATTAGACAACCTTCTTAGCTGTTATGTTGGACTG
CTAAGTATATGCAATGTAGATGATGATAAACCTATGATGTTTATTGCCAGTGACCATGAAGAAGTTGGAAGTGAGTCAAC
CAGTGGTGCAAGTGGGAGCTTTTTAGAAAATACGCTTAGAAGAATGTATAACGATTATGAGGACTATATGCAGATGATAA
GAGGTTCGATTTTAATATCTGCTGATAACGCACATGCAATCCATCCAAACTTTCCATACAAACACGATGCTAATCATGCT
CCACACATCAATAAAGGCACTGTTATAAAGATAAATGCAAACCAGCGATATGCTTCAAACTCTACAACTATTTCAAGATT
TATGAATGTGGCTAACGCTGTAAATGAGCCGTATCAAGAGTTTGTAACAAGAAGTGATATGGGATGTGGTTCAACTATCG
GTCCATTAACTGCGACAAGACTTGGGATTGATACACTTGATGTTGGACTTCCTACTTTAGCAATGCACTCTATACGTGAG
CTTTGTGGTAGTGATGATGCACACTCTTTGTATAAAATCATTTTAGGATTTAGCAAGTAA

Upstream 100 bases:

>100_bases
AGCCCATACGAAAGCTTAAATTGATTTAAAATGGAGTCATCTTTGACTTCGCAAAGAATGTAGCGTTAAATTATTACTTA
CACTTTTGAAGGATTAAAAT

Downstream 100 bases:

>100_bases
TATCGACTGTAACACCAGAGGAACTAAATCTTTTAATATAGCAAACCGGCAAGGTTGAGTATAGGTAATTACAATCATGA
TATCTCTTTTTATAACCCAA

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNKQNFNEELLGFLDASPTPFHATLNMSMMLENAGFIKLDERQKWKLKEGKKYFVMRNDSSVIAFTYPKDKNYTIVGAHT
DSPNIKLKPKPVTKEHGVVKFGVEPYGGLLLNPWFDRDLSLAGRVSYLDSKNVIQHVLINVKKAIAIIPSLAIHLDENAN
KERTVNKQTDISPILTTNDDFEFDEFLKLQLEKLGIQDVKALYANELSFYDTANASYVGLNDDFIASARLDNLLSCYVGL
LSICNVDDDKPMMFIASDHEEVGSESTSGASGSFLENTLRRMYNDYEDYMQMIRGSILISADNAHAIHPNFPYKHDANHA
PHINKGTVIKINANQRYASNSTTISRFMNVANAVNEPYQEFVTRSDMGCGSTIGPLTATRLGIDTLDVGLPTLAMHSIRE
LCGSDDAHSLYKIILGFSK

Sequences:

>Translated_419_residues
MNKQNFNEELLGFLDASPTPFHATLNMSMMLENAGFIKLDERQKWKLKEGKKYFVMRNDSSVIAFTYPKDKNYTIVGAHT
DSPNIKLKPKPVTKEHGVVKFGVEPYGGLLLNPWFDRDLSLAGRVSYLDSKNVIQHVLINVKKAIAIIPSLAIHLDENAN
KERTVNKQTDISPILTTNDDFEFDEFLKLQLEKLGIQDVKALYANELSFYDTANASYVGLNDDFIASARLDNLLSCYVGL
LSICNVDDDKPMMFIASDHEEVGSESTSGASGSFLENTLRRMYNDYEDYMQMIRGSILISADNAHAIHPNFPYKHDANHA
PHINKGTVIKINANQRYASNSTTISRFMNVANAVNEPYQEFVTRSDMGCGSTIGPLTATRLGIDTLDVGLPTLAMHSIRE
LCGSDDAHSLYKIILGFSK
>Mature_419_residues
MNKQNFNEELLGFLDASPTPFHATLNMSMMLENAGFIKLDERQKWKLKEGKKYFVMRNDSSVIAFTYPKDKNYTIVGAHT
DSPNIKLKPKPVTKEHGVVKFGVEPYGGLLLNPWFDRDLSLAGRVSYLDSKNVIQHVLINVKKAIAIIPSLAIHLDENAN
KERTVNKQTDISPILTTNDDFEFDEFLKLQLEKLGIQDVKALYANELSFYDTANASYVGLNDDFIASARLDNLLSCYVGL
LSICNVDDDKPMMFIASDHEEVGSESTSGASGSFLENTLRRMYNDYEDYMQMIRGSILISADNAHAIHPNFPYKHDANHA
PHINKGTVIKINANQRYASNSTTISRFMNVANAVNEPYQEFVTRSDMGCGSTIGPLTATRLGIDTLDVGLPTLAMHSIRE
LCGSDDAHSLYKIILGFSK

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=448, Percent_Identity=38.1696428571429, Blast_Score=298, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI17552916, Length=448, Percent_Identity=40.1785714285714, Blast_Score=278, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6321905, Length=452, Percent_Identity=36.7256637168142, Blast_Score=276, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6322746, Length=457, Percent_Identity=28.2275711159737, Blast_Score=173, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 46824; Mature: 46824

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS01319 RBFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQNFNEELLGFLDASPTPFHATLNMSMMLENAGFIKLDERQKWKLKEGKKYFVMRNDS
CCCCCCCHHHHHHHCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCC
SVIAFTYPKDKNYTIVGAHTDSPNIKLKPKPVTKEHGVVKFGVEPYGGLLLNPWFDRDLS
CEEEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCEEEECCCCCCCEEECCCCCCCCC
LAGRVSYLDSKNVIQHVLINVKKAIAIIPSLAIHLDENANKERTVNKQTDISPILTTNDD
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEEECCCC
FEFDEFLKLQLEKLGIQDVKALYANELSFYDTANASYVGLNDDFIASARLDNLLSCYVGL
CCHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHH
LSICNVDDDKPMMFIASDHEEVGSESTSGASGSFLENTLRRMYNDYEDYMQMIRGSILIS
HHHCCCCCCCCEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEE
ADNAHAIHPNFPYKHDANHAPHINKGTVIKINANQRYASNSTTISRFMNVANAVNEPYQE
ECCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCCEECCCCHHHHHHHHHHHHHCHHHHH
FVTRSDMGCGSTIGPLTATRLGIDTLDVGLPTLAMHSIRELCGSDDAHSLYKIILGFSK
HHHHCCCCCCCCCCCCHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNKQNFNEELLGFLDASPTPFHATLNMSMMLENAGFIKLDERQKWKLKEGKKYFVMRNDS
CCCCCCCHHHHHHHCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCC
SVIAFTYPKDKNYTIVGAHTDSPNIKLKPKPVTKEHGVVKFGVEPYGGLLLNPWFDRDLS
CEEEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCEEEECCCCCCCEEECCCCCCCCC
LAGRVSYLDSKNVIQHVLINVKKAIAIIPSLAIHLDENANKERTVNKQTDISPILTTNDD
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEEECCCC
FEFDEFLKLQLEKLGIQDVKALYANELSFYDTANASYVGLNDDFIASARLDNLLSCYVGL
CCHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHH
LSICNVDDDKPMMFIASDHEEVGSESTSGASGSFLENTLRRMYNDYEDYMQMIRGSILIS
HHHCCCCCCCCEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEE
ADNAHAIHPNFPYKHDANHAPHINKGTVIKINANQRYASNSTTISRFMNVANAVNEPYQE
ECCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCCEECCCCHHHHHHHHHHHHHCHHHHH
FVTRSDMGCGSTIGPLTATRLGIDTLDVGLPTLAMHSIRELCGSDDAHSLYKIILGFSK
HHHHCCCCCCCCCCCCHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA